==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=6-JAN-2010 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER PROTEIN BINDING 05-APR-07 2YT0 . COMPND 2 MOLECULE: AMYLOID BETA A4 PROTEIN AND AMYLOID BETA A4 . SOURCE 2 ORGANISM_SCIENTIFIC: MUS MUSCULUS; . AUTHOR H.LI,S.KOSHIBA,N.TOCHIO,S.WATANABE,T.HARADA,T.KIGAWA, . 176 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 11764.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 116 65.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 45 25.6 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 1.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 19 10.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 16 9.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 33 18.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 1 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 0 0 0 0 1 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 1 0 2 2 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 1 A G 0 0 119 0, 0.0 2,-0.4 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 177.0 -19.9 -2.1 -32.4 2 2 A S + 0 0 143 1,-0.0 2,-0.3 2,-0.0 0, 0.0 -0.291 360.0 147.4 -52.2 105.7 -17.5 0.4 -34.1 3 3 A S + 0 0 123 -2,-0.4 2,-0.3 0, 0.0 3,-0.1 -0.921 25.1 63.3-150.3 119.7 -19.0 3.7 -32.8 4 4 A G + 0 0 56 -2,-0.3 -2,-0.0 1,-0.1 0, 0.0 -0.864 14.9 138.5 171.7-135.0 -17.2 6.9 -32.0 5 5 A S + 0 0 136 -2,-0.3 -1,-0.1 1,-0.0 0, 0.0 0.840 47.9 126.4 63.2 33.8 -15.1 9.6 -33.8 6 6 A S - 0 0 111 -3,-0.1 -1,-0.0 2,-0.1 -2,-0.0 0.872 61.7-136.2 -87.7 -43.7 -16.9 12.3 -31.8 7 7 A G + 0 0 69 1,-0.2 2,-0.3 0, 0.0 -3,-0.0 0.874 41.3 145.8 83.8 94.1 -13.9 14.0 -30.3 8 8 A D - 0 0 142 2,-0.0 2,-0.6 0, 0.0 -1,-0.2 -0.925 34.7-157.5-162.2 133.8 -14.2 15.0 -26.6 9 9 A A + 0 0 97 -2,-0.3 2,-0.7 2,-0.0 0, 0.0 -0.750 29.5 153.4-116.6 83.5 -11.8 15.2 -23.7 10 10 A A + 0 0 93 -2,-0.6 2,-0.3 2,-0.0 -1,-0.0 -0.729 24.6 129.5-112.9 81.5 -13.8 14.9 -20.5 11 11 A V - 0 0 92 -2,-0.7 -2,-0.0 3,-0.0 0, 0.0 -0.973 53.0-116.7-134.7 148.8 -11.4 13.5 -17.9 12 12 A T > - 0 0 68 -2,-0.3 4,-1.3 1,-0.1 3,-0.4 -0.479 19.7-126.8 -82.8 153.3 -10.5 14.5 -14.3 13 13 A P H > S+ 0 0 109 0, 0.0 4,-0.5 0, 0.0 -1,-0.1 0.721 110.3 57.7 -69.7 -22.0 -7.0 15.6 -13.3 14 14 A E H > S+ 0 0 68 1,-0.2 4,-1.4 2,-0.2 3,-0.2 0.761 105.6 49.1 -79.4 -26.6 -7.0 13.0 -10.5 15 15 A E H > S+ 0 0 52 -3,-0.4 4,-2.5 2,-0.2 5,-0.2 0.780 92.6 76.2 -82.0 -29.3 -7.6 10.2 -13.0 16 16 A R H X S+ 0 0 182 -4,-1.3 4,-0.7 1,-0.2 -1,-0.2 0.853 109.1 30.8 -49.2 -38.3 -4.8 11.3 -15.3 17 17 A H H >X S+ 0 0 39 -4,-0.5 4,-1.5 -3,-0.2 3,-0.6 0.932 113.7 57.4 -86.0 -56.1 -2.4 9.8 -12.8 18 18 A L H 3X S+ 0 0 0 -4,-1.4 4,-2.0 1,-0.2 118,-0.2 0.776 100.5 66.4 -46.1 -28.0 -4.4 6.9 -11.4 19 19 A S H >X S+ 0 0 50 -4,-2.5 4,-2.0 1,-0.2 3,-0.5 0.979 99.4 44.9 -59.3 -60.4 -4.7 5.8 -15.0 20 20 A K H S+ 0 0 81 -4,-0.7 4,-2.2 -3,-0.6 5,-1.2 0.813 111.6 57.2 -54.4 -31.0 -1.0 5.0 -15.4 21 21 A M H 3<5S+ 0 0 0 -4,-1.5 -1,-0.3 1,-0.2 115,-0.2 0.902 108.2 44.1 -67.8 -42.1 -1.2 3.3 -12.0 22 22 A Q H <<5S+ 0 0 58 -4,-2.0 -2,-0.2 -3,-0.5 -1,-0.2 0.778 114.4 52.9 -73.1 -27.3 -3.9 0.9 -13.1 23 23 A Q H <5S- 0 0 139 -4,-2.0 -2,-0.2 -5,-0.2 -3,-0.2 0.992 138.6 -13.3 -70.9 -65.4 -2.1 0.3 -16.4 24 24 A N T <5S- 0 0 70 -4,-2.2 56,-0.4 1,-0.2 2,-0.3 0.836 88.0-155.4-103.4 -60.1 1.3 -0.7 -15.1 25 25 A G < - 0 0 3 -5,-1.2 2,-0.3 54,-0.1 110,-0.2 -0.895 30.0 -57.0 120.1-149.7 1.5 0.2 -11.5 26 26 A Y E -A 134 0A 57 108,-0.7 108,-1.9 -2,-0.3 2,-0.6 -0.883 41.6-172.0-144.0 108.2 4.4 0.9 -9.2 27 27 A E E -A 133 0A 100 -2,-0.3 106,-0.2 106,-0.2 105,-0.1 -0.886 27.7-123.2-104.6 122.4 7.3 -1.5 -8.6 28 28 A N - 0 0 9 104,-2.3 4,-0.5 -2,-0.6 5,-0.1 -0.443 15.5-158.9 -65.2 123.2 9.8 -0.6 -5.8 29 29 A P S >> S+ 0 0 64 0, 0.0 4,-2.8 0, 0.0 3,-1.4 0.888 89.2 59.9 -69.7 -41.1 13.3 -0.5 -7.3 30 30 A T H 3> S+ 0 0 73 1,-0.3 4,-0.8 2,-0.2 99,-0.1 0.865 94.1 65.6 -56.0 -38.0 15.1 -1.0 -4.0 31 31 A Y H 34 S+ 0 0 51 100,-0.3 -1,-0.3 1,-0.2 101,-0.1 0.815 116.0 28.9 -54.7 -31.3 13.3 -4.3 -3.6 32 32 A K H <4 S+ 0 0 133 -3,-1.4 -2,-0.2 -4,-0.5 -1,-0.2 0.708 117.9 56.7-100.1 -28.0 15.3 -5.5 -6.6 33 33 A F H >< S+ 0 0 141 -4,-2.8 3,-0.9 1,-0.2 2,-0.8 0.338 76.0 103.6 -85.4 7.1 18.3 -3.3 -6.1 34 34 A F T 3< + 0 0 119 -4,-0.8 -1,-0.2 -5,-0.2 3,-0.1 -0.099 49.9 99.8 -81.2 38.6 18.7 -4.8 -2.6 35 35 A E T 3 + 0 0 144 -2,-0.8 2,-1.1 1,-0.2 -1,-0.2 0.834 63.9 70.5 -90.8 -39.5 21.6 -6.9 -3.9 36 36 A Q S < S+ 0 0 180 -3,-0.9 2,-0.3 2,-0.1 -1,-0.2 -0.691 73.8 119.1 -84.7 98.2 24.5 -4.8 -2.6 37 37 A M - 0 0 107 -2,-1.1 2,-0.5 -3,-0.1 -3,-0.0 -0.960 60.1-124.0-152.8 167.3 24.4 -5.3 1.2 38 38 A Q + 0 0 194 -2,-0.3 2,-0.2 2,-0.0 -2,-0.1 -0.806 33.8 179.3-122.2 89.6 26.5 -6.6 4.1 39 39 A N - 0 0 142 -2,-0.5 2,-0.3 2,-0.0 -2,-0.0 -0.495 13.1-146.6 -87.4 158.5 24.6 -9.3 6.0 40 40 A S - 0 0 116 -2,-0.2 2,-0.3 2,-0.1 -2,-0.0 -0.923 9.2-161.2-126.6 151.4 26.0 -11.1 9.1 41 41 A G + 0 0 82 -2,-0.3 2,-0.3 2,-0.0 3,-0.0 -0.681 32.5 142.7-134.8 82.5 25.6 -14.7 10.4 42 42 A S - 0 0 114 -2,-0.3 -2,-0.1 1,-0.1 0, 0.0 -0.796 61.9 -67.3-118.6 161.3 26.5 -15.1 14.0 43 43 A S S S+ 0 0 133 -2,-0.3 -1,-0.1 1,-0.1 -2,-0.0 -0.182 74.9 127.4 -47.1 124.2 25.0 -17.1 16.9 44 44 A G - 0 0 57 -3,-0.0 2,-0.3 2,-0.0 -1,-0.1 0.049 37.5-165.2-178.2 51.2 21.6 -15.8 17.6 45 45 A S + 0 0 131 2,-0.1 2,-0.3 0, 0.0 -2,-0.0 -0.280 41.8 124.9 -51.4 106.3 18.8 -18.4 17.6 46 46 A S - 0 0 102 -2,-0.3 2,-0.2 2,-0.0 -2,-0.0 -0.986 64.7-124.5-162.3 159.3 15.7 -16.3 17.5 47 47 A G S S+ 0 0 83 -2,-0.3 2,-0.3 2,-0.0 -2,-0.1 -0.353 84.4 62.4-106.9 52.3 12.5 -15.7 15.5 48 48 A S S S- 0 0 89 -2,-0.2 2,-1.7 3,-0.0 3,-0.1 -0.960 85.8-108.5-168.8 151.8 12.9 -12.0 14.8 49 49 A S S S- 0 0 130 -2,-0.3 2,-0.2 1,-0.1 -2,-0.0 -0.253 75.3 -89.6 -81.3 50.4 15.2 -9.5 13.0 50 50 A G - 0 0 58 -2,-1.7 2,-0.3 2,-0.0 -1,-0.1 -0.560 69.8 -43.1 82.2-143.9 16.5 -8.2 16.3 51 51 A S - 0 0 116 -2,-0.2 -3,-0.0 1,-0.1 0, 0.0 -0.928 33.3-170.5-128.5 152.4 14.7 -5.3 18.0 52 52 A S - 0 0 111 -2,-0.3 -1,-0.1 1,-0.1 -2,-0.0 0.801 26.1-172.8-105.3 -48.8 13.3 -2.0 16.8 53 53 A G - 0 0 51 2,-0.0 -1,-0.1 0, 0.0 2,-0.0 -0.506 44.5 -3.2 88.1-157.3 12.5 -0.1 20.0 54 54 A P S S- 0 0 127 0, 0.0 0, 0.0 0, 0.0 0, 0.0 -0.260 82.3 -93.6 -69.7 157.9 10.7 3.2 20.3 55 55 A T - 0 0 108 1,-0.1 -2,-0.0 -2,-0.0 -3,-0.0 -0.480 41.9-117.5 -75.2 141.6 9.5 5.2 17.2 56 56 A P - 0 0 96 0, 0.0 2,-0.1 0, 0.0 -1,-0.1 -0.074 32.8 -93.9 -69.7 174.3 11.8 7.9 15.8 57 57 A K + 0 0 190 51,-0.0 2,-0.3 2,-0.0 0, 0.0 -0.442 41.4 177.1 -88.8 165.0 11.0 11.6 15.6 58 58 A T - 0 0 75 -2,-0.1 3,-0.1 1,-0.1 49,-0.0 -0.956 27.2-165.3-166.8 147.7 9.5 13.5 12.7 59 59 A E S S+ 0 0 202 -2,-0.3 2,-0.3 1,-0.1 -1,-0.1 0.795 78.9 54.0-103.5 -44.0 8.3 16.9 11.6 60 60 A L + 0 0 138 2,-0.0 48,-0.5 46,-0.0 2,-0.3 -0.704 62.4 150.9 -96.2 146.7 6.3 16.2 8.5 61 61 A V - 0 0 54 -2,-0.3 2,-0.4 46,-0.2 46,-0.2 -0.894 28.6-147.3-172.9 141.4 3.5 13.7 8.2 62 62 A Q - 0 0 89 -2,-0.3 44,-2.0 109,-0.0 2,-0.5 -0.959 9.3-160.6-120.3 133.1 0.3 13.1 6.3 63 63 A K E -B 105 0A 103 -2,-0.4 2,-0.4 42,-0.2 42,-0.2 -0.950 7.7-173.7-116.0 124.5 -2.8 11.4 7.6 64 64 A F E -B 104 0A 42 40,-2.0 40,-2.7 -2,-0.5 2,-0.9 -0.964 24.0-130.1-120.4 130.5 -5.5 10.0 5.3 65 65 A R E +B 103 0A 191 -2,-0.4 97,-0.5 38,-0.2 2,-0.3 -0.670 47.4 149.7 -80.8 106.2 -8.8 8.5 6.4 66 66 A V E -BC 102 161A 6 36,-2.4 36,-2.9 -2,-0.9 2,-0.2 -0.839 40.1-115.3-132.2 169.6 -9.2 5.1 4.8 67 67 A Q E -BC 101 160A 46 93,-2.2 93,-1.2 -2,-0.3 2,-0.5 -0.689 23.1-123.0-105.8 159.8 -10.8 1.8 5.5 68 68 A Y E + C 0 159A 38 32,-1.9 91,-0.2 -2,-0.2 89,-0.0 -0.883 24.9 174.2-106.7 131.1 -9.2 -1.6 6.1 69 69 A L E - 0 0 10 89,-2.0 2,-0.2 -2,-0.5 -1,-0.1 0.796 47.5-110.8 -99.6 -40.0 -10.1 -4.6 3.9 70 70 A G E - C 0 158A 17 88,-0.9 88,-1.7 2,-0.0 2,-0.3 -0.645 34.8 -57.4 130.4 172.1 -7.7 -7.2 5.3 71 71 A M E - C 0 157A 80 -2,-0.2 86,-0.2 86,-0.2 84,-0.0 -0.633 43.1-169.3 -89.9 147.0 -4.6 -9.2 4.3 72 72 A L E - C 0 156A 31 84,-1.8 84,-2.4 -2,-0.3 2,-0.1 -0.974 19.7-127.1-141.6 124.2 -4.4 -11.5 1.3 73 73 A P E - C 0 155A 85 0, 0.0 2,-0.2 0, 0.0 82,-0.2 -0.438 30.3-170.2 -69.8 137.2 -1.7 -14.0 0.4 74 74 A V - 0 0 33 80,-1.1 80,-0.3 -2,-0.1 9,-0.0 -0.651 29.5-136.4-120.7 178.0 -0.2 -13.7 -3.1 75 75 A D S S+ 0 0 133 1,-0.2 -1,-0.1 -2,-0.2 3,-0.0 0.624 88.5 36.9-107.9 -22.5 2.0 -15.7 -5.4 76 76 A R - 0 0 157 3,-0.1 -1,-0.2 1,-0.1 78,-0.0 -0.978 67.8-136.4-134.9 146.8 4.2 -12.9 -6.7 77 77 A P S S+ 0 0 24 0, 0.0 2,-0.3 0, 0.0 56,-0.2 0.759 93.2 26.5 -69.8 -25.6 5.6 -9.7 -5.1 78 78 A V S S+ 0 0 59 54,-0.1 -3,-0.1 -51,-0.1 55,-0.1 -0.854 70.7 101.8-133.6 168.8 4.6 -7.7 -8.3 79 79 A G >> - 0 0 22 -2,-0.3 4,-1.8 -55,-0.2 3,-1.2 0.432 54.1-131.0 118.2 103.5 2.1 -7.9 -11.1 80 80 A M H 3> S+ 0 0 24 -56,-0.4 4,-2.6 1,-0.3 5,-0.4 0.910 109.7 57.7 -41.7 -57.5 -1.1 -5.8 -11.4 81 81 A D H 3> S+ 0 0 125 1,-0.3 4,-0.9 2,-0.2 -1,-0.3 0.857 106.5 51.0 -42.8 -42.7 -3.1 -9.0 -12.2 82 82 A T H X> S+ 0 0 21 -3,-1.2 4,-1.1 2,-0.2 3,-0.7 0.941 110.4 47.1 -62.9 -49.3 -1.9 -10.3 -8.8 83 83 A L H >X S+ 0 0 0 -4,-1.8 4,-1.7 -3,-0.3 3,-1.1 0.957 105.8 57.1 -57.5 -54.5 -2.9 -7.2 -6.9 84 84 A N H 3X S+ 0 0 32 -4,-2.6 4,-1.9 1,-0.3 -1,-0.3 0.770 101.6 61.6 -48.6 -26.8 -6.4 -7.0 -8.5 85 85 A S H - 0 0 67 -2,-0.3 4,-1.1 1,-0.1 -3,-0.1 -0.230 34.1-100.3 -81.1 174.2 -18.7 -5.5 2.3 96 96 A K T 4 S+ 0 0 112 1,-0.2 3,-0.1 2,-0.2 -1,-0.1 0.875 126.7 37.7 -62.6 -38.4 -17.9 -1.9 1.7 97 97 A E T 4 S+ 0 0 168 1,-0.2 -1,-0.2 -30,-0.0 -3,-0.0 0.828 103.7 69.7 -81.8 -34.7 -19.4 -0.9 5.1 98 98 A D T 4 S+ 0 0 103 2,-0.0 -1,-0.2 -29,-0.0 -2,-0.2 0.800 79.8 96.4 -52.7 -29.7 -18.0 -4.0 6.8 99 99 A W S < S- 0 0 10 -4,-1.1 -30,-0.1 -3,-0.1 -29,-0.0 -0.493 77.0-133.4 -68.4 121.4 -14.6 -2.5 6.4 100 100 A P - 0 0 78 0, 0.0 -32,-1.9 0, 0.0 2,-0.3 -0.157 22.1 -99.8 -69.7 167.5 -13.6 -0.6 9.6 101 101 A S E +B 67 0A 47 -34,-0.2 15,-1.1 -36,-0.0 16,-0.3 -0.699 44.0 168.8 -93.5 143.2 -12.1 2.9 9.6 102 102 A V E -BD 66 115A 4 -36,-2.9 -36,-2.4 -2,-0.3 2,-0.5 -0.994 30.9-125.1-153.4 146.9 -8.4 3.5 10.0 103 103 A N E -BD 65 114A 30 11,-2.4 11,-3.0 -2,-0.3 2,-0.5 -0.830 21.9-148.0 -98.2 126.3 -5.9 6.4 9.7 104 104 A M E -BD 64 113A 1 -40,-2.7 -40,-2.0 -2,-0.5 2,-0.5 -0.805 8.7-154.5 -96.2 128.6 -2.9 6.0 7.4 105 105 A N E -BD 63 112A 27 7,-1.3 7,-1.4 -2,-0.5 -42,-0.2 -0.874 14.0-175.7-105.6 132.1 0.3 7.8 8.3 106 106 A V > + 0 0 13 -44,-2.0 3,-0.5 -2,-0.5 2,-0.3 -0.314 33.7 141.1-119.0 48.1 2.9 8.7 5.6 107 107 A A G > + 0 0 17 3,-0.5 3,-2.4 1,-0.2 -46,-0.2 -0.663 69.7 3.2 -92.6 146.9 5.6 10.1 7.8 108 108 A D G 3 S- 0 0 97 -48,-0.5 -1,-0.2 1,-0.3 3,-0.1 0.901 126.4 -67.1 46.3 49.0 9.3 9.5 7.2 109 109 A A G < S+ 0 0 36 -3,-0.5 19,-1.0 1,-0.2 2,-0.4 0.792 110.1 129.0 43.7 31.5 8.4 7.7 4.0 110 110 A T E < - E 0 127A 20 -3,-2.4 2,-0.6 17,-0.2 -3,-0.5 -0.925 55.1-139.9-119.5 142.7 6.9 5.1 6.3 111 111 A V E + E 0 126A 9 15,-2.2 15,-3.3 -2,-0.4 2,-0.4 -0.887 23.8 171.1-104.8 121.3 3.4 3.5 6.3 112 112 A T E -DE 105 125A 23 -7,-1.4 2,-1.3 -2,-0.6 -7,-1.3 -0.896 26.4-144.7-133.5 104.4 1.7 3.0 9.6 113 113 A V E -DE 104 124A 1 11,-2.4 10,-2.6 -2,-0.4 11,-1.1 -0.518 26.1-164.5 -69.5 95.5 -2.0 1.9 9.6 114 114 A I E -DE 103 122A 9 -11,-3.0 -11,-2.4 -2,-1.3 2,-0.3 -0.561 21.9-108.8 -84.0 146.9 -3.2 3.8 12.7 115 115 A S E -D 102 0A 7 6,-2.0 6,-0.2 3,-0.6 -13,-0.2 -0.546 14.0-144.7 -76.7 136.1 -6.5 2.8 14.3 116 116 A E S S+ 0 0 98 -15,-1.1 3,-0.2 -2,-0.3 -14,-0.2 0.874 102.3 50.4 -66.5 -38.1 -9.4 5.4 13.9 117 117 A K S S+ 0 0 142 -16,-0.3 2,-0.4 1,-0.2 -1,-0.2 0.861 125.0 25.3 -68.2 -36.3 -10.7 4.6 17.4 118 118 A N > - 0 0 73 3,-0.2 3,-0.7 1,-0.1 -3,-0.6 -0.983 60.0-161.9-135.6 123.8 -7.2 5.1 18.9 119 119 A E T 3 S+ 0 0 111 -2,-0.4 2,-1.0 1,-0.3 -4,-0.2 0.904 94.6 58.0 -67.3 -42.6 -4.4 7.2 17.5 120 120 A E T 3 S+ 0 0 188 1,-0.1 2,-0.3 -6,-0.1 -1,-0.3 -0.144 86.7 97.4 -81.8 41.7 -1.8 5.5 19.6 121 121 A E < - 0 0 68 -2,-1.0 -6,-2.0 -3,-0.7 2,-1.1 -0.745 59.0-162.5-134.3 86.4 -2.8 2.1 18.1 122 122 A V E -E 114 0A 73 -2,-0.3 -8,-0.2 -8,-0.2 3,-0.2 -0.560 8.5-178.4 -72.2 99.8 -0.6 1.1 15.2 123 123 A L E S+ 0 0 68 -10,-2.6 2,-0.3 -2,-1.1 -1,-0.2 0.922 72.0 5.3 -64.7 -45.4 -2.6 -1.6 13.4 124 124 A V E -E 113 0A 27 -11,-1.1 -11,-2.4 -3,-0.1 2,-0.6 -0.994 62.5-157.3-145.4 135.9 0.1 -2.3 10.8 125 125 A E E +E 112 0A 92 -2,-0.3 2,-0.3 -13,-0.2 -13,-0.2 -0.932 23.1 164.5-117.9 110.5 3.7 -1.0 10.4 126 126 A C E -E 111 0A 2 -15,-3.3 -15,-2.2 -2,-0.6 2,-0.4 -0.940 21.4-149.5-126.1 147.6 5.2 -1.2 6.9 127 127 A R E >> -E 110 0A 65 -2,-0.3 4,-2.1 -17,-0.2 3,-1.1 -0.921 26.1-123.7-118.5 142.2 8.2 0.5 5.4 128 128 A V T 34 S+ 0 0 10 -19,-1.0 -18,-0.1 -2,-0.4 -98,-0.1 0.748 111.9 65.5 -51.1 -23.9 8.8 1.5 1.8 129 129 A R T 34 S+ 0 0 163 1,-0.2 -1,-0.3 47,-0.1 -19,-0.0 0.931 106.1 38.0 -65.7 -47.1 11.9 -0.7 2.0 130 130 A F T <4 S+ 0 0 102 -3,-1.1 -2,-0.2 17,-0.0 -1,-0.2 0.822 92.9 108.0 -73.5 -32.2 9.9 -3.9 2.5 131 131 A L < + 0 0 3 -4,-2.1 -100,-0.3 16,-0.2 16,-0.2 -0.225 41.0 173.8 -50.0 125.6 7.2 -2.7 -0.0 132 132 A S + 0 0 1 14,-3.1 -104,-2.3 1,-0.4 2,-0.3 0.854 60.6 2.5-100.7 -57.5 7.6 -4.7 -3.2 133 133 A F E +AF 27 146A 1 13,-0.8 13,-2.4 -56,-0.2 -1,-0.4 -0.952 58.6 174.4-134.6 153.6 4.6 -3.6 -5.4 134 134 A M E +AF 26 145A 0 -108,-1.9 -108,-0.7 -2,-0.3 2,-0.3 -0.910 17.1 128.1-161.5 130.0 1.8 -1.1 -5.1 135 135 A G E - F 0 144A 0 9,-1.3 9,-1.5 -2,-0.3 2,-0.4 -0.938 50.4 -81.5-164.2-175.6 -0.9 0.0 -7.5 136 136 A V E - F 0 143A 0 -2,-0.3 7,-0.2 -115,-0.2 -52,-0.1 -0.872 35.7-144.5-107.6 136.3 -4.6 0.6 -8.1 137 137 A G - 0 0 2 5,-1.8 -1,-0.1 -2,-0.4 5,-0.1 0.259 52.2 -61.0 -75.9-154.6 -7.1 -2.1 -9.1 138 138 A K S S+ 0 0 178 -54,-0.1 2,-0.2 3,-0.1 -116,-0.1 0.889 123.5 58.7 -60.0 -40.6 -10.1 -1.8 -11.4 139 139 A D S > S- 0 0 77 1,-0.1 3,-0.9 -117,-0.0 -2,-0.3 -0.610 79.9-135.7 -91.9 152.2 -11.7 0.8 -9.1 140 140 A V T 3 S+ 0 0 19 1,-0.2 25,-2.7 -2,-0.2 -1,-0.1 0.581 105.4 60.2 -80.3 -10.4 -10.0 4.1 -8.1 141 141 A H T 3 S+ 0 0 48 23,-0.2 20,-0.5 24,-0.1 2,-0.5 0.119 88.3 87.7-102.2 19.1 -11.1 3.5 -4.5 142 142 A T E < + G 0 160A 2 -3,-0.9 -5,-1.8 18,-0.2 2,-0.4 -0.922 49.5 165.6-124.5 106.7 -9.1 0.3 -4.3 143 143 A F E +FG 136 159A 2 16,-2.1 16,-2.5 -2,-0.5 2,-0.3 -0.979 5.1 172.7-124.7 128.4 -5.4 0.5 -3.2 144 144 A A E -FG 135 158A 0 -9,-1.5 -9,-1.3 -2,-0.4 2,-0.4 -0.956 12.6-162.4-133.6 152.1 -3.2 -2.4 -2.1 145 145 A F E -FG 134 157A 5 12,-1.7 12,-1.7 -2,-0.3 2,-0.4 -0.993 11.0-144.5-138.7 130.0 0.5 -2.8 -1.3 146 146 A I E -FG 133 156A 0 -13,-2.4 -14,-3.1 -2,-0.4 -13,-0.8 -0.785 21.5-176.1 -96.0 133.0 2.5 -6.0 -1.1 147 147 A M E - G 0 155A 22 8,-1.4 8,-1.1 -2,-0.4 2,-0.6 -0.722 26.3-115.5-120.9 171.7 5.3 -6.3 1.5 148 148 A D E + G 0 154A 49 -2,-0.2 6,-0.2 6,-0.2 3,-0.1 -0.926 25.6 174.0-114.7 111.3 7.9 -8.9 2.4 149 149 A T E - 0 0 71 4,-1.5 5,-0.1 -2,-0.6 -1,-0.1 0.480 56.9-101.3 -90.6 -4.4 7.6 -10.5 5.9 150 150 A G E > S+ G 0 153A 22 3,-0.8 3,-0.6 1,-0.0 -1,-0.3 -0.226 96.5 74.1 104.9 163.8 10.5 -12.9 5.1 151 151 A N T 3 S- 0 0 142 1,-0.2 3,-0.1 -2,-0.1 -2,-0.0 0.865 127.2 -62.9 61.7 37.1 10.8 -16.5 4.1 152 152 A Q T 3 S+ 0 0 162 1,-0.2 2,-0.4 -4,-0.0 -1,-0.2 0.853 101.4 145.5 56.4 36.3 9.6 -15.6 0.6 153 153 A R E < - G 0 150A 170 -3,-0.6 -4,-1.5 2,-0.0 -3,-0.8 -0.894 29.7-171.0-109.9 134.7 6.3 -14.5 2.1 154 154 A F E - G 0 148A 37 -2,-0.4 -80,-1.1 -80,-0.3 2,-0.6 -0.987 7.0-159.9-128.4 128.9 4.3 -11.6 0.7 155 155 A E E -CG 73 147A 59 -8,-1.1 -8,-1.4 -2,-0.4 2,-0.8 -0.926 6.8-154.6-111.5 117.9 1.2 -10.1 2.4 156 156 A C E -CG 72 146A 0 -84,-2.4 -84,-1.8 -2,-0.6 2,-0.5 -0.805 12.6-168.7 -94.3 109.8 -1.2 -8.1 0.2 157 157 A H E -CG 71 145A 9 -12,-1.7 -12,-1.7 -2,-0.8 2,-0.3 -0.860 4.6-156.0-102.3 127.8 -3.1 -5.5 2.2 158 158 A V E -CG 70 144A 0 -88,-1.7 -89,-2.0 -2,-0.5 -88,-0.9 -0.784 11.1-177.3-103.4 145.7 -6.0 -3.7 0.6 159 159 A F E -CG 68 143A 0 -16,-2.5 -16,-2.1 -2,-0.3 2,-0.6 -0.996 22.0-133.4-144.6 136.3 -7.4 -0.3 1.7 160 160 A W E -CG 67 142A 12 -93,-1.2 -93,-2.2 -2,-0.3 2,-0.3 -0.791 26.1-170.1 -92.9 122.0 -10.3 1.8 0.6 161 161 A C E -C 66 0A 0 -2,-0.6 4,-0.2 -20,-0.5 -95,-0.1 -0.817 16.8-105.5-111.9 151.7 -9.6 5.5 -0.0 162 162 A E S S- 0 0 95 -97,-0.5 -97,-0.1 -2,-0.3 -21,-0.0 -0.985 89.8 -3.9-141.9 151.4 -11.9 8.4 -0.7 163 163 A P S S- 0 0 93 0, 0.0 2,-0.3 0, 0.0 -1,-0.2 -0.990 137.9 -39.4 -69.7 0.2 -13.0 10.2 -2.6 164 164 A N - 0 0 21 -23,-0.1 4,-0.4 -4,-0.1 3,-0.4 -0.972 51.5 -99.7-168.6 175.0 -10.3 8.1 -4.4 165 165 A A S > S+ 0 0 0 -25,-2.7 4,-0.6 -2,-0.3 5,-0.3 -0.029 90.6 100.2 -97.8 29.7 -6.9 6.5 -4.1 166 166 A A H > S+ 0 0 0 3,-0.2 4,-1.6 2,-0.1 -1,-0.2 0.905 85.7 37.9 -79.6 -45.1 -5.2 9.4 -5.9 167 167 A N H > S+ 0 0 62 -3,-0.4 4,-3.2 2,-0.2 5,-0.3 0.995 117.5 46.5 -69.2 -67.0 -3.8 11.2 -2.9 168 168 A V H > S+ 0 0 4 -4,-0.4 4,-1.7 1,-0.2 5,-0.2 0.916 117.6 42.6 -38.9 -68.7 -2.8 8.2 -0.7 169 169 A S H >X S+ 0 0 0 -4,-0.6 4,-1.4 1,-0.2 3,-1.1 0.929 113.5 52.7 -45.7 -57.6 -1.0 6.4 -3.5 170 170 A E H >X S+ 0 0 104 -4,-1.6 3,-1.2 1,-0.3 4,-1.0 0.911 108.1 50.7 -45.5 -52.4 0.6 9.6 -4.8 171 171 A A H 3X S+ 0 0 18 -4,-3.2 4,-0.7 1,-0.3 -1,-0.3 0.813 109.0 52.9 -57.5 -30.7 1.9 10.3 -1.3 172 172 A V H