==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=21-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HORMONE/GROWTH FACTOR 10-FEB-05 1YTO . COMPND 2 MOLECULE: HEPARIN-BINDING GROWTH FACTOR 1; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR J.LEE,M.BLABER . 559 4 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 25339.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 369 66.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 182 32.6 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 4 0.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 24 4.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 2 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 63 11.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 71 12.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 13 2.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 4 0.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 24 5 0 9 5 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 0 0 0 0 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 1DA H 0 0 198 0, 0.0 2,-0.3 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 28.3 26.3 61.5 -23.2 2 1EA H - 0 0 41 1,-0.1 104,-0.0 106,-0.0 103,-0.0 -0.966 360.0-101.3-137.7 154.6 26.0 64.7 -21.2 3 1FA H - 0 0 55 -2,-0.3 -1,-0.1 1,-0.1 0, 0.0 -0.007 26.9-135.3 -58.0 171.5 24.7 68.3 -21.4 4 1GA F + 0 0 119 2,-0.1 2,-0.6 86,-0.1 -1,-0.1 -0.158 50.1 139.6-127.4 38.0 27.1 71.0 -22.0 5 2 A N - 0 0 98 86,-0.2 86,-3.1 49,-0.0 -2,-0.0 -0.763 36.6-164.6 -81.7 120.6 26.1 73.7 -19.5 6 3 A L - 0 0 65 -2,-0.6 84,-0.1 84,-0.2 -2,-0.1 -0.818 16.2-135.4-113.1 150.3 29.3 75.1 -18.2 7 4 A P - 0 0 13 0, 0.0 84,-0.1 0, 0.0 47,-0.1 -0.325 48.5 -85.6 -86.4 178.8 30.2 77.3 -15.1 8 5 A P - 0 0 104 0, 0.0 -2,-0.0 0, 0.0 83,-0.0 0.880 52.7-160.5 -57.0 -35.1 32.6 80.3 -15.5 9 6 A G - 0 0 18 1,-0.2 2,-0.8 2,-0.0 45,-0.1 0.972 10.9-175.3 52.3 63.6 35.5 77.9 -15.0 10 7 A N + 0 0 130 1,-0.1 -1,-0.2 2,-0.0 38,-0.1 -0.819 10.2 169.9 -90.3 109.7 38.1 80.5 -14.0 11 8 A Y + 0 0 51 -2,-0.8 -1,-0.1 1,-0.1 37,-0.1 0.463 49.8 94.2-102.5 -1.0 41.3 78.4 -13.7 12 9 A K S S+ 0 0 201 35,-0.1 -1,-0.1 2,-0.0 -2,-0.0 0.946 87.4 42.6 -55.8 -52.9 43.9 81.2 -13.4 13 10 A K S S- 0 0 144 1,-0.1 35,-0.3 -3,-0.1 2,-0.0 -0.610 91.9-109.5 -97.5 153.7 43.9 81.2 -9.6 14 11 A P + 0 0 44 0, 0.0 125,-0.6 0, 0.0 2,-0.3 -0.385 45.9 177.1 -72.1 161.8 43.9 78.1 -7.3 15 12 A K E -AB 46 138A 14 31,-2.9 31,-3.2 123,-0.2 2,-0.3 -0.922 28.8-105.6-154.0-178.9 40.7 77.5 -5.4 16 13 A L E - B 0 137A 1 121,-3.2 121,-2.8 -2,-0.3 2,-0.6 -0.844 19.7-143.5-112.4 152.0 38.8 75.3 -3.1 17 14 A L E - B 0 136A 0 27,-0.4 8,-2.5 -2,-0.3 2,-0.7 -0.945 17.4-164.5-117.6 107.4 35.9 73.0 -4.0 18 15 A Y E -CB 24 135A 81 117,-2.3 117,-1.7 -2,-0.6 6,-0.3 -0.849 11.2-142.2 -99.0 116.0 33.3 73.0 -1.2 19 16 A C E > - B 0 134A 0 4,-3.4 3,-2.4 -2,-0.7 4,-0.3 -0.493 17.5-125.0 -76.3 142.8 30.8 70.2 -1.4 20 17 A S T 3 S+ 0 0 22 113,-2.5 111,-0.2 110,-0.7 -1,-0.1 0.663 108.8 70.2 -62.2 -14.4 27.2 70.9 -0.5 21 18 A N T 3 S- 0 0 17 109,-0.3 -1,-0.3 112,-0.3 96,-0.1 0.437 125.2 -95.6 -83.1 3.0 27.4 68.1 2.0 22 20 A G S < S+ 0 0 8 -3,-2.4 2,-0.3 1,-0.3 -2,-0.2 0.550 86.6 104.1 101.5 10.0 29.7 70.3 4.1 23 21 A H - 0 0 10 -4,-0.3 -4,-3.4 90,-0.1 2,-0.4 -0.938 61.1-129.9-129.5 150.2 33.3 69.4 3.2 24 22 A F E -CD 18 36A 11 12,-3.3 12,-1.7 -2,-0.3 -6,-0.2 -0.756 42.0-105.8 -90.3 137.1 36.1 70.8 1.1 25 23 A L E - D 0 35A 1 -8,-2.5 2,-0.4 -2,-0.4 -8,-0.3 -0.452 43.6-165.5 -65.0 131.9 37.6 68.2 -1.3 26 24 A R E - D 0 34A 45 8,-3.0 8,-2.2 -2,-0.2 2,-0.6 -0.976 19.4-162.7-128.4 134.1 41.0 67.1 0.0 27 25 A I E - D 0 33A 0 16,-2.0 6,-0.2 -2,-0.4 36,-0.2 -0.951 22.3-151.7-114.3 112.0 43.8 65.2 -1.6 28 26 A L > - 0 0 32 4,-3.6 3,-2.1 -2,-0.6 49,-0.1 -0.446 23.8-111.5 -84.8 156.4 46.2 63.8 1.0 29 27 A P T 3 S+ 0 0 77 0, 0.0 -1,-0.1 0, 0.0 -2,-0.0 0.838 115.0 58.9 -51.0 -42.1 50.0 63.1 0.6 30 28 A D T 3 S- 0 0 121 1,-0.1 3,-0.1 2,-0.0 47,-0.1 0.417 126.2 -99.7 -71.9 2.8 49.5 59.3 0.8 31 29 A G S < S+ 0 0 13 -3,-2.1 46,-2.3 1,-0.3 2,-0.2 0.537 79.5 141.1 90.7 7.3 47.3 59.6 -2.2 32 30 A T - 0 0 65 44,-0.2 -4,-3.6 -4,-0.0 2,-0.4 -0.583 36.6-154.9 -83.7 145.7 44.1 59.4 -0.2 33 31 A V E +D 27 0A 11 42,-0.5 86,-0.4 -6,-0.2 2,-0.3 -0.960 31.9 123.0-122.2 139.9 41.1 61.5 -1.1 34 32 A D E -D 26 0A 33 -8,-2.2 -8,-3.0 -2,-0.4 2,-0.3 -0.883 49.9 -86.6-167.3-163.7 38.4 62.7 1.3 35 33 A G E -D 25 0A 6 82,-2.6 2,-0.3 -2,-0.3 -10,-0.2 -0.943 28.6-173.3-128.4 151.9 36.6 65.7 2.7 36 34 A T E -D 24 0A 18 -12,-1.7 -12,-3.3 -2,-0.3 81,-0.1 -0.981 26.2-146.9-141.0 152.9 37.3 68.1 5.6 37 35 A R S S+ 0 0 164 -2,-0.3 2,-0.9 -14,-0.2 -1,-0.1 0.561 73.0 103.5 -91.5 -11.3 35.4 71.0 7.2 38 36 A D > - 0 0 74 1,-0.2 3,-1.8 -14,-0.1 6,-0.1 -0.633 52.8-167.3 -81.2 104.3 38.7 72.8 8.1 39 37 A R T 3 S+ 0 0 128 -2,-0.9 -1,-0.2 1,-0.3 5,-0.1 0.586 85.4 61.8 -63.9 -11.8 39.1 75.6 5.6 40 38 A S T 3 S+ 0 0 90 3,-0.0 -1,-0.3 2,-0.0 -2,-0.1 0.536 71.6 125.4 -92.5 -8.8 42.7 76.0 6.8 41 39 A D X - 0 0 20 -3,-1.8 3,-1.0 1,-0.2 4,-0.1 -0.271 58.3-143.3 -53.6 131.5 43.8 72.6 5.7 42 40 A Q T 3 S+ 0 0 106 1,-0.2 20,-0.2 2,-0.1 3,-0.2 0.463 93.8 63.0 -79.4 -0.2 46.8 72.9 3.4 43 41 A H T 3 S+ 0 0 27 1,-0.1 -16,-2.0 19,-0.1 -1,-0.2 0.243 86.5 69.5-108.9 14.2 45.6 70.0 1.2 44 42 A I < + 0 0 0 -3,-1.0 2,-0.7 -18,-0.2 -27,-0.4 0.378 68.8 106.3-108.0 0.3 42.3 71.5 -0.0 45 43 A Q - 0 0 39 -3,-0.2 16,-2.1 -4,-0.1 17,-0.5 -0.734 55.3-172.4 -82.4 117.9 44.0 74.2 -2.3 46 44 A L E -AE 15 60A 0 -31,-3.2 -31,-2.9 -2,-0.7 2,-0.6 -0.853 23.5-150.3-119.1 151.3 43.4 73.0 -5.8 47 45 A Q E - E 0 59A 59 12,-3.1 12,-2.0 -2,-0.3 2,-0.3 -0.957 16.7-159.0-120.7 111.7 44.7 74.0 -9.2 48 46 A L E - E 0 58A 4 -2,-0.6 2,-0.3 -35,-0.3 10,-0.2 -0.705 11.0-178.7 -91.1 142.3 42.3 73.3 -12.0 49 47 A S E - E 0 57A 50 8,-1.9 8,-2.6 -2,-0.3 2,-0.3 -0.991 20.7-125.1-139.1 145.0 43.6 73.2 -15.6 50 48 A A E + E 0 56A 51 -2,-0.3 6,-0.2 6,-0.2 3,-0.1 -0.679 21.7 177.7 -96.7 144.2 41.6 72.6 -18.8 51 49 A E S S- 0 0 102 4,-1.5 -1,-0.1 1,-0.7 3,-0.1 0.400 77.8 -6.7-102.2-113.2 42.2 70.0 -21.5 52 50 A S S > S- 0 0 73 1,-0.2 3,-2.3 2,-0.1 -1,-0.7 -0.284 109.7 -65.3 -72.8 169.2 39.5 70.3 -24.2 53 51 A V T 3 S+ 0 0 111 1,-0.3 -1,-0.2 -3,-0.1 3,-0.1 -0.327 127.2 15.3 -57.5 132.3 36.7 72.9 -23.4 54 52 A G T 3 S+ 0 0 6 1,-0.3 35,-2.5 -3,-0.1 2,-0.4 0.379 105.2 104.8 85.3 -6.3 34.7 71.7 -20.4 55 53 A E E < - F 0 88A 18 -3,-2.3 -4,-1.5 33,-0.2 2,-0.3 -0.875 48.5-178.4-106.9 142.4 37.3 69.1 -19.3 56 54 A V E -EF 50 87A 0 31,-3.0 31,-2.4 -2,-0.4 2,-0.4 -0.949 27.6-143.1-141.4 159.6 39.6 69.7 -16.3 57 55 A Y E -E 49 0A 34 -8,-2.6 -8,-1.9 -2,-0.3 2,-0.5 -0.892 21.1-151.0-111.8 145.4 42.5 68.2 -14.3 58 56 A I E -E 48 0A 1 27,-0.4 9,-3.1 -2,-0.4 2,-0.4 -0.978 20.9-176.7-122.6 112.0 42.2 68.9 -10.6 59 57 A K E -EG 47 66A 67 -12,-2.0 -12,-3.1 -2,-0.5 2,-0.5 -0.912 30.5-118.7-120.4 143.3 45.6 69.1 -8.9 60 58 A S E > -E 46 0A 0 5,-3.3 4,-2.0 -2,-0.4 -14,-0.2 -0.621 16.6-157.0 -72.3 120.9 46.8 69.5 -5.3 61 59 A T T 4 S+ 0 0 68 -16,-2.1 -1,-0.2 -2,-0.5 -15,-0.1 0.843 93.4 48.1 -68.5 -29.3 48.9 72.7 -5.2 62 60 A E T 4 S+ 0 0 102 -17,-0.5 -1,-0.2 -20,-0.2 -19,-0.1 0.931 128.2 17.6 -76.1 -50.4 50.6 71.3 -2.1 63 61 A T T 4 S- 0 0 42 -36,-0.2 -2,-0.2 2,-0.1 -1,-0.1 0.548 91.6-129.1-101.5 -11.1 51.5 67.8 -3.2 64 62 A G < + 0 0 27 -4,-2.0 2,-0.2 1,-0.3 -3,-0.1 0.571 59.0 144.6 73.0 5.6 51.2 68.1 -7.0 65 63 A Q - 0 0 10 -38,-0.1 -5,-3.3 -6,-0.1 2,-0.3 -0.551 45.5-131.3 -80.0 147.8 49.0 65.1 -7.1 66 64 A Y E -GH 59 78A 37 12,-3.5 12,-3.0 -7,-0.2 -7,-0.2 -0.750 19.6-117.2 -96.5 140.1 46.1 64.8 -9.6 67 65 A L E + H 0 77A 0 -9,-3.1 -9,-0.3 -2,-0.3 2,-0.3 -0.508 46.9 165.9 -72.5 144.8 42.6 63.8 -8.5 68 66 A A E - H 0 76A 0 8,-1.5 8,-2.0 -2,-0.1 2,-0.4 -0.974 32.2-138.8-155.7 165.9 41.5 60.6 -10.3 69 67 A M E - H 0 75A 0 15,-1.6 6,-0.2 -2,-0.3 17,-0.1 -0.988 23.1-141.2-135.3 125.3 39.0 57.8 -10.2 70 68 A D > - 0 0 35 4,-2.5 3,-2.9 -2,-0.4 52,-0.1 -0.137 36.7 -87.4 -80.9 175.6 39.9 54.1 -10.8 71 69 A T T 3 S+ 0 0 70 1,-0.3 -1,-0.1 2,-0.1 -2,-0.0 0.718 129.2 52.7 -53.7 -24.7 38.1 51.3 -12.6 72 70 A D T 3 S- 0 0 12 2,-0.1 -1,-0.3 50,-0.0 -2,-0.0 0.337 121.6-105.5 -95.5 6.1 36.2 50.6 -9.4 73 71 A G S < S+ 0 0 0 -3,-2.9 49,-2.5 1,-0.3 2,-0.4 0.675 72.6 141.0 81.9 18.1 35.0 54.2 -9.0 74 72 A L - 0 0 37 47,-0.2 -4,-2.5 48,-0.1 2,-0.3 -0.798 48.3-130.1 -99.7 135.6 37.3 55.1 -6.2 75 73 A L E +H 69 0A 16 -2,-0.4 -42,-0.5 45,-0.3 2,-0.3 -0.611 38.4 156.4 -81.7 138.8 39.0 58.5 -5.9 76 74 A Y E -H 68 0A 61 -8,-2.0 -8,-1.5 -2,-0.3 2,-0.5 -0.933 43.4 -96.9-152.5 171.2 42.7 58.6 -5.3 77 75 A G E -H 67 0A 13 -46,-2.3 2,-0.4 -2,-0.3 -10,-0.2 -0.861 35.4-162.9-101.4 128.8 45.7 60.9 -5.9 78 76 A S E -H 66 0A 11 -12,-3.0 -12,-3.5 -2,-0.5 -47,-0.1 -0.889 20.8-151.2-113.5 140.4 47.9 60.3 -8.9 79 77 A Q S S+ 0 0 135 -2,-0.4 -1,-0.1 -14,-0.2 -48,-0.0 0.816 88.1 48.7 -74.1 -31.2 51.4 61.6 -9.6 80 78 A T S S- 0 0 91 -14,-0.1 2,-1.8 -15,-0.0 -14,-0.1 -0.874 87.6-119.7-113.4 145.5 50.8 61.6 -13.3 81 79 A P + 0 0 56 0, 0.0 -14,-0.0 0, 0.0 -13,-0.0 -0.394 51.2 162.4 -80.6 62.8 47.8 63.0 -15.3 82 80 A N > - 0 0 56 -2,-1.8 3,-2.2 1,-0.1 4,-0.3 0.013 59.3 -80.3 -71.8-177.4 46.5 59.8 -16.9 83 81 A E G > S+ 0 0 126 1,-0.3 3,-0.6 2,-0.2 20,-0.5 0.683 127.7 63.1 -59.6 -21.1 43.1 59.2 -18.5 84 82 A E G 3 S+ 0 0 34 1,-0.2 -15,-1.6 18,-0.1 -1,-0.3 0.531 94.5 61.7 -83.0 -6.7 41.6 58.6 -15.1 85 83 A C G < S+ 0 0 0 -3,-2.2 2,-0.4 -17,-0.2 -27,-0.4 0.512 79.4 101.8 -94.9 -9.1 42.4 62.2 -14.0 86 84 A L < - 0 0 16 -3,-0.6 16,-2.4 -4,-0.3 17,-0.6 -0.679 49.9-176.1 -83.4 129.0 40.2 63.9 -16.6 87 85 A F E -FI 56 101A 0 -31,-2.4 -31,-3.0 -2,-0.4 2,-0.8 -0.936 27.4-129.6-125.4 145.2 36.9 65.2 -15.5 88 86 A L E -FI 55 100A 18 12,-3.0 12,-2.0 -2,-0.3 2,-0.6 -0.837 26.2-151.5 -92.4 113.7 34.0 66.9 -17.3 89 87 A E E + I 0 99A 5 -35,-2.5 2,-0.3 -2,-0.8 10,-0.2 -0.782 24.9 171.1 -92.2 120.6 33.2 70.0 -15.3 90 88 A R E - I 0 98A 16 8,-2.4 8,-2.5 -2,-0.6 -84,-0.2 -0.948 35.3-112.3-132.3 150.0 29.5 71.0 -15.7 91 89 A L E - I 0 97A 33 -86,-3.1 2,-0.3 -2,-0.3 6,-0.2 -0.451 32.6-166.3 -72.8 150.6 27.1 73.4 -14.2 92 90 A E E >> - 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