BMRB Entry 25799
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PDB ID:
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_anomalous, AVS_full
BMRB Entry DOI: doi:10.13018/BMR25799
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Title: NMR structure of human I-type lectin domain-glycan complex PubMed: 27357658
Deposition date: 2015-09-07 Original release date: 2016-07-05
Authors: Proepster, Johannes; Yang, Fan; Rabbani, Said; Ernst, Beat; Allain, Frederic; Schubert, Mario
Citation: Proepster, Johannes; Yang, Fan; Rabbani, Said; Ernst, Beat; Allain, Frederic; Schubert, Mario. "Structural basis for sulfation-dependent self-glycan recognition by the human immune-inhibitory receptor Siglec-8" Proc. Natl. Acad. Sci. U. S. A. 113, 4170-4179 (2016).
Assembly members:
Siglec-8, polymer, 145 residues, 16665.598 Da.
SUGAR_(5-MER), non-polymer, 975.920 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
Siglec-8: MEGDRQYGDGYLLQVQELVT
VQEGLSVHVPCSFSYPQDGW
TDSDPVHGYWFRAGDRPYQD
APVATNNPDREVQAETQGRF
QLLGDIWSNDCSLSIRDARK
RDKGSYFFRLERGSMKWSYK
SQLNYKTKQLSVFVTALTHG
SLVPR
SUGAR_(5-MER): XXXXX
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 623 |
| 15N chemical shifts | 154 |
| 1H chemical shifts | 1042 |