==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=11-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER SIGNALING PROTEIN 20-JUN-99 1QSC . COMPND 2 MOLECULE: TNF RECEPTOR ASSOCIATED FACTOR 2; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR S.M.MCWHIRTER,S.S.PULLEN,J.M.HOLTON,J.J.CRUTE,M.R.KEHRY, . 555 6 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 25689.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 371 66.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 144 25.9 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 3 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 3 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 50 9.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 60 10.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 92 16.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 3 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 1 0 2 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 6 9 0 0 9 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 3 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 323 A Q > 0 0 118 0, 0.0 4,-3.1 0, 0.0 5,-0.2 0.000 360.0 360.0 360.0 -33.9 46.5 32.9 48.4 2 324 A L H > + 0 0 61 2,-0.2 4,-2.2 1,-0.2 5,-0.3 0.926 360.0 44.6 -69.6 -47.2 47.2 36.6 49.3 3 325 A E H 4 S+ 0 0 91 1,-0.2 4,-0.3 2,-0.2 -1,-0.2 0.761 118.3 48.4 -67.6 -25.1 49.3 37.2 46.2 4 326 A R H > S+ 0 0 66 2,-0.2 4,-2.1 3,-0.1 -2,-0.2 0.933 113.3 42.4 -79.6 -52.1 46.6 35.4 44.2 5 327 A S H X S+ 0 0 34 -4,-3.1 4,-1.8 1,-0.2 -2,-0.2 0.958 118.0 45.2 -60.2 -53.8 43.5 37.1 45.6 6 328 A I H X S+ 0 0 36 -4,-2.2 4,-0.7 -5,-0.2 -1,-0.2 0.732 111.2 58.6 -63.0 -22.8 45.1 40.6 45.5 7 329 A G H >> S+ 0 0 37 -4,-0.3 4,-0.7 -5,-0.3 3,-0.6 0.951 105.5 43.4 -72.7 -51.7 46.4 39.8 42.0 8 330 A L H >X S+ 0 0 63 -4,-2.1 3,-1.8 1,-0.2 4,-1.6 0.936 107.2 60.2 -59.7 -49.9 43.0 39.0 40.3 9 331 A K H 3X S+ 0 0 43 -4,-1.8 4,-1.7 1,-0.3 -1,-0.2 0.777 97.3 61.8 -49.9 -31.6 41.2 42.0 41.8 10 332 A D H X S+ 0 0 93 -4,-2.2 4,-3.5 2,-0.2 3,-0.7 0.976 113.4 44.8 -63.5 -57.4 38.6 46.8 33.5 16 338 A L H 3X S+ 0 0 2 -4,-2.6 4,-2.5 1,-0.3 5,-0.2 0.906 113.3 51.1 -54.8 -43.9 36.1 48.7 35.6 17 339 A E H 3X S+ 0 0 91 -4,-3.8 4,-0.8 1,-0.2 -1,-0.3 0.796 113.9 47.4 -64.2 -26.1 38.4 51.8 35.6 18 340 A Q H X S+ 0 0 62 -4,-2.6 3,-2.7 1,-0.2 4,-1.8 0.971 107.0 55.4 -68.7 -55.6 35.1 54.8 28.1 23 345 A X H 3< S+ 0 0 32 -4,-2.7 -1,-0.2 1,-0.3 -2,-0.2 0.820 102.5 56.1 -46.7 -42.4 31.6 55.9 29.3 24 346 A E T 3< S+ 0 0 65 -4,-1.3 -1,-0.3 1,-0.2 -2,-0.2 0.575 113.2 42.0 -72.3 -6.7 32.8 59.4 30.0 25 347 A A T <4 S+ 0 0 22 -3,-2.7 8,-0.2 -4,-0.2 -2,-0.2 0.686 89.4 104.9-107.2 -29.1 34.0 59.8 26.4 26 348 A S < - 0 0 11 -4,-1.8 2,-0.3 33,-0.1 33,-0.2 -0.237 46.9-172.0 -59.4 137.9 31.1 58.2 24.5 27 349 A T - 0 0 2 31,-0.1 33,-2.6 35,-0.0 35,-0.2 -0.803 16.3-153.7-122.9 167.6 28.7 60.4 22.7 28 350 A Y S S+ 0 0 76 -2,-0.3 35,-0.2 31,-0.2 36,-0.1 0.177 76.9 73.7-132.4 19.3 25.4 59.4 21.0 29 351 A D S S- 0 0 88 2,-0.3 32,-0.2 33,-0.1 147,-0.1 0.208 106.3-103.5-116.6 13.2 24.8 61.9 18.2 30 352 A G S S+ 0 0 0 30,-2.1 144,-2.5 1,-0.2 2,-0.5 0.418 89.6 111.3 82.9 -4.6 27.4 60.7 15.8 31 353 A V E +A 173 0A 46 142,-0.2 2,-0.4 29,-0.2 -2,-0.3 -0.915 43.2 178.9-108.3 126.0 29.8 63.6 16.6 32 354 A F E -A 172 0A 2 140,-2.8 140,-2.8 -2,-0.5 2,-0.5 -0.980 17.7-166.2-131.4 137.2 33.0 62.7 18.4 33 355 A I E -A 171 0A 21 -2,-0.4 2,-0.5 138,-0.2 138,-0.2 -0.982 12.4-163.7-123.8 117.1 35.9 64.8 19.5 34 356 A W E -A 170 0A 21 136,-3.8 136,-2.9 -2,-0.5 2,-0.6 -0.899 3.1-157.5-104.7 120.9 39.0 62.8 20.5 35 357 A K E -A 169 0A 81 -2,-0.5 2,-0.7 134,-0.2 134,-0.2 -0.891 3.6-164.2-101.8 122.6 41.7 64.6 22.5 36 358 A I E -A 168 0A 4 132,-2.7 132,-1.9 -2,-0.6 3,-0.3 -0.914 13.2-175.4-109.8 107.1 45.1 63.0 22.3 37 359 A S E +A 167 0A 54 -2,-0.7 130,-0.2 130,-0.2 5,-0.1 -0.441 62.4 39.2 -94.0 170.7 47.4 64.3 25.1 38 360 A D S > S+ 0 0 52 128,-0.7 4,-2.1 127,-0.3 -1,-0.2 0.911 72.8 166.9 54.4 43.0 51.1 63.6 25.6 39 361 A F H > + 0 0 8 127,-2.1 4,-3.8 -3,-0.3 5,-0.3 0.917 62.3 58.1 -53.9 -55.2 51.4 63.9 21.9 40 362 A A H > S+ 0 0 55 1,-0.2 4,-2.1 2,-0.2 -1,-0.2 0.891 111.3 41.8 -45.4 -51.8 55.2 64.1 21.7 41 363 A R H > S+ 0 0 173 2,-0.2 4,-2.9 1,-0.2 -1,-0.2 0.934 116.2 47.8 -64.5 -48.1 55.7 60.7 23.5 42 364 A K H X S+ 0 0 70 -4,-2.1 4,-1.1 1,-0.2 -2,-0.2 0.910 111.4 51.9 -59.6 -42.7 52.9 59.0 21.6 43 365 A R H X S+ 0 0 47 -4,-3.8 4,-1.9 1,-0.2 3,-0.4 0.907 111.6 47.6 -59.0 -42.8 54.3 60.4 18.3 44 366 A Q H X S+ 0 0 99 -4,-2.1 4,-3.4 -5,-0.3 5,-0.3 0.927 105.7 56.2 -66.0 -45.9 57.7 59.0 19.3 45 367 A E H <>S+ 0 0 50 -4,-2.9 6,-2.6 1,-0.2 5,-1.0 0.734 110.5 48.1 -59.3 -21.6 56.4 55.5 20.3 46 368 A A H <5S+ 0 0 9 -4,-1.1 3,-0.3 -3,-0.4 -1,-0.2 0.867 111.9 45.8 -86.0 -41.5 54.9 55.4 16.7 47 369 A V H <5S+ 0 0 68 -4,-1.9 -2,-0.2 1,-0.2 -3,-0.2 0.932 112.7 52.1 -64.6 -44.0 58.1 56.5 14.9 48 370 A A T <5S- 0 0 52 -4,-3.4 -1,-0.2 -5,-0.2 -2,-0.2 0.673 112.2-126.7 -65.4 -18.1 60.0 54.0 17.1 49 371 A G T 5S+ 0 0 42 -3,-0.3 -3,-0.2 -5,-0.3 -4,-0.1 0.526 80.1 112.2 84.3 5.0 57.6 51.4 16.1 50 372 A R S S- 0 0 52 4,-0.4 3,-2.0 -35,-0.2 -1,-0.3 -0.942 88.2 -80.1-167.1 169.6 22.3 57.1 18.7 63 385 A R T 3 S+ 0 0 50 1,-0.3 -34,-0.1 -2,-0.3 -1,-0.0 0.831 133.2 19.2 -50.9 -38.2 21.6 55.7 22.1 64 386 A Y T 3 S+ 0 0 32 -36,-0.1 -1,-0.3 31,-0.0 35,-0.1 -0.095 110.3 104.6-124.1 34.6 21.1 52.2 20.7 65 387 A G S < S- 0 0 2 -3,-2.0 31,-0.4 1,-0.3 2,-0.1 0.091 78.1 -36.4 -95.6-153.0 22.8 52.7 17.3 66 388 A Y - 0 0 2 28,-0.1 -5,-1.2 29,-0.1 2,-0.5 -0.393 53.4-134.6 -70.3 147.8 26.1 51.6 15.8 67 389 A K E +FG 60 92B 44 25,-0.6 25,-2.4 -7,-0.2 2,-0.3 -0.887 35.8 164.6-104.1 133.4 29.1 51.5 18.0 68 390 A X E +FG 59 91B 0 -9,-2.7 -9,-2.8 -2,-0.5 2,-0.3 -0.933 17.6 178.3-144.9 165.9 32.3 53.0 16.5 69 391 A C E - G 0 90B 2 21,-1.8 21,-2.6 -2,-0.3 2,-0.3 -0.935 25.7-115.0-156.7 174.0 35.7 54.3 17.3 70 392 A L E - G 0 89B 0 -13,-0.3 -14,-2.6 -2,-0.3 2,-0.4 -0.806 15.3-154.7-115.9 158.5 38.7 55.8 15.5 71 393 A R E -EG 55 88B 60 17,-2.1 17,-3.2 -2,-0.3 2,-0.3 -0.996 13.0-168.9-134.7 129.5 42.2 54.4 15.0 72 394 A I E -EG 54 87B 0 -18,-2.6 -18,-2.3 -2,-0.4 2,-0.5 -0.895 17.7-159.5-121.8 149.2 45.2 56.6 14.4 73 395 A Y E > - G 0 86B 19 13,-2.6 3,-2.3 -2,-0.3 13,-2.1 -0.926 8.6-161.6-124.3 100.0 48.8 56.0 13.3 74 396 A L T 3 S+ 0 0 4 -2,-0.5 -21,-0.1 -22,-0.4 -1,-0.1 0.651 94.9 36.9 -59.6 -13.9 50.8 59.0 14.3 75 397 A N T 3 S- 0 0 27 -23,-0.5 7,-3.0 1,-0.2 -1,-0.3 -0.036 120.8-103.0-127.5 29.6 53.5 57.9 11.9 76 398 A G < - 0 0 6 -3,-2.3 2,-0.3 5,-0.3 -1,-0.2 0.294 25.5-123.5 72.7 162.5 51.3 56.6 9.1 77 399 A D > - 0 0 11 71,-0.4 3,-2.3 4,-0.1 4,-0.1 -0.988 64.1 -21.8-143.2 148.5 50.2 53.2 7.8 78 400 A G G > S+ 0 0 29 -2,-0.3 3,-2.5 1,-0.3 467,-0.1 -0.248 135.5 8.1 54.8-129.5 50.4 51.5 4.4 79 401 A T G 3 S+ 0 0 106 1,-0.3 -1,-0.3 3,-0.1 -3,-0.0 0.572 138.6 48.6 -59.6 -9.3 50.8 54.0 1.6 80 402 A G G X> S+ 0 0 0 -3,-2.3 4,-2.6 3,-0.1 3,-1.4 0.338 78.1 142.6-112.3 4.7 51.3 56.7 4.2 81 403 A R T <4 S- 0 0 176 -3,-2.5 -5,-0.3 1,-0.3 -4,-0.1 -0.217 80.6 -8.9 -50.5 122.6 53.8 54.8 6.3 82 404 A G T 34 S+ 0 0 35 -7,-3.0 -1,-0.3 2,-0.3 -6,-0.2 0.228 131.7 64.7 74.5 -15.1 56.4 57.2 7.7 83 405 A T T <4 S+ 0 0 73 -3,-1.4 70,-2.7 -8,-0.1 71,-0.3 0.698 101.5 30.4-109.9 -27.5 55.2 60.2 5.6 84 406 A H E < S- H 0 152B 42 -4,-2.6 2,-0.6 68,-0.3 -2,-0.3 -0.756 73.7-109.6-129.2 174.2 51.7 60.9 6.9 85 407 A L E - H 0 151B 0 66,-2.7 66,-1.6 -2,-0.2 65,-0.7 -0.914 41.2-151.6 -99.1 125.7 49.4 60.8 9.8 86 408 A S E -G 73 0B 0 -13,-2.1 -13,-2.6 -2,-0.6 2,-0.4 -0.909 13.2-171.8-106.3 133.3 47.0 58.1 9.0 87 409 A L E -GH 72 147B 0 60,-2.3 60,-3.0 -2,-0.5 2,-0.3 -0.987 4.9-175.6-127.5 128.7 43.4 58.2 10.4 88 410 A F E -GH 71 146B 0 -17,-3.2 -17,-2.1 -2,-0.4 2,-0.4 -0.848 21.3-132.4-124.9 159.8 40.8 55.4 10.2 89 411 A F E -GH 70 145B 2 56,-2.9 56,-2.5 -2,-0.3 2,-0.4 -0.851 23.2-156.9-106.3 141.9 37.2 54.8 11.1 90 412 A V E -G 69 0B 1 -21,-2.6 -21,-1.8 -2,-0.4 2,-0.7 -0.976 11.9-151.1-128.4 126.1 36.2 51.6 12.9 91 413 A V E -G 68 0B 1 -2,-0.4 51,-2.4 42,-0.4 -23,-0.2 -0.839 27.8-161.7 -91.6 120.2 32.9 49.8 13.1 92 414 A X E -GI 67 141B 17 -25,-2.4 2,-0.6 -2,-0.7 -25,-0.6 -0.612 29.6 -90.6-101.7 162.3 32.8 48.0 16.4 93 415 A K - 0 0 104 47,-3.0 -1,-0.1 -2,-0.2 -25,-0.1 -0.591 51.9-158.4 -70.6 114.3 30.6 45.1 17.6 94 416 A G > - 0 0 9 -2,-0.6 3,-0.9 -27,-0.1 4,-0.2 -0.571 26.0-122.7 -96.3 161.7 27.6 46.8 19.2 95 417 A P T 3 S+ 0 0 62 0, 0.0 3,-0.3 0, 0.0 -1,-0.1 0.830 114.3 38.8 -67.7 -32.1 25.1 45.5 21.8 96 418 A N T >> S+ 0 0 10 -31,-0.4 3,-2.3 1,-0.2 4,-0.6 0.099 74.3 122.9-106.4 19.7 22.2 46.2 19.5 97 419 A D G X4 S+ 0 0 2 -3,-0.9 3,-1.9 1,-0.3 -1,-0.2 0.870 70.1 62.8 -49.4 -41.5 23.8 45.1 16.2 98 420 A A G 34 S+ 0 0 21 1,-0.3 -1,-0.3 -3,-0.3 -2,-0.1 0.726 103.7 49.6 -57.7 -22.1 21.0 42.6 15.6 99 421 A L G <4 S+ 0 0 41 -3,-2.3 -1,-0.3 -35,-0.1 -2,-0.2 0.532 100.0 84.7 -94.7 -7.2 18.5 45.5 15.5 100 422 A L S << S- 0 0 39 -3,-1.9 2,-0.4 -4,-0.6 -35,-0.0 -0.538 82.0-107.6 -97.3 161.5 20.5 47.6 13.0 101 423 A R - 0 0 148 -2,-0.2 4,-0.2 2,-0.0 -2,-0.1 -0.697 46.8-114.5 -87.3 134.8 20.7 47.5 9.2 102 424 A W S S+ 0 0 57 -2,-0.4 2,-0.1 2,-0.1 33,-0.1 -0.931 82.1 42.4-125.4 151.0 23.8 46.1 7.6 103 425 A P S S- 0 0 37 0, 0.0 32,-0.2 0, 0.0 2,-0.2 0.545 90.9-111.1 -74.2 165.5 26.2 46.8 6.0 104 426 A F + 0 0 0 30,-3.0 -2,-0.1 -2,-0.1 -13,-0.0 -0.455 42.4 173.7 -61.4 127.7 27.1 50.1 7.7 105 427 A N + 0 0 86 -4,-0.2 2,-0.4 -2,-0.2 -1,-0.1 -0.148 24.9 125.4-135.3 43.8 26.3 52.8 5.1 106 428 A Q - 0 0 7 20,-0.0 2,-0.2 70,-0.0 70,-0.1 -0.821 61.3-112.4-106.5 143.6 26.8 56.2 6.7 107 429 A K - 0 0 58 -2,-0.4 68,-2.4 19,-0.1 2,-0.4 -0.474 34.1-156.1 -69.5 139.4 29.0 59.0 5.4 108 430 A V E -BC 125 174A 0 17,-2.4 17,-2.0 66,-0.2 2,-0.5 -0.969 10.1-166.5-124.3 135.4 31.9 59.7 7.7 109 431 A T E -BC 124 173A 29 64,-2.3 64,-2.4 -2,-0.4 2,-0.4 -0.978 6.8-165.1-122.6 128.2 33.9 62.9 8.0 110 432 A L E -BC 123 172A 0 13,-3.0 13,-1.9 -2,-0.5 2,-0.4 -0.885 8.2-175.4-114.0 144.8 37.3 63.0 9.8 111 433 A X E -BC 122 171A 19 60,-2.3 60,-2.6 -2,-0.4 2,-0.6 -0.995 27.2-153.6-144.6 145.1 39.1 66.1 10.9 112 434 A L E -BC 121 170A 1 9,-2.4 9,-2.2 -2,-0.4 2,-0.2 -0.979 40.1-132.5-111.1 112.9 42.3 67.2 12.5 113 435 A L - 0 0 13 56,-2.5 2,-0.6 -2,-0.6 56,-0.4 -0.493 1.8-135.0 -78.4 138.3 41.4 70.4 14.3 114 436 A D > - 0 0 5 -2,-0.2 3,-1.6 1,-0.1 48,-0.3 -0.779 12.0-148.0 -84.6 121.0 43.4 73.6 14.0 115 437 A Q T 3 S+ 0 0 16 46,-3.9 47,-0.1 -2,-0.6 -1,-0.1 0.294 99.1 58.7 -78.1 14.9 43.6 74.9 17.6 116 438 A N T 3 S- 0 0 93 45,-0.2 -1,-0.3 3,-0.1 46,-0.1 -0.046 112.0-121.4-124.3 21.7 43.7 78.4 16.0 117 439 A N S < S+ 0 0 128 -3,-1.6 3,-0.1 44,-0.2 -2,-0.1 0.698 80.4 115.4 41.0 27.1 40.3 77.8 14.4 118 440 A R S S- 0 0 66 1,-0.2 2,-0.7 43,-0.1 -4,-0.1 0.690 76.3 -6.4 -86.6-112.2 42.1 78.5 11.1 119 441 A E - 0 0 64 -6,-0.1 2,-0.3 -3,-0.0 -1,-0.2 -0.799 67.2-158.3 -94.7 115.7 42.4 75.7 8.5 120 442 A H - 0 0 57 -2,-0.7 2,-0.6 -3,-0.1 -7,-0.2 -0.718 22.3-119.4 -90.6 139.6 41.2 72.3 9.7 121 443 A V E +B 112 0A 29 -9,-2.2 -9,-2.4 -2,-0.3 2,-0.4 -0.704 46.3 177.7 -78.6 122.6 42.5 69.2 8.0 122 444 A I E +B 111 0A 97 -2,-0.6 2,-0.3 -11,-0.2 -11,-0.2 -0.970 19.0 159.2-133.9 146.0 39.4 67.5 6.6 123 445 A D E -B 110 0A 76 -13,-1.9 -13,-3.0 -2,-0.4 2,-0.3 -0.961 12.3-171.1-157.9 147.9 38.5 64.5 4.6 124 446 A A E -B 109 0A 35 -2,-0.3 2,-0.3 -15,-0.3 -15,-0.2 -0.873 2.7-176.4-137.2 169.2 35.3 62.5 4.2 125 447 A F E -B 108 0A 16 -17,-2.0 -17,-2.4 -2,-0.3 -2,-0.0 -0.986 24.2-127.2-165.0 156.9 34.2 59.3 2.6 126 448 A R - 0 0 157 -2,-0.3 -19,-0.1 -19,-0.2 -21,-0.0 -0.920 43.7-103.9-109.3 135.1 31.2 57.1 1.8 127 449 A P - 0 0 7 0, 0.0 2,-1.0 0, 0.0 -1,-0.0 -0.152 19.1-126.7 -56.3 150.5 31.5 53.4 2.9 128 450 A D > - 0 0 44 1,-0.1 3,-2.6 414,-0.0 6,-0.3 -0.880 23.7-153.7 -96.7 98.7 32.1 50.7 0.3 129 451 A V T 3 S+ 0 0 58 -2,-1.0 -1,-0.1 1,-0.3 -25,-0.0 0.596 90.7 53.6 -54.3 -12.5 29.1 48.6 1.3 130 452 A T T 3 S+ 0 0 115 -27,-0.1 -1,-0.3 5,-0.0 2,-0.1 0.548 85.6 106.4 -98.9 -9.1 30.9 45.5 0.1 131 453 A S S X S- 0 0 20 -3,-2.6 3,-1.6 1,-0.1 4,-0.2 -0.410 75.7-129.8 -70.1 144.8 34.0 46.1 2.2 132 454 A S G > S+ 0 0 62 1,-0.3 3,-0.8 2,-0.2 11,-0.2 0.712 104.1 73.9 -65.9 -20.2 34.5 43.8 5.2 133 455 A S G 3 S+ 0 0 1 1,-0.2 -42,-0.4 9,-0.1 -1,-0.3 0.682 104.1 37.6 -67.0 -17.9 35.1 47.0 7.2 134 456 A F G < S+ 0 0 2 -3,-1.6 -30,-3.0 -6,-0.3 -1,-0.2 0.300 90.4 101.1-120.0 8.7 31.4 47.7 7.0 135 457 A Q S < S- 0 0 71 -3,-0.8 3,-0.1 -32,-0.2 7,-0.1 -0.374 93.5 -66.2 -83.9 171.9 29.7 44.3 7.4 136 458 A R - 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