==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=5-JAN-2010 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER IMMUNE SYSTEM 22-MAR-07 2UWN . COMPND 2 MOLECULE: HUMAN COMPLEMENT FACTOR H; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR B.E.PROSSER,S.JOHNSON,P.ROVERSI,A.P.HERBERT,B.S.BLAUM, . 187 1 6 6 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 12247.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 99 52.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 53 28.3 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 3 1.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 3 1.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 19 10.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 18 9.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 3 1.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 1 5 6 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 6 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 320 A M 0 0 163 0, 0.0 2,-0.4 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 -95.5 -25.4 57.1 59.8 2 321 A G - 0 0 48 2,-0.1 2,-1.3 3,-0.0 27,-0.0 -0.958 360.0-166.7-136.5 120.8 -24.5 54.5 57.1 3 322 A L - 0 0 115 -2,-0.4 27,-0.2 27,-0.1 -1,-0.0 -0.481 64.1-138.5 -90.7 59.0 -21.2 53.4 55.6 4 323 A K - 0 0 118 -2,-1.3 25,-0.1 25,-0.1 -2,-0.1 -0.593 14.2 -57.2-114.1-178.0 -23.4 51.9 53.0 5 324 A P - 0 0 67 0, 0.0 2,-0.3 0, 0.0 24,-0.3 0.989 24.2-130.4-105.6-176.5 -24.2 49.7 51.0 6 325 A a B -A 28 0A 11 22,-3.8 22,-4.0 53,-0.1 2,-0.1 -0.775 26.3-134.0-102.4 146.7 -23.1 47.3 47.9 7 326 A D - 0 0 115 -2,-0.3 -1,-0.1 20,-0.2 3,-0.0 -0.279 48.1 -58.0 -89.4 178.0 -25.0 46.7 44.6 8 327 A Y - 0 0 59 1,-0.1 2,-0.8 -2,-0.1 -1,-0.2 -0.348 60.5-117.2 -58.9 126.7 -25.8 43.4 42.8 9 328 A P - 0 0 9 0, 0.0 2,-1.6 0, 0.0 7,-0.2 -0.580 17.2-150.8 -75.9 110.2 -22.5 41.7 42.0 10 329 A D - 0 0 125 -2,-0.8 2,-0.7 5,-0.1 5,-0.1 -0.661 21.5-159.5 -77.7 89.4 -22.2 41.4 38.3 11 330 A I > - 0 0 16 -2,-1.6 3,-1.2 3,-0.1 2,-0.3 -0.674 5.9-143.9 -81.2 112.4 -20.1 38.3 38.5 12 331 A K T 3 S+ 0 0 135 -2,-0.7 54,-0.3 1,-0.3 3,-0.1 -0.609 85.1 2.6 -75.5 129.2 -18.1 37.7 35.2 13 332 A H T 3 S+ 0 0 61 -2,-0.3 26,-3.0 1,-0.3 -1,-0.3 0.698 133.2 48.0 66.9 22.6 -17.8 34.0 34.4 14 333 A G E < -B 38 0B 16 -3,-1.2 2,-0.3 24,-0.3 -1,-0.3 -0.812 65.7-147.0-160.7-160.3 -20.0 33.1 37.4 15 334 A G E -B 37 0B 11 22,-2.0 22,-3.0 -2,-0.2 2,-0.3 -0.963 26.5 -89.8-178.2 162.8 -23.2 33.9 39.3 16 335 A L E > -B 36 0B 5 -2,-0.3 3,-0.5 20,-0.3 20,-0.3 -0.646 38.3-124.2 -86.5 141.4 -24.9 34.0 42.6 17 336 A Y T 3 S+ 0 0 82 18,-2.0 5,-0.2 -2,-0.3 18,-0.1 -0.455 96.1 24.9 -75.6 158.0 -26.8 31.0 44.0 18 337 A H T >> S+ 0 0 124 -2,-0.1 4,-2.0 1,-0.1 3,-0.6 0.905 76.5 170.5 51.2 46.3 -30.4 31.5 44.9 19 338 A E H <> S+ 0 0 82 -3,-0.5 4,-1.3 1,-0.2 -2,-0.1 0.863 70.4 52.6 -54.7 -42.8 -30.5 34.4 42.4 20 339 A N H 34 S+ 0 0 113 1,-0.2 -1,-0.2 2,-0.2 -2,-0.1 0.794 111.5 45.8 -65.8 -32.4 -34.3 34.7 42.6 21 340 A M H <4 S+ 0 0 110 -3,-0.6 -2,-0.2 1,-0.1 -1,-0.2 0.875 113.6 46.0 -78.8 -40.9 -34.4 35.0 46.5 22 341 A R H >X S+ 0 0 33 -4,-2.0 3,-2.0 -5,-0.2 4,-0.5 0.683 90.8 106.6 -79.3 -21.1 -31.5 37.5 46.9 23 342 A R T 3< S+ 0 0 128 -4,-1.3 -1,-0.0 1,-0.3 -5,-0.0 -0.888 82.1 20.5 -99.7 124.3 -32.7 39.8 44.2 24 343 A P T 34 S+ 0 0 109 0, 0.0 -1,-0.3 0, 0.0 -2,-0.1 -0.491 91.0 94.1 -97.9 42.0 -34.0 42.5 45.1 25 344 A Y T <4 S+ 0 0 138 -3,-2.0 -2,-0.2 -4,-0.1 -3,-0.1 0.747 75.1 145.2 -64.0 -13.2 -32.6 42.9 48.8 26 345 A F < + 0 0 31 -4,-0.5 2,-0.2 2,-0.1 -19,-0.1 -0.459 36.3 64.0 -75.3 145.8 -29.9 45.0 46.9 27 346 A P S S- 0 0 78 0, 0.0 2,-0.4 0, 0.0 -20,-0.2 0.418 90.0-154.3 -54.8 143.7 -28.4 47.5 47.6 28 347 A V B -A 6 0A 0 -22,-4.0 -22,-3.8 -2,-0.2 -2,-0.1 -0.819 10.7-114.2-106.0 138.3 -26.9 45.2 50.3 29 348 A A > - 0 0 40 -2,-0.4 3,-1.3 -24,-0.3 26,-0.2 -0.266 41.8 -88.7 -68.0 154.2 -25.5 46.4 53.6 30 349 A V T 3 S+ 0 0 59 1,-0.2 26,-0.2 -27,-0.2 -1,-0.1 -0.349 113.0 35.5 -63.9 141.7 -21.8 45.9 54.4 31 350 A G T 3 S+ 0 0 53 24,-2.0 -1,-0.2 1,-0.5 25,-0.1 -0.142 86.3 121.2 102.9 -34.8 -20.9 42.6 56.0 32 351 A K < - 0 0 97 -3,-1.3 23,-2.5 22,-0.1 -1,-0.5 -0.331 42.0-174.2 -58.6 140.9 -23.5 40.7 54.0 33 352 A Y E - C 0 54B 137 21,-0.2 2,-0.4 -3,-0.1 21,-0.2 -0.994 8.5-155.9-141.0 145.9 -21.9 37.9 51.9 34 353 A Y E - C 0 53B 23 19,-2.3 19,-2.9 -2,-0.3 2,-0.2 -0.962 20.6-117.3-128.2 144.1 -23.4 35.6 49.4 35 354 A S E + C 0 52B 17 -2,-0.4 -18,-2.0 17,-0.2 2,-0.3 -0.521 40.4 176.8 -72.7 137.2 -22.5 32.2 48.0 36 355 A Y E -BC 16 51B 0 15,-3.0 15,-2.2 -20,-0.3 2,-0.3 -0.934 18.1-142.0-140.0 161.4 -21.6 32.2 44.3 37 356 A Y E -BC 15 50B 82 -22,-3.0 -22,-2.0 -2,-0.3 2,-0.4 -0.755 11.5-131.9-118.9 168.7 -20.5 29.7 41.7 38 357 A b E -B 14 0B 11 11,-2.2 -24,-0.3 -2,-0.3 4,-0.1 -0.958 27.5-113.3-121.6 141.6 -18.1 29.9 38.7 39 358 A D > - 0 0 71 -26,-3.0 3,-1.7 -2,-0.4 -1,-0.1 -0.066 51.2 -66.4 -65.0 170.3 -18.9 28.7 35.2 40 359 A E T 3 S+ 0 0 154 1,-0.3 -1,-0.2 -26,-0.0 3,-0.1 -0.254 125.8 26.7 -55.0 144.5 -17.1 25.7 33.5 41 360 A H T 3 S+ 0 0 78 1,-0.2 28,-2.4 -3,-0.1 2,-0.3 0.529 111.4 90.9 75.2 6.3 -13.4 26.5 32.8 42 361 A F E < -E 68 0C 18 -3,-1.7 2,-0.3 26,-0.3 26,-0.2 -0.927 53.7-168.4-133.1 157.0 -13.4 28.9 35.7 43 362 A E E -E 67 0C 46 24,-3.3 24,-3.5 -2,-0.3 6,-0.2 -0.952 23.9-109.4-142.4 159.4 -12.6 28.7 39.4 44 363 A T > - 0 0 1 4,-3.2 3,-2.3 -2,-0.3 22,-0.2 -0.478 42.8-101.6 -83.1 159.9 -12.8 30.7 42.7 45 364 A P T 3 S+ 0 0 69 0, 0.0 -1,-0.1 0, 0.0 21,-0.1 0.831 125.3 58.6 -48.2 -35.8 -9.7 32.1 44.4 46 365 A S T 3 S- 0 0 77 2,-0.1 3,-0.1 1,-0.1 5,-0.0 0.705 121.5-110.0 -68.0 -21.6 -9.9 29.2 46.8 47 366 A G S < S+ 0 0 37 -3,-2.3 2,-0.2 1,-0.4 -1,-0.1 0.499 82.4 107.6 102.9 7.9 -9.6 26.8 43.9 48 367 A S S S- 0 0 39 2,-0.1 -4,-3.2 1,-0.0 -1,-0.4 -0.494 80.7-110.8-107.5 179.6 -13.2 25.4 44.0 49 368 A Y S S+ 0 0 149 -6,-0.2 -11,-2.2 -2,-0.2 2,-0.3 0.455 100.2 35.7 -87.6 -4.7 -16.3 25.9 41.8 50 369 A W E +C 37 0B 104 -13,-0.2 2,-0.2 -6,-0.1 -13,-0.2 -0.998 61.9 142.1-150.1 148.3 -18.0 27.9 44.5 51 370 A D E -C 36 0B 44 -15,-2.2 -15,-3.0 -2,-0.3 2,-0.4 -0.841 45.5 -78.1-159.7-163.3 -17.2 30.4 47.3 52 371 A H E -C 35 0B 60 -17,-0.3 2,-0.4 -2,-0.2 -17,-0.2 -0.961 26.8-153.8-119.6 132.1 -18.5 33.5 49.1 53 372 A I E -C 34 0B 1 -19,-2.9 -19,-2.3 -2,-0.4 2,-0.4 -0.866 17.5-150.8-101.2 137.5 -18.4 37.1 47.9 54 373 A H E -CD 33 61B 74 7,-4.1 7,-2.7 -2,-0.4 2,-1.0 -0.914 15.1-128.6-117.2 135.9 -18.4 39.8 50.6 55 374 A a E - D 0 60B 3 -23,-2.5 -24,-2.0 -2,-0.4 5,-0.2 -0.691 38.3-176.2 -80.0 102.6 -19.7 43.3 50.5 56 375 A T E > - D 0 59B 54 3,-3.4 3,-2.0 -2,-1.0 -24,-0.0 -0.529 42.8-106.5 -96.0 165.9 -16.7 45.4 51.7 57 376 A Q T 3 S+ 0 0 133 1,-0.3 3,-0.1 -2,-0.2 -1,-0.1 0.723 126.3 47.4 -62.5 -21.2 -16.5 49.1 52.4 58 377 A D T 3 S- 0 0 143 1,-0.4 -1,-0.3 -52,-0.0 2,-0.2 0.110 128.2 -89.3-106.0 18.7 -14.5 49.3 49.2 59 378 A G E < S-D 56 0B 29 -3,-2.0 -3,-3.4 2,-0.0 -1,-0.4 -0.712 77.2 -7.8 111.0-161.2 -16.9 47.1 47.2 60 379 A W E S-D 55 0B 51 -2,-0.2 -5,-0.2 -5,-0.2 -27,-0.0 -0.498 70.4-121.7 -76.5 140.8 -17.2 43.3 46.6 61 380 A S E S+D 54 0B 53 -7,-2.7 -7,-4.1 -2,-0.2 2,-0.1 -0.996 94.8 39.5-134.4 128.0 -14.5 41.0 47.8 62 381 A P S S- 0 0 34 0, 0.0 -1,-0.1 0, 0.0 4,-0.1 0.458 78.4-155.0 -66.8 151.6 -12.9 39.1 46.1 63 382 A A S S+ 0 0 93 1,-0.3 -2,-0.1 -2,-0.1 -3,-0.1 0.800 93.1 36.3 -68.2 -31.9 -12.7 41.7 43.3 64 383 A V S S+ 0 0 76 1,-0.1 -1,-0.3 -53,-0.1 3,-0.1 -0.807 73.1 173.6-123.0 85.3 -12.2 38.8 40.7 65 384 A P + 0 0 20 0, 0.0 2,-0.5 0, 0.0 -1,-0.1 0.770 68.5 44.9 -66.7 -29.9 -14.5 36.0 42.0 66 385 A b - 0 0 6 -54,-0.3 2,-0.3 -22,-0.2 -22,-0.2 -0.947 68.8-175.7-124.5 111.4 -14.0 33.8 39.1 67 386 A L E -E 43 0C 36 -24,-3.5 -24,-3.3 -2,-0.5 2,-0.1 -0.761 31.8-102.5-102.1 149.2 -10.5 33.2 37.6 68 387 A R E -E 42 0C 48 -2,-0.3 21,-1.9 -26,-0.2 2,-0.5 -0.367 23.0-145.0 -72.2 150.8 -9.8 31.1 34.5 69 388 A K E -F 88 0D 52 -28,-2.4 2,-0.4 19,-0.2 19,-0.2 -0.976 16.2-155.6-116.4 121.1 -8.5 27.6 34.6 70 389 A c E -F 87 0D 2 17,-3.4 17,-2.4 -2,-0.5 2,-0.5 -0.859 4.1-151.7-106.5 139.1 -6.1 26.6 31.8 71 390 A Y E -F 86 0D 65 -2,-0.4 15,-0.2 15,-0.2 46,-0.1 -0.922 19.2-130.5-111.5 116.4 -5.4 23.1 30.6 72 391 A F - 0 0 7 13,-2.3 12,-2.0 -2,-0.5 13,-0.2 -0.586 28.0-147.0 -73.5 123.1 -2.0 22.5 29.1 73 392 A P - 0 0 47 0, 0.0 2,-0.2 0, 0.0 9,-0.2 -0.231 24.9 -82.7 -84.6 173.9 -2.4 20.7 25.7 74 393 A Y - 0 0 142 9,-0.1 2,-0.7 6,-0.1 6,-0.0 -0.546 35.4-144.5 -75.3 141.5 -0.2 18.2 23.9 75 394 A L > - 0 0 9 -2,-0.2 3,-1.3 1,-0.2 47,-0.1 -0.893 14.8-175.6-110.8 100.9 2.8 19.6 22.0 76 395 A E T 3 S+ 0 0 146 -2,-0.7 -1,-0.2 1,-0.3 4,-0.1 0.828 89.5 35.6 -64.2 -32.9 3.4 17.6 18.9 77 396 A N T 3 S+ 0 0 41 46,-0.1 21,-2.4 2,-0.1 2,-0.3 -0.088 117.3 58.8-111.9 33.5 6.5 19.6 18.0 78 397 A G E < S-G 97 0E 3 -3,-1.3 2,-0.5 19,-0.3 19,-0.3 -0.915 91.1 -82.4-148.8 174.5 7.8 20.1 21.6 79 398 A Y E -G 96 0E 113 17,-3.4 2,-0.6 -2,-0.3 17,-0.5 -0.737 45.5-142.4 -86.2 127.2 8.9 18.5 24.8 80 399 A N + 0 0 55 -2,-0.5 -6,-0.1 1,-0.1 15,-0.0 -0.823 47.8 131.3-101.2 120.4 5.9 17.4 26.9 81 400 A Q S S+ 0 0 127 -2,-0.6 -1,-0.1 4,-0.0 -2,-0.0 0.472 78.6 42.0-133.9 -13.6 5.9 17.6 30.7 82 401 A N > + 0 0 31 -9,-0.2 3,-3.0 3,-0.1 2,-0.5 0.299 66.6 141.9-121.2 6.9 2.6 19.4 31.5 83 402 A H T 3 S+ 0 0 120 1,-0.3 -9,-0.1 -12,-0.1 3,-0.1 -0.365 82.4 15.3 -57.0 106.3 0.1 17.8 29.2 84 403 A G T 3 S+ 0 0 49 -12,-2.0 -1,-0.3 -2,-0.5 2,-0.1 0.235 94.7 130.0 111.7 -9.9 -3.1 17.6 31.3 85 404 A R < - 0 0 139 -3,-3.0 -13,-2.3 -13,-0.2 -1,-0.4 -0.467 49.5-137.7 -76.6 148.5 -2.0 19.9 34.1 86 405 A K E -F 71 0D 115 -15,-0.2 2,-0.4 -2,-0.1 -15,-0.2 -0.865 18.7-171.7-108.4 140.8 -4.3 22.7 35.2 87 406 A F E -F 70 0D 23 -17,-2.4 -17,-3.4 -2,-0.4 2,-0.2 -0.993 19.2-125.9-135.6 140.0 -3.2 26.3 35.9 88 407 A V E > -F 69 0D 46 -2,-0.4 3,-1.5 -19,-0.2 24,-0.3 -0.512 46.4 -78.4 -82.5 152.0 -5.0 29.2 37.4 89 408 A Q T 3 S+ 0 0 58 -21,-1.9 24,-0.2 1,-0.2 -1,-0.2 -0.097 117.7 34.6 -47.8 140.4 -5.1 32.6 35.7 90 409 A G T 3 S+ 0 0 62 22,-3.6 2,-0.3 1,-0.3 -1,-0.2 0.330 88.4 128.4 92.8 -6.1 -2.0 34.7 36.0 91 410 A K < - 0 0 115 -3,-1.5 21,-2.5 21,-0.3 2,-0.4 -0.671 44.8-154.1 -88.8 137.7 0.3 31.6 35.9 92 411 A S E -H 111 0F 67 -2,-0.3 2,-0.4 19,-0.2 19,-0.2 -0.906 9.0-166.3-111.6 136.1 3.2 31.4 33.5 93 412 A I E -H 110 0F 22 17,-2.3 17,-2.0 -2,-0.4 2,-0.2 -0.974 22.0-118.7-125.9 137.3 4.6 28.1 32.3 94 413 A D E -H 109 0F 120 -2,-0.4 2,-0.5 15,-0.2 15,-0.2 -0.474 25.7-155.9 -71.9 141.4 7.9 27.3 30.5 95 414 A V - 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