==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER OXIDOREDUCTASE 23-NOV-99 1DG5 . COMPND 2 MOLECULE: DIHYDROFOLATE REDUCTASE; . SOURCE 2 ORGANISM_SCIENTIFIC: MYCOBACTERIUM TUBERCULOSIS; . AUTHOR R.LI,R.SIRAWARAPORN,P.CHITNUMSUB,W.SIRAWARAPORN,J.WOODEN, . 159 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 8745.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 108 67.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 28 17.6 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 23 14.5 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 2 1.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 17 10.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 16 10.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 22 13.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 1 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 2 1 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 1 2 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 1 A M 0 0 76 0, 0.0 90,-2.5 0, 0.0 2,-0.5 0.000 360.0 360.0 360.0 118.8 1.1 9.6 0.8 2 2 A V E -a 91 0A 13 104,-0.4 106,-2.4 88,-0.2 107,-1.0 -0.983 360.0-176.5-117.4 126.6 3.6 11.0 3.4 3 3 A G E -ab 92 109A 0 88,-2.7 90,-3.0 -2,-0.5 2,-0.4 -0.898 16.3-143.7-122.6 153.7 4.8 14.5 2.9 4 4 A L E -ab 93 110A 0 105,-2.3 107,-2.5 -2,-0.3 2,-0.4 -0.907 15.2-172.2-113.1 143.9 7.3 16.6 4.8 5 5 A I E + b 0 111A 7 88,-2.0 2,-0.3 -2,-0.4 107,-0.2 -0.994 18.3 139.5-139.5 130.6 7.0 20.3 5.2 6 6 A W E - b 0 112A 12 105,-1.8 107,-1.9 -2,-0.4 2,-0.4 -0.982 41.2-128.3-159.4 166.9 9.5 22.8 6.7 7 7 A A E - b 0 113A 11 -2,-0.3 2,-0.3 105,-0.2 107,-0.2 -0.988 33.9-178.9-122.5 127.6 11.0 26.2 6.4 8 8 A Q E - b 0 114A 35 105,-2.9 107,-3.1 -2,-0.4 6,-0.2 -0.962 30.9-117.5-133.3 151.8 14.9 26.4 6.4 9 9 A A E > - b 0 115A 0 4,-2.4 3,-3.2 -2,-0.3 107,-0.2 -0.461 47.7-102.0 -74.1 153.6 17.6 29.0 6.2 10 10 A T T 3 S+ 0 0 74 105,-1.6 -1,-0.1 107,-0.4 106,-0.1 0.845 125.8 62.2 -46.9 -31.9 19.7 28.6 3.0 11 11 A S T 3 S- 0 0 23 106,-0.4 -1,-0.3 108,-0.1 110,-0.2 0.618 120.2-109.1 -70.0 -19.1 22.2 26.9 5.4 12 12 A G S < S+ 0 0 12 -3,-3.2 116,-2.5 1,-0.4 2,-0.2 0.309 71.2 140.9 104.7 -6.6 19.8 24.2 6.3 13 13 A V E +I 127 0B 0 106,-0.3 -4,-2.4 114,-0.2 -1,-0.4 -0.510 15.6 164.3 -71.6 130.3 19.1 25.4 9.9 14 14 A I E + 0 0 21 112,-2.7 2,-0.3 1,-0.4 113,-0.2 0.522 63.5 22.2-119.2 -18.0 15.4 25.0 10.8 15 15 A G E +I 126 0B 12 111,-1.7 111,-2.3 5,-0.2 -1,-0.4 -0.999 51.5 173.3-154.9 148.1 15.7 25.3 14.6 16 16 A R B > S+J 19 0C 58 3,-2.3 3,-1.8 -2,-0.3 109,-0.1 -0.944 75.8 1.3-155.5 130.1 17.9 26.8 17.3 17 17 A G T 3 S- 0 0 78 -2,-0.3 3,-0.1 1,-0.3 108,-0.1 0.760 128.8 -60.5 63.5 24.4 17.3 27.0 21.1 18 18 A G T 3 S+ 0 0 57 1,-0.3 -1,-0.3 3,-0.0 2,-0.2 0.526 120.6 93.1 80.5 6.6 14.0 25.3 20.6 19 19 A D B < S-J 16 0C 107 -3,-1.8 -3,-2.3 2,-0.0 -1,-0.3 -0.699 85.6-102.4-124.8 172.5 12.7 28.1 18.3 20 20 A I - 0 0 94 -2,-0.2 2,-0.9 -5,-0.2 -5,-0.2 -0.902 38.3-136.5 -92.0 122.8 12.6 28.9 14.6 21 21 A P S S+ 0 0 33 0, 0.0 2,-0.3 0, 0.0 -6,-0.1 -0.062 74.1 43.8 -76.2 36.1 15.4 31.5 14.2 22 22 A W S S- 0 0 22 -2,-0.9 2,-0.5 2,-0.0 -2,-0.1 -0.981 74.3-117.2-167.3 165.0 13.5 33.9 12.0 23 23 A R + 0 0 129 -2,-0.3 126,-0.3 124,-0.1 124,-0.1 -0.968 35.2 156.0-117.2 125.4 10.3 35.8 11.5 24 24 A L >> - 0 0 12 -2,-0.5 3,-1.9 1,-0.1 4,-0.5 -0.700 15.3-175.4-149.3 84.6 8.3 35.1 8.3 25 25 A P H 3> S+ 0 0 26 0, 0.0 4,-0.5 0, 0.0 3,-0.5 0.777 82.2 62.7 -56.3 -29.1 4.6 35.9 8.9 26 26 A E H 3> S+ 0 0 50 1,-0.2 4,-1.1 2,-0.2 5,-0.1 0.597 89.2 72.8 -73.3 -12.2 3.6 34.6 5.4 27 27 A D H X> S+ 0 0 37 -3,-1.9 4,-2.9 1,-0.2 3,-0.5 0.936 86.1 61.7 -67.5 -45.2 4.8 31.1 6.4 28 28 A Q H 3X S+ 0 0 136 -4,-0.5 4,-2.2 -3,-0.5 -1,-0.2 0.834 105.7 46.4 -49.7 -42.8 1.9 30.4 8.7 29 29 A A H 3X S+ 0 0 65 -4,-0.5 4,-2.3 2,-0.2 -1,-0.3 0.806 112.6 48.2 -73.5 -35.4 -0.6 30.7 5.9 30 30 A H H < S+ 0 0 0 -4,-2.5 3,-2.0 -5,-0.2 -2,-0.2 0.708 82.3 122.2 -87.8 -22.3 -1.7 20.9 6.1 36 36 A M T 3< S+ 0 0 50 -4,-3.0 24,-0.2 1,-0.3 23,-0.1 -0.072 81.9 9.9 -49.7 132.9 -5.3 21.9 6.7 37 37 A G T 3 S+ 0 0 62 22,-2.1 -1,-0.3 1,-0.3 23,-0.2 0.458 110.1 101.1 78.6 1.2 -7.8 19.0 7.1 38 38 A H S < S- 0 0 56 -3,-2.0 23,-1.7 21,-0.1 2,-0.4 -0.509 81.2 -93.8-112.2 176.2 -5.0 16.4 7.2 39 39 A T E -cd 61 91A 13 51,-1.2 53,-2.4 21,-0.2 2,-0.4 -0.763 40.8-156.9 -86.6 136.7 -3.3 14.3 9.8 40 40 A I E -cd 62 92A 0 21,-3.2 23,-3.0 -2,-0.4 2,-0.4 -0.977 3.3-157.9-120.1 132.4 -0.1 16.0 11.0 41 41 A V E +cd 63 93A 0 51,-2.9 53,-2.6 -2,-0.4 54,-0.6 -0.922 18.7 164.0-110.9 134.4 2.9 14.2 12.6 42 42 A M E -cd 64 95A 0 21,-2.2 23,-2.8 -2,-0.4 54,-0.2 -0.982 36.5-107.1-145.6 155.8 5.5 15.9 14.8 43 43 A G E >> -c 65 0A 7 52,-2.2 4,-2.0 -2,-0.3 3,-1.1 -0.483 41.0-105.6 -78.7 157.4 8.2 15.0 17.3 44 44 A R H 3> S+ 0 0 82 21,-1.6 4,-2.4 1,-0.3 5,-0.2 0.838 120.3 54.5 -51.0 -40.1 7.6 15.7 21.0 45 45 A R H 3> S+ 0 0 167 2,-0.2 4,-1.5 1,-0.2 -1,-0.3 0.818 105.9 51.1 -67.1 -33.1 9.9 18.6 21.0 46 46 A T H <> S+ 0 0 28 -3,-1.1 4,-1.2 49,-0.2 -2,-0.2 0.906 109.1 52.4 -69.2 -38.8 8.1 20.3 18.1 47 47 A W H >< S+ 0 0 4 -4,-2.0 3,-0.8 1,-0.2 -2,-0.2 0.935 109.7 48.0 -59.2 -47.6 4.9 19.8 20.1 48 48 A D H 3< S+ 0 0 69 -4,-2.4 -1,-0.2 1,-0.2 -2,-0.2 0.822 107.4 58.5 -61.4 -31.5 6.5 21.5 23.1 49 49 A S H 3< S+ 0 0 57 -4,-1.5 -1,-0.2 -5,-0.2 -2,-0.2 0.732 84.5 96.8 -70.7 -26.0 7.7 24.3 20.7 50 50 A L S << S- 0 0 27 -4,-1.2 5,-0.1 -3,-0.8 2,-0.0 -0.466 88.8-107.6 -68.4 133.7 4.1 25.1 19.7 51 51 A P >> - 0 0 66 0, 0.0 3,-1.5 0, 0.0 4,-0.9 -0.383 27.0-121.9 -60.2 140.0 2.6 28.0 21.6 52 52 A A T 34 S+ 0 0 80 1,-0.3 3,-0.4 2,-0.2 -2,-0.1 0.813 110.4 56.3 -53.4 -34.2 0.0 26.7 24.2 53 53 A K T 34 S+ 0 0 185 1,-0.2 -1,-0.3 0, 0.0 -3,-0.0 0.710 110.5 44.2 -74.6 -18.4 -2.7 28.9 22.6 54 54 A V T <4 S+ 0 0 52 -3,-1.5 -1,-0.2 3,-0.1 -2,-0.2 0.521 90.6 129.8-103.9 -4.9 -2.2 27.4 19.2 55 55 A R < + 0 0 74 -4,-0.9 2,-0.2 -3,-0.4 21,-0.1 -0.862 58.4 36.1-109.6 140.2 -1.9 23.7 20.1 56 56 A P S S- 0 0 46 0, 0.0 20,-0.1 0, 0.0 3,-0.1 0.527 102.4-116.4 -69.7 153.6 -3.3 21.3 19.0 57 57 A L > - 0 0 15 -2,-0.2 3,-0.9 1,-0.1 -2,-0.1 -0.481 37.3-113.8 -61.5 124.7 -3.2 22.9 15.5 58 58 A P T 3 S+ 0 0 88 0, 0.0 -21,-0.2 0, 0.0 -1,-0.1 -0.267 91.2 19.8 -63.4 142.8 -6.9 23.4 14.5 59 59 A G T 3 S+ 0 0 53 1,-0.2 -22,-2.1 -23,-0.1 2,-0.3 0.617 109.2 86.1 75.7 15.4 -8.5 21.5 11.7 60 60 A R S < S- 0 0 35 -3,-0.9 2,-0.8 -23,-0.2 -21,-0.2 -0.983 82.6-113.6-145.4 149.0 -5.9 18.8 11.7 61 61 A R E -c 39 0A 126 -23,-1.7 -21,-3.2 -2,-0.3 2,-0.5 -0.789 37.6-145.0 -86.3 112.1 -5.5 15.5 13.5 62 62 A N E -c 40 0A 3 -2,-0.8 15,-3.0 13,-0.5 2,-0.5 -0.718 17.7-174.0 -84.8 121.7 -2.4 16.2 15.6 63 63 A V E -ce 41 77A 1 -23,-3.0 -21,-2.2 -2,-0.5 2,-0.5 -0.971 4.4-163.9-118.7 126.4 -0.1 13.2 16.1 64 64 A V E -ce 42 78A 0 13,-2.8 15,-2.4 -2,-0.5 2,-0.5 -0.947 9.8-145.6-115.0 125.7 2.9 13.4 18.5 65 65 A L E +ce 43 79A 19 -23,-2.8 -21,-1.6 -2,-0.5 2,-0.3 -0.754 32.3 155.1 -90.0 126.9 5.8 10.9 18.5 66 66 A S - 0 0 10 13,-2.5 -2,-0.0 -2,-0.5 5,-0.0 -0.995 45.8-143.5-150.9 149.0 7.3 10.1 21.9 67 67 A R S S+ 0 0 227 -2,-0.3 2,-0.6 3,-0.0 13,-0.1 0.558 82.4 91.8 -87.2 -10.2 9.2 7.3 23.5 68 68 A Q > - 0 0 76 1,-0.2 3,-1.3 11,-0.1 -2,-0.0 -0.777 63.5-159.7 -85.2 117.9 7.5 8.0 26.8 69 69 A A T 3 S+ 0 0 109 -2,-0.6 -1,-0.2 1,-0.2 9,-0.1 0.779 93.3 53.1 -68.6 -20.5 4.4 5.8 27.0 70 70 A D T 3 S+ 0 0 116 -3,-0.1 -1,-0.2 2,-0.1 -2,-0.0 0.280 76.5 139.5 -94.3 3.0 3.0 8.3 29.6 71 71 A F < - 0 0 38 -3,-1.3 2,-0.5 1,-0.1 7,-0.1 -0.298 44.1-142.4 -58.0 133.3 3.5 11.5 27.6 72 72 A M + 0 0 167 2,-0.0 2,-0.3 1,-0.0 -1,-0.1 -0.874 29.3 162.0-101.0 122.4 0.6 14.0 28.0 73 73 A A > - 0 0 14 -2,-0.5 3,-2.1 3,-0.2 2,-0.1 -0.758 31.1-139.7-142.3 91.3 -0.5 15.9 24.9 74 74 A S T 3 S+ 0 0 105 -2,-0.3 3,-0.1 1,-0.3 -2,-0.0 -0.263 86.1 5.6 -55.9 123.4 -4.0 17.5 25.2 75 75 A G T 3 S+ 0 0 63 1,-0.3 -13,-0.5 -2,-0.1 2,-0.3 0.547 115.6 95.3 81.2 6.7 -5.9 17.3 22.0 76 76 A A S < S- 0 0 24 -3,-2.1 2,-0.6 -15,-0.1 -1,-0.3 -0.879 75.4-117.9-128.5 161.0 -3.3 15.2 20.3 77 77 A E E -e 63 0A 66 -15,-3.0 -13,-2.8 -2,-0.3 2,-0.5 -0.886 25.7-153.2 -99.7 114.8 -2.6 11.5 19.7 78 78 A V E +e 64 0A 46 -2,-0.6 2,-0.3 -15,-0.2 -13,-0.2 -0.781 19.5 176.1 -90.3 124.6 0.7 10.3 21.4 79 79 A V E -e 65 0A 9 -15,-2.4 -13,-2.5 -2,-0.5 -11,-0.1 -0.860 29.3-145.4-123.6 159.1 2.3 7.3 19.7 80 80 A G S S+ 0 0 47 -2,-0.3 2,-0.3 -15,-0.2 -15,-0.1 0.521 78.4 39.2-104.3 -4.0 5.5 5.5 20.3 81 81 A S S > S- 0 0 28 1,-0.1 4,-0.8 -14,-0.0 3,-0.4 -0.965 74.6-121.2-143.4 159.7 6.6 4.5 16.8 82 82 A L H > S+ 0 0 18 -2,-0.3 4,-2.0 1,-0.2 3,-0.4 0.844 111.1 60.5 -68.3 -35.8 6.6 6.0 13.3 83 83 A E H 4 S+ 0 0 148 1,-0.2 -1,-0.2 2,-0.2 4,-0.1 0.829 104.7 49.2 -61.3 -34.3 4.4 3.1 12.0 84 84 A E H 4 S+ 0 0 94 -3,-0.4 3,-0.3 1,-0.2 -1,-0.2 0.724 112.6 49.0 -76.3 -23.8 1.6 4.0 14.4 85 85 A A H < S+ 0 0 2 -4,-0.8 3,-0.4 -3,-0.4 -2,-0.2 0.799 105.3 55.8 -85.9 -29.3 1.9 7.7 13.3 86 86 A L < + 0 0 24 -4,-2.0 -1,-0.2 1,-0.2 -2,-0.1 0.260 67.4 112.4 -91.1 14.7 1.8 7.2 9.5 87 87 A T + 0 0 100 -3,-0.3 -1,-0.2 -4,-0.1 -2,-0.1 0.677 54.7 92.9 -62.9 -19.4 -1.5 5.2 9.2 88 88 A S S S- 0 0 22 -3,-0.4 3,-0.2 1,-0.1 -50,-0.0 -0.509 78.7-128.7 -79.2 146.7 -3.4 8.0 7.3 89 89 A P S S+ 0 0 111 0, 0.0 2,-0.5 0, 0.0 -1,-0.1 0.803 103.6 32.9 -59.3 -39.7 -3.4 8.1 3.5 90 90 A E S S+ 0 0 65 -88,-0.0 -51,-1.2 2,-0.0 2,-0.4 -0.921 79.9 166.7-124.9 104.2 -2.3 11.7 3.5 91 91 A T E -ad 2 39A 0 -90,-2.5 -88,-2.7 -2,-0.5 2,-0.5 -0.950 21.6-154.8-119.2 137.9 0.0 12.6 6.3 92 92 A W E -ad 3 40A 0 -53,-2.4 -51,-2.9 -2,-0.4 2,-0.8 -0.962 8.3-148.9-115.6 123.0 2.2 15.6 6.8 93 93 A V E -ad 4 41A 0 -90,-3.0 -88,-2.0 -2,-0.5 -51,-0.2 -0.831 18.6-179.7 -87.9 112.5 5.3 15.5 8.9 94 94 A I E - 0 0 15 -53,-2.6 2,-0.2 -2,-0.8 -52,-0.2 0.266 44.1 -12.8-100.6 9.4 5.5 19.0 10.3 95 95 A G E + d 0 42A 2 -54,-0.6 -52,-2.2 1,-0.1 -1,-0.2 -0.566 59.0 89.1 157.4 162.7 8.6 18.7 12.4 96 96 A G > - 0 0 16 -2,-0.2 4,-2.1 -54,-0.2 5,-0.2 0.001 50.6-121.1 107.8 133.0 11.5 17.9 14.3 97 97 A G H > S+ 0 0 20 2,-0.2 4,-1.5 1,-0.2 5,-0.1 0.909 119.6 48.9 -61.8 -36.4 14.9 17.7 12.7 98 98 A Q H > S+ 0 0 121 1,-0.2 4,-2.1 2,-0.2 -1,-0.2 0.938 110.7 47.0 -65.8 -48.9 14.8 14.1 14.2 99 99 A V H > S+ 0 0 9 1,-0.2 4,-2.6 2,-0.2 -1,-0.2 0.841 108.0 55.6 -65.9 -31.3 11.4 13.2 12.9 100 100 A Y H X S+ 0 0 11 -4,-2.1 4,-1.8 2,-0.2 -1,-0.2 0.898 109.9 47.2 -66.0 -40.7 12.1 14.5 9.4 101 101 A A H < S+ 0 0 66 -4,-1.5 -2,-0.2 2,-0.2 -1,-0.2 0.900 113.7 48.5 -64.4 -42.1 15.1 12.2 9.2 102 102 A L H < S+ 0 0 90 -4,-2.1 -2,-0.2 1,-0.2 -1,-0.2 0.899 119.3 37.2 -64.5 -43.6 13.0 9.3 10.6 103 103 A A H >X S+ 0 0 0 -4,-2.6 3,-1.4 1,-0.2 4,-0.7 0.622 89.2 92.7 -88.0 -16.1 10.1 9.9 8.1 104 104 A L G >< S+ 0 0 32 -4,-1.8 3,-1.7 1,-0.3 -1,-0.2 0.888 82.7 54.9 -47.9 -48.9 12.1 10.9 5.0 105 105 A P G 34 S+ 0 0 91 0, 0.0 -1,-0.3 0, 0.0 -2,-0.1 0.809 107.9 49.9 -60.7 -22.2 12.2 7.4 3.6 106 106 A Y G <4 S+ 0 0 144 -3,-1.4 -104,-0.4 -4,-0.2 -2,-0.2 0.572 96.4 102.8 -87.7 -9.8 8.4 7.0 3.8 107 107 A A << + 0 0 2 -3,-1.7 -104,-0.2 -4,-0.7 3,-0.1 -0.481 36.6 169.5 -84.3 145.1 8.0 10.3 2.0 108 108 A T S S+ 0 0 43 -106,-2.4 50,-1.4 1,-0.2 2,-0.3 0.271 72.7 48.6-127.6 2.8 7.0 11.1 -1.6 109 109 A R E -bF 3 157A 76 -107,-1.0 -105,-2.3 48,-0.2 2,-0.4 -0.997 54.8-175.8-146.6 142.2 6.4 14.8 -1.2 110 110 A C E -bF 4 156A 0 46,-2.1 46,-2.7 -2,-0.3 2,-0.6 -0.995 7.6-164.7-138.0 130.6 8.3 17.7 0.4 111 111 A E E -bF 5 155A 10 -107,-2.5 -105,-1.8 -2,-0.4 2,-0.4 -0.971 23.2-176.1-117.5 110.5 7.0 21.3 0.6 112 112 A V E -bF 6 154A 5 42,-2.2 42,-3.0 -2,-0.6 2,-0.5 -0.902 23.0-160.9-118.4 140.6 9.9 23.6 1.4 113 113 A T E -bF 7 153A 3 -107,-1.9 -105,-2.9 -2,-0.4 2,-0.5 -0.970 14.2-154.9-116.0 117.8 10.3 27.2 2.2 114 114 A E E -bF 8 152A 21 38,-3.2 38,-1.9 -2,-0.5 2,-0.6 -0.871 5.5-155.2 -96.3 126.8 13.8 28.6 1.8 115 115 A V E -bF 9 151A 0 -107,-3.1 2,-2.3 -2,-0.5 -105,-1.6 -0.905 12.7-139.6-103.4 118.5 14.6 31.7 3.9 116 116 A D E + F 0 150A 66 34,-2.8 34,-0.5 -2,-0.6 2,-0.3 -0.460 56.8 129.7 -77.7 71.5 17.3 33.9 2.5 117 117 A I - 0 0 25 -2,-2.3 2,-0.9 32,-0.1 -106,-0.4 -0.949 64.6-116.8-127.6 142.6 18.9 34.7 5.9 118 118 A G + 0 0 72 -2,-0.3 -2,-0.1 -108,-0.1 -109,-0.0 -0.737 56.3 141.2 -80.9 109.2 22.6 34.4 6.9 119 119 A L - 0 0 27 -2,-0.9 -106,-0.3 -106,-0.0 -110,-0.1 -0.527 34.2-158.5-153.2 74.5 22.6 31.8 9.6 120 120 A P - 0 0 93 0, 0.0 -108,-0.1 0, 0.0 2,-0.0 -0.159 36.1 -91.6 -54.1 149.0 25.5 29.3 9.5 121 121 A R - 0 0 157 -110,-0.2 2,-0.3 4,-0.0 6,-0.0 -0.347 41.5-164.6 -64.9 145.7 25.0 26.0 11.2 122 122 A E > - 0 0 112 -3,-0.1 3,-2.0 -2,-0.0 -1,-0.0 -0.939 36.4 -84.1-129.1 148.4 26.0 25.7 14.9 123 123 A A T 3 S+ 0 0 108 -2,-0.3 0, 0.0 1,-0.3 0, 0.0 -0.269 115.3 22.3 -53.8 131.4 26.5 22.5 16.9 124 124 A G T 3 S+ 0 0 89 1,-0.3 -1,-0.3 -108,-0.0 -107,-0.1 0.375 87.6 139.1 93.5 -6.1 23.2 21.3 18.2 125 125 A D < - 0 0 21 -3,-2.0 2,-0.4 -109,-0.1 -1,-0.3 -0.341 59.7-111.9 -70.2 153.9 20.9 23.1 15.7 126 126 A A E -I 15 0B 35 -111,-2.3 -112,-2.7 -2,-0.0 -111,-1.7 -0.722 42.7-160.5 -85.0 132.7 17.9 21.3 14.2 127 127 A L E -I 13 0B 73 -2,-0.4 -114,-0.2 -114,-0.2 -115,-0.1 -0.898 16.8-113.4-120.2 154.2 18.6 20.7 10.5 128 128 A A - 0 0 15 -116,-2.5 2,-0.1 -2,-0.3 -31,-0.1 -0.372 41.8-100.2 -77.6 153.5 16.5 20.0 7.5 129 129 A P - 0 0 19 0, 0.0 2,-0.5 0, 0.0 -1,-0.1 -0.456 36.0-116.4 -74.6 151.0 16.9 16.7 5.7 130 130 A V - 0 0 130 -2,-0.1 2,-0.7 -3,-0.1 -3,-0.0 -0.796 22.2-140.5 -90.3 129.9 19.0 16.6 2.6 131 131 A L - 0 0 39 -2,-0.5 -1,-0.0 2,-0.0 2,-0.0 -0.828 19.0-159.3 -94.2 115.5 17.1 15.7 -0.6 132 132 A D > - 0 0 94 -2,-0.7 3,-1.4 1,-0.1 -1,-0.0 -0.058 41.5 -76.2 -78.6-168.8 19.1 13.4 -2.9 133 133 A E T 3 S+ 0 0 174 1,-0.3 -1,-0.1 3,-0.0 -2,-0.0 0.357 115.5 81.4 -78.2 9.9 18.6 12.9 -6.6 134 134 A T T 3 S+ 0 0 70 24,-0.0 2,-0.3 2,-0.0 -1,-0.3 0.702 83.4 84.9 -81.0 -16.0 15.6 10.6 -6.2 135 135 A W < - 0 0 9 -3,-1.4 2,-0.4 23,-0.1 23,-0.2 -0.648 63.4-160.1 -91.8 137.8 13.7 13.9 -5.8 136 136 A R E -G 157 0A 123 21,-2.8 21,-2.0 -2,-0.3 2,-0.3 -0.949 22.1-171.5-112.6 132.3 12.3 16.1 -8.6 137 137 A G E -G 156 0A 46 -2,-0.4 2,-0.4 19,-0.2 19,-0.2 -0.850 27.0-151.4-132.7 164.3 11.6 19.7 -7.8 138 138 A E E -G 155 0A 105 17,-1.8 17,-1.9 -2,-0.3 2,-0.5 -0.998 20.4-148.2-128.4 125.2 10.1 23.0 -8.9 139 139 A T E -G 154 0A 72 -2,-0.4 15,-0.2 15,-0.2 3,-0.1 -0.836 11.0-148.4 -98.1 125.7 11.4 26.3 -7.5 140 140 A G - 0 0 31 13,-3.0 2,-0.2 -2,-0.5 -1,-0.0 -0.226 33.8 -79.2 -81.5 178.1 9.1 29.2 -7.1 141 141 A E - 0 0 158 1,-0.1 12,-0.3 11,-0.1 -1,-0.1 -0.565 46.9-105.6 -83.0 141.9 10.0 32.9 -7.4 142 142 A W - 0 0 63 -2,-0.2 2,-0.3 10,-0.1 10,-0.2 -0.311 42.8-174.1 -61.3 145.6 11.8 34.7 -4.6 143 143 A R E -H 151 0A 124 8,-2.4 8,-2.4 6,-0.0 2,-0.5 -0.931 24.7-115.4-138.4 159.6 9.5 37.1 -2.8 144 144 A F E -H 150 0A 152 -2,-0.3 6,-0.2 6,-0.2 2,-0.1 -0.899 24.0-146.2-103.0 125.6 10.0 39.7 -0.0 145 145 A S > - 0 0 5 4,-3.0 3,-1.8 -2,-0.5 -121,-0.0 -0.449 27.1-115.1 -77.7 159.5 8.4 39.1 3.3 146 146 A R T 3 S+ 0 0 196 1,-0.3 -1,-0.1 2,-0.1 -122,-0.1 0.664 118.0 68.1 -72.8 -9.4 7.2 42.1 5.3 147 147 A S T 3 S- 0 0 42 2,-0.2 -1,-0.3 -124,-0.1 3,-0.1 0.572 120.8-112.4 -79.5 -7.8 9.8 41.1 7.8 148 148 A G S < S+ 0 0 47 -3,-1.8 2,-0.3 1,-0.3 -2,-0.1 0.335 77.4 127.9 95.0 -7.9 12.3 42.0 5.1 149 149 A L - 0 0 22 -126,-0.3 -4,-3.0 -5,-0.1 -1,-0.3 -0.629 56.6-132.8 -85.5 139.5 13.5 38.5 4.5 150 150 A R E +FH 116 144A 83 -34,-0.5 -34,-2.8 -2,-0.3 2,-0.3 -0.676 35.6 169.9 -85.9 143.0 13.5 37.2 0.9 151 151 A Y E -FH 115 143A 19 -8,-2.4 -8,-2.4 -2,-0.3 2,-0.3 -0.982 17.7-166.1-151.1 160.5 12.0 33.7 0.7 152 152 A R E -F 114 0A 56 -38,-1.9 -38,-3.2 -2,-0.3 2,-0.3 -0.988 18.3-124.7-149.0 154.8 10.9 31.1 -1.9 153 153 A L E -F 113 0A 25 -2,-0.3 -13,-3.0 -12,-0.3 2,-0.4 -0.787 18.7-165.5-104.2 143.6 8.9 27.9 -2.0 154 154 A Y E -FG 112 139A 35 -42,-3.0 -42,-2.2 -2,-0.3 2,-0.5 -0.962 4.7-159.5-124.9 145.9 10.0 24.6 -3.4 155 155 A S E -FG 111 138A 34 -17,-1.9 -17,-1.8 -2,-0.4 2,-0.3 -0.988 15.0-178.1-130.2 118.7 7.8 21.5 -4.3 156 156 A Y E +FG 110 137A 56 -46,-2.7 -46,-2.1 -2,-0.5 2,-0.3 -0.906 4.6 170.4-118.2 152.0 9.5 18.2 -4.5 157 157 A H E +FG 109 136A 73 -21,-2.0 -21,-2.8 -2,-0.3 2,-0.3 -0.939 8.1 174.1-152.6 162.7 8.1 14.8 -5.3 158 158 A R 0 0 42 -50,-1.4 -23,-0.1 -2,-0.3 -24,-0.0 -0.931 360.0 360.0-163.9 158.1 9.3 11.2 -6.1 159 159 A S 0 0 157 -2,-0.3 -51,-0.1 -25,-0.3 -24,-0.1 0.480 360.0 360.0-103.1 360.0 7.5 8.0 -6.7