==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER GLUTATHIONE REDUCTASE 26-JAN-96 1XAN . COMPND 2 MOLECULE: GLUTATHIONE REDUCTASE; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR S.N.SAVVIDES,P.A.KARPLUS . 461 1 1 1 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 22693.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 324 70.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 38 8.2 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 65 14.1 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 2 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 1 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 36 7.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 52 11.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 110 23.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 11 2.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 1 1 0 1 0 0 0 2 1 1 0 2 0 0 0 0 0 0 0 0 0 1 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 1 3 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 3 1 1 2 1 1 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 1 1 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 18 A V 0 0 106 0, 0.0 2,-0.3 0, 0.0 129,-0.2 0.000 360.0 360.0 360.0 107.2 34.9 -30.8 51.3 2 19 A A E -a 130 0A 46 127,-1.7 129,-2.4 130,-0.0 2,-0.3 -0.628 360.0-148.0 -75.6 132.8 36.4 -30.3 47.8 3 20 A S E +a 131 0A 84 -2,-0.3 2,-0.3 127,-0.2 129,-0.2 -0.779 20.2 173.8-107.8 146.8 38.8 -33.1 47.0 4 21 A Y - 0 0 23 127,-1.4 130,-0.2 -2,-0.3 25,-0.2 -0.834 40.1-120.4-136.4 174.7 42.0 -33.0 44.9 5 22 A D S S+ 0 0 70 23,-2.6 129,-0.5 1,-0.3 2,-0.4 0.799 102.3 18.4 -87.1 -31.2 44.8 -35.4 44.1 6 23 A Y E -d 29 0B 0 22,-1.5 24,-1.8 127,-0.1 2,-0.5 -0.985 63.5-168.8-147.4 125.5 47.4 -33.1 45.6 7 24 A L E -de 30 135B 0 127,-2.1 129,-2.9 -2,-0.4 2,-0.5 -0.976 10.4-164.8-116.6 120.5 47.0 -30.2 47.9 8 25 A V E -de 31 136B 0 22,-2.4 24,-3.0 -2,-0.5 2,-0.8 -0.919 7.5-154.2-109.9 125.2 50.1 -28.0 48.4 9 26 A I E S+de 32 137B 6 127,-3.2 129,-3.1 -2,-0.5 24,-0.1 -0.877 70.6 33.2-102.1 108.2 50.2 -25.6 51.4 10 27 A G - 0 0 9 22,-2.7 2,-0.2 -2,-0.8 23,-0.2 0.296 64.5-140.5 116.2 117.9 52.5 -22.8 50.5 11 28 A G + 0 0 0 4,-0.1 27,-2.5 20,-0.1 28,-0.5 -0.294 66.2 106.4 -99.9 47.9 53.1 -21.2 47.1 12 29 A G S > S- 0 0 12 126,-0.4 4,-2.6 -2,-0.2 5,-0.4 -0.210 89.3 -55.1-105.4-156.8 56.9 -20.8 47.4 13 30 A S H > S+ 0 0 29 25,-0.3 4,-1.6 1,-0.2 5,-0.2 0.902 133.7 32.9 -49.5 -59.0 59.9 -22.5 45.9 14 31 A G H > S+ 0 0 5 2,-0.2 4,-1.8 1,-0.2 -1,-0.2 0.864 119.1 51.7 -71.2 -37.0 59.1 -26.1 46.9 15 32 A G H > S+ 0 0 0 123,-0.3 4,-2.4 2,-0.2 5,-0.2 0.938 112.1 43.4 -66.0 -48.9 55.3 -25.8 46.7 16 33 A L H X S+ 0 0 10 -4,-2.6 4,-2.7 1,-0.2 5,-0.3 0.940 114.6 50.6 -61.8 -47.0 55.1 -24.4 43.2 17 34 A A H X S+ 0 0 6 -4,-1.6 4,-1.7 -5,-0.4 -1,-0.2 0.864 114.0 44.3 -58.5 -42.5 57.7 -26.8 41.9 18 35 A S H X S+ 0 0 0 -4,-1.8 4,-2.2 2,-0.2 -1,-0.2 0.907 113.9 49.2 -70.3 -43.1 56.0 -29.9 43.4 19 36 A A H X S+ 0 0 0 -4,-2.4 4,-2.4 2,-0.2 -2,-0.2 0.919 112.6 48.5 -63.4 -44.7 52.5 -28.8 42.3 20 37 A R H X S+ 0 0 69 -4,-2.7 4,-1.9 2,-0.2 -1,-0.2 0.918 112.9 45.4 -64.3 -43.1 53.6 -28.1 38.7 21 38 A R H X S+ 0 0 55 -4,-1.7 4,-0.9 -5,-0.3 -1,-0.2 0.883 112.5 52.5 -69.5 -37.0 55.4 -31.4 38.3 22 39 A A H ><>S+ 0 0 0 -4,-2.2 5,-2.0 1,-0.2 3,-0.8 0.921 108.0 51.3 -61.3 -45.0 52.5 -33.3 39.8 23 40 A A H ><5S+ 0 0 20 -4,-2.4 3,-2.1 1,-0.3 -2,-0.2 0.893 104.6 56.8 -59.7 -41.3 50.1 -31.6 37.3 24 41 A E H 3<5S+ 0 0 128 -4,-1.9 -1,-0.3 1,-0.3 -2,-0.2 0.766 104.5 54.1 -59.2 -30.7 52.3 -32.6 34.4 25 42 A L T <<5S- 0 0 54 -4,-0.9 -1,-0.3 -3,-0.8 -2,-0.2 0.386 130.8 -93.6 -84.8 0.8 51.9 -36.2 35.6 26 43 A G T < 5S+ 0 0 64 -3,-2.1 -3,-0.2 1,-0.3 2,-0.2 0.374 76.1 142.6 106.2 -6.4 48.1 -35.9 35.6 27 44 A A < - 0 0 10 -5,-2.0 2,-0.9 -6,-0.1 -1,-0.3 -0.478 52.1-132.0 -73.6 139.1 47.3 -34.9 39.1 28 45 A R - 0 0 100 -2,-0.2 -23,-2.6 78,-0.1 -22,-1.5 -0.813 44.1-179.2 -86.8 108.7 44.5 -32.4 39.7 29 46 A A E -d 6 0B 1 -2,-0.9 78,-2.1 76,-0.2 2,-0.3 -0.828 23.6-166.6-117.4 153.5 46.4 -30.1 42.1 30 47 A A E -df 7 107B 0 -24,-1.8 -22,-2.4 -2,-0.3 2,-0.4 -0.974 10.9-149.4-135.9 145.3 45.6 -26.9 44.1 31 48 A V E -df 8 108B 0 76,-3.0 78,-3.2 -2,-0.3 2,-0.5 -0.975 6.6-150.5-118.2 131.1 48.1 -24.6 45.8 32 49 A V E +df 9 109B 3 -24,-3.0 -22,-2.7 -2,-0.4 2,-0.4 -0.895 23.1 167.7-100.7 129.2 47.2 -22.6 49.0 33 50 A E E - f 0 110B 23 76,-2.1 78,-2.1 -2,-0.5 4,-0.1 -0.982 23.3-172.6-145.1 128.0 49.0 -19.3 49.4 34 51 A S S S+ 0 0 53 -2,-0.4 78,-0.2 76,-0.3 -1,-0.1 0.535 79.8 17.1 -93.2 -14.3 48.2 -16.6 51.9 35 52 A H S S- 0 0 152 76,-0.2 2,-0.4 1,-0.1 -2,-0.1 0.069 113.2 -23.3-124.2-118.9 50.6 -14.0 50.5 36 53 A K > - 0 0 134 -2,-0.1 3,-1.5 1,-0.0 7,-0.1 -0.862 59.4-115.9-110.8 136.2 52.5 -13.7 47.3 37 54 A L T 3 S+ 0 0 18 -2,-0.4 -25,-0.2 1,-0.2 60,-0.1 -0.293 100.5 49.3 -62.4 148.5 53.4 -16.5 44.9 38 55 A G T 3> S- 0 0 2 -27,-2.5 4,-1.5 59,-0.1 -25,-0.3 0.172 94.4-150.2 105.6 -22.6 57.1 -17.1 44.6 39 56 A G H <> - 0 0 15 -3,-1.5 4,-1.9 -28,-0.5 5,-0.4 -0.011 52.9 -19.4 60.1-149.6 57.4 -17.1 48.4 40 57 A T H > S+ 0 0 56 1,-0.2 4,-2.4 3,-0.2 -1,-0.2 0.927 133.1 54.4 -59.9 -46.7 60.5 -16.0 50.2 41 58 A a H > S+ 0 0 16 -3,-0.2 6,-2.0 4,-0.2 4,-0.9 0.914 115.9 34.6 -55.8 -52.8 63.0 -16.3 47.3 42 59 A V H < S+ 0 0 5 -4,-1.5 -1,-0.2 4,-0.2 -2,-0.2 0.918 128.0 35.5 -70.3 -43.9 61.2 -14.2 44.8 43 60 A N H < S- 0 0 30 -4,-1.9 -3,-0.2 -7,-0.1 -2,-0.2 0.880 140.3 -3.3 -83.1 -43.3 59.8 -11.6 47.2 44 61 A V H < S+ 0 0 41 -4,-2.4 -3,-0.2 -5,-0.4 -2,-0.1 -0.102 124.1 46.3-144.4 39.1 62.3 -11.1 50.0 45 62 A G S X S+ 0 0 17 -4,-0.9 4,-2.3 -6,-0.1 5,-0.3 -0.254 105.2 3.2-144.6-127.3 65.1 -13.5 49.2 46 63 A a H > S+ 0 0 49 1,-0.2 4,-2.3 2,-0.2 -4,-0.2 0.794 123.8 45.7 -40.9 -56.6 67.2 -14.7 46.3 47 64 A V H > S+ 0 0 30 -6,-2.0 4,-2.1 2,-0.2 5,-0.2 0.984 116.5 38.3 -62.2 -62.7 65.9 -12.4 43.6 48 65 A P H > S+ 0 0 2 0, 0.0 4,-1.8 0, 0.0 -1,-0.2 0.891 117.7 54.7 -57.7 -32.1 65.8 -8.9 45.2 49 66 A K H X S+ 0 0 20 -4,-2.3 4,-2.3 -8,-0.3 -2,-0.2 0.932 107.1 49.0 -63.1 -46.7 69.1 -9.9 47.0 50 67 A K H X S+ 0 0 63 -4,-2.3 4,-2.8 -5,-0.3 -1,-0.2 0.877 109.1 51.8 -63.2 -40.6 70.9 -10.7 43.6 51 68 A V H X S+ 0 0 29 -4,-2.1 4,-1.4 1,-0.2 -1,-0.2 0.910 112.4 46.7 -61.0 -44.6 69.7 -7.4 42.0 52 69 A M H X S+ 0 0 0 -4,-1.8 4,-2.1 -5,-0.2 -2,-0.2 0.847 111.1 52.0 -66.0 -34.3 71.2 -5.6 45.1 53 70 A W H X S+ 0 0 18 -4,-2.3 4,-2.5 2,-0.2 -2,-0.2 0.924 107.1 52.4 -67.6 -42.2 74.4 -7.6 44.9 54 71 A N H X S+ 0 0 78 -4,-2.8 4,-1.2 1,-0.2 -1,-0.2 0.839 109.9 50.6 -60.5 -34.1 74.7 -6.7 41.1 55 72 A T H X S+ 0 0 20 -4,-1.4 4,-1.5 -5,-0.2 -1,-0.2 0.908 109.3 48.6 -68.8 -44.4 74.4 -3.1 42.3 56 73 A A H X S+ 0 0 0 -4,-2.1 4,-1.8 1,-0.2 -2,-0.2 0.868 106.5 58.5 -63.5 -37.9 77.1 -3.4 44.9 57 74 A V H X S+ 0 0 29 -4,-2.5 4,-2.0 1,-0.2 -1,-0.2 0.871 103.1 51.6 -59.8 -39.8 79.4 -5.1 42.4 58 75 A H H X S+ 0 0 130 -4,-1.2 4,-1.5 1,-0.2 -1,-0.2 0.912 107.7 54.5 -61.6 -44.4 79.2 -2.0 40.1 59 76 A S H < S+ 0 0 31 -4,-1.5 4,-0.4 1,-0.2 -2,-0.2 0.878 110.3 45.4 -57.0 -41.0 80.1 0.1 43.2 60 77 A E H >< S+ 0 0 27 -4,-1.8 3,-0.8 1,-0.2 4,-0.2 0.848 111.3 49.6 -71.3 -43.9 83.3 -2.0 43.8 61 78 A F H >< S+ 0 0 62 -4,-2.0 3,-1.8 1,-0.2 4,-0.3 0.757 97.2 71.4 -68.2 -24.3 84.6 -2.1 40.3 62 79 A M G >< S+ 0 0 84 -4,-1.5 3,-1.1 1,-0.3 4,-0.4 0.778 86.1 66.4 -62.0 -25.4 84.1 1.6 40.0 63 80 A H G < S+ 0 0 128 -3,-0.8 -1,-0.3 -4,-0.4 4,-0.2 0.720 101.2 51.6 -64.3 -22.8 87.1 1.9 42.4 64 81 A D G <> S+ 0 0 1 -3,-1.8 4,-1.4 -4,-0.2 -1,-0.2 0.434 78.6 96.8 -95.9 -0.7 89.2 0.4 39.5 65 82 A H T X4>S+ 0 0 58 -3,-1.1 5,-2.7 -4,-0.3 3,-0.6 0.925 84.3 48.3 -54.9 -50.5 88.2 2.7 36.7 66 83 A A G >45S+ 0 0 59 -4,-0.4 3,-1.4 1,-0.3 -1,-0.2 0.847 107.4 56.3 -61.8 -35.1 91.1 5.1 36.9 67 84 A D G 345S+ 0 0 49 1,-0.3 -1,-0.3 -4,-0.2 -2,-0.2 0.849 108.3 49.5 -64.8 -30.1 93.6 2.2 37.0 68 85 A Y G <<5S- 0 0 98 -4,-1.4 -1,-0.3 -3,-0.6 -2,-0.2 0.315 128.6 -96.3 -91.4 6.3 92.1 0.9 33.8 69 86 A G T < 5S+ 0 0 69 -3,-1.4 -3,-0.2 1,-0.3 -2,-0.1 0.553 82.8 127.6 93.9 8.8 92.4 4.3 32.1 70 87 A F < - 0 0 123 -5,-2.7 -1,-0.3 -6,-0.2 -2,-0.1 -0.682 62.3-104.6 -98.5 154.2 88.9 5.6 32.6 71 88 A P - 0 0 108 0, 0.0 2,-0.2 0, 0.0 -1,-0.1 -0.389 42.0-100.9 -70.6 151.2 87.8 8.9 34.2 72 89 A S - 0 0 100 -7,-0.1 2,-0.5 -2,-0.1 -9,-0.1 -0.516 27.5-129.1 -75.6 137.7 86.5 8.9 37.7 73 90 A C - 0 0 81 -2,-0.2 -1,-0.0 -11,-0.2 -8,-0.0 -0.810 25.6-126.8 -87.2 124.9 82.8 9.1 38.2 74 91 A E - 0 0 190 -2,-0.5 -1,-0.1 2,-0.0 -2,-0.0 0.870 45.3 -90.6 -39.7 -73.1 82.0 11.9 40.6 75 92 A G + 0 0 60 1,-0.2 -2,-0.1 -3,-0.1 -1,-0.0 -0.097 69.7 94.2-160.9-104.7 79.8 10.6 43.5 76 93 A K - 0 0 191 1,-0.1 2,-0.3 -2,-0.0 -1,-0.2 -0.011 41.0-150.9 -40.8 116.6 76.3 10.0 44.9 77 94 A F - 0 0 78 115,-0.2 2,-0.8 1,-0.0 -1,-0.1 -0.584 13.8-139.9 -83.1 139.5 74.5 6.6 44.4 78 95 A N >> - 0 0 89 -2,-0.3 4,-1.0 1,-0.2 3,-0.7 -0.841 14.7-171.4-110.3 104.3 70.8 6.8 44.3 79 96 A W H 3> S+ 0 0 8 -2,-0.8 4,-2.6 1,-0.2 3,-0.2 0.867 80.2 57.4 -58.8 -41.8 69.1 4.0 46.2 80 97 A R H 3> S+ 0 0 94 1,-0.2 4,-1.9 2,-0.2 -1,-0.2 0.772 96.5 61.8 -69.9 -20.8 65.6 4.6 45.1 81 98 A V H <> S+ 0 0 66 -3,-0.7 4,-1.5 2,-0.2 -1,-0.2 0.960 114.7 33.9 -65.5 -48.2 66.2 4.4 41.4 82 99 A I H X S+ 0 0 36 -4,-1.0 4,-2.2 2,-0.2 -2,-0.2 0.852 112.8 60.9 -78.2 -31.1 67.3 0.8 41.8 83 100 A K H X S+ 0 0 23 -4,-2.6 4,-2.3 1,-0.2 -1,-0.2 0.931 107.9 45.3 -61.5 -40.4 64.9 0.0 44.6 84 101 A E H X S+ 0 0 87 -4,-1.9 4,-2.0 2,-0.2 -1,-0.2 0.879 112.3 48.0 -71.3 -36.9 62.0 0.8 42.3 85 102 A K H X S+ 0 0 137 -4,-1.5 4,-1.8 2,-0.2 -1,-0.2 0.831 111.8 53.2 -71.4 -30.3 63.3 -1.1 39.3 86 103 A R H X S+ 0 0 4 -4,-2.2 4,-1.9 2,-0.2 -2,-0.2 0.943 108.7 47.7 -67.8 -48.0 63.9 -4.0 41.7 87 104 A D H X S+ 0 0 61 -4,-2.3 4,-2.1 1,-0.2 -2,-0.2 0.889 110.3 53.4 -59.4 -43.2 60.3 -3.9 43.0 88 105 A A H X S+ 0 0 41 -4,-2.0 4,-2.1 1,-0.2 -1,-0.2 0.908 107.2 51.6 -59.4 -41.0 59.0 -3.8 39.4 89 106 A Y H X S+ 0 0 92 -4,-1.8 4,-2.0 1,-0.2 -1,-0.2 0.867 108.2 50.5 -65.5 -38.1 61.0 -6.9 38.5 90 107 A V H X S+ 0 0 15 -4,-1.9 4,-2.6 2,-0.2 -1,-0.2 0.894 108.6 52.9 -66.7 -38.7 59.6 -8.8 41.5 91 108 A S H X S+ 0 0 74 -4,-2.1 4,-1.8 2,-0.2 -2,-0.2 0.896 107.7 52.0 -61.7 -40.8 56.1 -7.7 40.3 92 109 A R H X S+ 0 0 144 -4,-2.1 4,-1.7 1,-0.2 -2,-0.2 0.911 110.0 48.6 -62.5 -41.9 56.9 -9.1 36.9 93 110 A L H X S+ 0 0 20 -4,-2.0 4,-2.5 1,-0.2 5,-0.2 0.924 106.6 55.0 -66.7 -42.3 58.0 -12.4 38.4 94 111 A N H X S+ 0 0 27 -4,-2.6 4,-1.8 1,-0.2 -1,-0.2 0.921 109.7 48.3 -57.0 -40.0 54.8 -12.7 40.5 95 112 A A H X S+ 0 0 60 -4,-1.8 4,-2.1 1,-0.2 -1,-0.2 0.850 110.4 51.7 -68.2 -34.4 52.7 -12.3 37.4 96 113 A I H X S+ 0 0 85 -4,-1.7 4,-2.1 2,-0.2 -1,-0.2 0.915 109.6 48.6 -67.2 -44.4 54.8 -15.0 35.6 97 114 A Y H X S+ 0 0 79 -4,-2.5 4,-1.6 2,-0.2 -2,-0.2 0.838 110.3 51.1 -65.6 -37.2 54.4 -17.5 38.4 98 115 A Q H X S+ 0 0 89 -4,-1.8 4,-2.4 -5,-0.2 3,-0.4 0.956 110.5 49.5 -64.2 -47.0 50.6 -17.0 38.5 99 116 A N H X S+ 0 0 79 -4,-2.1 4,-2.7 1,-0.2 -2,-0.2 0.874 107.0 56.1 -59.8 -37.2 50.5 -17.5 34.8 100 117 A N H X S+ 0 0 35 -4,-2.1 4,-0.6 2,-0.2 -1,-0.2 0.872 108.6 46.4 -64.2 -37.7 52.5 -20.7 35.1 101 118 A L H >X>S+ 0 0 1 -4,-1.6 5,-2.2 -3,-0.4 3,-1.3 0.965 112.6 49.3 -70.1 -47.6 50.1 -22.2 37.6 102 119 A T H ><5S+ 0 0 70 -4,-2.4 3,-1.8 1,-0.3 -2,-0.2 0.922 108.1 53.5 -58.7 -44.8 47.0 -21.2 35.5 103 120 A K H 3<5S+ 0 0 131 -4,-2.7 -1,-0.3 1,-0.3 -2,-0.2 0.685 109.9 48.8 -63.5 -19.7 48.5 -22.7 32.3 104 121 A S H <<5S- 0 0 37 -3,-1.3 -1,-0.3 -4,-0.6 -2,-0.2 0.432 115.3-117.8 -98.6 0.1 49.1 -26.0 34.1 105 122 A H T <<5 + 0 0 153 -3,-1.8 2,-0.5 -4,-0.5 -76,-0.2 0.757 60.4 153.4 68.8 28.8 45.5 -26.0 35.4 106 123 A I < - 0 0 7 -5,-2.2 2,-0.3 -6,-0.1 -1,-0.3 -0.756 42.5-130.1 -89.7 130.7 46.6 -25.8 39.0 107 124 A E E -f 30 0B 78 -78,-2.1 -76,-3.0 -2,-0.5 2,-0.6 -0.649 13.5-147.3 -81.5 136.2 44.0 -24.1 41.2 108 125 A I E -f 31 0B 26 -2,-0.3 2,-0.6 -78,-0.2 -76,-0.2 -0.946 9.4-166.1-106.9 115.8 45.2 -21.3 43.5 109 126 A I E -f 32 0B 15 -78,-3.2 -76,-2.1 -2,-0.6 2,-0.4 -0.930 15.4-146.2-102.7 115.0 43.3 -21.1 46.8 110 127 A R E +f 33 0B 160 -2,-0.6 -76,-0.3 -78,-0.2 2,-0.2 -0.706 52.3 51.5 -86.5 133.6 44.2 -17.8 48.4 111 128 A G S S- 0 0 17 -78,-2.1 2,-0.6 -2,-0.4 -76,-0.2 -0.744 88.8 -50.3 136.2 178.2 44.3 -17.5 52.2 112 129 A H - 0 0 96 -2,-0.2 14,-0.5 -78,-0.2 2,-0.2 -0.798 49.2-147.9 -94.4 120.9 45.9 -19.1 55.3 113 130 A A + 0 0 4 -2,-0.6 2,-0.3 12,-0.1 12,-0.2 -0.568 19.6 172.5 -88.6 148.1 45.6 -22.9 55.6 114 131 A A E -B 124 0A 20 10,-1.1 10,-2.4 -2,-0.2 168,-0.2 -0.976 33.4-112.3-150.5 138.5 45.3 -24.7 58.9 115 132 A F E -B 123 0A 4 166,-3.1 8,-0.3 -2,-0.3 2,-0.2 -0.369 31.8-139.1 -69.1 156.1 44.5 -28.4 59.5 116 133 A T - 0 0 13 6,-2.6 6,-0.3 2,-0.1 -1,-0.1 -0.528 24.0-107.2-108.9 179.2 41.3 -29.4 61.1 117 134 A S S S+ 0 0 96 -2,-0.2 6,-0.1 4,-0.1 -2,-0.0 0.328 75.5 129.5 -86.2 4.0 40.3 -32.0 63.7 118 135 A D - 0 0 49 4,-0.2 4,-0.3 1,-0.1 -2,-0.1 -0.333 67.1-122.8 -61.9 142.4 38.7 -34.2 60.9 119 136 A P S S+ 0 0 124 0, 0.0 -1,-0.1 0, 0.0 3,-0.1 0.961 99.7 53.0 -49.6 -66.1 39.9 -37.8 60.9 120 137 A K S S- 0 0 123 1,-0.1 -2,-0.1 11,-0.0 0, 0.0 -0.585 117.3 -85.8 -76.5 135.1 41.2 -37.9 57.4 121 138 A P + 0 0 28 0, 0.0 11,-0.6 0, 0.0 2,-0.3 -0.204 64.5 165.3 -49.2 123.5 43.7 -35.0 56.9 122 139 A T E - C 0 131A 1 -4,-0.3 -6,-2.6 -6,-0.3 2,-0.3 -0.978 21.4-155.2-143.8 142.2 41.7 -32.0 55.9 123 140 A I E -BC 115 130A 0 7,-2.4 7,-2.5 -2,-0.3 2,-0.4 -0.849 6.4-145.9-115.6 161.8 42.5 -28.3 55.9 124 141 A E E -BC 114 129A 84 -10,-2.4 -10,-1.1 -2,-0.3 2,-0.4 -0.985 12.6-177.2-129.5 134.6 40.3 -25.2 56.1 125 142 A V E > S- C 0 128A 3 3,-2.8 3,-1.8 -2,-0.4 -12,-0.1 -0.968 75.9 -20.0-135.4 114.8 41.0 -22.0 54.3 126 143 A S T 3 S- 0 0 106 -14,-0.5 3,-0.1 -2,-0.4 -1,-0.1 0.918 129.5 -47.5 53.3 50.4 38.6 -19.1 54.9 127 144 A G T 3 S+ 0 0 60 1,-0.2 -1,-0.3 0, 0.0 2,-0.3 0.125 117.5 108.7 81.5 -20.3 35.8 -21.3 56.2 128 145 A K E < - C 0 125A 135 -3,-1.8 -3,-2.8 -127,-0.0 2,-0.4 -0.643 59.9-138.0 -94.6 146.9 36.1 -23.8 53.3 129 146 A K E - C 0 124A 76 -2,-0.3 -127,-1.7 -5,-0.2 2,-0.3 -0.836 19.2-178.6-104.9 144.4 37.5 -27.3 53.7 130 147 A Y E +aC 2 123A 27 -7,-2.5 -7,-2.4 -2,-0.4 2,-0.3 -0.979 2.6 179.9-138.5 147.5 39.8 -29.1 51.2 131 148 A T E +aC 3 122A 7 -129,-2.4 -127,-1.4 -2,-0.3 -9,-0.1 -0.903 7.6 172.8-145.1 166.2 41.2 -32.5 51.2 132 149 A A - 0 0 7 -11,-0.6 -127,-0.2 -2,-0.3 -126,-0.1 -0.909 42.8-117.4-168.4 148.2 43.5 -34.8 49.2 133 150 A P S S+ 0 0 79 0, 0.0 2,-0.4 0, 0.0 -127,-0.1 0.638 110.6 43.0 -64.0 -17.2 45.1 -38.2 49.6 134 151 A H S S+ 0 0 45 -129,-0.5 -127,-2.1 -130,-0.2 2,-0.5 -0.968 70.8 179.4-134.5 116.8 48.5 -36.4 49.4 135 152 A I E -eg 7 309B 0 173,-3.0 175,-2.5 -2,-0.4 2,-0.5 -0.977 10.6-158.7-121.7 125.1 49.0 -33.1 51.2 136 153 A L E -eg 8 310B 0 -129,-2.9 -127,-3.2 -2,-0.5 2,-0.6 -0.902 4.9-153.8-105.5 129.8 52.3 -31.2 51.0 137 154 A I E +eg 9 311B 0 173,-2.4 175,-1.6 -2,-0.5 -127,-0.1 -0.928 29.5 154.4-101.1 117.3 53.3 -28.7 53.7 138 155 A A + 0 0 12 -129,-3.1 -126,-0.4 -2,-0.6 -123,-0.3 -0.337 16.7 138.6-138.3 53.4 55.7 -26.2 52.1 139 156 A T - 0 0 32 1,-0.2 -129,-0.1 138,-0.1 -128,-0.1 0.496 42.1-161.0 -80.1 -6.0 55.1 -23.2 54.4 140 157 A G - 0 0 16 172,-0.4 137,-2.8 -130,-0.1 -1,-0.2 -0.175 18.4 -85.8 62.0-147.7 58.8 -22.2 54.7 141 158 A G E -I 276 0C 7 135,-0.3 174,-0.1 137,-0.0 -101,-0.1 -0.632 25.5-133.3-142.2-161.2 60.1 -20.0 57.4 142 159 A M E -I 275 0C 73 133,-2.0 133,-3.3 -2,-0.2 2,-0.1 -0.972 38.7 -73.0-158.7 163.4 60.6 -16.4 58.6 143 160 A P E -I 274 0C 22 0, 0.0 2,-0.3 0, 0.0 131,-0.3 -0.363 44.1-131.2 -66.3 144.8 63.3 -14.2 60.2 144 161 A S - 0 0 39 129,-2.3 128,-0.5 -2,-0.1 129,-0.3 -0.694 23.4-170.2 -94.3 140.2 64.0 -14.8 63.9 145 162 A T - 0 0 73 -2,-0.3 10,-0.1 127,-0.1 2,-0.1 -0.972 27.2-103.3-130.9 148.2 64.1 -11.8 66.3 146 163 A P - 0 0 14 0, 0.0 2,-0.3 0, 0.0 124,-0.0 -0.369 40.0-107.2 -66.2 150.8 65.2 -11.5 69.9 147 164 A H >> - 0 0 136 1,-0.1 4,-2.9 7,-0.1 3,-1.0 -0.635 17.6-129.1 -82.1 136.9 62.6 -11.3 72.6 148 165 A E T 34 S+ 0 0 90 -2,-0.3 -1,-0.1 1,-0.3 6,-0.1 0.776 110.0 62.1 -52.9 -29.4 62.2 -7.9 74.3 149 166 A S T 34 S+ 0 0 111 1,-0.2 -1,-0.3 2,-0.1 -2,-0.0 0.906 112.1 34.4 -67.1 -39.0 62.5 -9.8 77.6 150 167 A Q T <4 S+ 0 0 133 -3,-1.0 -2,-0.2 1,-0.3 -1,-0.2 0.860 135.1 23.5 -84.1 -36.9 66.0 -10.9 76.7 151 168 A I S >< S- 0 0 13 -4,-2.9 3,-1.9 85,-0.0 -1,-0.3 -0.890 82.6-140.0-132.7 100.0 67.1 -7.8 74.8 152 169 A P T 3 S+ 0 0 57 0, 0.0 85,-2.6 0, 0.0 -3,-0.1 -0.378 90.2 18.4 -59.0 131.3 65.2 -4.6 75.7 153 170 A G T > S+ 0 0 10 83,-0.2 3,-2.0 -2,-0.1 4,-0.2 0.560 78.6 134.2 85.1 7.6 64.5 -2.7 72.5 154 171 A A G X + 0 0 1 -3,-1.9 3,-2.2 1,-0.3 116,-0.1 0.871 64.2 68.0 -57.1 -34.9 65.1 -5.6 70.1 155 172 A S G 3 S+ 0 0 91 1,-0.3 -1,-0.3 -4,-0.2 -8,-0.0 0.508 84.5 72.2 -64.8 -4.4 61.9 -4.6 68.2 156 173 A L G < S+ 0 0 76 -3,-2.0 112,-0.3 2,-0.1 -1,-0.3 0.599 87.7 77.4 -83.8 -14.6 63.6 -1.4 67.1 157 174 A G S < S- 0 0 11 -3,-2.2 112,-0.2 -4,-0.2 2,-0.2 -0.570 75.2-136.4 -92.8 162.5 65.8 -3.5 64.7 158 175 A I B -j 269 0D 50 110,-3.2 112,-3.0 -2,-0.2 2,-0.2 -0.581 8.3-136.4-110.4 171.4 64.7 -4.9 61.4 159 176 A T > - 0 0 21 110,-0.2 4,-1.7 -2,-0.2 3,-0.3 -0.576 45.6 -80.7-114.5-173.8 65.2 -8.3 59.7 160 177 A S H > S+ 0 0 14 110,-0.4 4,-1.3 1,-0.2 111,-0.1 0.826 130.7 60.6 -60.5 -28.3 66.1 -9.1 56.1 161 178 A D H >4 S+ 0 0 57 1,-0.2 3,-0.6 2,-0.2 -1,-0.2 0.945 105.5 47.0 -61.8 -48.3 62.4 -8.6 55.2 162 179 A G H >> S+ 0 0 18 -3,-0.3 3,-1.8 1,-0.2 4,-0.8 0.833 100.9 67.1 -62.8 -33.1 62.7 -5.0 56.4 163 180 A F H >< S+ 0 0 0 -4,-1.7 3,-0.9 1,-0.3 -1,-0.2 0.885 98.7 52.5 -54.8 -38.9 65.9 -4.7 54.4 164 181 A F T << S+ 0 0 17 -4,-1.3 -1,-0.3 -3,-0.6 -2,-0.2 0.503 105.6 54.7 -79.6 -0.6 63.8 -5.0 51.2 165 182 A Q T <4 S+ 0 0 148 -3,-1.8 -1,-0.2 -4,-0.2 -2,-0.2 0.508 77.0 119.5-104.2 -11.0 61.5 -2.3 52.3 166 183 A L << - 0 0 37 -3,-0.9 3,-0.1 -4,-0.8 -3,-0.0 -0.342 40.1-173.7 -58.0 130.9 64.2 0.3 52.9 167 184 A E + 0 0 102 1,-0.1 2,-0.3 -2,-0.1 -1,-0.2 0.520 69.6 37.7-104.2 -7.2 63.6 3.3 50.6 168 185 A E S S- 0 0 141 -89,-0.1 -1,-0.1 -88,-0.1 -90,-0.1 -0.960 91.7-101.8-140.5 151.7 66.9 5.1 51.4 169 186 A L - 0 0 51 -2,-0.3 2,-0.1 23,-0.1 -90,-0.0 -0.670 43.2-122.1 -74.8 123.8 70.4 3.9 52.1 170 187 A P - 0 0 14 0, 0.0 3,-0.2 0, 0.0 25,-0.1 -0.392 11.2-143.5 -67.4 144.3 71.0 3.9 55.9 171 188 A G S S+ 0 0 46 1,-0.3 24,-2.7 23,-0.2 2,-0.4 0.896 86.3 21.3 -75.9 -38.5 73.9 6.1 56.9 172 189 A R E S-k 195 0D 44 22,-0.2 95,-2.0 2,-0.0 94,-1.6 -0.996 76.2-178.7-132.2 124.1 75.1 3.9 59.8 173 190 A S E -kl 196 267D 0 22,-2.5 24,-2.3 -2,-0.4 2,-0.5 -0.976 17.0-164.6-133.2 145.6 74.2 0.3 60.0 174 191 A V E -kl 197 268D 0 93,-2.7 95,-3.0 -2,-0.4 2,-0.5 -0.994 10.0-164.8-124.9 119.2 74.8 -2.6 62.4 175 192 A I E -kl 198 269D 0 22,-2.6 24,-3.4 -2,-0.5 2,-0.6 -0.919 6.7-155.8-104.6 130.4 74.2 -6.1 61.3 176 193 A V E +kl 199 270D 15 93,-3.0 95,-3.1 -2,-0.5 2,-0.2 -0.940 52.2 57.2-111.7 118.0 74.0 -8.7 64.0 177 194 A G - 0 0 9 22,-2.3 95,-0.2 -2,-0.6 -2,-0.1 -0.584 59.3-133.8 144.9 161.6 74.7 -12.3 63.0 178 195 A A + 0 0 31 -2,-0.2 28,-3.3 93,-0.2 29,-0.2 0.259 67.2 99.9-129.1 8.8 77.4 -14.4 61.4 179 196 A G S > S- 0 0 38 92,-0.6 4,-2.2 26,-0.2 3,-0.3 -0.287 90.9 -84.3 -86.9-177.9 75.6 -16.6 58.8 180 197 A Y H > S+ 0 0 82 1,-0.2 4,-2.5 2,-0.2 5,-0.2 0.823 126.0 55.6 -60.3 -34.1 75.5 -16.0 55.0 181 198 A I H > S+ 0 0 40 2,-0.2 4,-2.6 1,-0.2 -1,-0.2 0.937 109.8 47.5 -64.5 -41.9 72.5 -13.6 55.1 182 199 A A H > S+ 0 0 0 89,-0.3 4,-2.5 -3,-0.3 5,-0.2 0.930 112.7 48.5 -62.6 -48.8 74.4 -11.4 57.6 183 200 A V H X S+ 0 0 1 -4,-2.2 4,-2.1 1,-0.2 -1,-0.2 0.885 112.8 48.5 -59.7 -43.0 77.5 -11.4 55.5 184 201 A E H X S+ 0 0 3 -4,-2.5 4,-2.0 2,-0.2 -2,-0.2 0.929 112.4 46.6 -64.8 -46.9 75.5 -10.6 52.3 185 202 A M H X S+ 0 0 4 -4,-2.6 4,-2.5 1,-0.2 5,-0.3 0.921 113.0 49.8 -61.2 -47.4 73.6 -7.7 53.8 186 203 A A H X S+ 0 0 0 -4,-2.5 4,-2.4 1,-0.2 5,-0.2 0.912 111.2 49.9 -58.0 -43.8 76.8 -6.3 55.4 187 204 A G H X S+ 0 0 7 -4,-2.1 4,-1.8 -5,-0.2 -1,-0.2 0.853 113.3 44.3 -64.6 -38.3 78.6 -6.5 52.0 188 205 A I H X S+ 0 0 0 -4,-2.0 4,-2.2 2,-0.2 -2,-0.2 0.938 115.3 47.5 -71.8 -46.7 75.9 -4.8 50.0 189 206 A L H <>S+ 0 0 0 -4,-2.5 5,-2.8 1,-0.2 4,-0.4 0.929 115.2 46.1 -61.2 -43.1 75.3 -2.0 52.6 190 207 A S H ><5S+ 0 0 23 -4,-2.4 3,-1.3 -5,-0.3 -1,-0.2 0.916 111.6 50.1 -65.8 -45.8 79.0 -1.3 52.9 191 208 A A H 3<5S+ 0 0 21 -4,-1.8 -1,-0.2 1,-0.3 -2,-0.2 0.873 110.0 52.5 -60.6 -38.3 79.7 -1.4 49.1 192 209 A L T 3<5S- 0 0 11 -4,-2.2 -1,-0.3 -5,-0.1 -2,-0.2 0.518 129.9 -91.4 -79.5 -3.4 76.8 1.1 48.6 193 210 A G T < 5S+ 0 0 57 -3,-1.3 2,-0.2 -4,-0.4 -3,-0.2 0.471 75.5 138.4 113.5 -0.6 78.2 3.5 51.1 194 211 A S < - 0 0 5 -5,-2.8 2,-1.2 -6,-0.2 -1,-0.3 -0.586 60.4-118.1 -80.1 139.9 76.7 2.7 54.6 195 212 A K E -k 172 0D 139 -24,-2.7 -22,-2.5 -2,-0.2 2,-0.4 -0.703 50.4-163.5 -75.9 103.8 79.1 2.9 57.5 196 213 A T E -k 173 0D 3 -2,-1.2 31,-2.6 29,-0.3 2,-0.4 -0.802 28.1-178.1-110.0 136.7 78.8 -0.7 58.4 197 214 A S E -km 174 227D 0 -24,-2.3 -22,-2.6 -2,-0.4 2,-0.5 -0.942 13.3-155.2-121.8 141.0 79.5 -2.9 61.5 198 215 A L E -km 175 228D 0 29,-2.7 31,-2.7 -2,-0.4 2,-0.6 -0.984 12.1-153.3-118.8 114.3 78.9 -6.7 61.6 199 216 A M E +km 176 229D 2 -24,-3.4 -22,-2.3 -2,-0.5 2,-0.3 -0.829 19.2 174.9 -94.6 117.9 78.5 -8.0 65.1 200 217 A I - 0 0 1 29,-2.3 32,-2.6 -2,-0.6 5,-0.1 -0.917 35.9-134.5-124.2 150.2 79.4 -11.6 65.7 201 218 A R S S+ 0 0 162 -2,-0.3 2,-0.1 30,-0.3 50,-0.1 0.660 90.9 26.5 -73.5 -22.9 79.5 -13.8 68.8 202 219 A H S S- 0 0 69 2,-0.2 29,-2.7 29,-0.1 30,-0.3 -0.223 98.7 -85.4-116.5-145.6 82.9 -15.3 67.9 203 220 A D S S+ 0 0 62 27,-0.2 2,-0.3 -2,-0.1 27,-0.1 0.512 100.0 40.6-107.7 -10.1 85.9 -14.3 65.9 204 221 A K S S- 0 0 69 14,-0.0 3,-0.3 13,-0.0 -2,-0.2 -0.960 70.4-125.6-139.8 155.0 84.9 -15.4 62.4 205 222 A V S S+ 0 0 0 9,-0.6 13,-0.2 -2,-0.3 -26,-0.2 -0.512 88.7 26.2 -92.7 163.9 81.8 -15.4 60.1 206 223 A L > + 0 0 3 -28,-3.3 3,-1.8 -2,-0.2 -1,-0.2 0.896 68.2 175.5 50.3 53.2 80.4 -18.5 58.4 207 224 A R T 3 S+ 0 0 143 -3,-0.3 -1,-0.1 1,-0.3 7,-0.1 0.641 71.3 61.4 -65.7 -15.3 81.8 -20.8 61.1 208 225 A S T 3 S+ 0 0 99 2,-0.1 -1,-0.3 6,-0.0 2,-0.2 0.508 91.6 84.9 -86.5 -7.2 80.1 -23.9 59.5 209 226 A F S < S- 0 0 39 -3,-1.8 5,-0.2 1,-0.2 208,-0.0 -0.472 103.4 -68.8 -87.6 166.1 82.0 -23.5 56.3 210 227 A D >> - 0 0 3 1,-0.2 4,-1.9 -2,-0.2 3,-0.7 -0.198 50.2-117.2 -52.9 145.8 85.5 -24.8 55.7 211 228 A S H 3> S+ 0 0 55 1,-0.2 4,-2.0 2,-0.2 5,-0.3 0.762 113.5 62.0 -60.9 -27.9 87.9 -22.9 57.9 212 229 A M H 3> S+ 0 0 34 1,-0.2 4,-2.4 2,-0.2 -1,-0.2 0.925 109.2 44.0 -63.4 -38.2 89.8 -21.6 54.9 213 230 A I H <> S+ 0 0 0 -3,-0.7 4,-2.8 2,-0.2 5,-0.2 0.896 111.7 49.0 -73.6 -44.7 86.6 -19.8 53.9 214 231 A S H X S+ 0 0 8 -4,-1.9 4,-1.9 2,-0.2 -9,-0.6 0.932 116.6 45.5 -62.8 -38.7 85.5 -18.5 57.3 215 232 A T H X S+ 0 0 42 -4,-2.0 4,-2.0 -5,-0.2 -2,-0.2 0.971 116.8 42.2 -67.9 -52.1 89.0 -17.1 57.8 216 233 A N H X S+ 0 0 8 -4,-2.4 4,-2.5 -5,-0.3 5,-0.2 0.883 113.5 53.1 -63.9 -37.2 89.3 -15.6 54.3 217 234 A C H X S+ 0 0 1 -4,-2.8 4,-1.9 2,-0.2 -1,-0.2 0.904 107.6 50.6 -67.7 -38.6 85.8 -14.2 54.3 218 235 A T H X S+ 0 0 4 -4,-1.9 4,-1.7 -5,-0.2 -1,-0.2 0.912 112.5 47.4 -66.0 -40.3 86.3 -12.4 57.6 219 236 A E H X S+ 0 0 82 -4,-2.0 4,-2.9 2,-0.2 -2,-0.2 0.913 109.5 52.2 -66.3 -41.6 89.5 -10.8 56.3 220 237 A E H X S+ 0 0 11 -4,-2.5 4,-1.6 1,-0.2 -1,-0.2 0.879 107.5 53.8 -63.4 -34.5 87.9 -9.7 53.0 221 238 A L H <>S+ 0 0 11 -4,-1.9 5,-2.6 -5,-0.2 -1,-0.2 0.938 112.0 43.4 -62.9 -48.0 85.1 -8.1 54.9 222 239 A E H ><5S+ 0 0 83 -4,-1.7 3,-1.7 1,-0.2 -2,-0.2 0.910 111.8 53.5 -64.5 -41.5 87.6 -6.1 57.0 223 240 A N H 3<5S+ 0 0 121 -4,-2.9 -1,-0.2 1,-0.3 -2,-0.2 0.770 107.2 53.2 -62.6 -31.4 89.7 -5.3 53.9 224 241 A A T 3<5S- 0 0 62 -4,-1.6 -1,-0.3 -5,-0.2 -2,-0.2 0.321 127.7 -95.9 -86.8 2.9 86.5 -3.9 52.2 225 242 A G T < 5S+ 0 0 47 -3,-1.7 2,-0.5 1,-0.3 -29,-0.3 0.548 76.8 138.6 98.4 5.5 85.7 -1.6 55.1 226 243 A V < - 0 0 5 -5,-2.6 2,-1.0 -6,-0.2 -1,-0.3 -0.747 50.8-134.2 -86.3 128.5 83.2 -3.6 57.2 227 244 A E E -m 197 0D 99 -31,-2.6 -29,-2.7 -2,-0.5 2,-0.7 -0.725 17.8-157.4 -84.5 107.0 83.9 -3.3 60.8 228 245 A V E -m 198 0D 13 -2,-1.0 2,-0.9 -31,-0.2 -29,-0.2 -0.767 0.7-159.0 -89.6 114.1 83.7 -6.8 62.3 229 246 A L E > -m 199 0D 23 -31,-2.7 -29,-2.3 -2,-0.7 3,-0.6 -0.816 17.8-155.2 -93.2 100.8 82.9 -6.6 66.0 230 247 A K T 3 + 0 0 73 -2,-0.9 -27,-0.2 1,-0.2 -29,-0.2 -0.353 64.8 8.1 -81.3 154.2 84.1 -10.0 67.4 231 248 A F T 3 S+ 0 0 51 -29,-2.7 20,-2.6 1,-0.2 2,-0.3 0.809 100.9 131.3 47.8 39.8 82.9 -11.8 70.6 232 249 A S E < +N 250 0E 3 -32,-2.6 2,-0.3 -3,-0.6 18,-0.2 -0.871 33.1 175.4-125.2 150.9 80.2 -9.2 70.9 233 250 A Q E -N 249 0E 82 16,-1.8 16,-2.3 -2,-0.3 2,-0.3 -0.983 37.1 -97.5-150.0 154.4 76.4 -9.2 71.4 234 251 A V E +N 248 0E 7 -2,-0.3 14,-0.3 14,-0.2 3,-0.1 -0.555 28.2 179.8 -73.4 131.9 73.7 -6.7 72.0 235 252 A K E - 0 0 96 12,-3.4 2,-0.3 1,-0.5 13,-0.2 0.767 69.9 -22.3 -98.4 -40.9 72.7 -6.1 75.6 236 253 A E E -N 247 0E 66 11,-1.5 11,-3.1 -85,-0.2 -1,-0.5 -0.985 52.6-143.5-165.6 160.2 70.0 -3.5 74.7 237 254 A V E -N 246 0E 4 -85,-2.6 2,-0.3 -2,-0.3 9,-0.2 -0.987 18.0-177.2-130.1 138.7 68.9 -1.1 72.1 238 255 A K E -N 245 0E 106 7,-2.1 7,-2.6 -2,-0.4 2,-0.5 -0.991 28.6-118.9-140.5 148.0 67.3 2.3 72.7 239 256 A K E -N 244 0E 131 -2,-0.3 5,-0.2 5,-0.2 2,-0.2 -0.765 36.7-173.9 -83.3 118.5 65.8 5.1 70.5 240 257 A T E > -N 243 0E 35 3,-3.4 3,-0.7 -2,-0.5 5,-0.0 -0.437 45.5 -84.5-102.3-174.3 67.7 8.3 70.9 241 258 A L T 3 S+ 0 0 179 1,-0.3 2,-0.1 -2,-0.2 3,-0.1 0.762 125.9 24.5 -61.5 -24.9 67.0 11.8 69.5 242 259 A S T 3 S- 0 0 80 1,-0.3 -1,-0.3 23,-0.0 2,-0.2 -0.572 128.4 -40.2-145.2 75.7 68.8 10.8 66.4 243 260 A G E < S-N 240 0E 8 -3,-0.7 -3,-3.4 21,-0.1 -1,-0.3 -0.540 85.0 -45.4 104.0-170.5 68.9 7.1 65.7 244 261 A L E -NO 239 265E 11 21,-3.1 21,-2.5 -5,-0.2 2,-0.5 -0.619 39.0-144.8-100.4 156.9 69.4 4.1 67.9 245 262 A E E -N 238 0E 47 -7,-2.6 -7,-2.1 -2,-0.2 2,-0.5 -0.997 16.7-157.7-122.9 119.9 72.0 3.5 70.6 246 263 A V E -NO 237 262E 0 16,-3.0 16,-3.5 -2,-0.5 2,-0.5 -0.897 2.7-157.7-104.6 123.0 73.2 -0.0 70.8 247 264 A S E +NO 236 261E 9 -11,-3.1 -12,-3.4 -2,-0.5 -11,-1.5 -0.864 21.3 177.0 -98.4 129.1 74.7 -1.3 74.0 248 265 A M E -NO 234 260E 10 12,-3.1 12,-2.9 -2,-0.5 2,-0.4 -0.945 25.4-141.8-134.1 154.3 76.9 -4.3 73.5 249 266 A V E -NO 233 259E 43 -16,-2.3 -16,-1.8 -2,-0.3 2,-0.5 -0.955 12.5-161.1-112.9 131.0 79.2 -6.4 75.6 250 267 A T E +NO 232 258E 26 8,-2.7 8,-2.1 -2,-0.4 2,-0.5 -0.979 9.8 179.9-113.5 117.4 82.4 -7.7 74.1 251 268 A A - 0 0 49 -20,-2.6 5,-0.1 -2,-0.5 -20,-0.0 -0.786 3.4-174.9-123.0 84.5 83.9 -10.7 75.9 252 269 A V > - 0 0 48 -2,-0.5 3,-1.6 4,-0.3 -2,-0.1 -0.670 40.4-102.7 -77.0 128.1 87.1 -11.7 74.2 253 270 A P T 3 S+ 0 0 93 0, 0.0 3,-0.1 0, 0.0 -1,-0.1 -0.318 108.2 24.8 -54.3 132.2 88.4 -14.9 75.9 254 271 A G T 3 S+ 0 0 88 1,-0.4 2,-0.3 -3,-0.0 -2,-0.0 0.590 112.0 81.3 88.5 8.9 91.2 -14.0 78.3 255 272 A R S < S- 0 0 194 -3,-1.6 -1,-0.4 3,-0.0 3,-0.0 -0.859 87.2 -96.1-136.2 168.0 90.1 -10.4 78.8 256 273 A L - 0 0 155 -2,-0.3 -4,-0.3 -3,-0.1 2,-0.1 -0.671 49.3-101.0 -83.3 145.2 87.6 -8.8 81.0 257 274 A P - 0 0 87 0, 0.0 2,-0.4 0, 0.0 -6,-0.2 -0.377 37.6-157.3 -61.8 144.8 84.2 -8.0 79.4 258 275 A V E -O 250 0E 77 -8,-2.1 -8,-2.7 -2,-0.1 2,-0.5 -0.972 7.7-141.2-130.3 136.6 83.7 -4.5 78.3 259 276 A M E -O 249 0E 104 -2,-0.4 2,-0.3 -10,-0.2 -10,-0.2 -0.877 23.9-177.8 -97.9 135.0 80.4 -2.7 77.6 260 277 A T E -O 248 0E 56 -12,-2.9 -12,-3.1 -2,-0.5 2,-0.5 -0.975 20.4-141.5-134.8 150.5 80.2 -0.3 74.7 261 278 A M E -O 247 0E 89 -2,-0.3 -14,-0.2 -14,-0.2 -2,-0.0 -0.940 7.8-158.8-113.9 123.6 77.6 2.0 73.3 262 279 A I E -O 246 0E 13 -16,-3.5 -16,-3.0 -2,-0.5 3,-0.3 -0.920 23.8-164.9-103.0 110.5 77.2 2.3 69.5 263 280 A P E + 0 0 60 0, 0.0 -18,-0.2 0, 0.0 -19,-0.1 -0.531 54.5 25.6 -96.6 167.3 75.4 5.7 68.9 264 281 A D E S+ 0 0 97 1,-0.2 2,-0.5 -2,-0.2 -19,-0.2 0.862 71.8 167.9 52.8 44.4 73.6 7.2 66.0 265 282 A V E -O 244 0E 0 -21,-2.5 -21,-3.1 -3,-0.3 -1,-0.2 -0.765 20.7-173.0 -89.7 128.4 72.7 4.0 64.4 266 283 A D S S+ 0 0 92 -94,-1.6 2,-0.4 -2,-0.5 -93,-0.2 0.825 73.1 27.4 -86.9 -36.6 70.2 4.4 61.6 267 284 A C E - l 0 173D 8 -95,-2.0 -93,-2.7 -23,-0.1 2,-0.6 -0.982 55.6-173.8-137.3 122.8 69.7 0.7 61.0 268 285 A L E - l 0 174D 2 -2,-0.4 -110,-3.2 -112,-0.3 2,-0.6 -0.977 17.5-168.2-111.2 118.0 70.0 -2.3 63.3 269 286 A L E -jl 158 175D 0 -95,-3.0 -93,-3.0 -2,-0.6 2,-0.6 -0.938 11.4-150.3-117.7 116.1 69.5 -5.5 61.3 270 287 A W E + l 0 176D 9 -112,-3.0 -110,-0.4 -2,-0.6 -93,-0.2 -0.716 25.3 163.2 -83.2 120.2 69.0 -8.9 63.0 271 288 A A + 0 0 17 -95,-3.1 -92,-0.6 -2,-0.6 -89,-0.3 -0.420 32.2 124.0-134.0 56.1 70.3 -11.7 60.9 272 289 A I S S- 0 0 82 -128,-0.5 2,-0.3 1,-0.2 -1,-0.1 0.482 73.0 -46.9 -97.8 -8.0 70.5 -14.3 63.7 273 290 A G - 0 0 38 -129,-0.3 -129,-2.3 -3,-0.1 2,-0.4 -0.929 47.3-100.8 160.1 176.0 68.4 -17.1 62.3 274 291 A R E -I 143 0C 57 -2,-0.3 -3,-0.0 -131,-0.3 -129,-0.0 -0.977 24.8-152.6-128.2 143.0 65.2 -18.3 60.6 275 292 A V E -I 142 0C 53 -133,-3.3 -133,-2.0 -2,-0.4 19,-0.1 -0.903 25.5-108.9-120.5 140.5 62.2 -19.9 62.3 276 293 A P E -I 141 0C 9 0, 0.0 2,-1.3 0, 0.0 3,-0.4 -0.377 22.5-124.0 -73.7 150.4 59.8 -22.4 60.6 277 294 A N S S+ 0 0 58 -137,-2.8 -138,-0.1 1,-0.2 38,-0.1 -0.709 76.0 106.1 -91.6 84.2 56.3 -21.3 59.7 278 295 A T > > + 0 0 15 -2,-1.3 3,-1.4 2,-0.0 5,-0.5 0.471 42.9 93.3-137.1 -10.5 54.3 -24.0 61.6 279 296 A K G > 5S+ 0 0 175 -3,-0.4 3,-0.6 1,-0.3 4,-0.1 0.879 92.8 42.4 -58.5 -37.5 52.7 -22.4 64.6 280 297 A D G 3 5S+ 0 0 91 1,-0.2 -1,-0.3 2,-0.1 -2,-0.0 0.276 91.5 83.7 -97.1 12.3 49.5 -21.5 62.9 281 298 A L G < 5S- 0 0 6 -3,-1.4 -166,-3.1 -167,-0.1 -1,-0.2 0.571 90.4-129.8 -86.6 -14.3 48.9 -24.8 61.0 282 299 A S T X 5 + 0 0 32 -3,-0.6 3,-1.6 -4,-0.3 4,-0.3 0.887 46.3 162.6 63.5 40.2 47.3 -26.6 63.9 283 300 A L G >>X + 0 0 10 -5,-0.5 3,-2.0 1,-0.3 5,-1.7 0.824 65.0 69.8 -57.0 -35.2 49.7 -29.5 63.4 284 301 A N G 345S+ 0 0 130 1,-0.3 3,-0.4 2,-0.2 -1,-0.3 0.784 84.6 69.8 -55.6 -29.2 48.9 -30.7 66.9 285 302 A K G <45S+ 0 0 104 -3,-1.6 -1,-0.3 1,-0.2 -2,-0.2 0.737 111.2 30.2 -63.3 -23.9 45.4 -31.6 65.6 286 303 A L T <45S- 0 0 35 -3,-2.0 -1,-0.2 -4,-0.3 -2,-0.2 0.413 111.4-115.1-112.9 -2.6 46.8 -34.5 63.6 287 304 A G T <5 + 0 0 43 -4,-0.9 2,-0.4 -3,-0.4 -3,-0.2 0.831 48.6 175.5 72.0 32.9 49.8 -35.2 65.9 288 305 A I < - 0 0 10 -5,-1.7 2,-0.2 1,-0.1 -1,-0.2 -0.586 31.4-118.0 -75.4 123.5 52.4 -34.2 63.2 289 306 A Q + 0 0 104 -2,-0.4 8,-2.4 8,-0.2 2,-0.3 -0.459 38.4 169.9 -66.0 135.2 55.9 -34.4 64.8 290 307 A T B -P 296 0F 61 6,-0.3 6,-0.2 -2,-0.2 2,-0.2 -0.818 30.9-119.1-135.7 163.2 58.0 -31.3 65.0 291 308 A D > - 0 0 57 4,-1.6 3,-1.7 -2,-0.3 6,-0.0 -0.417 48.2 -84.9 -91.6-174.6 61.3 -30.7 66.9 292 309 A D T 3 S+ 0 0 153 1,-0.3 -1,-0.0 -2,-0.2 -2,-0.0 0.694 128.8 56.8 -69.9 -15.1 61.5 -28.1 69.6 293 310 A K T 3 S- 0 0 140 2,-0.1 -1,-0.3 -18,-0.0 0, 0.0 0.446 121.8-104.1 -89.3 -3.8 62.1 -25.2 67.1 294 311 A G S < S+ 0 0 16 -3,-1.7 2,-0.2 1,-0.3 -2,-0.1 0.539 70.5 147.4 94.9 4.8 58.9 -26.1 65.3 295 312 A H - 0 0 34 21,-0.1 -4,-1.6 1,-0.1 2,-0.4 -0.534 52.1-116.0 -73.3 145.8 60.4 -27.8 62.3 296 313 A I B -P 290 0F 2 19,-1.8 2,-0.4 -6,-0.2 -6,-0.3 -0.650 27.2-131.2 -84.1 132.7 58.4 -30.6 60.8 297 314 A I + 0 0 64 -8,-2.4 2,-0.3 -2,-0.4 8,-0.3 -0.713 34.0 170.4 -84.7 133.9 60.2 -33.9 61.0 298 315 A V - 0 0 36 -2,-0.4 6,-0.2 18,-0.2 2,-0.1 -0.907 27.7-125.5-138.7 162.0 60.4 -36.0 57.8 299 316 A D > - 0 0 73 4,-1.7 3,-1.8 -2,-0.3 6,-0.0 -0.230 52.4 -76.4 -92.1-168.1 62.1 -39.1 56.6 300 317 A E T 3 S+ 0 0 123 1,-0.3 45,-0.4 2,-0.1 -1,-0.0 0.638 133.4 52.6 -67.3 -15.8 64.4 -39.4 53.5 301 318 A F T 3 S- 0 0 47 43,-0.1 -1,-0.3 2,-0.1 3,-0.1 0.261 120.0-107.7-102.4 8.7 61.3 -39.4 51.3 302 319 A Q S < S+ 0 0 6 -3,-1.8 9,-2.0 1,-0.3 2,-0.2 0.595 70.2 148.7 74.6 14.6 59.9 -36.3 52.9 303 320 A N B -H 310 0B 38 7,-0.2 -4,-1.7 1,-0.1 -1,-0.3 -0.534 37.3-146.6 -75.6 142.1 57.2 -38.2 54.7 304 321 A T - 0 0 16 5,-2.2 -6,-0.1 2,-0.5 -5,-0.1 -0.249 40.5 -89.7 -90.9-168.8 56.0 -36.9 58.0 305 322 A N S S+ 0 0 79 -8,-0.3 2,-0.5 -16,-0.1 -7,-0.1 0.630 112.4 75.5 -79.9 -9.0 54.9 -39.3 60.8 306 323 A V S > S- 0 0 30 3,-0.2 3,-1.6 -17,-0.1 -2,-0.5 -0.890 90.6-115.3-106.7 126.3 51.3 -39.1 59.4 307 324 A K T 3 S+ 0 0 201 -2,-0.5 3,-0.1 1,-0.2 -2,-0.1 -0.317 99.0 21.5 -59.8 134.4 50.4 -41.0 56.1 308 325 A G T 3 S+ 0 0 17 1,-0.2 -173,-3.0 -4,-0.1 2,-0.4 0.455 103.5 101.5 86.4 2.3 49.5 -38.8 53.2 309 326 A I E < +g 135 0B 0 -3,-1.6 -5,-2.2 -175,-0.2 2,-0.3 -0.980 45.1 170.8-124.4 126.9 51.3 -35.8 54.7 310 327 A Y E -gH 136 303B 13 -175,-2.5 -173,-2.4 -2,-0.4 2,-0.3 -0.831 15.6-156.3-128.7 168.7 54.7 -34.6 53.5 311 328 A A E +g 137 0B 0 -9,-2.0 2,-0.3 -2,-0.3 -173,-0.2 -0.989 13.5 171.0-150.3 136.0 56.9 -31.6 54.0 312 329 A V > + 0 0 1 -175,-1.6 3,-0.5 -2,-0.3 -172,-0.4 -0.945 41.9 23.5-139.9 162.8 59.7 -30.1 52.0 313 330 A G G > >S- 0 0 13 -2,-0.3 3,-2.0 1,-0.2 5,-0.5 -0.320 110.6 -17.1 87.2-162.0 61.8 -26.9 52.1 314 331 A D G > 5S+ 0 0 34 1,-0.3 3,-2.1 2,-0.2 -1,-0.2 0.760 120.6 72.6 -54.9 -30.4 62.7 -24.5 54.8 315 332 A V G < 5S+ 0 0 0 -3,-0.5 -19,-1.8 1,-0.3 -1,-0.3 0.734 94.7 54.4 -60.5 -21.4 59.9 -25.8 57.1 316 333 A C G < 5S- 0 0 20 -3,-2.0 -1,-0.3 -21,-0.2 -2,-0.2 0.454 106.0-133.6 -89.7 -9.0 62.0 -29.0 57.6 317 334 A G T < 5 + 0 0 29 -3,-2.1 2,-0.4 -4,-0.3 3,-0.2 0.578 64.7 111.9 69.5 13.2 64.9 -26.9 58.7 318 335 A K S - 0 0 42 -2,-2.3 4,-1.7 -3,-0.2 3,-0.4 -0.972 66.2-125.9-133.8 150.4 68.1 -23.2 49.8 322 339 A T H > S+ 0 0 35 -2,-0.3 4,-2.5 1,-0.2 5,-0.2 0.924 109.1 51.6 -63.2 -48.2 65.6 -22.6 47.0 323 340 A P H > S+ 0 0 91 0, 0.0 4,-2.4 0, 0.0 -1,-0.2 0.769 108.1 54.6 -64.2 -22.7 67.0 -25.3 44.6 324 341 A V H > S+ 0 0 9 -3,-0.4 4,-2.7 2,-0.2 5,-0.3 0.914 108.7 46.4 -72.7 -44.9 66.8 -27.9 47.5 325 342 A A H X S+ 0 0 6 -4,-1.7 4,-2.4 2,-0.2 5,-0.2 0.937 115.6 48.3 -61.5 -44.5 63.1 -27.2 48.1 326 343 A I H X S+ 0 0 44 -4,-2.5 4,-2.4 2,-0.2 -2,-0.2 0.941 113.2 45.2 -61.4 -50.3 62.5 -27.4 44.3 327 344 A A H X S+ 0 0 31 -4,-2.4 4,-2.5 1,-0.2 5,-0.2 0.915 115.7 46.7 -63.4 -43.2 64.5 -30.7 43.8 328 345 A A H X S+ 0 0 1 -4,-2.7 4,-1.8 2,-0.2 -1,-0.2 0.881 111.8 52.5 -64.1 -40.8 62.8 -32.3 46.8 329 346 A G H X S+ 0 0 0 -4,-2.4 4,-1.7 -5,-0.3 -2,-0.2 0.899 113.3 43.2 -62.8 -42.5 59.4 -31.1 45.6 330 347 A R H X S+ 0 0 90 -4,-2.4 4,-2.0 2,-0.2 -2,-0.2 0.883 111.1 52.8 -70.8 -43.2 59.9 -32.6 42.2 331 348 A K H X S+ 0 0 92 -4,-2.5 4,-1.5 1,-0.2 -1,-0.2 0.850 109.8 51.2 -60.4 -35.0 61.3 -35.8 43.4 332 349 A L H X S+ 0 0 4 -4,-1.8 4,-2.6 2,-0.2 5,-0.3 0.909 106.1 53.5 -68.9 -43.2 58.3 -36.2 45.6 333 350 A A H X S+ 0 0 0 -4,-1.7 4,-2.7 1,-0.2 5,-0.5 0.907 109.7 49.0 -58.3 -42.8 55.9 -35.5 42.7 334 351 A H H X S+ 0 0 32 -4,-2.0 6,-1.7 3,-0.2 4,-1.3 0.866 110.8 50.8 -65.2 -34.1 57.6 -38.3 40.7 335 352 A R H < S+ 0 0 42 -4,-1.5 4,-0.3 4,-0.2 -2,-0.2 0.934 119.1 34.8 -69.5 -43.4 57.3 -40.7 43.7 336 353 A L H < S+ 0 0 12 -4,-2.6 -2,-0.2 1,-0.1 -3,-0.2 0.869 131.4 26.9 -79.8 -40.2 53.6 -40.1 44.3 337 354 A F H < S+ 0 0 29 -4,-2.7 -3,-0.2 -5,-0.3 -2,-0.2 0.557 129.2 37.3-105.0 -11.4 52.3 -39.6 40.8 338 355 A E S < S- 0 0 79 -4,-1.3 -3,-0.2 -5,-0.5 -2,-0.1 0.395 100.9-128.0-115.1 -0.2 54.8 -41.6 38.7 339 356 A Y + 0 0 189 -4,-0.3 2,-1.4 -6,-0.3 -4,-0.2 0.757 53.7 152.1 62.3 25.9 55.1 -44.3 41.3 340 357 A K > - 0 0 96 -6,-1.7 3,-2.0 1,-0.2 -1,-0.2 -0.732 23.4-173.2 -85.7 89.1 58.9 -44.1 41.3 341 358 A E T 3 S+ 0 0 166 -2,-1.4 -1,-0.2 1,-0.3 -6,-0.1 0.642 79.2 56.1 -62.5 -14.6 59.3 -45.3 44.9 342 359 A D T 3 S+ 0 0 125 -3,-0.1 2,-0.6 -7,-0.0 -1,-0.3 0.341 77.7 121.4 -96.0 2.2 63.1 -44.7 44.9 343 360 A S < + 0 0 9 -3,-2.0 2,-0.3 -12,-0.1 -8,-0.1 -0.597 35.2 122.7 -72.8 113.1 62.5 -41.0 44.0 344 361 A K - 0 0 79 -2,-0.6 2,-0.3 -10,-0.0 -43,-0.1 -0.967 61.0 -96.4-162.8 159.3 64.1 -38.8 46.7 345 362 A L - 0 0 27 -45,-0.4 2,-0.7 -2,-0.3 -43,-0.1 -0.668 25.5-136.5 -88.0 139.2 66.6 -36.1 47.0 346 363 A D - 0 0 60 -2,-0.3 -18,-0.0 1,-0.1 -1,-0.0 -0.848 12.0-159.7 -91.0 113.8 70.2 -36.9 48.0 347 364 A Y + 0 0 45 -2,-0.7 3,-0.5 2,-0.0 2,-0.3 0.373 61.6 97.1 -78.3 7.1 71.1 -34.2 50.5 348 365 A N S S+ 0 0 99 1,-0.2 -2,-0.1 15,-0.0 17,-0.0 -0.665 82.6 18.7 -95.0 153.2 74.9 -34.7 50.0 349 366 A N S S+ 0 0 52 -2,-0.3 -1,-0.2 1,-0.2 86,-0.1 0.851 75.9 162.8 59.8 37.9 76.9 -32.6 47.7 350 367 A I - 0 0 39 -3,-0.5 14,-0.5 14,-0.1 2,-0.2 -0.769 32.8-135.0 -86.8 126.2 74.5 -29.8 47.6 351 368 A P E -Q 363 0G 46 0, 0.0 2,-0.3 0, 0.0 12,-0.2 -0.623 21.5-168.4 -88.1 149.2 76.4 -26.7 46.2 352 369 A T E -Q 362 0G 37 10,-2.9 10,-2.5 -2,-0.2 2,-0.4 -0.999 11.8-163.1-138.0 143.3 76.1 -23.2 47.7 353 370 A V E -Q 361 0G 32 -2,-0.3 2,-0.6 8,-0.2 8,-0.2 -0.982 7.5-157.4-124.5 129.5 77.2 -19.7 46.7 354 371 A V E -Q 360 0G 0 6,-2.0 6,-2.9 -2,-0.4 2,-2.0 -0.963 18.2-137.4-105.2 122.0 77.4 -16.9 49.2 355 372 A F + 0 0 34 -2,-0.6 2,-0.1 4,-0.2 -168,-0.1 -0.498 55.3 133.7 -81.1 63.3 77.1 -13.5 47.4 356 373 A S - 0 0 3 -2,-2.0 -172,-0.1 2,-0.2 -139,-0.0 -0.274 69.3 -67.0 -92.6-168.7 79.8 -11.8 49.3 357 374 A H S S+ 0 0 22 1,-0.3 -133,-0.1 -2,-0.1 64,-0.1 -0.950 134.9 18.3-128.2 106.8 82.6 -9.7 47.7 358 375 A P S S- 0 0 4 0, 0.0 -1,-0.3 0, 0.0 -2,-0.2 0.707 114.9-115.1 -72.1 164.4 84.2 -11.7 46.2 359 376 A P - 0 0 4 0, 0.0 61,-2.1 0, 0.0 2,-0.4 -0.263 21.6-133.6 -70.0 157.4 81.6 -14.5 46.1 360 377 A I E -QR 354 419G 0 -6,-2.9 -6,-2.0 59,-0.2 2,-0.4 -0.888 16.7-170.4-112.3 140.7 82.0 -17.9 47.8 361 378 A G E +QR 353 418G 0 57,-2.4 57,-2.2 -2,-0.4 2,-0.3 -0.995 12.5 168.9-129.5 133.6 81.3 -21.2 46.2 362 379 A T E +QR 352 417G 17 -10,-2.5 -10,-2.9 -2,-0.4 2,-0.3 -0.998 10.0 168.9-147.7 143.6 81.2 -24.5 48.2 363 380 A V E -QR 351 416G 2 53,-2.2 53,-2.6 -2,-0.3 2,-0.1 -0.962 52.2 -1.0-151.4 137.1 80.2 -28.1 47.6 364 381 A G E S- R 0 415G 24 -14,-0.5 51,-0.3 -2,-0.3 2,-0.2 -0.405 99.0 -6.6 90.4-157.2 80.8 -31.2 49.7 365 382 A L - 0 0 39 49,-2.9 40,-0.1 40,-0.1 -2,-0.1 -0.450 56.5-130.4 -83.9 145.0 82.7 -31.8 52.9 366 383 A T > - 0 0 17 -2,-0.2 4,-2.0 -158,-0.1 5,-0.2 -0.393 40.3 -99.4 -78.1 168.1 84.9 -29.3 54.8 367 384 A E H > S+ 0 0 54 1,-0.2 4,-2.1 2,-0.2 5,-0.1 0.892 123.8 49.1 -59.1 -38.1 88.3 -30.5 55.7 368 385 A D H > S+ 0 0 106 2,-0.2 4,-2.4 1,-0.2 -1,-0.2 0.883 108.9 50.9 -71.3 -36.9 87.2 -31.3 59.2 369 386 A E H > S+ 0 0 94 1,-0.2 4,-1.5 2,-0.2 -1,-0.2 0.865 112.7 47.5 -68.1 -34.7 84.1 -33.2 58.2 370 387 A A H X>S+ 0 0 0 -4,-2.0 4,-2.9 2,-0.2 5,-0.6 0.874 109.7 53.2 -72.4 -38.6 86.2 -35.3 55.9 371 388 A I H X5S+ 0 0 37 -4,-2.1 4,-1.9 1,-0.2 -2,-0.2 0.931 111.7 45.7 -62.4 -42.4 88.8 -35.9 58.6 372 389 A H H <5S+ 0 0 175 -4,-2.4 -1,-0.2 1,-0.2 -2,-0.2 0.805 118.3 42.9 -69.5 -31.2 86.0 -37.1 60.9 373 390 A K H <5S+ 0 0 135 -4,-1.5 -2,-0.2 -5,-0.2 -1,-0.2 0.832 131.5 18.5 -84.6 -34.8 84.5 -39.3 58.2 374 391 A Y H <5S- 0 0 52 -4,-2.9 -3,-0.2 -5,-0.1 -2,-0.2 0.669 108.5-108.8-109.5 -24.7 87.6 -40.8 56.7 375 392 A G ><< - 0 0 20 -4,-1.9 3,-1.9 -5,-0.6 4,-0.2 0.226 30.3 -88.6 101.1 137.1 90.3 -40.3 59.3 376 393 A I G > S+ 0 0 116 1,-0.3 3,-1.2 2,-0.2 -1,-0.1 0.798 125.3 57.5 -43.4 -43.0 93.3 -38.0 59.2 377 394 A E G 3 S+ 0 0 160 1,-0.2 -1,-0.3 -6,-0.1 -2,-0.1 0.808 108.1 48.1 -64.7 -24.8 95.4 -40.5 57.5 378 395 A N G < S+ 0 0 65 -3,-1.9 30,-2.5 -7,-0.1 2,-0.5 0.200 94.8 84.6-101.5 11.5 93.0 -40.8 54.6 379 396 A V E < +S 407 0G 22 -3,-1.2 2,-0.4 28,-0.2 28,-0.2 -0.975 47.6 176.4-121.2 129.1 92.4 -37.1 53.8 380 397 A K E -S 406 0G 111 26,-2.2 26,-3.2 -2,-0.5 2,-0.3 -0.995 10.2-163.0-129.0 129.7 94.6 -35.0 51.6 381 398 A T E -S 405 0G 36 -2,-0.4 2,-0.4 24,-0.2 24,-0.2 -0.889 5.7-162.5-115.0 151.4 93.8 -31.4 50.7 382 399 A Y E +S 404 0G 24 22,-2.3 22,-3.3 -2,-0.3 2,-0.3 -0.991 19.5 169.2-127.0 136.2 95.2 -29.2 47.9 383 400 A S E -S 403 0G 71 -2,-0.4 2,-0.3 20,-0.2 20,-0.2 -0.912 15.5-171.3-144.5 166.8 94.9 -25.5 48.1 384 401 A T E -S 402 0G 38 18,-1.9 18,-2.4 -2,-0.3 2,-0.4 -0.967 6.3-162.6-153.8 154.4 96.1 -22.3 46.4 385 402 A S E +S 401 0G 69 -2,-0.3 2,-0.3 16,-0.2 16,-0.2 -0.982 25.9 150.2-143.8 124.9 95.8 -18.6 47.1 386 403 A F E -S 400 0G 45 14,-2.3 14,-2.6 -2,-0.4 -2,-0.0 -0.966 47.3-108.2-150.3 167.2 96.5 -16.1 44.4 387 404 A T - 0 0 77 -2,-0.3 12,-0.2 12,-0.2 -2,-0.0 -0.902 47.5-113.6-101.9 117.9 95.6 -12.6 43.2 388 405 A P > - 0 0 4 0, 0.0 3,-2.6 0, 0.0 4,-0.2 -0.181 21.2-114.8 -52.6 145.8 93.4 -12.8 40.1 389 406 A M G > S+ 0 0 140 1,-0.3 3,-1.9 2,-0.2 4,-0.3 0.752 112.0 73.8 -52.3 -28.5 94.9 -11.4 36.8 390 407 A Y G 3 S+ 0 0 65 1,-0.3 3,-0.5 2,-0.1 -1,-0.3 0.804 97.3 48.0 -56.2 -32.7 92.2 -8.8 36.9 391 408 A H G X S+ 0 0 0 -3,-2.6 3,-0.9 1,-0.2 -1,-0.3 0.322 78.7 101.1 -93.2 6.8 94.1 -7.0 39.7 392 409 A A T < S+ 0 0 75 -3,-1.9 -1,-0.2 1,-0.3 -2,-0.1 0.766 96.0 32.0 -60.9 -23.7 97.5 -7.2 38.0 393 410 A V T 3 S+ 0 0 85 -3,-0.5 2,-0.3 -4,-0.3 -1,-0.3 0.317 105.4 89.7-117.6 9.0 96.9 -3.6 37.2 394 411 A T < - 0 0 6 -3,-0.9 -330,-0.1 2,-0.2 -3,-0.0 -0.772 62.7-144.4-112.9 155.0 94.9 -2.2 40.1 395 412 A K S S+ 0 0 183 -2,-0.3 2,-0.3 2,-0.0 -1,-0.1 0.726 89.9 72.9 -78.8 -31.6 95.7 -0.7 43.5 396 413 A R S S- 0 0 59 -333,-0.1 2,-0.3 -3,-0.0 -2,-0.2 -0.644 71.8-169.3 -82.8 145.1 92.7 -2.5 45.0 397 414 A K - 0 0 109 -2,-0.3 2,-0.3 -5,-0.0 -2,-0.0 -0.973 18.5-178.8-140.3 150.1 93.2 -6.2 45.5 398 415 A T - 0 0 16 -2,-0.3 2,-0.3 -10,-0.1 -7,-0.1 -0.913 25.4-129.7-137.2 160.7 91.1 -9.2 46.4 399 416 A K - 0 0 78 -2,-0.3 2,-0.5 -12,-0.2 -12,-0.2 -0.711 3.2-142.8-111.8 162.9 92.3 -12.7 46.7 400 417 A C E -S 386 0G 0 -14,-2.6 -14,-2.3 -2,-0.3 2,-0.4 -0.996 20.4-174.6-126.2 120.0 91.1 -15.9 45.3 401 418 A V E -ST 385 419G 8 18,-2.3 18,-2.1 -2,-0.5 2,-0.4 -0.967 2.4-179.0-116.7 135.9 91.4 -19.0 47.6 402 419 A M E -ST 384 418G 0 -18,-2.4 -18,-1.9 -2,-0.4 2,-0.4 -0.996 4.4-176.8-134.2 142.1 90.7 -22.5 46.5 403 420 A K E -ST 383 417G 11 14,-2.5 14,-2.3 -2,-0.4 2,-0.5 -0.997 7.9-163.7-140.6 133.2 90.8 -25.8 48.5 404 421 A M E -ST 382 416G 0 -22,-3.3 -22,-2.3 -2,-0.4 2,-0.6 -0.967 9.6-154.4-117.0 125.8 90.1 -29.3 47.2 405 422 A V E -ST 381 415G 0 10,-3.2 9,-2.5 -2,-0.5 10,-1.3 -0.910 15.4-172.2-104.9 115.7 89.4 -32.0 49.8 406 423 A C E -ST 380 413G 1 -26,-3.2 -26,-2.2 -2,-0.6 2,-0.4 -0.807 5.8-155.9-108.4 148.3 90.3 -35.5 48.7 407 424 A A E > -ST 379 412G 0 5,-2.1 5,-2.3 -2,-0.3 4,-0.4 -0.949 47.0 -8.2-126.6 145.4 89.6 -38.8 50.4 408 425 A N T > 5S- 0 0 61 -30,-2.5 3,-1.4 -2,-0.4 -28,-0.1 0.182 96.4 -53.6 63.5 175.4 91.3 -42.3 50.2 409 426 A K T 3 5S+ 0 0 196 1,-0.3 -1,-0.2 2,-0.1 -30,-0.0 0.847 135.5 51.1 -51.0 -45.7 93.9 -43.7 47.9 410 427 A E T 3 5S- 0 0 88 -3,-0.1 30,-0.5 30,-0.0 31,-0.4 0.630 107.7-127.7 -72.4 -11.6 92.1 -42.7 44.7 411 428 A E T < 5 - 0 0 47 -3,-1.4 29,-2.0 -4,-0.4 2,-0.2 0.971 27.1-160.5 59.1 58.9 91.7 -39.2 46.0 412 429 A K E < -UT 439 407G 96 -5,-2.3 -5,-2.1 27,-0.2 2,-1.0 -0.498 23.9-117.5 -67.5 129.7 88.0 -38.9 45.5 413 430 A V E + T 0 406G 3 25,-2.5 -7,-0.2 -7,-0.2 24,-0.1 -0.664 45.9 164.3 -74.9 105.9 87.1 -35.2 45.4 414 431 A V E + 0 0 10 -9,-2.5 -49,-2.9 -2,-1.0 2,-0.3 0.492 60.8 21.5-100.3 -8.9 84.8 -34.9 48.5 415 432 A G E -RT 364 405G 0 -10,-1.3 -10,-3.2 -51,-0.3 2,-0.4 -0.951 50.4-172.6-163.1 139.6 84.9 -31.1 48.8 416 433 A I E +RT 363 404G 0 -53,-2.6 -53,-2.2 -2,-0.3 2,-0.4 -0.998 14.4 174.3-133.4 126.9 85.6 -27.9 46.9 417 434 A H E +RT 362 403G 0 -14,-2.3 -14,-2.5 -2,-0.4 2,-0.3 -1.000 9.9 154.0-135.5 132.7 85.7 -24.5 48.7 418 435 A M E -RT 361 402G 0 -57,-2.2 -57,-2.4 -2,-0.4 2,-0.3 -0.997 25.1-163.7-158.4 156.6 86.7 -21.3 47.1 419 436 A Q E +RT 360 401G 1 -18,-2.1 -18,-2.3 -2,-0.3 2,-0.2 -0.988 42.9 91.3-142.3 135.0 86.3 -17.5 47.3 420 437 A G S > S- 0 0 0 -61,-2.1 3,-1.9 -2,-0.3 4,-0.3 -0.855 75.5 -43.6 158.6 168.1 87.1 -15.1 44.5 421 438 A L T 3 S+ 0 0 38 1,-0.3 32,-0.1 -2,-0.2 -31,-0.1 -0.385 124.1 14.7 -59.3 129.0 86.0 -13.2 41.4 422 439 A G T >> S+ 0 0 37 -2,-0.1 4,-1.4 31,-0.1 3,-0.9 0.276 87.6 119.4 88.4 -9.6 83.9 -15.4 39.2 423 440 A C H <> + 0 0 0 -3,-1.9 4,-1.1 1,-0.2 -2,-0.1 0.706 65.1 66.2 -62.6 -21.7 83.4 -18.1 41.8 424 441 A D H 34 S+ 0 0 35 -4,-0.3 4,-0.3 1,-0.2 -1,-0.2 0.881 112.3 30.7 -66.2 -39.4 79.6 -17.7 41.7 425 442 A E H <4 S+ 0 0 147 -3,-0.9 4,-0.3 1,-0.1 -2,-0.2 0.597 113.2 66.8 -93.1 -14.3 79.3 -18.9 38.0 426 443 A M H X S+ 0 0 26 -4,-1.4 4,-0.8 1,-0.2 3,-0.3 0.773 87.6 65.5 -77.6 -30.8 82.3 -21.3 38.4 427 444 A L H X S+ 0 0 4 -4,-1.1 4,-2.3 1,-0.2 3,-0.3 0.857 79.9 73.5 -66.4 -39.8 80.8 -23.8 40.8 428 445 A Q H > S+ 0 0 131 -4,-0.3 4,-1.3 1,-0.2 -1,-0.2 0.843 99.8 44.9 -47.7 -48.2 77.9 -25.5 39.0 429 446 A G H > S+ 0 0 49 -3,-0.3 4,-1.9 -4,-0.3 -1,-0.2 0.890 112.8 48.8 -65.5 -43.1 80.1 -27.6 36.7 430 447 A F H X S+ 0 0 34 -4,-0.8 4,-2.7 -3,-0.3 -1,-0.2 0.834 107.3 58.2 -66.1 -27.7 82.5 -28.8 39.4 431 448 A A H X S+ 0 0 6 -4,-2.3 4,-2.1 2,-0.2 -1,-0.2 0.872 104.7 50.8 -68.0 -34.2 79.4 -29.6 41.5 432 449 A V H X S+ 0 0 79 -4,-1.3 4,-1.6 -5,-0.2 -2,-0.2 0.927 111.3 48.1 -67.0 -43.7 78.3 -31.9 38.6 433 450 A A H X>S+ 0 0 28 -4,-1.9 5,-2.0 1,-0.2 4,-0.7 0.897 112.0 48.4 -62.0 -44.1 81.8 -33.6 38.6 434 451 A V H ><5S+ 0 0 6 -4,-2.7 3,-1.0 1,-0.2 -1,-0.2 0.901 108.6 53.5 -64.9 -41.5 81.8 -34.0 42.4 435 452 A K H 3<5S+ 0 0 113 -4,-2.1 -1,-0.2 1,-0.2 -2,-0.2 0.861 106.7 54.0 -61.4 -34.0 78.3 -35.5 42.3 436 453 A M H 3<5S- 0 0 158 -4,-1.6 -1,-0.2 -5,-0.1 -2,-0.2 0.638 122.5-105.5 -74.8 -16.4 79.6 -38.0 39.7 437 454 A G T <<5 - 0 0 32 -3,-1.0 -3,-0.2 -4,-0.7 -2,-0.1 0.814 50.3-175.5 95.6 34.3 82.4 -39.2 42.0 438 455 A A < - 0 0 10 -5,-2.0 -25,-2.5 -25,-0.1 2,-0.2 -0.266 10.2-150.7 -63.4 151.1 85.3 -37.5 40.3 439 456 A T B >> -U 412 0G 31 -27,-0.3 4,-1.5 -33,-0.1 3,-0.7 -0.662 35.0 -96.5-112.0 172.9 88.8 -38.1 41.6 440 457 A K H 3> S+ 0 0 5 -29,-2.0 4,-3.0 -30,-0.5 5,-0.2 0.869 124.0 59.6 -61.4 -35.0 91.8 -35.7 41.5 441 458 A A H 3> S+ 0 0 50 -31,-0.4 4,-1.8 1,-0.2 -1,-0.2 0.842 100.3 55.0 -63.4 -33.2 93.0 -37.5 38.3 442 459 A D H <4 S+ 0 0 87 -3,-0.7 -1,-0.2 2,-0.2 -2,-0.2 0.943 112.3 43.0 -65.4 -46.2 89.7 -36.6 36.5 443 460 A F H >< S+ 0 0 8 -4,-1.5 3,-1.8 1,-0.2 -2,-0.2 0.957 113.7 52.0 -61.5 -49.3 90.3 -33.0 37.3 444 461 A D H 3< S+ 0 0 70 -4,-3.0 -1,-0.2 1,-0.3 -2,-0.2 0.756 106.7 53.7 -59.4 -27.8 94.0 -33.2 36.4 445 462 A N T 3< S+ 0 0 133 -4,-1.8 2,-0.5 -5,-0.2 -1,-0.3 0.285 85.9 96.6 -90.8 4.3 93.2 -34.8 33.0 446 463 A T S < S- 0 0 84 -3,-1.8 2,-0.1 12,-0.2 -4,-0.0 -0.881 83.2-118.0 -95.5 126.9 90.9 -32.1 31.9 447 464 A V - 0 0 133 -2,-0.5 -2,-0.1 1,-0.1 2,-0.1 -0.421 33.5-116.7 -65.3 135.7 92.6 -29.5 29.7 448 465 A A - 0 0 36 -4,-0.1 2,-0.6 -2,-0.1 -1,-0.1 -0.334 10.8-129.8 -73.4 158.2 92.6 -26.0 31.3 449 466 A I - 0 0 116 -2,-0.1 3,-0.4 3,-0.0 6,-0.4 -0.968 39.7-123.0-109.8 116.1 91.0 -22.9 29.9 450 467 A H S S+ 0 0 146 -2,-0.6 3,-0.1 1,-0.3 0, 0.0 -0.941 80.3 19.0-116.5 140.9 93.5 -20.1 29.9 451 468 A P S S+ 0 0 78 0, 0.0 2,-0.3 0, 0.0 -1,-0.3 0.356 96.0 105.1 -93.3 121.6 93.5 -17.3 31.1 452 469 A T S S- 0 0 54 -3,-0.4 4,-0.1 1,-0.1 -63,-0.1 -0.884 70.3-122.9-144.0 171.3 90.8 -17.8 33.8 453 470 A S S > S+ 0 0 28 -2,-0.3 3,-1.7 1,-0.1 4,-0.3 0.767 107.7 67.6 -85.0 -30.1 90.7 -18.3 37.5 454 471 A S G > S+ 0 0 31 1,-0.3 3,-1.3 2,-0.2 4,-0.4 0.755 84.5 70.0 -60.7 -29.6 88.8 -21.6 37.0 455 472 A E G > S+ 0 0 28 -6,-0.4 3,-0.9 1,-0.2 -1,-0.3 0.708 83.6 72.7 -63.1 -19.9 91.8 -23.3 35.5 456 473 A E G X S+ 0 0 56 -3,-1.7 3,-0.8 1,-0.2 -1,-0.2 0.804 89.8 59.8 -64.6 -29.5 93.5 -23.2 38.9 457 474 A L G < S+ 0 0 0 -3,-1.3 3,-0.3 -4,-0.3 -1,-0.2 0.691 106.0 45.5 -73.1 -21.2 91.2 -26.0 40.1 458 475 A V G < S+ 0 0 17 -3,-0.9 -1,-0.2 -4,-0.4 -2,-0.2 0.313 113.8 50.1-102.4 5.0 92.4 -28.4 37.4 459 476 A T S < S+ 0 0 76 -3,-0.8 2,-0.2 -4,-0.2 -1,-0.2 0.026 73.8 136.1-128.9 27.7 96.1 -27.6 37.9 460 477 A L 0 0 6 -3,-0.3 -76,-0.1 1,-0.1 -3,-0.0 -0.552 360.0 360.0 -75.9 142.3 96.5 -28.0 41.7 461 478 A R 0 0 276 -78,-0.2 -1,-0.1 -2,-0.2 0, 0.0 0.534 360.0 360.0-140.9 360.0 99.6 -29.9 42.9