data_6549
#######################
# Entry information #
#######################
save_entry_information
_Saveframe_category entry_information
_Entry_title
;
Sequential Backbone Assignment and Secondary Structure of Peroxisome
Proliferator-Activated Receptor g Ligand Binding Domain
;
_BMRB_accession_number 6549
_BMRB_flat_file_name bmr6549.str
_Entry_type original
_Submission_date 2005-03-17
_Accession_date 2005-03-17
_Entry_origination author
_NMR_STAR_version 2.1.1
_Experimental_method NMR
_Details .
loop_
_Author_ordinal
_Author_family_name
_Author_given_name
_Author_middle_initials
_Author_family_title
1 Riepl Hubert . .
2 Hartl Rainer . .
3 Bauer Margit . .
4 Nar Herbert . .
5 Kauschke Stefan . .
6 Kalbitzer 'Hans Robert' . .
7 Maurer Till . .
stop_
loop_
_Saveframe_category_type
_Saveframe_category_type_count
assigned_chemical_shifts 1
stop_
loop_
_Data_type
_Data_type_count
"1H chemical shifts" 225
"13C chemical shifts" 692
"15N chemical shifts" 225
stop_
loop_
_Revision_date
_Revision_keyword
_Revision_author
_Revision_detail
2006-02-17 original author .
stop_
_Original_release_date 2006-02-17
save_
#############################
# Citation for this entry #
#############################
save_entry_citation
_Saveframe_category entry_citation
_Citation_full .
_Citation_title
;
Sequential Backbone Assignment of Peroxisome Proliferator-Activated Receptor-g
Ligand Binding Domain
;
_Citation_status published
_Citation_type journal
_CAS_abstract_code .
_MEDLINE_UI_code .
_PubMed_ID 16132831
loop_
_Author_ordinal
_Author_family_name
_Author_given_name
_Author_middle_initials
_Author_family_title
1 Riepl Hubert . .
2 Hartl Rainer . .
3 Bauer Margit . .
4 Nar Herbert . .
5 Kauschke Stefan . .
6 Kalbitzer 'Hans Robert' . .
7 Maurer Till . .
stop_
_Journal_abbreviation 'J. Biomol. NMR'
_Journal_volume 32
_Journal_issue 3
_Journal_CSD .
_Book_chapter_title .
_Book_volume .
_Book_series .
_Book_ISBN .
_Conference_state_province .
_Conference_abstract_number .
_Page_first 259
_Page_last 259
_Year 2005
_Details .
save_
##################################
# Molecular system description #
##################################
save_LBD_Pparg
_Saveframe_category molecular_system
_Mol_system_name 'ligand binding domain of peroxisome proliferator-activated receptor gamma'
_Abbreviation_common 'LBD Pparg'
_Enzyme_commission_number .
loop_
_Mol_system_component_name
_Mol_label
'LBD Pparg' $Pparg
stop_
_System_molecular_weight .
_System_physical_state native
_System_oligomer_state monomer
_System_paramagnetic no
_System_thiol_state 'not reported'
_Database_query_date .
_Details .
save_
########################
# Monomeric polymers #
########################
save_Pparg
_Saveframe_category monomeric_polymer
_Mol_type polymer
_Mol_polymer_class protein
_Name_common 'peroxisome proliferator-activated receptor gamma'
_Abbreviation_common Pparg
_Molecular_mass .
_Mol_thiol_state 'not reported'
_Details .
##############################
# Polymer residue sequence #
##############################
_Residue_count 270
_Mol_residue_sequence
;
ESADLRALAKHLYDSYIKSF
PLTKAKARAILTGKTTDKSP
FVIYDMNSLMMGEDKIKFKH
ITPLQEQSKEVAIRIFQGCQ
FRSVEAVQEITEYAKSIPGF
VNLDLNDQVTLLKYGVHEII
YTMLASLMNKDGVLISEGQG
FMTREFLKSLRKPFGDFMEP
KFEFAVKFNALELDDSDLAI
FIAVIILSGDRPGLLNVKPI
EDIQDNLLQALELQLKLNHP
ESSQLFAKLLQKMTDLRQIV
TEHVQLLQVIKKTETDMSLH
PLLQEIYKDL
;
loop_
_Residue_seq_code
_Residue_label
1 GLU 2 SER 3 ALA 4 ASP 5 LEU
6 ARG 7 ALA 8 LEU 9 ALA 10 LYS
11 HIS 12 LEU 13 TYR 14 ASP 15 SER
16 TYR 17 ILE 18 LYS 19 SER 20 PHE
21 PRO 22 LEU 23 THR 24 LYS 25 ALA
26 LYS 27 ALA 28 ARG 29 ALA 30 ILE
31 LEU 32 THR 33 GLY 34 LYS 35 THR
36 THR 37 ASP 38 LYS 39 SER 40 PRO
41 PHE 42 VAL 43 ILE 44 TYR 45 ASP
46 MET 47 ASN 48 SER 49 LEU 50 MET
51 MET 52 GLY 53 GLU 54 ASP 55 LYS
56 ILE 57 LYS 58 PHE 59 LYS 60 HIS
61 ILE 62 THR 63 PRO 64 LEU 65 GLN
66 GLU 67 GLN 68 SER 69 LYS 70 GLU
71 VAL 72 ALA 73 ILE 74 ARG 75 ILE
76 PHE 77 GLN 78 GLY 79 CYS 80 GLN
81 PHE 82 ARG 83 SER 84 VAL 85 GLU
86 ALA 87 VAL 88 GLN 89 GLU 90 ILE
91 THR 92 GLU 93 TYR 94 ALA 95 LYS
96 SER 97 ILE 98 PRO 99 GLY 100 PHE
101 VAL 102 ASN 103 LEU 104 ASP 105 LEU
106 ASN 107 ASP 108 GLN 109 VAL 110 THR
111 LEU 112 LEU 113 LYS 114 TYR 115 GLY
116 VAL 117 HIS 118 GLU 119 ILE 120 ILE
121 TYR 122 THR 123 MET 124 LEU 125 ALA
126 SER 127 LEU 128 MET 129 ASN 130 LYS
131 ASP 132 GLY 133 VAL 134 LEU 135 ILE
136 SER 137 GLU 138 GLY 139 GLN 140 GLY
141 PHE 142 MET 143 THR 144 ARG 145 GLU
146 PHE 147 LEU 148 LYS 149 SER 150 LEU
151 ARG 152 LYS 153 PRO 154 PHE 155 GLY
156 ASP 157 PHE 158 MET 159 GLU 160 PRO
161 LYS 162 PHE 163 GLU 164 PHE 165 ALA
166 VAL 167 LYS 168 PHE 169 ASN 170 ALA
171 LEU 172 GLU 173 LEU 174 ASP 175 ASP
176 SER 177 ASP 178 LEU 179 ALA 180 ILE
181 PHE 182 ILE 183 ALA 184 VAL 185 ILE
186 ILE 187 LEU 188 SER 189 GLY 190 ASP
191 ARG 192 PRO 193 GLY 194 LEU 195 LEU
196 ASN 197 VAL 198 LYS 199 PRO 200 ILE
201 GLU 202 ASP 203 ILE 204 GLN 205 ASP
206 ASN 207 LEU 208 LEU 209 GLN 210 ALA
211 LEU 212 GLU 213 LEU 214 GLN 215 LEU
216 LYS 217 LEU 218 ASN 219 HIS 220 PRO
221 GLU 222 SER 223 SER 224 GLN 225 LEU
226 PHE 227 ALA 228 LYS 229 LEU 230 LEU
231 GLN 232 LYS 233 MET 234 THR 235 ASP
236 LEU 237 ARG 238 GLN 239 ILE 240 VAL
241 THR 242 GLU 243 HIS 244 VAL 245 GLN
246 LEU 247 LEU 248 GLN 249 VAL 250 ILE
251 LYS 252 LYS 253 THR 254 GLU 255 THR
256 ASP 257 MET 258 SER 259 LEU 260 HIS
261 PRO 262 LEU 263 LEU 264 GLN 265 GLU
266 ILE 267 TYR 268 LYS 269 ASP 270 LEU
stop_
_Sequence_homology_query_date .
_Sequence_homology_query_revised_last_date 2015-01-28
loop_
_Database_name
_Database_accession_code
_Database_entry_mol_name
_Sequence_query_to_submitted_percentage
_Sequence_subject_length
_Sequence_identity
_Sequence_positive
_Sequence_homology_expectation_value
BMRB 15518 Peroxisome_Proliferator-Activated_Receptor_Gamma_Ligand-Binding_Domain 100.00 279 100.00 100.00 0.00e+00
BMRB 17975 PPARgamma_LBD 100.00 276 100.00 100.00 0.00e+00
BMRB 17976 PPARgamma_LBD 100.00 276 100.00 100.00 0.00e+00
BMRB 17977 PPARgamma_LBD 100.00 276 100.00 100.00 0.00e+00
PDB 1FM6 "The 2.1 Angstrom Resolution Crystal Structure Of The Heterodimer Of The Human Rxralpha And Ppargamma Ligand Binding Domains Res" 100.00 272 100.00 100.00 0.00e+00
PDB 1FM9 "The 2.1 Angstrom Resolution Crystal Structure Of The Heterodimer Of The Human Rxralpha And Ppargamma Ligand Binding Domains Res" 100.00 272 100.00 100.00 0.00e+00
PDB 1I7I "Crystal Structure Of The Ligand Binding Domain Of Human Ppar-Gamma In Complex With The Agonist Az 242" 100.00 292 100.00 100.00 0.00e+00
PDB 1K74 "The 2.3 Angstrom Resolution Crystal Structure Of The Heterodimer Of The Human Ppargamma And Rxralpha Ligand Binding Domains Res" 100.00 283 100.00 100.00 0.00e+00
PDB 1KNU "Ligand Binding Domain Of The Human Peroxisome Proliferator Activated Receptor Gamma In Complex With A Synthetic Agonist" 100.00 274 100.00 100.00 0.00e+00
PDB 1NYX "Ligand Binding Domain Of The Human Peroxisome Proliferator Activated Receptor Gamma In Complex With An Agonist" 100.00 276 100.00 100.00 0.00e+00
PDB 1PRG "Ligand Binding Domain Of The Human Peroxisome Proliferator Activated Receptor Gamma" 100.00 270 100.00 100.00 0.00e+00
PDB 1RDT "Crystal Structure Of A New Rexinoid Bound To The Rxralpha Ligand Binding Doamin In The RxralphaPPARGAMMA HETERODIMER" 100.00 284 100.00 100.00 0.00e+00
PDB 1WM0 "Ppargamma In Complex With A 2-Baba Compound" 100.00 292 100.00 100.00 0.00e+00
PDB 1ZEO "Crystal Structure Of Human Ppar-Gamma Ligand Binding Domain Complexed With An Alpha-Aryloxyphenylacetic Acid Agonist" 100.00 277 100.00 100.00 0.00e+00
PDB 1ZGY "Structural And Biochemical Basis For Selective Repression Of The Orphan Nuclear Receptor Lrh-1 By Shp" 100.00 272 100.00 100.00 0.00e+00
PDB 2ATH "Crystal Structure Of The Ligand Binding Domain Of Human Ppar-Gamma Im Complex With An Agonist" 100.00 271 100.00 100.00 0.00e+00
PDB 2F4B "Crystal Structure Of The Ligand Binding Domain Of Human Ppar-Gamma In Complex With An Agonist" 100.00 271 100.00 100.00 0.00e+00
PDB 2FVJ "A Novel Anti-adipogenic Partial Agonist Of Peroxisome Proliferator- Activated Receptor-gamma (pparg) Recruits Pparg-coactivator" 100.00 271 100.00 100.00 0.00e+00
PDB 2G0G "Structure-based Drug Design Of A Novel Family Of Ppar Partial Agonists: Virtual Screening, X-ray Crystallography And In Vitro/i" 100.00 271 100.00 100.00 0.00e+00
PDB 2G0H "Structure-Based Drug Design Of A Novel Family Of Ppar Partial Agonists: Virtual Screening, X-Ray Crystallography And In VitroIN" 100.00 271 100.00 100.00 0.00e+00
PDB 2GTK "Structure-Based Design Of Indole Propionic Acids As Novel Pparag Co-Agonists" 100.00 271 100.00 100.00 0.00e+00
PDB 2HFP "Crystal Structure Of Ppar Gamma With N-Sulfonyl-2-Indole Carboxamide Ligands" 100.00 282 100.00 100.00 0.00e+00
PDB 2HWQ "Structural Basis For The Structure-Activity Relationships Of Peroxisome Proliferator-Activated Receptor Agonists" 100.00 271 100.00 100.00 0.00e+00
PDB 2HWR "Structural Basis For The Structure-Activity Relationships Of Peroxisome Proliferator-Activated Receptor Agonists" 100.00 271 100.00 100.00 0.00e+00
PDB 2I4J "Crystal Structure Of The Complex Between Ppargamma And The Agonist Lt160 (Ureidofibrate Derivative)" 100.00 286 100.00 100.00 0.00e+00
PDB 2I4P "Crystal Structure Of The Complex Between Ppargamma And The Partial Agonist Lt127 (Ureidofibrate Derivative). Structure Obtained" 100.00 286 100.00 100.00 0.00e+00
PDB 2I4Z "Crystal Structure Of The Complex Between Ppargamma And The Partial Agonist Lt127 (Ureidofibrate Derivative). This Structure Has" 100.00 286 100.00 100.00 0.00e+00
PDB 2OM9 "Ajulemic Acid, A Synthetic Cannabinoid Bound To Ppar Gamma" 100.00 278 100.00 100.00 0.00e+00
PDB 2P4Y "Crystal Structure Of Human Ppar-Gamma-Ligand Binding Domain Complexed With An Indole-Based Modulator" 100.00 277 100.00 100.00 0.00e+00
PDB 2POB "Ppargamma Ligand Binding Domain Complexed With A Farglitazar Analogue Gw4709" 100.00 272 100.00 100.00 0.00e+00
PDB 2PRG "Ligand-Binding Domain Of The Human Peroxisome Proliferator Activated Receptor Gamma" 100.00 271 100.00 100.00 0.00e+00
PDB 2Q59 "Crystal Structure Of Ppargamma Lbd Bound To Full Agonist Mrl20" 100.00 274 100.00 100.00 0.00e+00
PDB 2Q5P "Crystal Structure Of Ppargamma Bound To Partial Agonist Mrl24" 100.00 274 100.00 100.00 0.00e+00
PDB 2Q5S "Crystal Structure Of Ppargamma Bound To Partial Agonist Ntzdpa" 100.00 274 100.00 100.00 0.00e+00
PDB 2Q61 "Crystal Structure Of Ppargamma Ligand Binding Domain Bound To Partial Agonist Sr145" 100.00 274 100.00 100.00 0.00e+00
PDB 2Q6R "Crystal Structure Of Ppar Gamma Complexed With Partial Agonist Sf147" 100.00 274 100.00 100.00 0.00e+00
PDB 2Q6S "2.4 Angstrom Crystal Structure Of Ppar Gamma Complexed To Bvt.13 Without Co-Activator Peptides" 100.00 274 100.00 100.00 0.00e+00
PDB 2Q8S "X-Ray Crystal Structure Of The Nuclear Hormone Receptor Ppar-Gamma In A Complex With A Ppar GammaALPHA DUAL AGONIST" 100.00 271 100.00 100.00 0.00e+00
PDB 2QMV "High Resolution Structure Of Peroxisone Proliferation-Activated Receptor Gamma And Characterisation Of Its Interaction With The" 100.00 270 100.00 100.00 0.00e+00
PDB 2VSR "Hppargamma Ligand Binding Domain In Complex With 9-(S)-Hode" 100.00 276 100.00 100.00 0.00e+00
PDB 2VST "Hppargamma Ligand Binding Domain In Complex With 13-(S)- Hode" 100.00 276 100.00 100.00 0.00e+00
PDB 2VV0 "Hppargamma Ligand Binding Domain In Complex With Dha" 100.00 276 100.00 100.00 0.00e+00
PDB 2VV1 "Hppargamma Ligand Binding Domain In Complex With 4-Hdha" 100.00 276 100.00 100.00 0.00e+00
PDB 2VV2 "Hppargamma Ligand Binding Domain In Complex With 5-Hepa" 100.00 276 100.00 100.00 0.00e+00
PDB 2VV3 "Hppargamma Ligand Binding Domain In Complex With 4-Oxodha" 100.00 276 100.00 100.00 0.00e+00
PDB 2VV4 "Hppargamma Ligand Binding Domain In Complex With 6-Oxoote" 100.00 276 100.00 100.00 0.00e+00
PDB 2XKW "Ligand Binding Domain Of Human Ppar-Gamma In Complex With The Agonist Pioglitazone" 100.00 274 100.00 100.00 0.00e+00
PDB 2YFE "Ligand Binding Domain Of Human Ppar Gamma In Complex With Amorfrutin 1" 100.00 287 100.00 100.00 0.00e+00
PDB 2ZK0 "Human Peroxisome Proliferator-Activated Receptor Gamma Ligand Binding Domain" 100.00 286 100.00 100.00 0.00e+00
PDB 2ZK1 "Human Peroxisome Proliferator-Activated Receptor Gamma Ligand Binding Domain Complexed With 15-Deoxy-Delta12,14- Prostaglandin " 100.00 286 100.00 100.00 0.00e+00
PDB 2ZK2 "Human Peroxisome Proliferator-Activated Receptor Gamma Ligand Binding Domain Complexed With Glutathion Conjugated 15-Deoxy-Delt" 100.00 286 100.00 100.00 0.00e+00
PDB 2ZK3 "Human Peroxisome Proliferator-Activated Receptor Gamma Ligand Binding Domain Complexed With 8-Oxo- Eicosatetraenoic Acid" 100.00 286 100.00 100.00 0.00e+00
PDB 2ZK4 "Human Peroxisome Proliferator-Activated Receptor Gamma Ligand Binding Domain Complexed With 15-Oxo- Eicosatetraenoic Acid" 100.00 286 100.00 100.00 0.00e+00
PDB 2ZK5 "Human Peroxisome Proliferator-Activated Receptor Gamma Ligand Binding Domain Complexed With Nitro-233" 100.00 286 100.00 100.00 0.00e+00
PDB 2ZK6 "Human Peroxisome Proliferator-Activated Receptor Gamma Ligand Binding Domain Complexed With C8-Bodipy" 100.00 286 100.00 100.00 0.00e+00
PDB 2ZNO "Human Pprr Gamma Ligand Binding Domain In Complex With A Synthetic Agonist Tipp703" 100.00 286 100.00 100.00 0.00e+00
PDB 2ZVT "Cys285ser Mutant Ppargamma Ligand-Binding Domain Complexed With 15-Deoxy-Delta12,14-Prostaglandin J2" 100.00 286 99.63 99.63 0.00e+00
PDB 3ADS "Human Ppargamma Ligand-Binding Domain In Complex With Indomethacin" 100.00 287 100.00 100.00 0.00e+00
PDB 3ADT "Human Ppargamma Ligand-Binding Domain In Complex With 5-Hydroxy-Indole Acetate" 100.00 287 100.00 100.00 0.00e+00
PDB 3ADU "Human Ppargamma Ligand-Binding Domain In Complex With 5-Methoxy-Indole Acetate" 100.00 287 100.00 100.00 0.00e+00
PDB 3ADV "Human Ppargamma Ligand-Binding Domain In Complex With Serotonin" 100.00 287 100.00 100.00 0.00e+00
PDB 3ADW "Human Ppargamma Ligand-Binding Domain In Complex With 5-Methoxy-Indole Acetate And 15-Oxo-Eicosatetraenoic Acid" 100.00 287 100.00 100.00 0.00e+00
PDB 3ADX "Human Ppargamma Ligand-Binding Domain In Complex With Indomethacin And Nitro-233" 100.00 287 100.00 100.00 0.00e+00
PDB 3AN3 "Human Ppar Gamma Ligand Binding Domain In Complex With A Gamma Selective Agonist Mo3s" 100.00 286 100.00 100.00 0.00e+00
PDB 3AN4 "Human Ppar Gamma Ligand Binding Domain In Complex With A Gamma Selective Agonist Mo4r" 100.00 286 100.00 100.00 0.00e+00
PDB 3B0Q "Human Ppar Gamma Ligand Binding Domain In Complex With Mcc555" 100.00 274 100.00 100.00 0.00e+00
PDB 3B0R "Human Ppar Gamma Ligand Binding Dmain Complexed With Gw9662 In A Covalent Bonded Form" 100.00 274 100.00 100.00 0.00e+00
PDB 3B1M "Crystal Structure Of The Ppargamma-Lbd Complexed With A Cercosporamide Derivative Modulator Cerco-A" 100.00 283 100.00 100.00 0.00e+00
PDB 3B3K "Crystal Structure Of The Complex Between Ppargamma And The Full Agonist Lt175" 100.00 286 100.00 100.00 0.00e+00
PDB 3BC5 "X-Ray Crystal Structure Of Human Ppar Gamma With 2-(5-(3-(2- (5-Methyl-2-Phenyloxazol-4-Yl)ethoxy)benzyl)-2-Phenyl-2h-1, 2,3-Tr" 100.00 296 100.00 100.00 0.00e+00
PDB 3CDP "Crystal Structure Of Ppar-gamma Lbd Complexed With A Partial Agonist, Analogue Of Clofibric Acid" 100.00 286 100.00 100.00 0.00e+00
PDB 3CDS "Crystal Structure Of The Complex Between Ppar-Gamma And The Agonist Lt248 (Clofibric Acid Analogue)" 100.00 286 100.00 100.00 0.00e+00
PDB 3CS8 "Structural And Biochemical Basis For The Binding Selectivity Of Pparg To Pgc-1a" 100.00 275 100.00 100.00 0.00e+00
PDB 3CWD "Molecular Recognition Of Nitro-Fatty Acids By Ppar Gamma" 99.63 270 100.00 100.00 0.00e+00
PDB 3D6D "Crystal Structure Of The Complex Between Ppargamma Lbd And The Lt175(R-Enantiomer)" 100.00 286 100.00 100.00 0.00e+00
PDB 3DZU "Intact Ppar Gamma - Rxr Alpha Nuclear Receptor Complex On Dna Bound With Bvt.13, 9-Cis Retinoic Acid And Ncoa2 Peptide" 100.00 419 100.00 100.00 0.00e+00
PDB 3DZY "Intact Ppar Gamma - Rxr Alpha Nuclear Receptor Complex On Dna Bound With Rosiglitazone, 9-Cis Retinoic Acid And Ncoa2 Peptide" 100.00 419 100.00 100.00 0.00e+00
PDB 3E00 "Intact Ppar Gamma - Rxr Alpha Nuclear Receptor Complex On Dna Bound With Gw9662, 9-Cis Retinoic Acid And Ncoa2 Peptide" 100.00 419 100.00 100.00 0.00e+00
PDB 3ET0 "Structure Of Ppargamma With 3-(5-Methoxy-1h-Indol-3-Yl)- Propionic Acid" 100.00 292 99.63 99.63 0.00e+00
PDB 3ET3 "Structure Of Ppargamma With 3-[5-Methoxy-1-(4-Methoxy- Benzenesulfonyl)-1h-Indol-3-Yl]-Propionic Acid" 100.00 292 100.00 100.00 0.00e+00
PDB 3FEJ "Design And Biological Evaluation Of Novel, Balanced Dual PparaG AGONISTS" 100.00 271 100.00 100.00 0.00e+00
PDB 3FUR "Crystal Structure Of Pparg In Complex With Int131" 100.00 272 100.00 100.00 0.00e+00
PDB 3G9E "Aleglitaar. A New. Potent, And Balanced Dual PparaG AGONIST For The Treatment Of Type Ii Diabetes" 100.00 271 100.00 100.00 0.00e+00
PDB 3GBK "Crystal Structure Of Human Ppar-Gamma Ligand Binding Domain Complexed With A Potent And Selective Agonist" 100.00 271 100.00 100.00 0.00e+00
PDB 3H0A "Crystal Structure Of Peroxisome Proliferator-activated Receptor Gamma (pparg) And Retinoic Acid Receptor Alpha (rxra) In Comple" 100.00 272 100.00 100.00 0.00e+00
PDB 3HO0 "Crystal Structure Of The Ppargamma-Lbd Complexed With A New Aryloxy-3phenylpropanoic Acid" 100.00 286 100.00 100.00 0.00e+00
PDB 3HOD "Crystal Structure Of The Ppargamma-Lbd Complexed With A New Aryloxy-3phenylpropanoic Acid" 100.00 286 100.00 100.00 0.00e+00
PDB 3IA6 "X-Ray Crystal Structure Of The Nuclear Hormone Receptor Ppar-Gamma In A Complex With A Ppar GammaALPHA DUAL Agonist" 100.00 271 100.00 100.00 0.00e+00
PDB 3K8S "Crystal Structure Of Pparg In Complex With T2384" 100.00 272 100.00 100.00 0.00e+00
PDB 3KMG "The X-Ray Crystal Structure Of Ppar-Gamma In Complex With An Indole Derivative Modulator, Gsk538, And An Src-1 Peptide" 100.00 272 100.00 100.00 0.00e+00
PDB 3LMP "Crystal Structure Of The Ppargamma-Lbd Complexed With A Cercosporamide Derivative Modulator" 100.00 283 100.00 100.00 0.00e+00
PDB 3NOA "Crystal Structure Of Human Ppar-Gamma Ligand Binding Domain Complex With A Potency Improved Agonist" 100.00 271 100.00 100.00 0.00e+00
PDB 3OSI "Crystal Structure Of Ppargamma Ligand Binding Domain In Complex With Tetrachloro-bisphenol A (tcbpa)" 100.00 285 100.00 100.00 0.00e+00
PDB 3OSW "Crystal Structure Of Ppargamma Ligand Binding Domain In Complex With Tetrabromo-bisphenol A (tbbpa)" 100.00 285 100.00 100.00 0.00e+00
PDB 3PBA "Crystal Structure Of Ppargamma Ligand Binding Domain In Complex With Monosulfate Tetrabromo-Bisphenol A (Monotbbpa)" 100.00 286 100.00 100.00 0.00e+00
PDB 3PO9 "Crystal Structure Of Ppargamma Ligand Binding Domain In Complex With Tripropyltin" 100.00 286 100.00 100.00 0.00e+00
PDB 3PRG "Ligand Binding Domain Of Human Peroxisome Proliferator Activated Receptor" 100.00 278 100.00 100.00 0.00e+00
PDB 3QT0 "Revealing A Steroid Receptor Ligand As A Unique Ppargamma Agonist" 100.00 271 100.00 100.00 0.00e+00
PDB 3R5N "Crystal Structure Of Ppargammalbd Complexed With The Agonist Magnolol" 100.00 274 100.00 100.00 0.00e+00
PDB 3R8A "X-Ray Crystal Structure Of The Nuclear Hormone Receptor Ppar-Gamma In A Complex With A Compound With Dual Ppar Gamma Agonism An" 100.00 282 100.00 100.00 0.00e+00
PDB 3R8I "Crystal Structure Of Ppargamma With An Achiral Ureidofibrate Derivative (Rt86)" 100.00 287 100.00 100.00 0.00e+00
PDB 3S9S "Ligand Binding Domain Of Ppargamma Complexed With A Benzimidazole Partial Agonist" 100.00 284 100.00 100.00 0.00e+00
PDB 3SZ1 "Human Ppar Gamma Ligand Binding Domain In Complex With Luteolin And Myristic Acid" 100.00 278 100.00 100.00 0.00e+00
PDB 3T03 "Crystal Structure Of Ppar Gamma Ligand Binding Domain In Complex With A Novel Partial Agonist Gq-16" 100.00 284 100.00 100.00 0.00e+00
PDB 3TY0 "Structure Of Ppargamma Ligand Binding Domain In Complex With (r)-5-(3- ((3-(6-methoxybenzo[d]isoxazol-3-yl)-2-oxo-2,3-dihydro-1" 100.00 277 100.00 100.00 0.00e+00
PDB 3U9Q "Ligand Binding Domain Of Ppargamma Complexed With Decanoic Acid And Pgc-1a Peptide" 99.63 269 100.00 100.00 0.00e+00
PDB 3V9T "Crystal Structure Of The Ppargamma-Lbd Complexed With A Cercosporamide Derivative Modulator" 100.00 283 100.00 100.00 0.00e+00
PDB 3V9V "Crystal Structure Of The Ppargamma-Lbd Complexed With A Cercosporamide Derivative Modulator" 100.00 283 100.00 100.00 0.00e+00
PDB 3V9Y "Crystal Structure Of The Ppargamma-Lbd Complexed With A Cercosporamide Derivative Modulator" 100.00 283 100.00 100.00 0.00e+00
PDB 3VJH "Human Ppar Gamma Ligand Binding Domain In Complex With Jkpl35" 100.00 286 100.00 100.00 0.00e+00
PDB 3VJI "Human Ppar Gamma Ligand Binding Domain In Complex With Jkpl53" 100.00 286 100.00 100.00 0.00e+00
PDB 3VN2 "Crystal Structure Of Ppargamma Complexed With Telmisartan" 100.00 285 100.00 100.00 0.00e+00
PDB 3VSO "Human Ppar Gamma Ligand Binding Domain In Complex With A Gamma Selective Agonist Mekt21" 100.00 286 100.00 100.00 0.00e+00
PDB 3VSP "Human Ppar Gamma Ligand Binding Domain In Complex With A Gamma Selective Agonist Mekt28" 100.00 286 100.00 100.00 0.00e+00
PDB 3WJ4 "Crystal Structure Of Ppargamma Ligand Binding Domain In Complex With Tributyltin" 100.00 276 100.00 100.00 0.00e+00
PDB 3WJ5 "Crystal Structure Of Ppargamma Ligand Binding Domain In Complex With Triphenyltin" 100.00 276 100.00 100.00 0.00e+00
PDB 3WMH "Human Pprr Gamma Ligand Binding Domain In Complex With A Gammma Selective Synthetic Partial Agonist Mekt75" 100.00 286 100.00 100.00 0.00e+00
PDB 4A4V "Ligand Binding Domain Of Human Ppar Gamma In Complex With Amorfrutin 2" 100.00 287 100.00 100.00 0.00e+00
PDB 4A4W "Ligand Binding Domain Of Human Ppar Gamma In Complex With Amorfrutin 2" 100.00 287 100.00 100.00 0.00e+00
PDB 4E4K "Crystal Structure Of Ppargamma With The Ligand Jo21" 100.00 287 100.00 100.00 0.00e+00
PDB 4E4Q "Crystal Structure Of Ppargamma With The Ligand Fs214" 100.00 287 100.00 100.00 0.00e+00
PDB 4EM9 "Human Ppar Gamma In Complex With Nonanoic Acids" 100.00 275 100.00 100.00 0.00e+00
PDB 4EMA "Human Peroxisome Proliferator-activated Receptor Gamma In Complex With Rosiglitazone" 100.00 275 100.00 100.00 0.00e+00
PDB 4F9M "Crystal Structure Of The Ppargamma-Lbd Complexed With A Cercosporamide Derivative Modulator" 100.00 283 100.00 100.00 0.00e+00
PDB 4FGY "Identification Of A Unique Ppar Ligand With An Unexpected Binding Mode And Antibetic Activity" 100.00 270 100.00 100.00 0.00e+00
PDB 4HEE "Crystal Structure Of Ppargamma In Complex With Compound 13" 100.00 282 100.00 100.00 0.00e+00
PDB 4JAZ "Crystal Structure Of The Complex Between Ppargamma Lbd And Trans- Resveratrol" 100.00 287 100.00 100.00 0.00e+00
PDB 4JL4 "Crystal Structure Of The Complex Between Ppargamma Lbd And The Ligand Lj570 [(2s)-3-(biphenyl-4-yl)-2-(biphenyl-4-yloxy)propano" 100.00 287 100.00 100.00 0.00e+00
PDB 4L96 "Structure Of The Complex Between The F360l Ppargamma Mutant And The Ligand Lt175 (space Group I222)" 100.00 275 99.63 99.63 0.00e+00
PDB 4L98 "Crystal Structure Of The Complex Of F360l Ppargamma Mutant With The Ligand Lt175" 100.00 275 99.63 99.63 0.00e+00
PDB 4O8F "Crystal Structure Of The Complex Between Ppargamma Mutant R357a And Rosiglitazone" 100.00 287 99.63 99.63 0.00e+00
PDB 4PRG "0072 Partial Agonist Ppar Gamma Cocrystal" 100.00 270 100.00 100.00 0.00e+00
DBJ BAA18949 "PPAR gamma2 [Homo sapiens]" 100.37 506 99.63 99.63 0.00e+00
DBJ BAA23354 "peroxisome proliferator activated-receptor gamma [Homo sapiens]" 100.00 474 98.89 98.89 0.00e+00
DBJ BAA32540 "PPAR-gamma protein [Rattus norvegicus]" 100.00 475 98.52 99.63 0.00e+00
DBJ BAA36485 "PPAR gamma2 [Rattus norvegicus]" 100.00 505 98.52 99.63 0.00e+00
DBJ BAD20642 "peroxisome proliferator-activated receptor gamma 1a [Sus scrofa]" 100.00 475 99.63 100.00 0.00e+00
EMBL CAA07224 "peroxisome proliferator-cctivated receptor gamma 1 [Sus scrofa]" 100.00 475 98.89 99.63 0.00e+00
EMBL CAA07225 "peroxisome proliferator-activated receptor-gamma 2 [Sus scrofa]" 100.00 504 98.89 99.63 0.00e+00
EMBL CAA62152 "peroxisome proliferator activated receptor gamma [Homo sapiens]" 100.00 477 100.00 100.00 0.00e+00
EMBL CAA62153 "peroxisome proliferator activated receptor gamma [Homo sapiens]" 100.00 475 100.00 100.00 0.00e+00
EMBL CAA73032 "peroxisome proliferator activated receptor gamma 1 [Bos taurus]" 100.00 475 98.89 99.63 0.00e+00
GB AAA19971 "peroxisome proliferator-activated receptor gamma [Mus musculus]" 100.00 475 98.52 99.63 0.00e+00
GB AAA62110 "PPAR gamma [Mus musculus]" 100.00 475 97.41 98.89 0.00e+00
GB AAA62277 "peroxisome proliferator activated protein-gamma-2 [Mus musculus]" 100.00 505 98.15 99.63 0.00e+00
GB AAA80314 "peroxisome proliferator activated receptor gamma [Homo sapiens]" 100.00 477 100.00 100.00 0.00e+00
GB AAB04028 "peroxisome proliferator activated receptor gamma 2 [Homo sapiens]" 100.00 505 100.00 100.00 0.00e+00
PIR JE0279 "peroxisome proliferator-activated receptor gamma 1 - pig" 100.00 475 98.89 99.63 0.00e+00
REF NP_001019803 "peroxisome proliferator-activated receptor gamma [Canis lupus familiaris]" 100.00 505 100.00 100.00 0.00e+00
REF NP_001028032 "peroxisome proliferator-activated receptor gamma [Macaca mulatta]" 100.00 505 100.00 100.00 0.00e+00
REF NP_001075617 "peroxisome proliferator-activated receptor gamma [Oryctolagus cuniculus]" 100.00 475 98.89 100.00 0.00e+00
REF NP_001094391 "peroxisome proliferator-activated receptor gamma [Ovis aries]" 100.00 475 98.89 99.63 0.00e+00
REF NP_001106647 "peroxisome proliferator-activated receptor gamma [Felis catus]" 100.00 505 99.26 99.63 0.00e+00
SP O18924 "RecName: Full=Peroxisome proliferator-activated receptor gamma; Short=PPAR-gamma; AltName: Full=Nuclear receptor subfamily 1 gr" 100.00 505 100.00 100.00 0.00e+00
SP O18971 "RecName: Full=Peroxisome proliferator-activated receptor gamma; Short=PPAR-gamma; AltName: Full=Nuclear receptor subfamily 1 gr" 100.00 505 98.89 99.63 0.00e+00
SP O19052 "RecName: Full=Peroxisome proliferator-activated receptor gamma; Short=PPAR-gamma; AltName: Full=Nuclear receptor subfamily 1 gr" 100.00 475 98.89 100.00 0.00e+00
SP O62807 "RecName: Full=Peroxisome proliferator-activated receptor gamma; Short=PPAR-gamma; AltName: Full=Nuclear receptor subfamily 1 gr" 100.00 504 99.63 100.00 0.00e+00
SP O88275 "RecName: Full=Peroxisome proliferator-activated receptor gamma; Short=PPAR-gamma; AltName: Full=Nuclear receptor subfamily 1 gr" 100.00 505 98.52 99.63 0.00e+00
TPG DAA16769 "TPA: peroxisome proliferator-activated receptor gamma [Bos taurus]" 100.00 505 98.89 99.63 0.00e+00
stop_
save_
####################
# Natural source #
####################
save_natural_source
_Saveframe_category natural_source
loop_
_Mol_label
_Organism_name_common
_NCBI_taxonomy_ID
_Superkingdom
_Kingdom
_Genus
_Species
$Pparg Human 9606 Eukaryota Metazoa Homo sapiens
stop_
save_
#########################
# Experimental source #
#########################
save_experimental_source
_Saveframe_category experimental_source
loop_
_Mol_label
_Production_method
_Host_organism_name_common
_Genus
_Species
_Strain
_Vector_name
$Pparg 'recombinant technology' . . . . .
stop_
save_
#####################################
# Sample contents and methodology #
#####################################
########################
# Sample description #
########################
save_sample_1
_Saveframe_category sample
_Sample_type solution
_Details .
loop_
_Mol_label
_Concentration_value
_Concentration_value_units
_Isotopic_labeling
$LBD_Pparg . mM .
stop_
save_
#########################
# Experimental detail #
#########################
##################################
# NMR Spectrometer definitions #
##################################
save_NMR_spectrometer
_Saveframe_category NMR_spectrometer
_Manufacturer unknown
_Model unknown
_Field_strength 0
_Details 'spectrometer information not available'
save_
#############################
# NMR applied experiments #
#############################
save__1
_Saveframe_category NMR_applied_experiment
_Sample_label $sample_1
save_
#######################
# Sample conditions #
#######################
save_Ex-cond_1
_Saveframe_category sample_conditions
_Details .
loop_
_Variable_type
_Variable_value
_Variable_value_error
_Variable_value_units
pH 7.4 . pH
temperature 298 . K
stop_
save_
####################
# NMR parameters #
####################
##############################
# Assigned chemical shifts #
##############################
################################
# Chemical shift referencing #
################################
save_chemical_shift_reference
_Saveframe_category chemical_shift_reference
_Details .
loop_
_Mol_common_name
_Atom_type
_Atom_isotope_number
_Atom_group
_Chem_shift_units
_Chem_shift_value
_Reference_method
_Reference_type
_External_reference_sample_geometry
_External_reference_location
_External_reference_axis
_Indirect_shift_ratio
_Indirect_shift_ratio_citation_label
_Correction_value_citation_label
DSS C 13 . ppm . . . . . . 0.251449530 $entry_citation $entry_citation
DSS H 1 'methyl protons' ppm 0.0 internal direct . . . 1.0 $entry_citation $entry_citation
DSS N 15 . ppm . . . . . . 0.101329118 $entry_citation $entry_citation
stop_
save_
###################################
# Assigned chemical shift lists #
###################################
###################################################################
# Chemical Shift Ambiguity Index Value Definitions #
# #
# The values other than 1 are used for those atoms with different #
# chemical shifts that cannot be assigned to stereospecific atoms #
# or to specific residues or chains. #
# #
# Index Value Definition #
# #
# 1 Unique (including isolated methyl protons, #
# geminal atoms, and geminal methyl #
# groups with identical chemical shifts) #
# (e.g. ILE HD11, HD12, HD13 protons) #
# 2 Ambiguity of geminal atoms or geminal methyl #
# proton groups (e.g. ASP HB2 and HB3 #
# protons, LEU CD1 and CD2 carbons, or #
# LEU HD11, HD12, HD13 and HD21, HD22, #
# HD23 methyl protons) #
# 3 Aromatic atoms on opposite sides of #
# symmetrical rings (e.g. TYR HE1 and HE2 #
# protons) #
# 4 Intraresidue ambiguities (e.g. LYS HG and #
# HD protons or TRP HZ2 and HZ3 protons) #
# 5 Interresidue ambiguities (LYS 12 vs. LYS 27) #
# 6 Intermolecular ambiguities (e.g. ASP 31 CA #
# in monomer 1 and ASP 31 CA in monomer 2 #
# of an asymmetrical homodimer, duplex #
# DNA assignments, or other assignments #
# that may apply to atoms in one or more #
# molecule in the molecular assembly) #
# 9 Ambiguous, specific ambiguity not defined #
# #
###################################################################
save_shift_set_1
_Saveframe_category assigned_chemical_shifts
_Details .
loop_
_Sample_label
$sample_1
stop_
_Sample_conditions_label $Ex-cond_1
_Chem_shift_reference_set_label $chemical_shift_reference
_Mol_system_component_name 'LBD Pparg'
_Text_data_format .
_Text_data .
loop_
_Atom_shift_assign_ID
_Residue_author_seq_code
_Residue_seq_code
_Residue_label
_Atom_name
_Atom_type
_Chem_shift_value
_Chem_shift_value_error
_Chem_shift_ambiguity_code
1 . 2 SER CA C 58.54 . .
2 . 2 SER C C 176.76 . .
3 . 2 SER CB C 62.05 . .
4 . 3 ALA H H 7.58 . .
5 . 3 ALA N N 113.11 . .
6 . 3 ALA CA C 53.2 . .
7 . 3 ALA C C 179.35 . .
8 . 3 ALA CB C 17.33 . .
9 . 4 ASP H H 7.71 . .
10 . 4 ASP N N 120.07 . .
11 . 4 ASP CA C 54.23 . .
12 . 4 ASP C C 178.38 . .
13 . 4 ASP CB C 39.43 . .
14 . 5 LEU H H 7.88 . .
15 . 5 LEU N N 122.92 . .
16 . 5 LEU CA C 56.22 . .
17 . 5 LEU C C 181.05 . .
18 . 5 LEU CB C 40.57 . .
19 . 6 ARG H H 8.14 . .
20 . 6 ARG N N 121.16 . .
21 . 6 ARG CA C 56.21 . .
22 . 6 ARG C C 178.78 . .
23 . 6 ARG CB C 26.26 . .
24 . 7 ALA H H 7.94 . .
25 . 7 ALA N N 125.3 . .
26 . 7 ALA CA C 53.66 . .
27 . 7 ALA C C 180.56 . .
28 . 7 ALA CB C 16.68 . .
29 . 8 LEU H H 7.76 . .
30 . 8 LEU N N 121.87 . .
31 . 8 LEU CA C 56.51 . .
32 . 8 LEU C C 177.77 . .
33 . 8 LEU CB C 40.05 . .
34 . 9 ALA H H 7.38 . .
35 . 9 ALA N N 120.84 . .
36 . 9 ALA CA C 54.81 . .
37 . 9 ALA C C 177.44 . .
38 . 9 ALA CB C 17.97 . .
39 . 10 LYS H H 7.73 . .
40 . 10 LYS N N 120.4 . .
41 . 10 LYS CA C 58 . .
42 . 10 LYS C C 177.28 . .
43 . 10 LYS CB C 30.92 . .
44 . 11 HIS H H 8.15 . .
45 . 11 HIS N N 120.54 . .
46 . 11 HIS CA C 58.53 . .
47 . 11 HIS C C 179.22 . .
48 . 11 HIS CB C 30.14 . .
49 . 12 LEU H H 8.26 . .
50 . 12 LEU N N 119.46 . .
51 . 12 LEU CA C 56.22 . .
52 . 12 LEU C C 177.28 . .
53 . 12 LEU CB C 38.22 . .
54 . 13 TYR H H 8.09 . .
55 . 13 TYR N N 121.07 . .
56 . 13 TYR CA C 59.55 . .
57 . 13 TYR C C 176.34 . .
58 . 13 TYR CB C 36.18 . .
59 . 14 ASP H H 8.55 . .
60 . 14 ASP N N 120.12 . .
61 . 14 ASP CA C 56.32 . .
62 . 14 ASP C C 179.48 . .
63 . 14 ASP CB C 38.44 . .
64 . 15 SER H H 7.81 . .
65 . 15 SER N N 115.8 . .
66 . 15 SER CA C 59.98 . .
67 . 15 SER C C 176.11 . .
68 . 15 SER CB C 38.68 . .
69 . 16 TYR H H 8.92 . .
70 . 16 TYR N N 129.51 . .
71 . 16 TYR CA C 59.98 . .
72 . 16 TYR C C 176.14 . .
73 . 16 TYR CB C 37.64 . .
74 . 17 ILE H H 8.18 . .
75 . 17 ILE N N 118.37 . .
76 . 17 ILE CA C 60.53 . .
77 . 17 ILE C C 178.66 . .
78 . 17 ILE CB C 34.8 . .
79 . 18 LYS H H 7.04 . .
80 . 18 LYS N N 118.82 . .
81 . 18 LYS CA C 57.42 . .
82 . 18 LYS C C 177.85 . .
83 . 18 LYS CB C 31.43 . .
84 . 19 SER H H 7.32 . .
85 . 19 SER N N 114.93 . .
86 . 19 SER CA C 60.27 . .
87 . 19 SER C C 178.33 . .
88 . 19 SER CB C 63.22 . .
89 . 20 PHE H H 7.2 . .
90 . 20 PHE N N 118.91 . .
91 . 20 PHE CA C 52.56 . .
92 . 20 PHE CB C 36.87 . .
93 . 21 PRO CA C 63.12 . .
94 . 21 PRO C C 177.26 . .
95 . 21 PRO CB C 30.86 . .
96 . 22 LEU H H 7.6 . .
97 . 22 LEU N N 120.01 . .
98 . 22 LEU CA C 52.19 . .
99 . 22 LEU C C 174.61 . .
100 . 22 LEU CB C 39.46 . .
101 . 23 THR H H 6.74 . .
102 . 23 THR N N 115.63 . .
103 . 23 THR CA C 59.15 . .
104 . 23 THR C C 173.52 . .
105 . 23 THR CB C 68.92 . .
106 . 24 LYS H H 10.4 . .
107 . 24 LYS N N 125.24 . .
108 . 24 LYS CA C 59.43 . .
109 . 24 LYS C C 178.72 . .
110 . 24 LYS CB C 31.43 . .
111 . 25 ALA H H 9.08 . .
112 . 25 ALA N N 121.33 . .
113 . 25 ALA CA C 53.95 . .
114 . 25 ALA C C 181.39 . .
115 . 25 ALA CB C 16.37 . .
116 . 26 LYS H H 7.46 . .
117 . 26 LYS N N 119.24 . .
118 . 26 LYS CA C 57.99 . .
119 . 26 LYS C C 174.36 . .
120 . 26 LYS CB C 31.22 . .
121 . 27 ALA H H 8.23 . .
122 . 27 ALA N N 122.81 . .
123 . 27 ALA CA C 53.95 . .
124 . 27 ALA C C 179.55 . .
125 . 27 ALA CB C 18.24 . .
126 . 28 ARG H H 9.02 . .
127 . 28 ARG N N 116.12 . .
128 . 28 ARG CA C 56.78 . .
129 . 28 ARG C C 179.27 . .
130 . 28 ARG CB C 26.78 . .
131 . 29 ALA H H 7.33 . .
132 . 29 ALA N N 123.51 . .
133 . 29 ALA CA C 53.95 . .
134 . 29 ALA C C 173.21 . .
135 . 29 ALA CB C 16.42 . .
136 . 30 ILE H H 7.45 . .
137 . 30 ILE N N 119.2 . .
138 . 30 ILE CA C 63.99 . .
139 . 30 ILE CB C 40.24 . .
140 . 31 LEU H H 8.26 . .
141 . 31 LEU N N 119.46 . .
142 . 31 LEU CA C 56.44 . .
143 . 31 LEU C C 178.41 . .
144 . 31 LEU CB C 41.01 . .
145 . 32 THR H H 7.6 . .
146 . 32 THR N N 107.61 . .
147 . 32 THR CA C 60.87 . .
148 . 32 THR C C 175.35 . .
149 . 32 THR CB C 70 . .
150 . 33 GLY H H 7.34 . .
151 . 33 GLY N N 110.76 . .
152 . 33 GLY CA C 44.95 . .
153 . 33 GLY C C 174.52 . .
154 . 34 LYS H H 8.01 . .
155 . 34 LYS N N 121.1 . .
156 . 34 LYS CA C 54.93 . .
157 . 34 LYS C C 176.6 . .
158 . 34 LYS CB C 30.88 . .
159 . 35 THR H H 7.58 . .
160 . 35 THR N N 113.11 . .
161 . 35 THR CA C 59.99 . .
162 . 35 THR C C 174.52 . .
163 . 35 THR CB C 68.65 . .
164 . 36 THR H H 7.93 . .
165 . 36 THR N N 121.92 . .
166 . 36 THR CA C 59.11 . .
167 . 36 THR CB C 68.61 . .
168 . 37 ASP CA C 56.41 . .
169 . 37 ASP C C 177.97 . .
170 . 37 ASP CB C 40.7 . .
171 . 38 LYS H H 7.93 . .
172 . 38 LYS N N 119.29 . .
173 . 38 LYS CA C 54.26 . .
174 . 38 LYS C C 178.18 . .
175 . 38 LYS CB C 31.53 . .
176 . 39 SER H H 8.03 . .
177 . 39 SER N N 118.92 . .
178 . 39 SER CA C 55.77 . .
179 . 39 SER CB C 61.79 . .
180 . 40 PRO CA C 61.4 . .
181 . 40 PRO C C 175.47 . .
182 . 40 PRO CB C 30.01 . .
183 . 41 PHE H H 7.84 . .
184 . 41 PHE N N 124.39 . .
185 . 41 PHE CA C 57.45 . .
186 . 41 PHE C C 174.74 . .
187 . 41 PHE CB C 39 . .
188 . 42 VAL H H 7.78 . .
189 . 42 VAL N N 130.06 . .
190 . 42 VAL CA C 61.64 . .
191 . 42 VAL C C 174.39 . .
192 . 42 VAL CB C 30.69 . .
193 . 43 ILE H H 9.02 . .
194 . 43 ILE N N 128.55 . .
195 . 43 ILE CA C 59.96 . .
196 . 43 ILE CB C 37.65 . .
197 . 47 ASN CA C 57.19 . .
198 . 47 ASN C C 177.31 . .
199 . 47 ASN CB C 40 . .
200 . 48 SER H H 8.64 . .
201 . 48 SER N N 117.39 . .
202 . 48 SER CA C 57.1 . .
203 . 48 SER CB C 60.64 . .
204 . 51 MET CA C 56.15 . .
205 . 51 MET C C 175.69 . .
206 . 51 MET CB C 26.2 . .
207 . 52 GLY H H 7.63 . .
208 . 52 GLY N N 104.24 . .
209 . 52 GLY CA C 43.51 . .
210 . 53 GLU CA C 53.93 . .
211 . 53 GLU CB C 30.92 . .
212 . 54 ASP H H 8.35 . .
213 . 54 ASP N N 119.49 . .
214 . 54 ASP CA C 57.68 . .
215 . 54 ASP C C 179.75 . .
216 . 54 ASP CB C 40.75 . .
217 . 55 LYS H H 7.8 . .
218 . 55 LYS N N 119.85 . .
219 . 55 LYS CA C 58 . .
220 . 55 LYS CB C 27.81 . .
221 . 58 PHE CA C 56.31 . .
222 . 58 PHE C C 178.93 . .
223 . 58 PHE CB C 39.66 . .
224 . 59 LYS H H 7.47 . .
225 . 59 LYS N N 117.93 . .
226 . 59 LYS CA C 57.13 . .
227 . 59 LYS C C 178.57 . .
228 . 59 LYS CB C 26.78 . .
229 . 60 HIS H H 7.15 . .
230 . 60 HIS N N 121.37 . .
231 . 60 HIS CA C 65.15 . .
232 . 60 HIS CB C 29.72 . .
233 . 61 ILE H H 8.06 . .
234 . 61 ILE N N 122.92 . .
235 . 61 ILE CA C 64.85 . .
236 . 61 ILE CB C 36.04 . .
237 . 63 PRO CA C 61.94 . .
238 . 63 PRO CB C 30.66 . .
239 . 64 LEU H H 8.07 . .
240 . 64 LEU N N 122.59 . .
241 . 64 LEU CA C 54.01 . .
242 . 64 LEU C C 177.24 . .
243 . 64 LEU CB C 40.67 . .
244 . 65 GLN H H 8.04 . .
245 . 65 GLN N N 121.98 . .
246 . 65 GLN CA C 54.11 . .
247 . 65 GLN C C 175.38 . .
248 . 65 GLN CB C 28.53 . .
249 . 66 GLU H H 7.79 . .
250 . 66 GLU N N 128.3 . .
251 . 66 GLU CA C 56.72 . .
252 . 66 GLU CB C 29.8 . .
253 . 70 GLU CA C 54.42 . .
254 . 70 GLU C C 176.76 . .
255 . 70 GLU CB C 28.58 . .
256 . 71 VAL H H 8.36 . .
257 . 71 VAL N N 125.97 . .
258 . 71 VAL CA C 65.4 . .
259 . 71 VAL C C 176.84 . .
260 . 71 VAL CB C 30.01 . .
261 . 72 ALA H H 8.54 . .
262 . 72 ALA N N 120.55 . .
263 . 72 ALA CA C 54.52 . .
264 . 72 ALA C C 177.97 . .
265 . 72 ALA CB C 17.33 . .
266 . 73 ILE H H 6.34 . .
267 . 73 ILE N N 114.29 . .
268 . 73 ILE CA C 61.68 . .
269 . 73 ILE C C 179.51 . .
270 . 73 ILE CB C 35.32 . .
271 . 74 ARG H H 7.72 . .
272 . 74 ARG N N 120.98 . .
273 . 74 ARG CA C 58.8 . .
274 . 74 ARG C C 180.11 . .
275 . 74 ARG CB C 28.85 . .
276 . 75 ILE H H 8.1 . .
277 . 75 ILE N N 120.08 . .
278 . 75 ILE CA C 63.12 . .
279 . 75 ILE C C 178.23 . .
280 . 75 ILE CB C 34.88 . .
281 . 76 PHE H H 7.76 . .
282 . 76 PHE N N 121.93 . .
283 . 76 PHE CA C 59.75 . .
284 . 76 PHE C C 177.81 . .
285 . 76 PHE CB C 37.91 . .
286 . 77 GLN H H 8.72 . .
287 . 77 GLN N N 118.25 . .
288 . 77 GLN CA C 58.25 . .
289 . 77 GLN C C 177.65 . .
290 . 77 GLN CB C 27.03 . .
291 . 78 GLY H H 7.76 . .
292 . 78 GLY N N 109.12 . .
293 . 78 GLY CA C 46.1 . .
294 . 78 GLY C C 175.17 . .
295 . 79 CYS H H 7.27 . .
296 . 79 CYS N N 120.55 . .
297 . 79 CYS CA C 62.54 . .
298 . 79 CYS C C 175.85 . .
299 . 79 CYS CB C 23.83 . .
300 . 80 GLN H H 7.17 . .
301 . 80 GLN N N 118.8 . .
302 . 80 GLN CA C 58.83 . .
303 . 80 GLN C C 176.97 . .
304 . 81 PHE H H 7.89 . .
305 . 81 PHE N N 117.77 . .
306 . 81 PHE CA C 59.75 . .
307 . 81 PHE C C 178.44 . .
308 . 81 PHE CB C 36.35 . .
309 . 82 ARG H H 7.57 . .
310 . 82 ARG N N 121.06 . .
311 . 82 ARG CA C 56.5 . .
312 . 82 ARG C C 177.89 . .
313 . 82 ARG CB C 27.03 . .
314 . 83 SER H H 8.07 . .
315 . 83 SER N N 118.09 . .
316 . 83 SER CA C 60.84 . .
317 . 83 SER C C 175.33 . .
318 . 83 SER CB C 62.4 . .
319 . 84 VAL H H 7.63 . .
320 . 84 VAL N N 120.19 . .
321 . 84 VAL CA C 65.96 . .
322 . 84 VAL C C 178.15 . .
323 . 84 VAL CB C 29.36 . .
324 . 85 GLU H H 7.17 . .
325 . 85 GLU N N 120.22 . .
326 . 85 GLU CA C 57.96 . .
327 . 85 GLU C C 178.94 . .
328 . 85 GLU CB C 29.62 . .
329 . 86 ALA H H 8.49 . .
330 . 86 ALA N N 123.87 . .
331 . 86 ALA CA C 53.28 . .
332 . 86 ALA C C 179.8 . .
333 . 86 ALA CB C 16.43 . .
334 . 87 VAL H H 8.66 . .
335 . 87 VAL N N 118.96 . .
336 . 87 VAL CA C 65.96 . .
337 . 87 VAL C C 179.46 . .
338 . 87 VAL CB C 30.01 . .
339 . 88 GLN H H 7.37 . .
340 . 88 GLN N N 119.02 . .
341 . 88 GLN CA C 58.1 . .
342 . 88 GLN C C 175.69 . .
343 . 88 GLN CB C 26.11 . .
344 . 89 GLU H H 7.24 . .
345 . 89 GLU N N 121.45 . .
346 . 89 GLU CA C 57.96 . .
347 . 89 GLU CB C 27.67 . .
348 . 90 ILE H H 8.67 . .
349 . 90 ILE N N 118.4 . .
350 . 90 ILE CA C 63.99 . .
351 . 90 ILE C C 172.53 . .
352 . 90 ILE CB C 37.33 . .
353 . 91 THR H H 7.97 . .
354 . 91 THR N N 117.34 . .
355 . 91 THR CA C 66.34 . .
356 . 91 THR C C 177.89 . .
357 . 91 THR CB C 67.46 . .
358 . 92 GLU H H 7.25 . .
359 . 92 GLU N N 120.81 . .
360 . 92 GLU CA C 57.67 . .
361 . 92 GLU C C 175.46 . .
362 . 92 GLU CB C 27.55 . .
363 . 93 TYR H H 7.79 . .
364 . 93 TYR N N 121.68 . .
365 . 93 TYR CA C 60.27 . .
366 . 93 TYR C C 178.46 . .
367 . 93 TYR CB C 37.85 . .
368 . 94 ALA H H 8.75 . .
369 . 94 ALA N N 123.43 . .
370 . 94 ALA CA C 53.09 . .
371 . 94 ALA C C 177.94 . .
372 . 94 ALA CB C 15.99 . .
373 . 95 LYS H H 6.97 . .
374 . 95 LYS N N 111.56 . .
375 . 95 LYS CA C 57.42 . .
376 . 95 LYS C C 179.01 . .
377 . 95 LYS CB C 30.66 . .
378 . 96 SER H H 7.62 . .
379 . 96 SER N N 117.38 . .
380 . 96 SER CA C 57.68 . .
381 . 96 SER C C 174.74 . .
382 . 96 SER CB C 62.5 . .
383 . 97 ILE H H 7.48 . .
384 . 97 ILE N N 128.29 . .
385 . 97 ILE CA C 59.1 . .
386 . 97 ILE CB C 36.87 . .
387 . 98 PRO CA C 63.7 . .
388 . 98 PRO C C 175.95 . .
389 . 98 PRO CB C 29.74 . .
390 . 99 GLY H H 8.45 . .
391 . 99 GLY N N 112.67 . .
392 . 99 GLY CA C 43.8 . .
393 . 99 GLY C C 176.27 . .
394 . 100 PHE H H 8.06 . .
395 . 100 PHE N N 124.64 . .
396 . 100 PHE CA C 61.76 . .
397 . 100 PHE C C 176.71 . .
398 . 100 PHE CB C 39.46 . .
399 . 101 VAL H H 8.01 . .
400 . 101 VAL N N 107.41 . .
401 . 101 VAL CA C 61.93 . .
402 . 101 VAL C C 175.64 . .
403 . 101 VAL CB C 29.88 . .
404 . 102 ASN H H 6.89 . .
405 . 102 ASN N N 116.99 . .
406 . 102 ASN CA C 51.73 . .
407 . 102 ASN C C 175.59 . .
408 . 102 ASN CB C 37.91 . .
409 . 103 LEU H H 6.97 . .
410 . 103 LEU N N 121.24 . .
411 . 103 LEU CA C 53.06 . .
412 . 103 LEU C C 177.26 . .
413 . 103 LEU CB C 40.5 . .
414 . 104 ASP H H 8.89 . .
415 . 104 ASP N N 124.44 . .
416 . 104 ASP CA C 54.23 . .
417 . 104 ASP C C 177.25 . .
418 . 104 ASP CB C 41.79 . .
419 . 105 LEU H H 8.4 . .
420 . 105 LEU N N 128.71 . .
421 . 105 LEU CA C 57.37 . .
422 . 105 LEU CB C 40.5 . .
423 . 106 ASN H H 8.51 . .
424 . 106 ASN N N 115.91 . .
425 . 106 ASN CA C 55.47 . .
426 . 106 ASN C C 177.73 . .
427 . 106 ASN CB C 36.87 . .
428 . 107 ASP H H 7.33 . .
429 . 107 ASP N N 121.12 . .
430 . 107 ASP CA C 55.66 . .
431 . 107 ASP C C 177.65 . .
432 . 107 ASP CB C 38.17 . .
433 . 108 GLN H H 7.84 . .
434 . 108 GLN N N 120.06 . .
435 . 108 GLN CA C 59.12 . .
436 . 108 GLN C C 176.22 . .
437 . 108 GLN CB C 27.55 . .
438 . 109 VAL H H 7.28 . .
439 . 109 VAL N N 117.18 . .
440 . 109 VAL CA C 65.38 . .
441 . 109 VAL C C 174.7 . .
442 . 109 VAL CB C 30.03 . .
443 . 110 THR H H 8.14 . .
444 . 110 THR N N 121.13 . .
445 . 110 THR CA C 65.76 . .
446 . 110 THR C C 176.37 . .
447 . 110 THR CB C 67.05 . .
448 . 111 LEU H H 8.7 . .
449 . 111 LEU N N 120.42 . .
450 . 111 LEU CA C 56.79 . .
451 . 111 LEU C C 182.1 . .
452 . 111 LEU CB C 38.68 . .
453 . 112 LEU H H 7.91 . .
454 . 112 LEU N N 120.84 . .
455 . 112 LEU CA C 57.08 . .
456 . 112 LEU C C 176.95 . .
457 . 112 LEU CB C 39.98 . .
458 . 113 LYS H H 8.52 . .
459 . 113 LYS N N 122.5 . .
460 . 113 LYS CA C 59.15 . .
461 . 113 LYS C C 175.88 . .
462 . 113 LYS CB C 32.21 . .
463 . 114 TYR H H 7.25 . .
464 . 114 TYR N N 109.57 . .
465 . 114 TYR CA C 59.12 . .
466 . 114 TYR C C 176.58 . .
467 . 114 TYR CB C 38.42 . .
468 . 115 GLY H H 7.86 . .
469 . 115 GLY N N 106.64 . .
470 . 115 GLY CA C 44.95 . .
471 . 115 GLY C C 175.8 . .
472 . 116 VAL H H 8.04 . .
473 . 116 VAL N N 115.42 . .
474 . 116 VAL CA C 66.53 . .
475 . 116 VAL C C 177.08 . .
476 . 116 VAL CB C 29.87 . .
477 . 117 HIS H H 8.79 . .
478 . 117 HIS N N 118.21 . .
479 . 117 HIS CA C 63.13 . .
480 . 117 HIS C C 180.09 . .
481 . 117 HIS CB C 28.55 . .
482 . 118 GLU H H 6.83 . .
483 . 118 GLU N N 118.66 . .
484 . 118 GLU CA C 58.53 . .
485 . 118 GLU C C 179.27 . .
486 . 118 GLU CB C 28.33 . .
487 . 119 ILE H H 7.62 . .
488 . 119 ILE N N 120.07 . .
489 . 119 ILE CA C 63.49 . .
490 . 119 ILE C C 177.08 . .
491 . 119 ILE CB C 35.49 . .
492 . 120 ILE H H 8.65 . .
493 . 120 ILE N N 123.95 . .
494 . 120 ILE CA C 64.85 . .
495 . 120 ILE CB C 35.55 . .
496 . 121 TYR H H 7.63 . .
497 . 121 TYR N N 116.67 . .
498 . 121 TYR CA C 59.12 . .
499 . 121 TYR C C 178.33 . .
500 . 121 TYR CB C 34.54 . .
501 . 122 THR H H 7.22 . .
502 . 122 THR N N 119.03 . .
503 . 122 THR CA C 67.49 . .
504 . 123 MET CA C 57.35 . .
505 . 123 MET C C 176.19 . .
506 . 123 MET CB C 30.92 . .
507 . 124 LEU H H 8.4 . .
508 . 124 LEU N N 123.21 . .
509 . 124 LEU CA C 56.1 . .
510 . 124 LEU C C 178.88 . .
511 . 124 LEU CB C 40.75 . .
512 . 125 ALA H H 6.99 . .
513 . 125 ALA N N 119.11 . .
514 . 125 ALA CA C 54.81 . .
515 . 125 ALA C C 179.3 . .
516 . 125 ALA CB C 15.63 . .
517 . 126 SER H H 7.07 . .
518 . 126 SER N N 112.65 . .
519 . 126 SER CA C 59.98 . .
520 . 126 SER C C 179.46 . .
521 . 126 SER CB C 62.09 . .
522 . 127 LEU H H 7.41 . .
523 . 127 LEU N N 119.17 . .
524 . 127 LEU CA C 53.34 . .
525 . 127 LEU C C 174.57 . .
526 . 127 LEU CB C 40.39 . .
527 . 128 MET H H 7.29 . .
528 . 128 MET N N 117.8 . .
529 . 128 MET CA C 53.91 . .
530 . 128 MET C C 176.53 . .
531 . 128 MET CB C 36.09 . .
532 . 129 ASN H H 8.63 . .
533 . 129 ASN N N 118.72 . .
534 . 129 ASN CA C 50.58 . .
535 . 129 ASN CB C 39.2 . .
536 . 130 LYS H H 8.15 . .
537 . 130 LYS N N 112.8 . .
538 . 130 LYS CA C 57 . .
539 . 130 LYS C C 175.54 . .
540 . 130 LYS CB C 30.01 . .
541 . 131 ASP H H 8.12 . .
542 . 131 ASP N N 116.09 . .
543 . 131 ASP CA C 53.88 . .
544 . 131 ASP C C 177.78 . .
545 . 131 ASP CB C 42.05 . .
546 . 132 GLY H H 8.01 . .
547 . 132 GLY N N 112 . .
548 . 132 GLY CA C 46.68 . .
549 . 132 GLY C C 180.32 . .
550 . 133 VAL H H 7.89 . .
551 . 133 VAL N N 116.69 . .
552 . 133 VAL CA C 55.89 . .
553 . 133 VAL C C 172.15 . .
554 . 133 VAL CB C 35.32 . .
555 . 134 LEU H H 8.42 . .
556 . 134 LEU N N 128 . .
557 . 134 LEU CA C 53.92 . .
558 . 134 LEU C C 175.17 . .
559 . 134 LEU CB C 42.57 . .
560 . 135 ILE H H 8.16 . .
561 . 135 ILE N N 113.54 . .
562 . 135 ILE CA C 57.37 . .
563 . 135 ILE CB C 40.24 . .
564 . 137 GLU CA C 56.8 . .
565 . 137 GLU C C 178.26 . .
566 . 137 GLU CB C 31.71 . .
567 . 138 GLY H H 8.33 . .
568 . 138 GLY N N 109.76 . .
569 . 138 GLY CA C 45.24 . .
570 . 138 GLY C C 175.8 . .
571 . 139 GLN H H 8.01 . .
572 . 139 GLN N N 121 . .
573 . 139 GLN CA C 58.25 . .
574 . 139 GLN C C 176.61 . .
575 . 139 GLN CB C 28.32 . .
576 . 140 GLY H H 7.72 . .
577 . 140 GLY N N 136.67 . .
578 . 140 GLY CA C 42.08 . .
579 . 140 GLY C C 170.8 . .
580 . 141 PHE H H 8.74 . .
581 . 141 PHE N N 123.64 . .
582 . 141 PHE CA C 55.44 . .
583 . 141 PHE C C 172.55 . .
584 . 141 PHE CB C 41.27 . .
585 . 142 MET H H 8.73 . .
586 . 142 MET N N 128.88 . .
587 . 142 MET CA C 52.47 . .
588 . 142 MET C C 175.14 . .
589 . 142 MET CB C 34.54 . .
590 . 143 THR H H 8.33 . .
591 . 143 THR N N 116.41 . .
592 . 143 THR CA C 60.87 . .
593 . 143 THR C C 174.12 . .
594 . 143 THR CB C 68.63 . .
595 . 144 ARG H H 8.48 . .
596 . 144 ARG N N 126.74 . .
597 . 144 ARG CA C 57.65 . .
598 . 144 ARG CB C 29.88 . .
599 . 145 GLU H H 8.36 . .
600 . 145 GLU N N 118.6 . .
601 . 145 GLU CA C 57.67 . .
602 . 145 GLU C C 179.01 . .
603 . 145 GLU CB C 28.07 . .
604 . 146 PHE H H 7.79 . .
605 . 146 PHE N N 122.06 . .
606 . 146 PHE CA C 59.75 . .
607 . 146 PHE C C 178.96 . .
608 . 146 PHE CB C 37.39 . .
609 . 147 LEU H H 7.43 . .
610 . 147 LEU N N 121.47 . .
611 . 147 LEU CA C 57.08 . .
612 . 147 LEU C C 177.29 . .
613 . 147 LEU CB C 40.07 . .
614 . 148 LYS H H 7.54 . .
615 . 148 LYS N N 116.89 . .
616 . 148 LYS CA C 56.56 . .
617 . 148 LYS C C 180.14 . .
618 . 148 LYS CB C 31.43 . .
619 . 149 SER H H 7.34 . .
620 . 149 SER N N 114.44 . .
621 . 149 SER CA C 57.97 . .
622 . 149 SER C C 174.02 . .
623 . 149 SER CB C 62.24 . .
624 . 150 LEU H H 6.59 . .
625 . 150 LEU N N 122.62 . .
626 . 150 LEU CA C 53.34 . .
627 . 150 LEU C C 179.2 . .
628 . 150 LEU CB C 40.5 . .
629 . 151 ARG H H 8.36 . .
630 . 151 ARG N N 119.8 . .
631 . 151 ARG CA C 53.91 . .
632 . 151 ARG C C 176.22 . .
633 . 151 ARG CB C 28.33 . .
634 . 152 LYS H H 8.42 . .
635 . 152 LYS N N 124 . .
636 . 152 LYS CA C 54.26 . .
637 . 152 LYS CB C 30.14 . .
638 . 153 PRO CA C 62.55 . .
639 . 153 PRO C C 175.33 . .
640 . 153 PRO CB C 31.02 . .
641 . 154 PHE H H 8.3 . .
642 . 154 PHE N N 124 . .
643 . 154 PHE CA C 60.33 . .
644 . 154 PHE C C 176.42 . .
645 . 154 PHE CB C 37.65 . .
646 . 155 GLY H H 7.16 . .
647 . 155 GLY N N 107.12 . .
648 . 155 GLY CA C 45.53 . .
649 . 155 GLY C C 174.44 . .
650 . 156 ASP H H 7.34 . .
651 . 156 ASP N N 118.28 . .
652 . 156 ASP CA C 53.36 . .
653 . 156 ASP C C 177.97 . .
654 . 156 ASP CB C 40.75 . .
655 . 157 PHE H H 7.52 . .
656 . 157 PHE N N 119.9 . .
657 . 157 PHE CA C 59.46 . .
658 . 157 PHE C C 175.98 . .
659 . 157 PHE CB C 38.42 . .
660 . 158 MET H H 8.52 . .
661 . 158 MET N N 117.47 . .
662 . 158 MET CA C 52.76 . .
663 . 158 MET C C 178.86 . .
664 . 158 MET CB C 29.62 . .
665 . 159 GLU H H 7.88 . .
666 . 159 GLU N N 125.3 . .
667 . 159 GLU CA C 59.68 . .
668 . 159 GLU CB C 26.52 . .
669 . 160 PRO CA C 64.23 . .
670 . 160 PRO CB C 30.3 . .
671 . 161 LYS H H 7 . .
672 . 161 LYS N N 118.09 . .
673 . 161 LYS CA C 59.72 . .
674 . 161 LYS C C 177.97 . .
675 . 161 LYS CB C 29.74 . .
676 . 162 PHE H H 7.83 . .
677 . 162 PHE N N 119.68 . .
678 . 162 PHE CA C 61.76 . .
679 . 162 PHE C C 177.1 . .
680 . 162 PHE CB C 37.62 . .
681 . 163 GLU H H 8.12 . .
682 . 163 GLU N N 117.95 . .
683 . 163 GLU CA C 57.96 . .
684 . 163 GLU C C 178.46 . .
685 . 163 GLU CB C 28.07 . .
686 . 164 PHE H H 7.4 . .
687 . 164 PHE N N 119.07 . .
688 . 164 PHE CA C 60.04 . .
689 . 164 PHE C C 176.6 . .
690 . 164 PHE CB C 37.42 . .
691 . 165 ALA H H 8.31 . .
692 . 165 ALA N N 123.48 . .
693 . 165 ALA CA C 54.52 . .
694 . 165 ALA C C 178.7 . .
695 . 165 ALA CB C 19.79 . .
696 . 166 VAL H H 8.11 . .
697 . 166 VAL N N 116.74 . .
698 . 166 VAL CA C 65.1 . .
699 . 166 VAL C C 179.38 . .
700 . 166 VAL CB C 28.26 . .
701 . 167 LYS H H 6.62 . .
702 . 167 LYS N N 119.14 . .
703 . 167 LYS CA C 57.42 . .
704 . 167 LYS C C 178.41 . .
705 . 167 LYS CB C 31.18 . .
706 . 168 PHE H H 8.69 . .
707 . 168 PHE N N 123.58 . .
708 . 168 PHE CA C 60.61 . .
709 . 168 PHE C C 179.22 . .
710 . 168 PHE CB C 39.2 . .
711 . 169 ASN H H 9.32 . .
712 . 169 ASN N N 120.37 . .
713 . 169 ASN CA C 53.45 . .
714 . 169 ASN C C 178.78 . .
715 . 169 ASN CB C 35.84 . .
716 . 170 ALA H H 6.88 . .
717 . 170 ALA N N 123.8 . .
718 . 170 ALA CA C 52.51 . .
719 . 170 ALA C C 177.84 . .
720 . 170 ALA CB C 16.68 . .
721 . 171 LEU H H 7.02 . .
722 . 171 LEU N N 116.39 . .
723 . 171 LEU CA C 54.49 . .
724 . 171 LEU C C 175.75 . .
725 . 171 LEU CB C 38.68 . .
726 . 172 GLU H H 7.16 . .
727 . 172 GLU N N 110.24 . .
728 . 172 GLU CA C 55.08 . .
729 . 172 GLU C C 175.17 . .
730 . 172 GLU CB C 25.48 . .
731 . 173 LEU H H 7.79 . .
732 . 173 LEU N N 116.72 . .
733 . 173 LEU CA C 53.63 . .
734 . 173 LEU C C 178.14 . .
735 . 173 LEU CB C 39.98 . .
736 . 174 ASP H H 9.42 . .
737 . 174 ASP N N 123.31 . .
738 . 174 ASP CA C 50.16 . .
739 . 174 ASP C C 178.78 . .
740 . 174 ASP CB C 41.79 . .
741 . 175 ASP H H 8.58 . .
742 . 175 ASP N N 116.47 . .
743 . 175 ASP CA C 57.49 . .
744 . 175 ASP C C 175.88 . .
745 . 175 ASP CB C 42.65 . .
746 . 176 SER H H 7.97 . .
747 . 176 SER N N 116.46 . .
748 . 176 SER CA C 60.55 . .
749 . 176 SER C C 177.49 . .
750 . 177 ASP H H 7.66 . .
751 . 177 ASP N N 125.7 . .
752 . 177 ASP CA C 57.68 . .
753 . 177 ASP C C 176.61 . .
754 . 177 ASP CB C 38.42 . .
755 . 178 LEU H H 8.57 . .
756 . 178 LEU N N 117.23 . .
757 . 178 LEU CA C 57.37 . .
758 . 178 LEU C C 177.65 . .
759 . 178 LEU CB C 38.11 . .
760 . 179 ALA H H 7.65 . .
761 . 179 ALA N N 117.81 . .
762 . 180 ILE CA C 54.45 . .
763 . 180 ILE C C 174.65 . .
764 . 180 ILE CB C 38.63 . .
765 . 181 PHE H H 7.37 . .
766 . 181 PHE N N 122.14 . .
767 . 181 PHE CA C 55.39 . .
768 . 181 PHE C C 175.82 . .
769 . 181 PHE CB C 41.27 . .
770 . 182 ILE H H 7.29 . .
771 . 182 ILE N N 121.62 . .
772 . 182 ILE CA C 58.52 . .
773 . 182 ILE CB C 39.72 . .
774 . 186 ILE CA C 64.54 . .
775 . 186 ILE C C 177.33 . .
776 . 186 ILE CB C 35 . .
777 . 187 LEU H H 7.29 . .
778 . 187 LEU N N 126 . .
779 . 187 LEU CA C 50.47 . .
780 . 187 LEU C C 173 . .
781 . 187 LEU CB C 34.54 . .
782 . 188 SER H H 6.67 . .
783 . 188 SER N N 114.19 . .
784 . 188 SER CA C 57.39 . .
785 . 188 SER C C 173.89 . .
786 . 188 SER CB C 62.76 . .
787 . 189 GLY H H 8.37 . .
788 . 189 GLY N N 111.85 . .
789 . 189 GLY CA C 44.38 . .
790 . 189 GLY C C 168.5 . .
791 . 190 ASP H H 7.95 . .
792 . 190 ASP N N 117.02 . .
793 . 190 ASP CA C 51.06 . .
794 . 190 ASP C C 176.45 . .
795 . 190 ASP CB C 38.42 . .
796 . 191 ARG H H 6.43 . .
797 . 191 ARG N N 116.57 . .
798 . 191 ARG CA C 51.03 . .
799 . 191 ARG CB C 26 . .
800 . 192 PRO CA C 61.68 . .
801 . 192 PRO C C 177.1 . .
802 . 193 GLY H H 8.19 . .
803 . 193 GLY N N 107.61 . .
804 . 193 GLY CA C 44.09 . .
805 . 193 GLY C C 175.8 . .
806 . 194 LEU H H 6.59 . .
807 . 194 LEU N N 120.27 . .
808 . 194 LEU CA C 53.53 . .
809 . 194 LEU C C 176.92 . .
810 . 194 LEU CB C 41.53 . .
811 . 195 LEU H H 11.54 . .
812 . 195 LEU N N 128.55 . .
813 . 195 LEU CA C 55.64 . .
814 . 195 LEU C C 178.52 . .
815 . 195 LEU CB C 41.01 . .
816 . 196 ASN H H 8.8 . .
817 . 196 ASN N N 120.42 . .
818 . 196 ASN CA C 50 . .
819 . 196 ASN C C 176.24 . .
820 . 196 ASN CB C 37.13 . .
821 . 197 VAL H H 8.14 . .
822 . 197 VAL N N 122.65 . .
823 . 197 VAL CA C 65.1 . .
824 . 197 VAL C C 175.8 . .
825 . 197 VAL CB C 31.18 . .
826 . 198 LYS H H 8.07 . .
827 . 198 LYS N N 121.68 . .
828 . 198 LYS CA C 59.72 . .
829 . 198 LYS CB C 27.81 . .
830 . 199 PRO CA C 64.15 . .
831 . 199 PRO C C 179.2 . .
832 . 199 PRO CB C 29.31 . .
833 . 200 ILE H H 6.57 . .
834 . 200 ILE N N 118.73 . .
835 . 200 ILE CA C 63.99 . .
836 . 200 ILE C C 176.74 . .
837 . 200 ILE CB C 36.98 . .
838 . 201 GLU H H 7.94 . .
839 . 201 GLU N N 120.64 . .
840 . 201 GLU CA C 57.96 . .
841 . 201 GLU C C 178.49 . .
842 . 201 GLU CB C 27.81 . .
843 . 202 ASP H H 8.24 . .
844 . 202 ASP N N 119.28 . .
845 . 202 ASP CA C 56.24 . .
846 . 202 ASP C C 177.94 . .
847 . 202 ASP CB C 38.61 . .
848 . 203 ILE H H 7.28 . .
849 . 203 ILE N N 121.29 . .
850 . 203 ILE CA C 64.27 . .
851 . 203 ILE C C 178.8 . .
852 . 203 ILE CB C 37.01 . .
853 . 204 GLN H H 8.9 . .
854 . 204 GLN N N 122.03 . .
855 . 204 GLN CA C 58.83 . .
856 . 204 GLN C C 178.05 . .
857 . 204 GLN CB C 27.03 . .
858 . 205 ASP H H 8.69 . .
859 . 205 ASP N N 118.46 . .
860 . 205 ASP CA C 56.81 . .
861 . 205 ASP C C 177.08 . .
862 . 205 ASP CB C 39.98 . .
863 . 206 ASN H H 7.78 . .
864 . 206 ASN N N 118.82 . .
865 . 206 ASN CA C 56.91 . .
866 . 206 ASN C C 177.81 . .
867 . 206 ASN CB C 37.91 . .
868 . 207 LEU H H 8.33 . .
869 . 207 LEU N N 117.47 . .
870 . 207 LEU CA C 56.8 . .
871 . 207 LEU C C 178.23 . .
872 . 207 LEU CB C 41.27 . .
873 . 208 LEU H H 8.2 . .
874 . 208 LEU N N 120.34 . .
875 . 208 LEU CA C 56.51 . .
876 . 208 LEU C C 179.24 . .
877 . 208 LEU CB C 40.75 . .
878 . 209 GLN H H 7.62 . .
879 . 209 GLN N N 121.32 . .
880 . 209 GLN CA C 57.97 . .
881 . 209 GLN C C 178.46 . .
882 . 209 GLN CB C 27.81 . .
883 . 210 ALA H H 8.24 . .
884 . 210 ALA N N 122.88 . .
885 . 210 ALA CA C 53.95 . .
886 . 210 ALA C C 179.69 . .
887 . 210 ALA CB C 18.23 . .
888 . 211 LEU H H 8.92 . .
889 . 211 LEU N N 122.68 . .
890 . 211 LEU CA C 56.79 . .
891 . 211 LEU C C 176.27 . .
892 . 211 LEU CB C 39.98 . .
893 . 212 GLU H H 8.28 . .
894 . 212 GLU N N 121.38 . .
895 . 212 GLU CA C 59.39 . .
896 . 212 GLU C C 172.32 . .
897 . 212 GLU CB C 27.55 . .
898 . 213 LEU H H 7.23 . .
899 . 213 LEU N N 119.01 . .
900 . 213 LEU CA C 56.51 . .
901 . 213 LEU C C 179.41 . .
902 . 213 LEU CB C 39.98 . .
903 . 214 GLN H H 6.99 . .
904 . 214 GLN N N 118.51 . .
905 . 214 GLN CA C 55.38 . .
906 . 214 GLN C C 177.31 . .
907 . 214 GLN CB C 26 . .
908 . 215 LEU H H 8.08 . .
909 . 215 LEU N N 119.8 . .
910 . 215 LEU CA C 56.51 . .
911 . 215 LEU CB C 39.46 . .
912 . 216 LYS C C 178.33 . .
913 . 216 LYS CB C 30.92 . .
914 . 217 LEU H H 7.72 . .
915 . 217 LEU N N 117.12 . .
916 . 217 LEU CA C 55.36 . .
917 . 217 LEU C C 178.96 . .
918 . 217 LEU CB C 40.5 . .
919 . 218 ASN H H 8.25 . .
920 . 218 ASN N N 116.17 . .
921 . 218 ASN CA C 52.02 . .
922 . 218 ASN C C 176.82 . .
923 . 218 ASN CB C 39.46 . .
924 . 219 HIS H H 7.54 . .
925 . 219 HIS N N 115.06 . .
926 . 219 HIS CA C 51.05 . .
927 . 219 HIS CB C 28.33 . .
928 . 220 PRO CB C 30.55 . .
929 . 221 GLU CB C 26.92 . .
930 . 224 GLN CB C 26.72 . .
931 . 225 LEU CA C 56.79 . .
932 . 225 LEU C C 177.08 . .
933 . 225 LEU CB C 39.98 . .
934 . 226 PHE H H 8.45 . .
935 . 226 PHE N N 118.87 . .
936 . 226 PHE CA C 60.33 . .
937 . 226 PHE C C 175.46 . .
938 . 226 PHE CB C 37.13 . .
939 . 227 ALA H H 7.71 . .
940 . 227 ALA N N 120.26 . .
941 . 227 ALA CA C 53.95 . .
942 . 227 ALA C C 181.29 . .
943 . 227 ALA CB C 16.68 . .
944 . 228 LYS H H 7.9 . .
945 . 228 LYS N N 118.35 . .
946 . 228 LYS CA C 58.28 . .
947 . 228 LYS C C 179.46 . .
948 . 228 LYS CB C 31.18 . .
949 . 229 LEU H H 8.47 . .
950 . 229 LEU N N 122.56 . .
951 . 229 LEU CA C 56.51 . .
952 . 229 LEU C C 178.54 . .
953 . 229 LEU CB C 39.46 . .
954 . 230 LEU H H 7.82 . .
955 . 230 LEU N N 119.1 . .
956 . 230 LEU CA C 56.79 . .
957 . 230 LEU C C 181.34 . .
958 . 230 LEU CB C 38.68 . .
959 . 231 GLN H H 7.28 . .
960 . 231 GLN N N 118.93 . .
961 . 231 GLN CA C 57.1 . .
962 . 231 GLN C C 177.89 . .
963 . 231 GLN CB C 27.03 . .
964 . 232 LYS H H 7.71 . .
965 . 232 LYS N N 116.77 . .
966 . 232 LYS CA C 55.41 . .
967 . 232 LYS C C 178.31 . .
968 . 232 LYS CB C 29.62 . .
969 . 233 MET H H 7.7 . .
970 . 233 MET N N 117.74 . .
971 . 233 MET CA C 59.09 . .
972 . 233 MET C C 178.46 . .
973 . 233 MET CB C 31.43 . .
974 . 234 THR H H 7.31 . .
975 . 234 THR N N 116.28 . .
976 . 234 THR CA C 64.9 . .
977 . 234 THR C C 176.68 . .
978 . 234 THR CB C 67.18 . .
979 . 235 ASP H H 7.46 . .
980 . 235 ASP N N 124.41 . .
981 . 235 ASP CA C 56.24 . .
982 . 235 ASP C C 178.73 . .
983 . 235 ASP CB C 39.2 . .
984 . 236 LEU H H 7.95 . .
985 . 236 LEU N N 120.97 . .
986 . 236 LEU CA C 56.79 . .
987 . 236 LEU C C 177.97 . .
988 . 236 LEU CB C 41.79 . .
989 . 237 ARG H H 7.1 . .
990 . 237 ARG N N 117.61 . .
991 . 237 ARG CA C 57.65 . .
992 . 237 ARG C C 180.11 . .
993 . 237 ARG CB C 27.81 . .
994 . 238 GLN H H 7.35 . .
995 . 238 GLN N N 119.9 . .
996 . 238 GLN CA C 57.39 . .
997 . 238 GLN C C 177.73 . .
998 . 238 GLN CB C 26.26 . .
999 . 239 ILE H H 7.61 . .
1000 . 239 ILE N N 120.04 . .
1001 . 239 ILE CA C 62.05 . .
1002 . 239 ILE C C 179.35 . .
1003 . 239 ILE CB C 34.95 . .
1004 . 240 VAL H H 7.62 . .
1005 . 240 VAL N N 122.13 . .
1006 . 240 VAL CA C 66.53 . .
1007 . 240 VAL C C 177.52 . .
1008 . 240 VAL CB C 29.6 . .
1009 . 241 THR H H 8.13 . .
1010 . 241 THR N N 116.35 . .
1011 . 241 THR CA C 65.76 . .
1012 . 241 THR C C 175.98 . .
1013 . 241 THR CB C 67.1 . .
1014 . 242 GLU H H 8.19 . .
1015 . 242 GLU N N 121.73 . .
1016 . 242 GLU CA C 58.2 . .
1017 . 242 GLU C C 178.94 . .
1018 . 242 GLU CB C 28.33 . .
1019 . 243 HIS H H 8 . .
1020 . 243 HIS N N 124.01 . .
1021 . 243 HIS CA C 59.39 . .
1022 . 243 HIS C C 176.06 . .
1023 . 243 HIS CB C 29.88 . .
1024 . 244 VAL H H 8.43 . .
1025 . 244 VAL N N 119.64 . .
1026 . 244 VAL CA C 65.96 . .
1027 . 244 VAL C C 178.99 . .
1028 . 245 GLN H H 7.04 . .
1029 . 245 GLN N N 121.36 . .
1030 . 245 GLN CA C 57.39 . .
1031 . 245 GLN C C 178.7 . .
1032 . 245 GLN CB C 26.52 . .
1033 . 246 LEU H H 7.5 . .
1034 . 246 LEU N N 123.55 . .
1035 . 246 LEU CA C 56.51 . .
1036 . 246 LEU C C 178.86 . .
1037 . 246 LEU CB C 39.1 . .
1038 . 247 LEU H H 8.2 . .
1039 . 247 LEU N N 120.32 . .
1040 . 247 LEU CA C 56.51 . .
1041 . 247 LEU C C 176.76 . .
1042 . 247 LEU CB C 39.72 . .
1043 . 248 GLN H H 7.44 . .
1044 . 248 GLN N N 117.73 . .
1045 . 248 GLN CA C 57.1 . .
1046 . 248 GLN C C 179.33 . .
1047 . 248 GLN CB C 26.78 . .
1048 . 249 VAL H H 7.15 . .
1049 . 249 VAL N N 121.01 . .
1050 . 249 VAL CA C 65.1 . .
1051 . 249 VAL C C 179.43 . .
1052 . 249 VAL CB C 29.72 . .
1053 . 250 ILE H H 8.07 . .
1054 . 250 ILE N N 122.74 . .
1055 . 250 ILE CA C 64.85 . .
1056 . 250 ILE C C 177.03 . .
1057 . 250 ILE CB C 36.04 . .
1058 . 251 LYS H H 7.99 . .
1059 . 251 LYS N N 119.02 . .
1060 . 251 LYS CA C 57.42 . .
1061 . 251 LYS C C 177.5 . .
1062 . 251 LYS CB C 30.92 . .
1063 . 252 LYS H H 7.15 . .
1064 . 252 LYS N N 116.16 . .
1065 . 252 LYS CA C 56.84 . .
1066 . 252 LYS C C 177.65 . .
1067 . 252 LYS CB C 31.43 . .
1068 . 253 THR H H 7.35 . .
1069 . 253 THR N N 108.97 . .
1070 . 253 THR CA C 62.02 . .
1071 . 253 THR C C 174.66 . .
1072 . 253 THR CB C 69.13 . .
1073 . 254 GLU H H 8.02 . .
1074 . 254 GLU N N 123.44 . .
1075 . 254 GLU CA C 53.07 . .
1076 . 254 GLU C C 176.27 . .
1077 . 254 GLU CB C 27.03 . .
1078 . 255 THR H H 7.85 . .
1079 . 255 THR N N 115.89 . .
1080 . 255 THR CA C 59.53 . .
1081 . 255 THR C C 174.93 . .
1082 . 255 THR CB C 67.67 . .
1083 . 256 ASP H H 8.36 . .
1084 . 256 ASP N N 121.14 . .
1085 . 256 ASP CA C 52.79 . .
1086 . 256 ASP C C 174.96 . .
1087 . 256 ASP CB C 38.29 . .
1088 . 257 MET H H 7.5 . .
1089 . 257 MET N N 120.87 . .
1090 . 257 MET CA C 54.48 . .
1091 . 257 MET C C 180.14 . .
1092 . 257 MET CB C 31.98 . .
1093 . 258 SER H H 8.18 . .
1094 . 258 SER N N 120.5 . .
1095 . 258 SER CA C 56.14 . .
1096 . 258 SER C C 173.28 . .
1097 . 258 SER CB C 63.61 . .
1098 . 259 LEU H H 8.33 . .
1099 . 259 LEU N N 125.73 . .
1100 . 259 LEU CA C 51.9 . .
1101 . 259 LEU C C 176.27 . .
1102 . 259 LEU CB C 42.34 . .
1103 . 260 HIS H H 8.29 . .
1104 . 260 HIS N N 126.68 . .
1105 . 260 HIS CA C 55.08 . .
1106 . 260 HIS CB C 30.66 . .
1107 . 261 PRO CA C 64.64 . .
1108 . 261 PRO C C 179.03 . .
1109 . 261 PRO CB C 30.33 . .
1110 . 262 LEU H H 10.73 . .
1111 . 262 LEU N N 124.31 . .
1112 . 262 LEU CA C 57.08 . .
1113 . 262 LEU C C 180.01 . .
1114 . 262 LEU CB C 40.5 . .
1115 . 263 LEU H H 6.92 . .
1116 . 263 LEU N N 116.39 . .
1117 . 263 LEU CA C 55.36 . .
1118 . 263 LEU C C 176.06 . .
1119 . 263 LEU CB C 39.72 . .
1120 . 264 GLN H H 8.35 . .
1121 . 264 GLN N N 119.47 . .
1122 . 264 GLN CA C 58.25 . .
1123 . 264 GLN C C 177.88 . .
1124 . 264 GLN CB C 27.03 . .
1125 . 265 GLU H H 7.1 . .
1126 . 265 GLU N N 117.95 . .
1127 . 265 GLU CA C 57.67 . .
1128 . 265 GLU C C 179.04 . .
1129 . 265 GLU CB C 27.81 . .
1130 . 266 ILE H H 7.29 . .
1131 . 266 ILE N N 120.28 . .
1132 . 266 ILE CA C 64.56 . .
1133 . 266 ILE C C 175.78 . .
1134 . 266 ILE CB C 37.35 . .
1135 . 267 TYR H H 8.23 . .
1136 . 267 TYR N N 114.19 . .
1137 . 267 TYR CA C 59.4 . .
1138 . 267 TYR CB C 36.87 . .
1139 . 268 LYS H H 7.22 . .
1140 . 268 LYS N N 122.55 . .
1141 . 268 LYS CA C 57.64 . .
1142 . 268 LYS CB C 30.15 . .
stop_
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