==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=25-MAR-2012 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE/ANTIBIOTIC 27-MAY-10 3N7W . COMPND 2 MOLECULE: BETA-LACTAMASE; . SOURCE 2 ORGANISM_SCIENTIFIC: MYCOBACTERIUM TUBERCULOSIS; . AUTHOR L.W.TREMBLAY,J.S.BLANCHARD . 265 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 10906.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 181 68.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 37 14.0 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 5 1.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 39 14.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 84 31.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 5 1.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 0 0 0 0 2 3 2 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 1 2 1 0 1 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 2 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 43 A D > 0 0 130 0, 0.0 4,-2.0 0, 0.0 5,-0.1 0.000 360.0 360.0 360.0 126.7 -31.6 9.8 -8.2 2 44 A L H > + 0 0 44 1,-0.2 4,-2.5 2,-0.2 5,-0.2 0.891 360.0 49.1 -62.9 -47.2 -29.8 7.4 -5.8 3 45 A A H > S+ 0 0 48 1,-0.2 4,-2.3 2,-0.2 -1,-0.2 0.877 111.3 52.8 -61.0 -37.7 -30.9 4.1 -7.2 4 46 A D H > S+ 0 0 92 2,-0.2 4,-2.1 1,-0.2 -1,-0.2 0.902 108.6 49.4 -62.5 -42.4 -29.9 5.3 -10.7 5 47 A R H X S+ 0 0 132 -4,-2.0 4,-1.9 2,-0.2 -2,-0.2 0.907 111.3 48.7 -65.0 -43.3 -26.4 6.2 -9.3 6 48 A F H X S+ 0 0 2 -4,-2.5 4,-2.1 2,-0.2 -2,-0.2 0.900 111.1 50.2 -62.8 -41.2 -26.0 2.8 -7.7 7 49 A A H X S+ 0 0 21 -4,-2.3 4,-1.9 2,-0.2 -1,-0.2 0.887 107.5 54.4 -65.3 -37.2 -27.1 1.1 -11.0 8 50 A E H X S+ 0 0 58 -4,-2.1 4,-2.2 1,-0.2 -1,-0.2 0.900 107.9 50.3 -58.9 -42.3 -24.5 3.2 -12.9 9 51 A L H X S+ 0 0 6 -4,-1.9 4,-2.1 2,-0.2 -2,-0.2 0.878 105.9 55.9 -65.2 -38.7 -21.8 2.0 -10.5 10 52 A E H <>S+ 0 0 17 -4,-2.1 5,-2.3 1,-0.2 4,-0.5 0.925 110.7 44.1 -58.5 -43.7 -22.9 -1.6 -11.1 11 53 A R H ><5S+ 0 0 175 -4,-1.9 3,-0.7 3,-0.2 -2,-0.2 0.902 111.4 54.6 -67.4 -37.8 -22.4 -1.2 -14.8 12 54 A R H 3<5S+ 0 0 146 -4,-2.2 -2,-0.2 1,-0.2 -1,-0.2 0.870 121.2 28.9 -63.0 -39.7 -19.1 0.6 -14.3 13 55 A Y T 3<5S- 0 0 16 -4,-2.1 -1,-0.2 -5,-0.1 -2,-0.2 0.265 103.1-121.5-107.1 11.0 -17.6 -2.2 -12.2 14 56 A D T < 5S+ 0 0 101 -3,-0.7 227,-0.4 -4,-0.5 2,-0.3 0.940 72.6 134.9 39.6 58.0 -19.5 -5.1 -13.8 15 57 A A < - 0 0 18 -5,-2.3 2,-0.5 -6,-0.2 224,-0.2 -0.774 65.3-125.9-130.3 165.1 -20.7 -5.7 -10.2 16 58 A R E -A 238 0A 66 222,-2.5 222,-1.9 -2,-0.3 2,-0.4 -0.985 35.8-165.2-110.4 126.6 -23.7 -6.4 -8.0 17 59 A L E -A 237 0A 0 -2,-0.5 2,-0.4 220,-0.2 220,-0.2 -0.948 11.3-170.5-118.0 136.0 -23.9 -3.8 -5.3 18 60 A G E +A 236 0A 0 218,-2.9 218,-2.6 -2,-0.4 2,-0.4 -0.989 8.3 179.9-126.2 137.3 -25.9 -3.8 -2.1 19 61 A V E +AB 235 32A 0 13,-2.6 13,-2.4 -2,-0.4 2,-0.3 -0.998 5.7 174.6-136.8 134.4 -26.4 -0.8 0.2 20 62 A Y E +AB 234 31A 21 214,-2.2 214,-2.5 -2,-0.4 11,-0.2 -0.967 8.7 171.4-141.3 134.1 -28.3 -0.3 3.5 21 63 A V E - B 0 30A 1 9,-2.4 9,-2.2 -2,-0.3 212,-0.2 -0.965 35.4-126.0-131.1 114.8 -28.5 2.7 5.9 22 64 A P - 0 0 5 0, 0.0 210,-0.2 0, 0.0 5,-0.1 -0.215 30.8 -99.4 -58.5 149.0 -31.1 2.3 8.6 23 65 A A + 0 0 58 6,-0.1 2,-0.3 208,-0.1 5,-0.2 -0.373 50.7 171.1 -61.2 145.1 -33.7 5.0 9.1 24 66 A T B > -E 27 0B 51 3,-1.6 3,-2.0 -3,-0.1 2,-0.7 -0.857 50.2 -34.4-167.1 132.8 -32.9 7.5 11.9 25 67 A G T 3 S- 0 0 84 -2,-0.3 -2,-0.0 1,-0.3 0, 0.0 -0.480 130.2 -13.5 59.5-101.4 -34.2 10.8 13.1 26 68 A T T 3 S+ 0 0 145 -2,-0.7 2,-0.4 2,-0.1 -1,-0.3 0.125 113.3 97.8-119.5 15.3 -35.4 12.5 10.0 27 69 A T B < -E 24 0B 32 -3,-2.0 -3,-1.6 -5,-0.1 2,-0.1 -0.915 65.9-133.3-108.4 136.2 -33.7 10.3 7.3 28 70 A A - 0 0 83 -2,-0.4 -2,-0.1 -5,-0.2 -7,-0.0 -0.464 42.0 -86.8 -73.6 153.9 -35.5 7.5 5.4 29 71 A A - 0 0 35 -2,-0.1 2,-0.5 -6,-0.1 -1,-0.1 -0.335 37.5-136.9 -56.0 141.7 -33.7 4.2 5.1 30 72 A I E +B 21 0A 14 -9,-2.2 -9,-2.4 -3,-0.1 2,-0.4 -0.927 33.0 172.7-101.8 127.8 -31.3 4.0 2.1 31 73 A E E +B 20 0A 120 -2,-0.5 2,-0.3 -11,-0.2 -11,-0.2 -0.983 20.2 162.7-144.8 130.6 -31.7 0.6 0.4 32 74 A Y E S-B 19 0A 30 -13,-2.4 -13,-2.6 -2,-0.4 -2,-0.0 -0.923 89.3 -22.8-144.8 116.6 -30.4 -0.9 -2.8 33 75 A R S > S+ 0 0 95 -2,-0.3 3,-1.5 -15,-0.2 125,-0.1 0.819 91.5 154.3 49.9 30.8 -30.5 -4.7 -3.2 34 76 A A T 3 + 0 0 5 1,-0.3 124,-2.6 -15,-0.2 125,-0.4 0.704 64.7 45.0 -68.2 -20.8 -30.6 -4.5 0.6 35 77 A D T 3 S+ 0 0 108 122,-0.2 -1,-0.3 121,-0.1 2,-0.2 0.351 89.0 105.6-105.4 5.2 -32.3 -7.8 1.1 36 78 A E S < S- 0 0 65 -3,-1.5 2,-0.3 1,-0.1 122,-0.2 -0.603 77.4-108.9 -81.0 146.2 -30.2 -9.8 -1.3 37 79 A R + 0 0 68 -2,-0.2 2,-0.3 119,-0.1 119,-0.2 -0.555 38.3 176.9 -76.4 135.4 -27.7 -12.2 0.1 38 80 A F E -F 155 0C 4 117,-2.5 117,-2.5 -2,-0.3 200,-0.0 -0.976 40.3 -92.7-129.4 148.5 -23.9 -11.4 -0.1 39 81 A A E -F 154 0C 8 -2,-0.3 115,-0.3 115,-0.2 198,-0.2 -0.353 27.4-140.3 -54.3 135.2 -21.0 -13.3 1.3 40 82 A F > + 0 0 0 113,-2.6 3,-1.8 95,-0.2 -1,-0.1 0.888 34.8 172.4 -54.8 -44.8 -20.0 -12.1 4.8 41 83 A C G > S- 0 0 0 112,-0.5 3,-1.3 102,-0.4 4,-0.1 -0.282 71.2 -24.5 45.4-146.7 -16.3 -12.5 4.0 42 84 A S G > S+ 0 0 12 1,-0.3 3,-2.0 169,-0.2 4,-0.3 0.537 118.7 91.9 -69.5 -4.3 -14.4 -10.9 7.0 43 85 A T G X S+ 0 0 0 -3,-1.8 3,-1.4 1,-0.3 -1,-0.3 0.798 73.5 71.6 -60.3 -23.5 -17.3 -8.6 8.0 44 86 A F G <> S+ 0 0 2 -3,-1.3 4,-2.0 1,-0.2 -1,-0.3 0.698 78.8 77.8 -62.0 -20.9 -18.4 -11.4 10.4 45 87 A K H <> S+ 0 0 7 -3,-2.0 4,-2.0 2,-0.2 -1,-0.2 0.775 86.0 60.0 -64.4 -27.2 -15.4 -10.7 12.6 46 88 A A H <> S+ 0 0 0 -3,-1.4 4,-1.8 -4,-0.3 -1,-0.2 0.983 111.6 36.3 -64.2 -57.3 -17.1 -7.6 14.1 47 89 A P H > S+ 0 0 1 0, 0.0 4,-2.6 0, 0.0 -2,-0.2 0.804 113.1 62.1 -67.2 -22.3 -20.1 -9.5 15.5 48 90 A L H X S+ 0 0 0 -4,-2.0 4,-2.2 2,-0.2 -2,-0.2 0.935 104.4 46.5 -62.9 -45.1 -17.7 -12.4 16.3 49 91 A V H X S+ 0 0 0 -4,-2.0 4,-2.8 1,-0.2 -1,-0.2 0.912 111.7 52.2 -64.1 -38.5 -15.7 -10.2 18.7 50 92 A A H X S+ 0 0 0 -4,-1.8 4,-3.0 1,-0.2 -2,-0.2 0.913 108.0 51.5 -61.6 -44.3 -19.0 -9.0 20.2 51 93 A A H X S+ 0 0 2 -4,-2.6 4,-2.1 2,-0.2 -1,-0.2 0.921 112.3 45.4 -56.2 -48.5 -20.1 -12.6 20.7 52 94 A V H X S+ 0 0 1 -4,-2.2 4,-0.8 2,-0.2 -2,-0.2 0.897 114.4 48.1 -65.2 -41.6 -16.8 -13.4 22.5 53 95 A L H >< S+ 0 0 6 -4,-2.8 3,-0.7 1,-0.2 -2,-0.2 0.936 113.6 47.8 -62.3 -47.3 -17.0 -10.2 24.6 54 96 A H H 3< S+ 0 0 94 -4,-3.0 -2,-0.2 1,-0.2 -1,-0.2 0.865 109.0 54.1 -59.9 -39.6 -20.6 -10.9 25.6 55 97 A Q H 3< S+ 0 0 122 -4,-2.1 -1,-0.2 -5,-0.2 -2,-0.2 0.664 110.5 42.7 -74.0 -18.9 -20.0 -14.6 26.5 56 98 A N S << S- 0 0 35 -4,-0.8 5,-0.0 -3,-0.7 0, 0.0 -0.868 88.5 -91.1-132.7 156.3 -17.2 -13.9 29.0 57 99 A P > - 0 0 92 0, 0.0 3,-2.2 0, 0.0 4,-0.3 -0.328 49.7-108.4 -58.3 153.3 -16.1 -11.7 31.9 58 100 A L G > S+ 0 0 60 1,-0.3 3,-1.8 2,-0.2 4,-0.1 0.844 117.4 62.4 -57.7 -35.4 -14.0 -8.7 30.6 59 101 A T G > S+ 0 0 101 1,-0.3 3,-1.4 2,-0.2 -1,-0.3 0.489 76.4 86.3 -76.8 -0.3 -10.8 -10.2 32.0 60 102 A H G X S+ 0 0 32 -3,-2.2 3,-1.8 1,-0.2 29,-0.5 0.724 75.4 76.4 -58.3 -22.8 -11.2 -13.2 29.7 61 103 A L G < S+ 0 0 20 -3,-1.8 29,-2.6 1,-0.3 30,-0.4 0.743 87.0 58.5 -59.8 -21.3 -9.3 -10.8 27.4 62 104 A D G < S+ 0 0 114 -3,-1.4 2,-0.4 27,-0.2 -1,-0.3 0.489 78.3 115.8 -92.4 -2.1 -6.2 -11.6 29.3 63 105 A K < - 0 0 113 -3,-1.8 26,-1.8 -4,-0.1 2,-0.4 -0.530 64.6-131.0 -70.0 122.2 -6.3 -15.4 28.6 64 106 A L E -G 88 0D 97 -2,-0.4 2,-0.5 24,-0.2 24,-0.3 -0.595 19.6-161.6 -76.6 127.7 -3.4 -16.6 26.6 65 107 A I E -G 87 0D 27 22,-3.0 22,-2.5 -2,-0.4 2,-0.3 -0.941 4.0-156.3-111.1 128.2 -4.2 -18.8 23.6 66 108 A T + 0 0 111 -2,-0.5 2,-0.3 20,-0.2 17,-0.1 -0.775 17.9 164.8-104.7 152.8 -1.6 -21.0 22.0 67 109 A Y - 0 0 12 16,-0.4 2,-0.2 -2,-0.3 19,-0.1 -0.959 17.3-141.9-161.4 165.3 -1.6 -22.3 18.4 68 110 A T > - 0 0 82 -2,-0.3 3,-2.0 16,-0.0 4,-0.4 -0.581 40.2 -73.6-132.2-177.3 0.8 -23.9 15.9 69 111 A S G > S+ 0 0 106 1,-0.3 3,-1.7 2,-0.2 14,-0.0 0.855 122.9 56.4 -49.7 -44.8 1.9 -24.1 12.2 70 112 A D G 3 S+ 0 0 113 1,-0.3 -1,-0.3 3,-0.0 -3,-0.0 0.552 97.0 65.0 -75.4 -2.8 -1.2 -26.1 11.1 71 113 A D G < S+ 0 0 42 -3,-2.0 2,-1.0 1,-0.1 -1,-0.3 0.566 80.7 86.6 -88.5 -13.5 -3.5 -23.4 12.5 72 114 A I < + 0 0 60 -3,-1.7 -1,-0.1 -4,-0.4 3,-0.1 -0.771 45.7 137.2 -92.3 100.2 -2.3 -20.8 9.9 73 115 A R + 0 0 124 -2,-1.0 2,-0.3 2,-0.1 -1,-0.2 0.231 61.1 26.8-129.5 5.3 -4.5 -21.5 6.9 74 116 A S S S- 0 0 31 -3,-0.1 29,-0.2 66,-0.1 2,-0.1 -0.941 106.3 -45.4-161.2 172.2 -5.4 -18.0 5.7 75 117 A I + 0 0 143 -2,-0.3 27,-3.0 27,-0.1 28,-0.2 -0.354 61.5 161.6 -54.6 120.0 -4.3 -14.3 5.6 76 118 A S > + 0 0 9 25,-0.3 4,-2.0 26,-0.2 5,-0.2 -0.557 12.7 173.2-149.9 67.4 -3.1 -13.7 9.2 77 119 A P T 4 S+ 0 0 45 0, 0.0 4,-0.2 0, 0.0 -1,-0.1 0.792 84.6 28.4 -58.3 -33.3 -0.8 -10.6 9.4 78 120 A V T >> S+ 0 0 20 2,-0.1 3,-1.5 17,-0.1 4,-0.9 0.898 115.7 55.6 -93.5 -50.5 -0.6 -10.7 13.2 79 121 A A T 34 S+ 0 0 0 1,-0.3 4,-0.4 2,-0.2 3,-0.3 0.785 102.7 58.6 -59.8 -29.6 -1.1 -14.4 14.1 80 122 A Q T 3< S+ 0 0 103 -4,-2.0 3,-0.3 1,-0.2 -1,-0.3 0.809 106.9 48.7 -66.1 -31.0 1.9 -15.4 11.9 81 123 A Q T <4 S+ 0 0 127 -3,-1.5 -1,-0.2 -4,-0.2 -2,-0.2 0.642 115.9 41.4 -80.6 -20.9 4.2 -13.1 13.9 82 124 A H S >X S+ 0 0 55 -4,-0.9 4,-2.3 -3,-0.3 3,-1.4 0.280 77.2 110.1-114.2 8.4 3.1 -14.3 17.3 83 125 A V T 34 S+ 0 0 41 -4,-0.4 -16,-0.4 -3,-0.3 -1,-0.1 0.800 76.8 55.7 -56.7 -31.8 2.9 -18.0 16.6 84 126 A Q T 34 S+ 0 0 190 -3,-0.2 -1,-0.3 -4,-0.2 -2,-0.1 0.760 121.1 26.7 -73.4 -22.8 6.0 -18.7 18.8 85 127 A T T <4 S- 0 0 99 -3,-1.4 -2,-0.2 1,-0.2 -1,-0.2 0.610 102.7-123.8-116.3 -18.3 4.5 -17.0 21.9 86 128 A G < - 0 0 5 -4,-2.3 2,-0.3 -7,-0.1 -20,-0.2 -0.234 20.8-106.3 89.7 171.6 0.7 -17.2 21.7 87 129 A M E -G 65 0D 1 -22,-2.5 -22,-3.0 -2,-0.1 2,-0.1 -0.996 21.2-123.0-138.0 142.4 -1.9 -14.4 21.7 88 130 A T E > -G 64 0D 35 -2,-0.3 4,-2.4 -24,-0.3 -24,-0.2 -0.397 34.6-106.2 -73.9 161.6 -4.3 -13.4 24.4 89 131 A I H > S+ 0 0 0 -26,-1.8 4,-2.8 -29,-0.5 5,-0.2 0.896 124.0 52.9 -53.2 -41.7 -8.0 -13.2 23.6 90 132 A G H > S+ 0 0 12 -29,-2.6 4,-2.4 1,-0.2 -1,-0.2 0.908 108.4 48.7 -62.2 -43.6 -7.7 -9.4 23.6 91 133 A Q H > S+ 0 0 76 -30,-0.4 4,-2.5 2,-0.2 -1,-0.2 0.887 111.6 51.2 -61.8 -38.6 -4.8 -9.6 21.1 92 134 A L H X S+ 0 0 0 -4,-2.4 4,-2.9 2,-0.2 -2,-0.2 0.925 109.8 47.9 -66.2 -45.5 -6.9 -12.0 19.0 93 135 A C H X S+ 0 0 0 -4,-2.8 4,-2.2 2,-0.2 5,-0.3 0.926 112.4 50.8 -56.9 -46.6 -9.9 -9.6 19.0 94 136 A D H X S+ 0 0 34 -4,-2.4 4,-3.1 1,-0.2 5,-0.4 0.941 114.1 43.1 -56.9 -49.4 -7.6 -6.7 18.0 95 137 A A H X S+ 0 0 1 -4,-2.5 6,-1.9 1,-0.2 4,-1.8 0.886 111.1 54.6 -68.2 -40.9 -6.1 -8.6 15.1 96 138 A A H < S+ 0 0 0 -4,-2.9 4,-0.2 4,-0.3 -1,-0.2 0.904 120.4 31.7 -59.6 -41.3 -9.4 -10.0 13.9 97 139 A I H < S+ 0 0 0 -4,-2.2 112,-0.3 -5,-0.2 -2,-0.2 0.941 126.6 37.1 -80.8 -50.0 -10.9 -6.5 13.6 98 140 A R H < S+ 0 0 34 -4,-3.1 91,-1.9 -5,-0.3 92,-0.3 0.753 134.4 20.0 -84.4 -27.9 -7.9 -4.3 12.8 99 141 A Y S < S- 0 0 87 -4,-1.8 -1,-0.2 -5,-0.4 -3,-0.2 0.285 97.2-123.4-119.2 5.1 -6.0 -6.6 10.4 100 142 A S - 0 0 19 -5,-0.3 2,-0.4 -6,-0.2 -4,-0.3 0.895 39.7-167.7 48.6 46.5 -8.8 -9.0 9.5 101 143 A D > - 0 0 0 -6,-1.9 4,-1.9 1,-0.2 -25,-0.3 -0.481 15.0-160.9 -72.9 120.1 -6.6 -11.8 10.8 102 144 A G H > S+ 0 0 2 -27,-3.0 4,-2.4 -2,-0.4 38,-0.3 0.875 89.9 49.2 -74.1 -40.0 -8.1 -15.1 9.7 103 145 A T H > S+ 0 0 1 -29,-0.2 4,-2.6 -28,-0.2 5,-0.2 0.917 109.9 53.1 -63.7 -42.8 -6.3 -17.3 12.2 104 146 A A H > S+ 0 0 0 1,-0.2 4,-2.1 2,-0.2 -2,-0.2 0.919 110.8 47.0 -58.9 -42.3 -7.3 -14.9 15.0 105 147 A A H X S+ 0 0 0 -4,-1.9 4,-2.4 2,-0.2 -1,-0.2 0.906 110.6 51.7 -67.4 -40.2 -11.0 -15.2 13.9 106 148 A N H X S+ 0 0 13 -4,-2.4 4,-2.0 1,-0.2 -2,-0.2 0.898 111.1 47.8 -61.6 -39.5 -10.7 -19.0 13.6 107 149 A L H X S+ 0 0 25 -4,-2.6 4,-1.8 2,-0.2 -1,-0.2 0.855 110.4 51.9 -70.6 -34.7 -9.3 -19.2 17.2 108 150 A L H X S+ 0 0 0 -4,-2.1 4,-2.0 -5,-0.2 -2,-0.2 0.887 107.4 52.8 -67.9 -39.1 -12.1 -16.8 18.4 109 151 A L H X S+ 0 0 0 -4,-2.4 4,-2.1 1,-0.2 -2,-0.2 0.932 109.6 48.9 -57.6 -45.5 -14.7 -19.2 16.8 110 152 A A H < S+ 0 0 63 -4,-2.0 -2,-0.2 1,-0.2 -1,-0.2 0.859 107.4 55.3 -64.0 -35.2 -13.1 -22.1 18.7 111 153 A D H < S+ 0 0 43 -4,-1.8 -1,-0.2 1,-0.2 -2,-0.2 0.882 105.9 50.6 -63.4 -40.0 -13.2 -20.0 21.9 112 154 A L H < S- 0 0 31 -4,-2.0 -2,-0.2 5,-0.2 -1,-0.2 0.900 102.8-177.0 -63.4 -40.1 -17.0 -19.5 21.4 113 155 A G < + 0 0 21 -4,-2.1 8,-0.5 4,-0.2 9,-0.1 -0.040 27.3 102.4 77.9-173.6 -17.1 -23.3 21.0 114 156 A G S >> S- 0 0 55 -4,-0.1 4,-0.7 3,-0.1 3,-0.5 -0.252 76.9 -12.5 87.3-178.3 -19.9 -25.7 20.2 115 157 A P G >4>S+ 0 0 102 0, 0.0 5,-1.4 0, 0.0 3,-1.0 -0.062 123.3 27.5 -54.4 150.8 -20.7 -27.5 16.9 116 158 A G G >45S- 0 0 57 1,-0.2 3,-1.5 3,-0.2 -3,-0.0 0.764 130.4 -70.2 68.7 27.2 -19.1 -26.4 13.6 117 159 A G G <45S- 0 0 40 -3,-0.5 -1,-0.2 1,-0.3 -4,-0.2 0.739 102.9 -44.2 61.8 25.7 -16.0 -25.1 15.3 118 160 A G G 5S+ 0 0 9 -3,-1.5 4,-2.2 1,-0.2 17,-0.3 0.857 78.4 52.0 -66.2 -34.4 -20.0 -21.3 13.6 120 162 A A H > S+ 0 0 37 -6,-0.5 4,-2.1 -8,-0.5 -2,-0.2 0.854 111.1 53.9 -65.8 -35.2 -22.8 -20.5 18.3 122 164 A F H X S+ 0 0 0 -4,-2.2 4,-1.8 2,-0.2 -2,-0.2 0.943 110.0 46.2 -62.4 -47.1 -21.8 -17.4 16.2 123 165 A T H X S+ 0 0 20 -4,-2.2 4,-2.2 13,-0.2 -2,-0.2 0.900 110.3 54.5 -61.1 -40.3 -25.1 -17.8 14.2 124 166 A G H X S+ 0 0 38 -4,-2.3 4,-1.7 1,-0.2 -1,-0.2 0.855 103.6 55.4 -62.1 -36.6 -27.0 -18.2 17.5 125 167 A Y H X S+ 0 0 20 -4,-2.1 4,-0.7 2,-0.2 -1,-0.2 0.927 108.0 48.8 -62.0 -43.7 -25.5 -14.9 18.7 126 168 A L H ><>S+ 0 0 0 -4,-1.8 5,-2.2 1,-0.2 3,-1.1 0.914 108.2 53.6 -61.3 -41.0 -26.9 -13.2 15.6 127 169 A R H ><5S+ 0 0 100 -4,-2.2 3,-1.8 1,-0.3 -1,-0.2 0.852 101.9 59.5 -61.1 -34.5 -30.3 -14.8 16.1 128 170 A S H 3<5S+ 0 0 84 -4,-1.7 -1,-0.3 1,-0.3 -2,-0.2 0.718 102.7 53.2 -66.9 -22.0 -30.3 -13.4 19.7 129 171 A L T <<5S- 0 0 19 -3,-1.1 -1,-0.3 -4,-0.7 -2,-0.2 0.200 127.8-101.4 -96.5 13.8 -30.1 -10.0 18.1 130 172 A G T < 5S+ 0 0 59 -3,-1.8 2,-0.9 1,-0.2 -3,-0.2 0.567 77.2 140.4 81.0 9.3 -33.1 -10.7 16.0 131 173 A D < + 0 0 8 -5,-2.2 -1,-0.2 1,-0.1 -2,-0.1 -0.785 15.1 165.1 -86.7 103.7 -31.2 -11.5 12.8 132 174 A T + 0 0 113 -2,-0.9 -1,-0.1 -3,-0.1 -5,-0.1 0.295 68.6 59.1 -98.5 7.4 -33.1 -14.5 11.3 133 175 A V S S+ 0 0 47 -7,-0.1 21,-0.1 23,-0.1 -1,-0.1 0.853 82.6 80.3-104.5 -50.6 -31.3 -14.0 7.9 134 176 A S - 0 0 0 22,-0.1 2,-0.3 -11,-0.1 21,-0.2 -0.172 51.9-177.0 -66.6 154.7 -27.5 -14.3 8.3 135 177 A R - 0 0 81 19,-2.4 2,-0.5 16,-0.1 19,-0.3 -0.975 18.0-159.0-151.3 138.4 -25.6 -17.6 8.6 136 178 A L + 0 0 4 -17,-0.3 -13,-0.2 -2,-0.3 -14,-0.1 -0.987 21.7 159.9-114.3 127.6 -22.0 -18.7 9.2 137 179 A D + 0 0 64 -2,-0.5 2,-0.3 1,-0.2 -1,-0.1 0.573 59.6 29.2-118.1 -19.3 -21.2 -22.2 8.0 138 180 A A - 0 0 23 -19,-0.1 -1,-0.2 5,-0.0 2,-0.2 -0.897 64.8-132.7-139.8 161.6 -17.5 -22.3 7.6 139 181 A E > - 0 0 51 -2,-0.3 4,-2.0 1,-0.1 3,-0.3 -0.428 56.7 -20.1-103.6-169.1 -14.3 -20.8 9.0 140 182 A A T 4 S+ 0 0 5 -38,-0.3 -1,-0.1 1,-0.3 -66,-0.1 -0.529 122.8 11.5 -74.5 140.0 -11.3 -19.3 7.2 141 183 A P T >4 S+ 0 0 20 0, 0.0 3,-1.5 0, 0.0 -1,-0.3 -1.000 125.6 54.2 -90.2 -7.2 -10.4 -19.8 4.3 142 184 A E G >4 S+ 0 0 96 -3,-0.3 3,-2.0 1,-0.3 4,-0.3 0.785 93.0 71.0 -62.3 -30.4 -13.6 -21.6 3.2 143 185 A L G 3< S+ 0 0 2 -4,-2.0 -102,-0.4 1,-0.3 3,-0.3 0.722 97.1 51.4 -62.7 -21.1 -16.1 -18.9 4.2 144 186 A N G < S+ 0 0 30 -3,-1.5 69,-1.4 -5,-0.2 -1,-0.3 0.443 102.6 64.0 -88.3 -0.9 -14.9 -16.6 1.3 145 187 A R < + 0 0 113 -3,-2.0 -1,-0.2 -4,-0.2 -2,-0.2 0.379 60.1 126.0-112.6 -2.6 -15.2 -19.2 -1.4 146 188 A D - 0 0 13 -4,-0.3 3,-0.1 -3,-0.3 -107,-0.1 -0.308 69.1 -99.7 -60.5 144.2 -18.9 -20.2 -1.7 147 189 A P > - 0 0 57 0, 0.0 3,-2.2 0, 0.0 -1,-0.1 -0.289 49.6 -81.7 -62.4 153.2 -20.2 -19.9 -5.3 148 190 A P T 3 S+ 0 0 55 0, 0.0 3,-0.1 0, 0.0 -110,-0.1 -0.260 120.3 21.0 -49.4 133.7 -22.2 -16.8 -6.2 149 191 A G T 3 S+ 0 0 77 1,-0.3 2,-0.1 -112,-0.2 -112,-0.1 0.104 89.5 129.2 89.1 -21.7 -25.8 -17.3 -5.2 150 192 A D < - 0 0 52 -3,-2.2 -1,-0.3 1,-0.1 -4,-0.1 -0.451 54.3-145.3 -67.2 137.0 -24.9 -20.0 -2.6 151 193 A E > + 0 0 100 -2,-0.1 3,-1.0 -3,-0.1 -1,-0.1 0.643 62.7 112.3 -85.5 -11.7 -26.5 -19.1 0.8 152 194 A R T 3 S+ 0 0 110 1,-0.2 -16,-0.1 -5,-0.1 -6,-0.1 -0.309 87.0 6.0 -57.1 139.7 -23.7 -20.5 2.9 153 195 A D T 3 S+ 0 0 1 1,-0.2 -113,-2.6 -114,-0.1 -112,-0.5 0.805 102.6 136.5 60.0 36.7 -21.8 -17.9 4.8 154 196 A T E < +F 39 0C 7 -3,-1.0 -19,-2.4 -19,-0.3 -115,-0.2 -0.784 29.0 169.3-117.2 158.9 -24.1 -15.0 3.8 155 197 A T E -F 38 0C 0 -117,-2.5 -117,-2.5 -2,-0.3 3,-0.1 -0.700 29.7-119.3-136.5-168.3 -25.8 -12.0 5.3 156 198 A T > - 0 0 4 -119,-0.2 4,-2.6 -2,-0.2 5,-0.4 -0.958 24.2-114.2-132.6 157.3 -27.6 -9.1 3.7 157 199 A P H > S+ 0 0 0 0, 0.0 4,-1.9 0, 0.0 5,-0.2 0.932 120.1 49.3 -56.5 -40.7 -26.8 -5.3 3.8 158 200 A H H > S+ 0 0 48 -124,-2.6 4,-2.0 2,-0.2 5,-0.2 0.949 112.9 45.3 -58.0 -51.2 -30.1 -4.9 5.7 159 201 A A H > S+ 0 0 10 -125,-0.4 4,-1.8 1,-0.2 -1,-0.2 0.925 115.1 45.0 -64.4 -46.6 -29.4 -7.7 8.2 160 202 A I H X S+ 0 0 0 -4,-2.6 4,-2.8 1,-0.2 -1,-0.2 0.836 110.0 55.6 -73.1 -30.6 -25.8 -6.8 9.0 161 203 A A H X S+ 0 0 1 -4,-1.9 4,-2.6 -5,-0.4 -1,-0.2 0.929 108.6 47.6 -63.3 -43.9 -26.6 -3.1 9.4 162 204 A L H X S+ 0 0 63 -4,-2.0 4,-1.7 2,-0.2 -2,-0.2 0.864 112.8 49.6 -66.5 -35.2 -29.2 -3.8 12.0 163 205 A V H X S+ 0 0 2 -4,-1.8 4,-2.1 2,-0.2 -2,-0.2 0.952 112.6 46.1 -64.2 -50.8 -26.8 -6.1 13.8 164 206 A L H X S+ 0 0 2 -4,-2.8 4,-2.6 1,-0.2 5,-0.5 0.870 108.8 56.5 -64.3 -36.4 -24.0 -3.5 13.8 165 207 A Q H X>S+ 0 0 57 -4,-2.6 5,-2.2 1,-0.2 4,-2.0 0.931 109.3 46.1 -58.3 -46.3 -26.5 -0.8 14.9 166 208 A Q H <5S+ 0 0 69 -4,-1.7 6,-1.7 3,-0.2 7,-0.4 0.880 114.7 48.0 -64.5 -37.9 -27.4 -2.8 18.0 167 209 A L H <5S+ 0 0 0 -4,-2.1 6,-0.3 5,-0.2 -2,-0.2 0.897 126.4 22.4 -69.5 -44.1 -23.7 -3.6 18.8 168 210 A V H <5S+ 0 0 9 -4,-2.6 -3,-0.2 -5,-0.1 -2,-0.2 0.852 138.3 22.5 -96.9 -40.3 -22.3 -0.0 18.4 169 211 A L T <5S+ 0 0 59 -4,-2.0 -3,-0.2 -5,-0.5 -4,-0.1 0.811 118.3 51.8-100.9 -35.5 -25.3 2.3 19.0 170 212 A G S - 0 0 55 0, 0.0 4,-2.9 0, 0.0 3,-0.5 -0.379 47.1 -99.3 -65.6 156.2 -22.7 -3.4 28.2 175 217 A P H > S+ 0 0 89 0, 0.0 4,-2.4 0, 0.0 5,-0.1 0.804 120.5 51.8 -49.3 -40.1 -20.9 0.0 27.9 176 218 A D H > S+ 0 0 89 2,-0.2 4,-1.5 1,-0.2 5,-0.1 0.918 115.7 39.6 -67.1 -42.1 -17.4 -1.3 28.7 177 219 A K H > S+ 0 0 29 -3,-0.5 4,-2.2 2,-0.2 5,-0.2 0.873 113.7 56.0 -73.0 -37.4 -17.6 -4.1 26.1 178 220 A R H X S+ 0 0 53 -4,-2.9 4,-2.6 1,-0.2 -2,-0.2 0.914 107.1 50.2 -57.4 -44.9 -19.3 -1.8 23.6 179 221 A A H X S+ 0 0 47 -4,-2.4 4,-2.7 -5,-0.2 -1,-0.2 0.859 107.5 53.3 -64.1 -38.7 -16.4 0.6 23.9 180 222 A L H X S+ 0 0 46 -4,-1.5 4,-2.2 2,-0.2 -2,-0.2 0.952 112.7 43.5 -60.6 -48.8 -13.8 -2.1 23.3 181 223 A L H X S+ 0 0 0 -4,-2.2 4,-2.2 1,-0.2 5,-0.2 0.934 114.5 50.3 -63.0 -46.1 -15.5 -3.2 20.1 182 224 A T H X S+ 0 0 18 -4,-2.6 4,-2.5 1,-0.2 -1,-0.2 0.921 110.6 49.5 -57.7 -47.1 -16.0 0.4 19.0 183 225 A D H X S+ 0 0 93 -4,-2.7 4,-1.6 2,-0.2 -1,-0.2 0.879 109.4 50.6 -63.5 -39.8 -12.4 1.3 19.6 184 226 A W H < S+ 0 0 21 -4,-2.2 3,-0.2 2,-0.2 -1,-0.2 0.935 113.4 45.2 -63.8 -44.1 -11.0 -1.6 17.7 185 227 A M H >< S+ 0 0 1 -4,-2.2 22,-1.6 1,-0.2 3,-1.4 0.877 110.2 56.2 -66.3 -35.4 -13.3 -0.8 14.7 186 228 A A H 3< S+ 0 0 42 -4,-2.5 -1,-0.2 1,-0.3 -2,-0.2 0.830 110.4 44.9 -60.7 -33.2 -12.2 2.9 15.1 187 229 A R T 3< S+ 0 0 128 -4,-1.6 -1,-0.3 -3,-0.2 -2,-0.2 0.118 82.2 144.4 -99.0 16.3 -8.5 1.8 14.8 188 230 A N < - 0 0 23 -3,-1.4 -90,-0.2 19,-0.1 -89,-0.1 -0.313 34.8-163.2 -57.4 141.0 -9.1 -0.5 11.8 189 231 A T S S+ 0 0 66 -91,-1.9 3,-0.3 1,-0.1 -1,-0.1 0.478 77.6 61.4-102.6 -4.9 -6.2 -0.5 9.3 190 232 A T S S+ 0 0 42 -92,-0.3 3,-0.3 1,-0.2 -1,-0.1 0.460 87.7 68.2-105.6 -1.5 -7.9 -2.1 6.3 191 233 A G > > + 0 0 3 1,-0.2 3,-1.8 -3,-0.1 5,-0.7 0.334 55.9 108.5-108.3 5.1 -10.7 0.4 5.5 192 234 A A T 3 5S+ 0 0 69 1,-0.3 -1,-0.2 -3,-0.3 -2,-0.1 0.727 85.0 44.7 -59.8 -28.3 -9.2 3.6 4.2 193 235 A K T 3 5S+ 0 0 137 -3,-0.3 61,-0.5 3,-0.1 -1,-0.3 0.261 112.0 54.0-104.5 11.4 -10.2 3.1 0.6 194 236 A R T X>5S- 0 0 12 -3,-1.8 3,-0.7 59,-0.1 4,-0.7 0.366 122.1 -14.4-111.7-118.6 -13.8 2.0 1.2 195 237 A I H >>5S+ 0 0 0 1,-0.2 3,-1.7 2,-0.2 4,-0.6 0.913 132.9 59.5 -58.0 -41.2 -16.6 3.8 3.3 196 238 A R H >4 - 0 0 65 0, 0.0 3,-2.2 0, 0.0 -2,-0.1 -0.232 35.1-108.1 -59.4 153.1 -15.6 14.0 4.5 201 243 A A T 3 S+ 0 0 101 1,-0.3 -2,-0.0 -4,-0.1 -4,-0.0 0.757 116.2 63.0 -52.0 -31.8 -12.7 14.2 7.0 202 244 A D T 3 S+ 0 0 107 2,-0.1 2,-0.5 0, 0.0 -1,-0.3 0.495 87.5 85.7 -80.6 -0.9 -14.9 15.9 9.7 203 245 A W S < S- 0 0 17 -3,-2.2 2,-0.3 -7,-0.1 22,-0.2 -0.856 81.3-130.2 -93.3 132.9 -17.1 12.8 9.8 204 246 A K E -C 224 0A 101 20,-1.7 20,-2.3 -2,-0.5 2,-0.4 -0.665 26.7-169.1 -78.9 138.2 -15.9 10.1 12.2 205 247 A V E +C 223 0A 17 -2,-0.3 2,-0.4 18,-0.2 18,-0.2 -0.998 15.1 176.5-132.3 131.1 -15.8 6.6 10.7 206 248 A I E +C 222 0A 0 16,-2.2 16,-1.9 -2,-0.4 2,-0.3 -0.968 24.2 158.2-122.9 147.5 -15.3 3.2 12.3 207 249 A D E -C 221 0A 9 -22,-1.6 2,-0.4 -2,-0.4 14,-0.2 -0.983 39.2-141.4-160.4 168.8 -15.5 0.0 10.2 208 250 A K E -C 220 0A 0 12,-2.2 12,-2.1 -2,-0.3 2,-0.1 -0.962 27.2-156.4-140.1 124.7 -14.8 -3.6 9.4 209 251 A T E -C 219 0A 6 -2,-0.4 2,-0.3 -112,-0.3 10,-0.3 -0.408 5.7-162.7 -92.3 168.4 -14.1 -4.7 5.8 210 252 A G E -C 218 0A 0 8,-2.0 8,-3.1 -168,-0.2 2,-0.3 -0.966 6.1-178.2-149.3 146.1 -14.4 -8.0 4.0 211 253 A T E +C 217 0A 59 -2,-0.3 2,-0.2 6,-0.2 6,-0.2 -0.997 14.7 152.2-143.2 137.7 -12.8 -9.3 0.8 212 254 A G E > -C 216 0A 12 4,-1.9 4,-0.6 -2,-0.3 3,-0.3 -0.817 43.4 -59.4-148.5-171.9 -13.3 -12.6 -1.0 213 255 A D T >4 S+ 0 0 42 -69,-1.4 3,-1.1 -2,-0.2 32,-0.2 -0.119 106.1 46.9 -71.1 173.0 -13.3 -14.5 -4.2 214 256 A Y T 34 S- 0 0 44 30,-2.2 25,-2.7 1,-0.2 -1,-0.2 0.824 136.2 -65.6 56.7 34.8 -15.6 -13.7 -7.2 215 257 A G T 34 S+ 0 0 0 31,-1.2 34,-0.5 29,-0.4 2,-0.3 0.761 82.8 174.2 63.6 27.9 -14.5 -10.0 -6.7 216 258 A R E << +C 212 0A 14 -3,-1.1 -4,-1.9 -4,-0.6 2,-0.3 -0.493 7.0 165.3 -71.5 127.7 -16.2 -9.7 -3.3 217 259 A A E +CD 211 237A 0 20,-1.8 20,-0.7 -2,-0.3 2,-0.3 -0.939 5.8 167.9-145.5 124.2 -15.6 -6.5 -1.4 218 260 A N E -CD 210 236A 1 -8,-3.1 -8,-2.0 -2,-0.3 2,-0.3 -0.882 13.1-175.3-128.8 160.9 -17.6 -5.4 1.6 219 261 A D E -CD 209 235A 0 16,-2.8 16,-2.7 -2,-0.3 2,-0.4 -0.922 4.6-168.0-157.2 133.1 -17.5 -2.7 4.3 220 262 A I E +CD 208 234A 1 -12,-2.1 -12,-2.2 -2,-0.3 2,-0.3 -0.987 23.3 167.2-121.7 133.8 -19.7 -2.1 7.3 221 263 A A E -CD 207 233A 0 12,-2.7 12,-2.7 -2,-0.4 2,-0.4 -0.945 36.8-141.9-142.5 157.9 -19.4 1.1 9.2 222 264 A V E -CD 206 232A 0 -16,-1.9 -16,-2.2 -2,-0.3 2,-0.3 -0.997 30.3-170.4-116.4 130.3 -20.8 3.5 11.8 223 265 A V E -CD 205 231A 0 8,-3.0 8,-2.8 -2,-0.4 2,-0.4 -0.895 10.3-154.2-119.0 150.7 -20.3 7.1 10.9 224 266 A W E -CD 204 230A 49 -20,-2.3 -20,-1.7 -2,-0.3 -2,-0.0 -0.994 16.2-130.4-126.2 131.8 -20.9 10.2 12.9 225 267 A S > - 0 0 15 4,-2.5 3,-2.2 -2,-0.4 -21,-0.2 -0.184 38.8 -96.6 -66.0 166.6 -21.7 13.6 11.5 226 268 A P T 3 S+ 0 0 75 0, 0.0 -1,-0.1 0, 0.0 -23,-0.1 0.699 128.9 51.3 -61.7 -16.6 -19.6 16.7 12.7 227 269 A T T 3 S- 0 0 128 2,-0.1 -2,-0.1 0, 0.0 -24,-0.1 0.212 126.2-100.0-102.2 12.9 -22.5 17.3 15.2 228 270 A G S < S+ 0 0 47 -3,-2.2 -25,-0.0 1,-0.2 -4,-0.0 0.728 71.2 146.7 82.1 24.3 -22.5 13.8 16.5 229 271 A V - 0 0 58 2,-0.0 -4,-2.5 0, 0.0 -1,-0.2 -0.836 38.1-145.2 -93.3 118.6 -25.4 12.3 14.6 230 272 A P E - D 0 224A 37 0, 0.0 2,-0.3 0, 0.0 -6,-0.2 -0.606 19.8-179.5 -92.4 149.1 -24.7 8.6 13.9 231 273 A Y E - D 0 223A 24 -8,-2.8 -8,-3.0 -2,-0.2 2,-0.4 -0.986 22.1-135.0-136.8 149.0 -25.6 6.5 10.9 232 274 A V E - D 0 222A 4 -2,-0.3 2,-0.5 -10,-0.2 -10,-0.2 -0.888 22.3-168.3-104.1 134.4 -24.9 2.8 10.1 233 275 A V E - D 0 221A 0 -12,-2.7 -12,-2.7 -2,-0.4 2,-0.5 -0.979 7.9-177.7-130.7 117.7 -23.6 2.1 6.5 234 276 A A E +AD 20 220A 0 -214,-2.5 -214,-2.2 -2,-0.5 2,-0.4 -0.977 5.0 175.4-117.1 122.0 -23.4 -1.4 5.0 235 277 A V E +AD 19 219A 0 -16,-2.7 -16,-2.8 -2,-0.5 2,-0.3 -0.997 3.4 174.3-127.3 128.3 -22.0 -1.7 1.5 236 278 A M E +AD 18 218A 0 -218,-2.6 -218,-2.9 -2,-0.4 2,-0.3 -0.968 3.9 170.3-133.3 146.2 -21.5 -5.2 -0.1 237 279 A S E -AD 17 217A 1 -20,-0.7 -20,-1.8 -2,-0.3 2,-0.3 -0.997 13.0-177.0-153.0 155.0 -20.4 -6.1 -3.6 238 280 A D E -A 16 0A 12 -222,-1.9 -222,-2.5 -2,-0.3 -23,-0.2 -0.973 20.6-150.5-145.5 166.1 -19.3 -8.9 -5.9 239 281 A R > + 0 0 39 -25,-2.7 3,-2.5 -2,-0.3 4,-0.1 -0.461 30.5 159.7-129.2 58.9 -18.2 -9.3 -9.5 240 282 A A G > + 0 0 34 1,-0.3 3,-2.0 2,-0.2 -1,-0.1 0.737 64.6 73.9 -59.6 -25.7 -19.4 -12.8 -10.2 241 283 A G G 3 S+ 0 0 66 -227,-0.4 -1,-0.3 1,-0.3 3,-0.1 0.693 93.9 54.5 -59.1 -22.3 -19.3 -12.2 -14.0 242 284 A G G < S- 0 0 39 -3,-2.5 3,-0.4 1,-0.3 -1,-0.3 0.354 107.8-133.1 -91.8 5.3 -15.4 -12.4 -13.8 243 285 A G X - 0 0 26 -3,-2.0 3,-2.0 1,-0.2 -1,-0.3 -0.146 51.0 -32.9 71.6-168.8 -15.5 -15.8 -12.1 244 286 A Y T 3 S+ 0 0 101 1,-0.3 -30,-2.2 -30,-0.2 -29,-0.4 0.805 138.7 47.0 -54.9 -39.5 -13.5 -17.0 -9.0 245 287 A D T 3 S+ 0 0 130 -3,-0.4 -1,-0.3 -32,-0.2 -2,-0.1 0.283 77.1 138.8 -92.8 10.2 -10.5 -14.8 -9.7 246 288 A A < - 0 0 12 -3,-2.0 -31,-1.2 1,-0.1 -30,-0.2 -0.292 60.4-110.6 -53.5 136.1 -12.4 -11.6 -10.4 247 289 A E - 0 0 135 -33,-0.1 -1,-0.1 -32,-0.1 2,-0.1 -0.548 24.9-122.7 -72.8 129.4 -10.6 -8.6 -8.8 248 290 A P - 0 0 37 0, 0.0 2,-0.6 0, 0.0 -32,-0.2 -0.471 24.7-145.6 -63.6 145.3 -12.3 -7.0 -5.8 249 291 A R >> - 0 0 98 -34,-0.5 3,-1.3 1,-0.1 4,-0.7 -0.814 20.8-178.8-125.0 92.8 -12.9 -3.3 -6.6 250 292 A E H >> S+ 0 0 58 -2,-0.6 4,-2.1 1,-0.3 3,-0.7 0.800 80.0 68.9 -54.4 -34.5 -12.6 -1.0 -3.5 251 293 A A H 3> S+ 0 0 42 1,-0.3 4,-2.8 2,-0.2 -1,-0.3 0.823 91.5 60.6 -60.9 -31.2 -13.4 2.1 -5.7 252 294 A L H <> S+ 0 0 0 -3,-1.3 4,-2.5 2,-0.2 -1,-0.3 0.909 107.3 45.0 -58.6 -43.6 -16.9 0.8 -6.1 253 295 A L H X S+ 0 0 0 -4,-2.1 4,-2.1 1,-0.2 3,-0.6 0.938 110.1 52.6 -63.1 -47.3 -24.6 7.9 0.5 261 303 A A H 3X S+ 0 0 7 -4,-3.1 4,-1.7 1,-0.2 -2,-0.2 0.840 103.6 58.2 -58.6 -37.2 -22.6 10.8 2.2 262 304 A G H 3< S+ 0 0 57 -4,-1.9 -1,-0.2 1,-0.2 -2,-0.2 0.863 110.1 43.2 -58.5 -38.8 -24.1 13.3 -0.2 263 305 A V H << S+ 0 0 81 -4,-1.2 -2,-0.2 -3,-0.6 -1,-0.2 0.861 114.8 48.9 -76.1 -38.1 -27.6 12.3 0.9 264 306 A L H < 0 0 12 -4,-2.1 -2,-0.2 -5,-0.1 -1,-0.2 0.711 360.0 360.0 -78.3 -20.6 -26.7 12.3 4.6 265 307 A A < 0 0 102 -4,-1.7 -3,-0.0 -5,-0.2 -40,-0.0 -0.202 360.0 360.0 -67.6 360.0 -24.9 15.7 4.6