==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER TRANSCRIPTION 02-MAY-07 2PQW . COMPND 2 MOLECULE: LETHAL(3)MALIGNANT BRAIN TUMOR-LIKE PROTEIN; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR A.ALLALI-HASSANI,Y.LIU,N.HERZANYCH,H.OUYANG,F.MACKENZIE,L.CR . 324 2 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 17654.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 178 54.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 14 4.3 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 65 20.1 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 4 1.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 17 5.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 41 12.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 29 9.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 6 1.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 3 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 4 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 3 1 3 2 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 206 A W 0 0 157 0, 0.0 2,-0.3 0, 0.0 3,-0.1 0.000 360.0 360.0 360.0 128.3 -22.6 70.1 -20.2 2 207 A S > - 0 0 36 1,-0.1 4,-2.1 0, 0.0 5,-0.1 -0.983 360.0-130.4-136.9 150.1 -22.3 73.7 -19.0 3 208 A W H > S+ 0 0 19 -2,-0.3 4,-3.6 1,-0.2 5,-0.3 0.934 109.3 56.4 -57.4 -46.7 -23.9 75.6 -16.0 4 209 A E H > S+ 0 0 141 2,-0.2 4,-1.1 1,-0.2 -1,-0.2 0.839 110.2 42.3 -53.6 -49.0 -24.9 78.4 -18.5 5 210 A S H > S+ 0 0 62 2,-0.2 4,-2.3 1,-0.2 -1,-0.2 0.904 117.1 47.7 -66.1 -45.7 -26.9 76.1 -20.7 6 211 A Y H X S+ 0 0 21 -4,-2.1 4,-2.8 2,-0.2 5,-0.3 0.954 111.4 47.9 -63.9 -54.2 -28.4 74.3 -17.8 7 212 A L H X>S+ 0 0 34 -4,-3.6 5,-1.2 1,-0.2 4,-0.6 0.771 114.1 52.5 -53.4 -31.0 -29.4 77.5 -15.9 8 213 A E H <5S+ 0 0 155 -4,-1.1 -2,-0.2 -5,-0.3 -1,-0.2 0.908 112.9 41.5 -67.3 -45.8 -30.9 78.5 -19.4 9 214 A E H <5S+ 0 0 129 -4,-2.3 -2,-0.2 1,-0.2 -3,-0.2 0.775 120.4 43.1 -74.6 -28.5 -32.9 75.3 -19.8 10 215 A Q H <5S- 0 0 106 -4,-2.8 -1,-0.2 -5,-0.2 -2,-0.2 0.517 99.9-134.2 -99.9 0.2 -34.1 75.3 -16.2 11 216 A K T <5 + 0 0 192 -4,-0.6 -3,-0.2 -5,-0.3 2,-0.1 0.806 64.3 131.5 48.0 35.9 -34.8 79.1 -16.1 12 217 A A < - 0 0 27 -5,-1.2 2,-0.3 -6,-0.2 -1,-0.2 -0.412 52.1-129.4-114.6 178.1 -32.9 79.1 -12.8 13 218 A I - 0 0 99 234,-0.4 236,-2.9 -2,-0.1 2,-0.3 -0.952 15.2-127.5-130.6 150.3 -30.2 80.9 -10.8 14 219 A T B -a 249 0A 39 -2,-0.3 236,-0.2 234,-0.3 234,-0.1 -0.634 42.2 -98.2 -82.1 148.5 -27.1 79.8 -9.0 15 220 A A - 0 0 2 234,-2.7 284,-0.4 -2,-0.3 2,-0.1 -0.576 53.4-105.7 -51.5 124.8 -26.8 81.1 -5.4 16 221 A P > - 0 0 57 0, 0.0 3,-2.9 0, 0.0 4,-0.4 -0.387 19.5-118.6 -60.5 137.9 -24.5 84.1 -5.8 17 222 A V G > S+ 0 0 88 1,-0.3 3,-1.4 2,-0.2 8,-0.1 0.788 111.8 68.4 -41.1 -34.2 -20.8 83.6 -4.6 18 223 A S G 3 S+ 0 0 109 1,-0.3 -1,-0.3 7,-0.0 4,-0.1 0.613 89.5 62.7 -73.1 -10.8 -21.5 86.4 -2.1 19 224 A L G < S+ 0 0 41 -3,-2.9 -1,-0.3 2,-0.1 224,-0.2 0.654 95.1 76.6 -82.2 -19.3 -23.9 84.2 -0.1 20 225 A F S < S- 0 0 11 -3,-1.4 2,-0.1 -4,-0.4 272,-0.1 -0.518 90.5-102.7 -89.4 158.7 -21.1 81.7 0.7 21 226 A Q >> - 0 0 112 270,-0.3 4,-1.5 -2,-0.2 3,-0.9 -0.492 37.5-111.4 -69.2 150.3 -18.3 81.9 3.2 22 227 A D H 3> S+ 0 0 147 1,-0.2 4,-2.6 2,-0.2 3,-0.2 0.872 119.0 55.0 -48.0 -44.2 -14.9 82.8 1.7 23 228 A S H 34 S+ 0 0 69 1,-0.2 -1,-0.2 2,-0.2 58,-0.1 0.793 108.0 48.0 -66.0 -29.0 -13.6 79.3 2.5 24 229 A Q H <4 S+ 0 0 2 -3,-0.9 -1,-0.2 1,-0.1 -2,-0.2 0.794 119.5 40.0 -76.3 -29.0 -16.6 77.7 0.6 25 230 A A H < S+ 0 0 19 -4,-1.5 -2,-0.2 -3,-0.2 -3,-0.2 0.785 81.9 113.0 -92.2 -34.0 -16.0 79.9 -2.4 26 231 A V < + 0 0 30 -4,-2.6 -5,-0.0 -5,-0.2 -4,-0.0 -0.174 24.8 158.0 -58.5 127.1 -12.2 80.2 -2.8 27 232 A T + 0 0 38 1,-0.0 -1,-0.1 277,-0.0 -4,-0.0 0.548 56.9 76.0-120.4 -15.5 -11.0 78.6 -6.1 28 233 A H + 0 0 145 2,-0.1 2,-0.4 277,-0.0 -2,-0.1 0.479 69.2 102.4 -87.5 -1.7 -7.6 80.2 -6.7 29 234 A N S S- 0 0 63 1,-0.0 2,-0.1 32,-0.0 51,-0.1 -0.670 70.7-128.5 -82.4 130.2 -5.6 78.3 -4.0 30 235 A K - 0 0 173 -2,-0.4 2,-0.9 1,-0.1 -2,-0.1 -0.484 17.1-122.1 -73.5 145.6 -3.4 75.5 -5.3 31 236 A N + 0 0 27 1,-0.1 31,-0.1 -2,-0.1 -1,-0.1 -0.855 31.0 178.4 -87.1 105.1 -3.7 72.1 -3.6 32 237 A G + 0 0 24 -2,-0.9 2,-0.2 95,-0.1 -1,-0.1 0.402 41.3 115.4 -88.4 0.3 -0.2 71.4 -2.4 33 238 A F - 0 0 4 94,-0.1 2,-0.3 90,-0.1 -2,-0.1 -0.544 48.6-163.9 -70.9 137.0 -1.1 68.1 -0.8 34 239 A K > - 0 0 122 -2,-0.2 3,-2.0 1,-0.1 21,-0.3 -0.904 29.7 -83.1-124.5 149.8 0.6 65.1 -2.4 35 240 A L T 3 S+ 0 0 126 -2,-0.3 21,-0.2 1,-0.2 -1,-0.1 -0.184 113.3 16.0 -46.6 131.6 0.1 61.3 -2.3 36 241 A G T 3 S+ 0 0 36 19,-3.0 85,-0.4 1,-0.3 -1,-0.2 0.334 84.8 143.7 84.7 -10.2 1.6 59.7 0.8 37 242 A M < - 0 0 9 -3,-2.0 18,-2.7 83,-0.1 2,-0.3 -0.407 41.7-139.4 -60.0 139.9 2.1 62.9 2.8 38 243 A K E +Gh 54 122B 19 83,-2.3 85,-2.8 16,-0.2 50,-0.4 -0.771 33.1 144.8-106.5 151.2 1.6 62.3 6.6 39 244 A L E -G 53 0B 0 14,-2.3 14,-2.7 -2,-0.3 2,-0.3 -0.911 42.8 -96.0-163.5-177.5 -0.2 64.7 9.0 40 245 A E E +GI 52 86B 0 46,-2.8 46,-3.2 -2,-0.3 2,-0.3 -0.910 43.4 162.1-116.5 147.2 -2.5 64.9 12.1 41 246 A G E -GI 51 85B 0 10,-2.0 10,-2.4 -2,-0.3 44,-0.2 -0.998 39.7 -91.7-162.6 160.1 -6.3 65.3 12.0 42 247 A I E -G 50 0B 11 42,-2.3 8,-0.2 -2,-0.3 6,-0.1 -0.454 39.5-121.8 -69.8 139.6 -9.6 65.0 13.8 43 248 A D E > -G 46 0B 16 6,-2.0 3,-1.1 3,-0.7 6,-0.3 -0.778 17.2-143.7 -78.3 117.2 -11.5 61.8 13.4 44 249 A P T 3 S+ 0 0 64 0, 0.0 -1,-0.1 0, 0.0 -2,-0.0 0.767 101.1 49.0 -55.8 -23.7 -14.9 62.9 11.9 45 250 A Q T 3 S+ 0 0 140 1,-0.3 -2,-0.0 2,-0.0 -3,-0.0 0.696 122.6 31.7 -86.7 -20.2 -16.6 60.2 14.0 46 251 A H E X S-G 43 0B 70 -3,-1.1 3,-2.5 3,-0.2 -3,-0.7 -0.731 74.7-173.5-135.7 77.1 -14.9 61.2 17.2 47 252 A P E 3 S+ 0 0 21 0, 0.0 133,-0.1 0, 0.0 -1,-0.1 0.513 80.0 57.5 -62.2 -6.8 -14.4 65.0 16.9 48 253 A S E 3 S+ 0 0 31 131,-0.1 2,-0.3 -6,-0.1 132,-0.0 0.532 94.4 83.9 -90.7 -12.7 -12.3 65.3 20.1 49 254 A M E < - 0 0 56 -3,-2.5 -6,-2.0 -6,-0.3 2,-0.4 -0.775 62.1-151.1-105.1 144.0 -9.7 62.8 19.0 50 255 A Y E +Gj 42 98B 3 47,-0.8 49,-3.5 -2,-0.3 2,-0.3 -0.907 17.1 179.6-116.9 139.3 -6.6 63.3 16.8 51 256 A F E -Gj 41 99B 24 -10,-2.4 -10,-2.0 -2,-0.4 2,-0.5 -0.841 36.6 -98.2-133.0 155.9 -5.0 60.6 14.6 52 257 A I E -G 40 0B 4 47,-0.8 16,-1.6 -2,-0.3 2,-0.3 -0.752 47.8-172.2 -75.1 127.7 -2.1 60.1 12.2 53 258 A L E -GK 39 67B 0 -14,-2.7 -14,-2.3 -2,-0.5 2,-0.4 -0.898 13.4-156.1-127.8 146.3 -3.5 60.5 8.6 54 259 A T E -GK 38 66B 18 12,-1.9 12,-2.2 -2,-0.3 2,-0.6 -0.974 29.8-109.2-125.1 136.7 -1.9 59.9 5.2 55 260 A V E + K 0 65B 3 -18,-2.7 -19,-3.0 -2,-0.4 10,-0.2 -0.571 40.0 170.9 -63.1 113.4 -2.9 61.5 1.9 56 261 A A E - 0 0 36 8,-3.3 2,-0.3 -2,-0.6 9,-0.2 0.685 63.7 -0.5 -97.5 -26.1 -4.5 58.5 -0.1 57 262 A E E - K 0 64B 74 7,-1.2 7,-2.9 -23,-0.1 2,-0.4 -0.974 57.8-151.8-162.0 149.9 -5.9 60.4 -3.1 58 263 A V E + K 0 63B 52 -2,-0.3 2,-0.3 5,-0.2 5,-0.2 -0.999 12.7 175.8-130.2 133.0 -6.2 64.0 -4.3 59 264 A C E > - K 0 62B 31 3,-2.3 3,-2.0 -2,-0.4 248,-0.1 -0.889 61.8 -58.8-136.9 111.1 -8.9 65.4 -6.5 60 265 A G T 3 S- 0 0 22 246,-0.4 246,-0.2 -2,-0.3 -1,-0.1 -0.380 121.8 -13.4 53.6-126.3 -8.8 69.1 -7.4 61 266 A Y T 3 S+ 0 0 13 -3,-0.1 19,-2.8 241,-0.1 20,-0.3 0.230 126.0 84.1 -87.0 14.1 -9.0 71.1 -4.1 62 267 A R E < -KL 59 79B 1 -3,-2.0 -3,-2.3 17,-0.3 2,-0.3 -0.805 57.2-163.5-118.5 155.6 -10.0 68.0 -2.1 63 268 A L E -KL 58 78B 0 15,-2.7 15,-2.2 -2,-0.3 2,-0.5 -0.994 17.3-133.1-140.5 145.5 -8.0 65.1 -0.6 64 269 A R E -KL 57 77B 67 -7,-2.9 -8,-3.3 -2,-0.3 -7,-1.2 -0.886 25.7-156.4 -96.5 125.5 -8.8 61.6 0.7 65 270 A L E -KL 55 76B 0 11,-3.3 11,-1.8 -2,-0.5 2,-0.4 -0.855 3.1-157.9-107.5 141.7 -7.2 60.8 4.1 66 271 A H E -K 54 0B 44 -12,-2.2 -12,-1.9 -2,-0.4 2,-0.8 -0.936 20.5-123.5-120.7 136.8 -6.5 57.4 5.5 67 272 A F E > -K 53 0B 9 -2,-0.4 3,-2.4 4,-0.3 -14,-0.2 -0.711 35.7-119.5 -83.7 111.0 -6.0 56.4 9.1 68 273 A D T 3 S+ 0 0 9 -16,-1.6 34,-1.1 -2,-0.8 -16,-0.2 -0.238 95.2 10.2 -50.5 127.6 -2.6 54.8 9.5 69 274 A G T 3 S+ 0 0 48 1,-0.3 -1,-0.3 32,-0.2 2,-0.2 0.161 113.1 96.1 87.7 -16.4 -2.9 51.2 10.7 70 275 A Y S < S- 0 0 77 -3,-2.4 -1,-0.3 1,-0.1 2,-0.1 -0.470 84.2 -74.9-103.6 174.9 -6.6 51.1 10.2 71 276 A S > - 0 0 50 -2,-0.2 3,-1.7 1,-0.1 -4,-0.3 -0.379 32.6-125.7 -71.0 147.0 -8.9 49.9 7.5 72 277 A E G > S+ 0 0 141 1,-0.3 3,-1.3 2,-0.2 -1,-0.1 0.568 102.9 79.5 -65.7 -11.1 -9.4 51.8 4.3 73 278 A C G 3 S+ 0 0 100 1,-0.2 -1,-0.3 -7,-0.0 -2,-0.0 0.664 87.2 59.3 -74.0 -12.2 -13.2 51.8 4.9 74 279 A H G < S+ 0 0 102 -3,-1.7 -1,-0.2 -7,-0.1 -2,-0.2 0.453 77.3 125.5 -90.8 -1.2 -12.6 54.7 7.4 75 280 A D < - 0 0 30 -3,-1.3 2,-0.3 -4,-0.1 -9,-0.2 -0.192 39.0-173.6 -58.2 147.6 -11.0 57.0 4.7 76 281 A F E -L 65 0B 30 -11,-1.8 -11,-3.3 182,-0.0 2,-0.4 -0.977 19.5-122.1-144.0 157.5 -12.7 60.4 4.4 77 282 A W E +L 64 0B 32 -2,-0.3 2,-0.3 -13,-0.2 -13,-0.2 -0.811 28.8 167.9-100.5 142.7 -12.5 63.5 2.2 78 283 A V E -L 63 0B 17 -15,-2.2 -15,-2.7 -2,-0.4 2,-0.2 -0.893 37.3-102.5-136.7 167.9 -11.7 67.1 3.3 79 284 A N E > -L 62 0B 6 -2,-0.3 3,-1.9 -17,-0.2 -17,-0.3 -0.546 33.7-112.9 -83.8 160.7 -10.9 70.2 1.4 80 285 A A T 3 S+ 0 0 6 -19,-2.8 49,-0.2 1,-0.3 -18,-0.1 0.719 118.8 56.4 -71.3 -19.8 -7.3 71.4 1.3 81 286 A N T 3 S+ 0 0 23 -20,-0.3 -1,-0.3 -58,-0.1 -19,-0.1 0.127 78.3 142.2 -92.7 20.8 -8.3 74.4 3.4 82 287 A S < - 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