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         <PDBx:title>Human Islet Amyloid Polypeptide Segment 19-SGNNFGAILSS-29 with Early Onset S20G Mutation Determined by MicroED</PDBx:title>
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         <PDBx:details xsi:nil="true" />
      </PDBx:pdbx_database_related>
      <PDBx:pdbx_database_related content_type="unspecified" db_id="5KO0" db_name="PDB">
         <PDBx:details xsi:nil="true" />
      </PDBx:pdbx_database_related>
   </PDBx:pdbx_database_relatedCategory>
   <PDBx:pdbx_database_statusCategory>
      <PDBx:pdbx_database_status entry_id="5KNZ">
         <PDBx:SG_entry>N</PDBx:SG_entry>
         <PDBx:date_begin_release_preparation xsi:nil="true" />
         <PDBx:deposit_site>RCSB</PDBx:deposit_site>
         <PDBx:pdb_format_compatible>Y</PDBx:pdb_format_compatible>
         <PDBx:process_site>RCSB</PDBx:process_site>
         <PDBx:status_code>REL</PDBx:status_code>
         <PDBx:status_code_sf>REL</PDBx:status_code_sf>
      </PDBx:pdbx_database_status>
   </PDBx:pdbx_database_statusCategory>
   <PDBx:pdbx_entity_nonpolyCategory>
      <PDBx:pdbx_entity_nonpoly entity_id="2">
         <PDBx:comp_id>HOH</PDBx:comp_id>
         <PDBx:name>water</PDBx:name>
      </PDBx:pdbx_entity_nonpoly>
   </PDBx:pdbx_entity_nonpolyCategory>
   <PDBx:pdbx_entity_src_synCategory>
      <PDBx:pdbx_entity_src_syn entity_id="1" pdbx_src_id="1">
         <PDBx:ncbi_taxonomy_id>9606</PDBx:ncbi_taxonomy_id>
         <PDBx:organism_common_name>Human</PDBx:organism_common_name>
         <PDBx:organism_scientific>Homo sapiens</PDBx:organism_scientific>
         <PDBx:pdbx_alt_source_flag>sample</PDBx:pdbx_alt_source_flag>
         <PDBx:pdbx_beg_seq_num>1</PDBx:pdbx_beg_seq_num>
         <PDBx:pdbx_end_seq_num>11</PDBx:pdbx_end_seq_num>
      </PDBx:pdbx_entity_src_syn>
   </PDBx:pdbx_entity_src_synCategory>
   <PDBx:pdbx_nonpoly_schemeCategory>
      <PDBx:pdbx_nonpoly_scheme asym_id="B" ndb_seq_num="1">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1</PDBx:auth_seq_num>
         <PDBx:entity_id>2</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>101</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
   </PDBx:pdbx_nonpoly_schemeCategory>
   <PDBx:pdbx_phasing_MRCategory>
      <PDBx:pdbx_phasing_MR entry_id="5KNZ">
         <PDBx:model_details>Phaser MODE: MR_AUTO</PDBx:model_details>
      </PDBx:pdbx_phasing_MR>
   </PDBx:pdbx_phasing_MRCategory>
   <PDBx:pdbx_poly_seq_schemeCategory>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="1">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>1</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>19</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="2">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>2</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>20</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="3">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>3</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>21</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="4">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>4</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>4</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>22</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="5">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>5</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>5</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>23</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="6">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>6</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>6</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>24</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="7">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>7</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>7</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>25</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="8">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>8</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>8</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>26</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="9">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>9</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>9</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>27</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="10">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>10</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>10</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>28</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="11">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>11</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>11</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>29</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
   </PDBx:pdbx_poly_seq_schemeCategory>
   <PDBx:pdbx_struct_assemblyCategory>
      <PDBx:pdbx_struct_assembly id="1">
         <PDBx:details>author_defined_assembly</PDBx:details>
         <PDBx:oligomeric_count>18</PDBx:oligomeric_count>
         <PDBx:oligomeric_details>octadecameric</PDBx:oligomeric_details>
      </PDBx:pdbx_struct_assembly>
   </PDBx:pdbx_struct_assemblyCategory>
   <PDBx:pdbx_struct_assembly_genCategory>
      <PDBx:pdbx_struct_assembly_gen assembly_id="1" asym_id_list="A,B" oper_expression="1"></PDBx:pdbx_struct_assembly_gen>
      <PDBx:pdbx_struct_assembly_gen assembly_id="1" asym_id_list="A,B" oper_expression="2"></PDBx:pdbx_struct_assembly_gen>
      <PDBx:pdbx_struct_assembly_gen assembly_id="1" asym_id_list="A,B" oper_expression="3"></PDBx:pdbx_struct_assembly_gen>
      <PDBx:pdbx_struct_assembly_gen assembly_id="1" asym_id_list="A,B" oper_expression="4"></PDBx:pdbx_struct_assembly_gen>
      <PDBx:pdbx_struct_assembly_gen assembly_id="1" asym_id_list="A,B" oper_expression="5"></PDBx:pdbx_struct_assembly_gen>
      <PDBx:pdbx_struct_assembly_gen assembly_id="1" asym_id_list="A,B" oper_expression="6"></PDBx:pdbx_struct_assembly_gen>
      <PDBx:pdbx_struct_assembly_gen assembly_id="1" asym_id_list="A,B" oper_expression="7"></PDBx:pdbx_struct_assembly_gen>
      <PDBx:pdbx_struct_assembly_gen assembly_id="1" asym_id_list="A,B" oper_expression="8"></PDBx:pdbx_struct_assembly_gen>
      <PDBx:pdbx_struct_assembly_gen assembly_id="1" asym_id_list="A,B" oper_expression="9"></PDBx:pdbx_struct_assembly_gen>
      <PDBx:pdbx_struct_assembly_gen assembly_id="1" asym_id_list="A,B" oper_expression="10"></PDBx:pdbx_struct_assembly_gen>
      <PDBx:pdbx_struct_assembly_gen assembly_id="1" asym_id_list="A,B" oper_expression="11"></PDBx:pdbx_struct_assembly_gen>
      <PDBx:pdbx_struct_assembly_gen assembly_id="1" asym_id_list="A,B" oper_expression="12"></PDBx:pdbx_struct_assembly_gen>
      <PDBx:pdbx_struct_assembly_gen assembly_id="1" asym_id_list="A,B" oper_expression="13"></PDBx:pdbx_struct_assembly_gen>
      <PDBx:pdbx_struct_assembly_gen assembly_id="1" asym_id_list="A,B" oper_expression="14"></PDBx:pdbx_struct_assembly_gen>
      <PDBx:pdbx_struct_assembly_gen assembly_id="1" asym_id_list="A,B" oper_expression="15"></PDBx:pdbx_struct_assembly_gen>
      <PDBx:pdbx_struct_assembly_gen assembly_id="1" asym_id_list="A,B" oper_expression="16"></PDBx:pdbx_struct_assembly_gen>
      <PDBx:pdbx_struct_assembly_gen assembly_id="1" asym_id_list="A,B" oper_expression="17"></PDBx:pdbx_struct_assembly_gen>
      <PDBx:pdbx_struct_assembly_gen assembly_id="1" asym_id_list="A,B" oper_expression="18"></PDBx:pdbx_struct_assembly_gen>
   </PDBx:pdbx_struct_assembly_genCategory>
   <PDBx:pdbx_struct_oper_listCategory>
      <PDBx:pdbx_struct_oper_list id="1">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>1.0000000000</PDBx:matrix33>
         <PDBx:name>1_555</PDBx:name>
         <PDBx:symmetry_operation>x,y,z</PDBx:symmetry_operation>
         <PDBx:type>identity operation</PDBx:type>
         <PDBx:vector1>0.0000000000</PDBx:vector1>
         <PDBx:vector2>0.0000000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="2">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>1.0000000000</PDBx:matrix33>
         <PDBx:name>1_155</PDBx:name>
         <PDBx:symmetry_operation>x-4,y,z</PDBx:symmetry_operation>
         <PDBx:type>crystal symmetry operation</PDBx:type>
         <PDBx:vector1>-19.1200000000</PDBx:vector1>
         <PDBx:vector2>0.0000000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="3">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>1.0000000000</PDBx:matrix33>
         <PDBx:name>1_255</PDBx:name>
         <PDBx:symmetry_operation>x-3,y,z</PDBx:symmetry_operation>
         <PDBx:type>crystal symmetry operation</PDBx:type>
         <PDBx:vector1>-14.3400000000</PDBx:vector1>
         <PDBx:vector2>0.0000000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="4">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>1.0000000000</PDBx:matrix33>
         <PDBx:name>1_355</PDBx:name>
         <PDBx:symmetry_operation>x-2,y,z</PDBx:symmetry_operation>
         <PDBx:type>crystal symmetry operation</PDBx:type>
         <PDBx:vector1>-9.5600000000</PDBx:vector1>
         <PDBx:vector2>0.0000000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="5">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>1.0000000000</PDBx:matrix33>
         <PDBx:name>1_455</PDBx:name>
         <PDBx:symmetry_operation>x-1,y,z</PDBx:symmetry_operation>
         <PDBx:type>crystal symmetry operation</PDBx:type>
         <PDBx:vector1>-4.7800000000</PDBx:vector1>
         <PDBx:vector2>0.0000000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="6">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>1.0000000000</PDBx:matrix33>
         <PDBx:name>1_655</PDBx:name>
         <PDBx:symmetry_operation>x+1,y,z</PDBx:symmetry_operation>
         <PDBx:type>crystal symmetry operation</PDBx:type>
         <PDBx:vector1>4.7800000000</PDBx:vector1>
         <PDBx:vector2>0.0000000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="7">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>1.0000000000</PDBx:matrix33>
         <PDBx:name>1_755</PDBx:name>
         <PDBx:symmetry_operation>x+2,y,z</PDBx:symmetry_operation>
         <PDBx:type>crystal symmetry operation</PDBx:type>
         <PDBx:vector1>9.5600000000</PDBx:vector1>
         <PDBx:vector2>0.0000000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="8">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>1.0000000000</PDBx:matrix33>
         <PDBx:name>1_855</PDBx:name>
         <PDBx:symmetry_operation>x+3,y,z</PDBx:symmetry_operation>
         <PDBx:type>crystal symmetry operation</PDBx:type>
         <PDBx:vector1>14.3400000000</PDBx:vector1>
         <PDBx:vector2>0.0000000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="9">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>1.0000000000</PDBx:matrix33>
         <PDBx:name>1_955</PDBx:name>
         <PDBx:symmetry_operation>x+4,y,z</PDBx:symmetry_operation>
         <PDBx:type>crystal symmetry operation</PDBx:type>
         <PDBx:vector1>19.1200000000</PDBx:vector1>
         <PDBx:vector2>0.0000000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="10">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>-1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>-1.0000000000</PDBx:matrix33>
         <PDBx:name>4_155</PDBx:name>
         <PDBx:symmetry_operation>x-7/2,-y+1/2,-z</PDBx:symmetry_operation>
         <PDBx:type>crystal symmetry operation</PDBx:type>
         <PDBx:vector1>-16.7300000000</PDBx:vector1>
         <PDBx:vector2>9.3000000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
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      <PDBx:pdbx_struct_oper_list id="11">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>-1.0000000000</PDBx:matrix22>
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         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>-1.0000000000</PDBx:matrix33>
         <PDBx:name>4_255</PDBx:name>
         <PDBx:symmetry_operation>x-5/2,-y+1/2,-z</PDBx:symmetry_operation>
         <PDBx:type>crystal symmetry operation</PDBx:type>
         <PDBx:vector1>-11.9500000000</PDBx:vector1>
         <PDBx:vector2>9.3000000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="12">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>-1.0000000000</PDBx:matrix22>
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         <PDBx:matrix33>-1.0000000000</PDBx:matrix33>
         <PDBx:name>4_355</PDBx:name>
         <PDBx:symmetry_operation>x-3/2,-y+1/2,-z</PDBx:symmetry_operation>
         <PDBx:type>crystal symmetry operation</PDBx:type>
         <PDBx:vector1>-7.1700000000</PDBx:vector1>
         <PDBx:vector2>9.3000000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="13">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>-1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>-1.0000000000</PDBx:matrix33>
         <PDBx:name>4_455</PDBx:name>
         <PDBx:symmetry_operation>x-1/2,-y+1/2,-z</PDBx:symmetry_operation>
         <PDBx:type>crystal symmetry operation</PDBx:type>
         <PDBx:vector1>-2.3900000000</PDBx:vector1>
         <PDBx:vector2>9.3000000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="14">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>-1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>-1.0000000000</PDBx:matrix33>
         <PDBx:name>4_555</PDBx:name>
         <PDBx:symmetry_operation>x+1/2,-y+1/2,-z</PDBx:symmetry_operation>
         <PDBx:type>crystal symmetry operation</PDBx:type>
         <PDBx:vector1>2.3900000000</PDBx:vector1>
         <PDBx:vector2>9.3000000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="15">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>-1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>-1.0000000000</PDBx:matrix33>
         <PDBx:name>4_655</PDBx:name>
         <PDBx:symmetry_operation>x+3/2,-y+1/2,-z</PDBx:symmetry_operation>
         <PDBx:type>crystal symmetry operation</PDBx:type>
         <PDBx:vector1>7.1700000000</PDBx:vector1>
         <PDBx:vector2>9.3000000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="16">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>-1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
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         <PDBx:matrix33>-1.0000000000</PDBx:matrix33>
         <PDBx:name>4_755</PDBx:name>
         <PDBx:symmetry_operation>x+5/2,-y+1/2,-z</PDBx:symmetry_operation>
         <PDBx:type>crystal symmetry operation</PDBx:type>
         <PDBx:vector1>11.9500000000</PDBx:vector1>
         <PDBx:vector2>9.3000000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="17">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>-1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
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         <PDBx:matrix33>-1.0000000000</PDBx:matrix33>
         <PDBx:name>4_855</PDBx:name>
         <PDBx:symmetry_operation>x+7/2,-y+1/2,-z</PDBx:symmetry_operation>
         <PDBx:type>crystal symmetry operation</PDBx:type>
         <PDBx:vector1>16.7300000000</PDBx:vector1>
         <PDBx:vector2>9.3000000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="18">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>-1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
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         <PDBx:matrix33>-1.0000000000</PDBx:matrix33>
         <PDBx:name>4_955</PDBx:name>
         <PDBx:symmetry_operation>x+9/2,-y+1/2,-z</PDBx:symmetry_operation>
         <PDBx:type>crystal symmetry operation</PDBx:type>
         <PDBx:vector1>21.5100000000</PDBx:vector1>
         <PDBx:vector2>9.3000000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
   </PDBx:pdbx_struct_oper_listCategory>
   <PDBx:pdbx_versionCategory>
      <PDBx:pdbx_version entry_id="5KNZ" major_version="4" minor_version="0000" revision_type="Initial release">
         <PDBx:details>Initial release</PDBx:details>
         <PDBx:revision_date>2016-12-21</PDBx:revision_date>
      </PDBx:pdbx_version>
   </PDBx:pdbx_versionCategory>
   <PDBx:phasingCategory>
      <PDBx:phasing method="MR"></PDBx:phasing>
   </PDBx:phasingCategory>
   <PDBx:refineCategory>
      <PDBx:refine entry_id="5KNZ" pdbx_refine_id="ELECTRON CRYSTALLOGRAPHY">
         <PDBx:B_iso_max>43.030</PDBx:B_iso_max>
         <PDBx:B_iso_mean>14.5116</PDBx:B_iso_mean>
         <PDBx:B_iso_min>0.790</PDBx:B_iso_min>
         <PDBx:ls_R_factor_R_free>0.2749</PDBx:ls_R_factor_R_free>
         <PDBx:ls_R_factor_R_work>0.2275</PDBx:ls_R_factor_R_work>
         <PDBx:ls_R_factor_obs>0.2318</PDBx:ls_R_factor_obs>
         <PDBx:ls_d_res_high>1.9020</PDBx:ls_d_res_high>
         <PDBx:ls_d_res_low>14.6080</PDBx:ls_d_res_low>
         <PDBx:ls_number_reflns_R_free>53</PDBx:ls_number_reflns_R_free>
         <PDBx:ls_number_reflns_obs>546</PDBx:ls_number_reflns_obs>
         <PDBx:ls_percent_reflns_R_free>9.7100</PDBx:ls_percent_reflns_R_free>
         <PDBx:ls_percent_reflns_obs>82.9800</PDBx:ls_percent_reflns_obs>
         <PDBx:overall_SU_ML>0.1300</PDBx:overall_SU_ML>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_ls_cross_valid_method>FREE R-VALUE</PDBx:pdbx_ls_cross_valid_method>
         <PDBx:pdbx_ls_sigma_F>1.490</PDBx:pdbx_ls_sigma_F>
         <PDBx:pdbx_method_to_determine_struct>MOLECULAR REPLACEMENT</PDBx:pdbx_method_to_determine_struct>
         <PDBx:pdbx_overall_phase_error>18.5700</PDBx:pdbx_overall_phase_error>
         <PDBx:pdbx_solvent_shrinkage_radii>0.9000</PDBx:pdbx_solvent_shrinkage_radii>
         <PDBx:pdbx_solvent_vdw_probe_radii>1.1100</PDBx:pdbx_solvent_vdw_probe_radii>
      </PDBx:refine>
   </PDBx:refineCategory>
   <PDBx:refine_histCategory>
      <PDBx:refine_hist cycle_id="final" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:d_res_high>1.9020</PDBx:d_res_high>
         <PDBx:d_res_low>14.6080</PDBx:d_res_low>
         <PDBx:number_atoms_solvent>1</PDBx:number_atoms_solvent>
         <PDBx:number_atoms_total>76</PDBx:number_atoms_total>
         <PDBx:pdbx_B_iso_mean_solvent>7.44</PDBx:pdbx_B_iso_mean_solvent>
         <PDBx:pdbx_number_atoms_ligand>0</PDBx:pdbx_number_atoms_ligand>
         <PDBx:pdbx_number_atoms_nucleic_acid>0</PDBx:pdbx_number_atoms_nucleic_acid>
         <PDBx:pdbx_number_atoms_protein>75</PDBx:pdbx_number_atoms_protein>
         <PDBx:pdbx_number_residues_total>11</PDBx:pdbx_number_residues_total>
      </PDBx:refine_hist>
   </PDBx:refine_histCategory>
   <PDBx:refine_ls_restrCategory>
      <PDBx:refine_ls_restr pdbx_refine_id="ELECTRON CRYSTALLOGRAPHY" type="f_bond_d">
         <PDBx:dev_ideal>0.010</PDBx:dev_ideal>
         <PDBx:number>75</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="ELECTRON CRYSTALLOGRAPHY" type="f_angle_d">
         <PDBx:dev_ideal>1.233</PDBx:dev_ideal>
         <PDBx:number>100</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="ELECTRON CRYSTALLOGRAPHY" type="f_chiral_restr">
         <PDBx:dev_ideal>0.037</PDBx:dev_ideal>
         <PDBx:number>11</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="ELECTRON CRYSTALLOGRAPHY" type="f_plane_restr">
         <PDBx:dev_ideal>0.004</PDBx:dev_ideal>
         <PDBx:number>14</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="ELECTRON CRYSTALLOGRAPHY" type="f_dihedral_angle_d">
         <PDBx:dev_ideal>10.079</PDBx:dev_ideal>
         <PDBx:number>24</PDBx:number>
      </PDBx:refine_ls_restr>
   </PDBx:refine_ls_restrCategory>
   <PDBx:refine_ls_shellCategory>
      <PDBx:refine_ls_shell d_res_high="1.9016" pdbx_refine_id="ELECTRON CRYSTALLOGRAPHY">
         <PDBx:R_factor_R_free>0.2749</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_work>0.2275</PDBx:R_factor_R_work>
         <PDBx:d_res_low>14.6087</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>53</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>493</PDBx:number_reflns_R_work>
         <PDBx:number_reflns_all>546</PDBx:number_reflns_all>
         <PDBx:pdbx_total_number_of_bins_used>1</PDBx:pdbx_total_number_of_bins_used>
         <PDBx:percent_reflns_obs>83.0000</PDBx:percent_reflns_obs>
      </PDBx:refine_ls_shell>
   </PDBx:refine_ls_shellCategory>
   <PDBx:reflnsCategory>
      <PDBx:reflns pdbx_ordinal="1">
         <PDBx:B_iso_Wilson_estimate>15.550</PDBx:B_iso_Wilson_estimate>
         <PDBx:d_resolution_high>1.900</PDBx:d_resolution_high>
         <PDBx:d_resolution_low>35.400</PDBx:d_resolution_low>
         <PDBx:entry_id>5KNZ</PDBx:entry_id>
         <PDBx:number_obs>548</PDBx:number_obs>
         <PDBx:observed_criterion_sigma_I>-3.000</PDBx:observed_criterion_sigma_I>
         <PDBx:pdbx_CC_half>0.989</PDBx:pdbx_CC_half>
         <PDBx:pdbx_Rmerge_I_obs>0.106</PDBx:pdbx_Rmerge_I_obs>
         <PDBx:pdbx_Rrim_I_all>0.130</PDBx:pdbx_Rrim_I_all>
         <PDBx:pdbx_chi_squared>0.931</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_netI_over_sigmaI>5.650</PDBx:pdbx_netI_over_sigmaI>
         <PDBx:pdbx_number_measured_all>1380</PDBx:pdbx_number_measured_all>
         <PDBx:percent_possible_obs>82.900</PDBx:percent_possible_obs>
      </PDBx:reflns>
   </PDBx:reflnsCategory>
   <PDBx:reflns_shellCategory>
      <PDBx:reflns_shell pdbx_ordinal="1">
         <PDBx:Rmerge_I_obs>0.150</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>1.900</PDBx:d_res_high>
         <PDBx:d_res_low>2.130</PDBx:d_res_low>
         <PDBx:meanI_over_sigI_obs>3.650</PDBx:meanI_over_sigI_obs>
         <PDBx:number_measured_obs>221</PDBx:number_measured_obs>
         <PDBx:number_possible>178</PDBx:number_possible>
         <PDBx:number_unique_obs>115</PDBx:number_unique_obs>
         <PDBx:pdbx_CC_half>0.939</PDBx:pdbx_CC_half>
         <PDBx:pdbx_Rrim_I_all>0.191</PDBx:pdbx_Rrim_I_all>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>64.600</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="2">
         <PDBx:Rmerge_I_obs>0.171</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>2.130</PDBx:d_res_high>
         <PDBx:d_res_low>2.450</PDBx:d_res_low>
         <PDBx:meanI_over_sigI_obs>4.770</PDBx:meanI_over_sigI_obs>
         <PDBx:number_measured_obs>382</PDBx:number_measured_obs>
         <PDBx:number_possible>171</PDBx:number_possible>
         <PDBx:number_unique_obs>153</PDBx:number_unique_obs>
         <PDBx:pdbx_CC_half>0.978</PDBx:pdbx_CC_half>
         <PDBx:pdbx_Rrim_I_all>0.211</PDBx:pdbx_Rrim_I_all>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>89.500</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="3">
         <PDBx:Rmerge_I_obs>0.146</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>2.450</PDBx:d_res_high>
         <PDBx:d_res_low>3.010</PDBx:d_res_low>
         <PDBx:meanI_over_sigI_obs>5.580</PDBx:meanI_over_sigI_obs>
         <PDBx:number_measured_obs>316</PDBx:number_measured_obs>
         <PDBx:number_possible>119</PDBx:number_possible>
         <PDBx:number_unique_obs>111</PDBx:number_unique_obs>
         <PDBx:pdbx_CC_half>0.963</PDBx:pdbx_CC_half>
         <PDBx:pdbx_Rrim_I_all>0.182</PDBx:pdbx_Rrim_I_all>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>93.300</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="4">
         <PDBx:Rmerge_I_obs>0.114</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>3.010</PDBx:d_res_high>
         <PDBx:d_res_low>4.250</PDBx:d_res_low>
         <PDBx:meanI_over_sigI_obs>7.840</PDBx:meanI_over_sigI_obs>
         <PDBx:number_measured_obs>306</PDBx:number_measured_obs>
         <PDBx:number_possible>121</PDBx:number_possible>
         <PDBx:number_unique_obs>110</PDBx:number_unique_obs>
         <PDBx:pdbx_CC_half>0.977</PDBx:pdbx_CC_half>
         <PDBx:pdbx_Rrim_I_all>0.138</PDBx:pdbx_Rrim_I_all>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>90.900</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="5">
         <PDBx:Rmerge_I_obs>0.061</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>4.250</PDBx:d_res_high>
         <PDBx:d_res_low>35.400</PDBx:d_res_low>
         <PDBx:meanI_over_sigI_obs>7.920</PDBx:meanI_over_sigI_obs>
         <PDBx:number_measured_obs>155</PDBx:number_measured_obs>
         <PDBx:number_possible>72</PDBx:number_possible>
         <PDBx:number_unique_obs>59</PDBx:number_unique_obs>
         <PDBx:pdbx_CC_half>0.996</PDBx:pdbx_CC_half>
         <PDBx:pdbx_Rrim_I_all>0.073</PDBx:pdbx_Rrim_I_all>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>81.900</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
   </PDBx:reflns_shellCategory>
   <PDBx:softwareCategory>
      <PDBx:software pdbx_ordinal="1">
         <PDBx:classification>data scaling</PDBx:classification>
         <PDBx:contact_author>Wolfgang Kabsch</PDBx:contact_author>
         <PDBx:location>http://www.mpimf-heidelberg.mpg.de/~kabsch/xds/html_doc/xscale_program.html</PDBx:location>
         <PDBx:name>XSCALE</PDBx:name>
         <PDBx:type>package</PDBx:type>
         <PDBx:version xsi:nil="true" />
      </PDBx:software>
      <PDBx:software pdbx_ordinal="2">
         <PDBx:classification>molecular replacement</PDBx:classification>
         <PDBx:contact_author>Randy J. Read</PDBx:contact_author>
         <PDBx:contact_author_email>cimr-phaser@lists.cam.ac.uk</PDBx:contact_author_email>
         <PDBx:date>Tue May 20 11:52:06 2014</PDBx:date>
         <PDBx:location>http://www-structmed.cimr.cam.ac.uk/phaser/</PDBx:location>
         <PDBx:name>PHASER</PDBx:name>
         <PDBx:type>program</PDBx:type>
         <PDBx:version>2.5.6</PDBx:version>
      </PDBx:software>
      <PDBx:software pdbx_ordinal="3">
         <PDBx:classification>refinement</PDBx:classification>
         <PDBx:contact_author>Paul D. Adams</PDBx:contact_author>
         <PDBx:contact_author_email>PDAdams@lbl.gov</PDBx:contact_author_email>
         <PDBx:language>C++</PDBx:language>
         <PDBx:location>http://www.phenix-online.org/</PDBx:location>
         <PDBx:name>PHENIX</PDBx:name>
         <PDBx:type>package</PDBx:type>
         <PDBx:version xsi:nil="true" />
      </PDBx:software>
      <PDBx:software pdbx_ordinal="4">
         <PDBx:classification>data extraction</PDBx:classification>
         <PDBx:contact_author>PDB</PDBx:contact_author>
         <PDBx:contact_author_email>deposit@deposit.rcsb.org</PDBx:contact_author_email>
         <PDBx:date>June. 20, 2015</PDBx:date>
         <PDBx:language>C++</PDBx:language>
         <PDBx:location>http://sw-tools.pdb.org/apps/PDB_EXTRACT/</PDBx:location>
         <PDBx:name>PDB_EXTRACT</PDBx:name>
         <PDBx:type>package</PDBx:type>
         <PDBx:version>3.20</PDBx:version>
      </PDBx:software>
   </PDBx:softwareCategory>
   <PDBx:structCategory>
      <PDBx:struct entry_id="5KNZ">
         <PDBx:pdbx_CASP_flag>N</PDBx:pdbx_CASP_flag>
         <PDBx:pdbx_descriptor>Islet amyloid polypeptide</PDBx:pdbx_descriptor>
         <PDBx:title>Human Islet Amyloid Polypeptide Segment 19-SGNNFGAILSS-29 with Early Onset S20G Mutation Determined by MicroED</PDBx:title>
      </PDBx:struct>
   </PDBx:structCategory>
   <PDBx:struct_asymCategory>
      <PDBx:struct_asym id="A">
         <PDBx:entity_id>1</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="B">
         <PDBx:entity_id>2</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
   </PDBx:struct_asymCategory>
   <PDBx:struct_biolCategory>
      <PDBx:struct_biol id="1">
         <PDBx:details>The biological unit is an extended pair of beta sheets comprising peptides at positions X,Y,Z and 1/2+X,-1/2-Y,-Z repeated ad infinitum along the a crystal axis.</PDBx:details>
      </PDBx:struct_biol>
   </PDBx:struct_biolCategory>
   <PDBx:struct_keywordsCategory>
      <PDBx:struct_keywords entry_id="5KNZ">
         <PDBx:pdbx_keywords>PROTEIN FIBRIL</PDBx:pdbx_keywords>
         <PDBx:text>Amyloid, islet amyloid polypeptide, Type II Diabetes, Toxic Spine, MicroED, PROTEIN FIBRIL</PDBx:text>
      </PDBx:struct_keywords>
   </PDBx:struct_keywordsCategory>
   <PDBx:struct_refCategory>
      <PDBx:struct_ref id="1">
         <PDBx:db_code>IAPP_HUMAN</PDBx:db_code>
         <PDBx:db_name>UNP</PDBx:db_name>
         <PDBx:entity_id>1</PDBx:entity_id>
         <PDBx:pdbx_align_begin>52</PDBx:pdbx_align_begin>
         <PDBx:pdbx_db_accession>P10997</PDBx:pdbx_db_accession>
         <PDBx:pdbx_seq_one_letter_code>SSNNFGAILSS</PDBx:pdbx_seq_one_letter_code>
      </PDBx:struct_ref>
   </PDBx:struct_refCategory>
   <PDBx:struct_ref_seqCategory>
      <PDBx:struct_ref_seq align_id="1">
         <PDBx:db_align_beg>52</PDBx:db_align_beg>
         <PDBx:db_align_end>62</PDBx:db_align_end>
         <PDBx:pdbx_PDB_id_code>5KNZ</PDBx:pdbx_PDB_id_code>
         <PDBx:pdbx_auth_seq_align_beg>19</PDBx:pdbx_auth_seq_align_beg>
         <PDBx:pdbx_auth_seq_align_end>29</PDBx:pdbx_auth_seq_align_end>
         <PDBx:pdbx_db_accession>P10997</PDBx:pdbx_db_accession>
         <PDBx:pdbx_strand_id>A</PDBx:pdbx_strand_id>
         <PDBx:ref_id>1</PDBx:ref_id>
         <PDBx:seq_align_beg>1</PDBx:seq_align_beg>
         <PDBx:seq_align_end>11</PDBx:seq_align_end>
      </PDBx:struct_ref_seq>
   </PDBx:struct_ref_seqCategory>
   <PDBx:struct_ref_seq_difCategory>
      <PDBx:struct_ref_seq_dif pdbx_ordinal="1">
         <PDBx:align_id>1</PDBx:align_id>
         <PDBx:db_mon_id>SER</PDBx:db_mon_id>
         <PDBx:details>engineered mutation</PDBx:details>
         <PDBx:mon_id>GLY</PDBx:mon_id>
         <PDBx:pdbx_auth_seq_num>20</PDBx:pdbx_auth_seq_num>
         <PDBx:pdbx_pdb_id_code>5KNZ</PDBx:pdbx_pdb_id_code>
         <PDBx:pdbx_pdb_strand_id>A</PDBx:pdbx_pdb_strand_id>
         <PDBx:pdbx_seq_db_accession_code>P10997</PDBx:pdbx_seq_db_accession_code>
         <PDBx:pdbx_seq_db_name>UNP</PDBx:pdbx_seq_db_name>
         <PDBx:pdbx_seq_db_seq_num>53</PDBx:pdbx_seq_db_seq_num>
         <PDBx:seq_num>2</PDBx:seq_num>
      </PDBx:struct_ref_seq_dif>
   </PDBx:struct_ref_seq_difCategory>
   <PDBx:symmetryCategory>
      <PDBx:symmetry entry_id="5KNZ">
         <PDBx:Int_Tables_number>19</PDBx:Int_Tables_number>
         <PDBx:space_group_name_H-M>P 21 21 21</PDBx:space_group_name_H-M>
      </PDBx:symmetry>
   </PDBx:symmetryCategory>
</PDBx:datablock>
