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         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="32">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="33">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="34">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="35">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="36">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="37">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="38">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="39">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="40">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="41">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="42">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="43">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="44">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="45">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="46">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="47">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="48">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="49">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="50">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="51">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="52">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="53">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="54">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="55">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="56">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="57">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="58">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="59">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="60">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="61">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="62">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="63">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="64">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="65">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="66">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="67">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="68">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="69">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="70">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="71">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="72">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="73">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="74">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="75">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="76">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="77">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="78">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="79">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="80">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="81">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="82">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="83">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="84">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="85">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="86">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="87">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="88">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="89">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="90">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
   </PDBx:entity_poly_seqCategory>
   <PDBx:entity_src_genCategory>
      <PDBx:entity_src_gen entity_id="1">
         <PDBx:gene_src_common_name>Baker&apos;s yeast</PDBx:gene_src_common_name>
         <PDBx:gene_src_strain>ATCC 204508 / S288c</PDBx:gene_src_strain>
         <PDBx:pdbx_gene_src_gene>RNT1, YM9408.01C, YM9959.21, YMR239C</PDBx:pdbx_gene_src_gene>
         <PDBx:pdbx_gene_src_ncbi_taxonomy_id>559292</PDBx:pdbx_gene_src_ncbi_taxonomy_id>
         <PDBx:pdbx_gene_src_scientific_name>Saccharomyces cerevisiae</PDBx:pdbx_gene_src_scientific_name>
         <PDBx:pdbx_gene_src_variant>YMR239C</PDBx:pdbx_gene_src_variant>
         <PDBx:pdbx_host_org_ncbi_taxonomy_id>511693</PDBx:pdbx_host_org_ncbi_taxonomy_id>
         <PDBx:pdbx_host_org_scientific_name>Escherichia coli</PDBx:pdbx_host_org_scientific_name>
         <PDBx:pdbx_host_org_strain>BL21</PDBx:pdbx_host_org_strain>
         <PDBx:pdbx_host_org_vector_type>plasmid</PDBx:pdbx_host_org_vector_type>
         <PDBx:plasmid_name>PGEX-2T</PDBx:plasmid_name>
      </PDBx:entity_src_gen>
   </PDBx:entity_src_genCategory>
   <PDBx:entryCategory>
      <PDBx:entry id="2LUQ"></PDBx:entry>
   </PDBx:entryCategory>
   <PDBx:exptlCategory>
      <PDBx:exptl entry_id="2LUQ" method="SOLUTION NMR">
      </PDBx:exptl>
   </PDBx:exptlCategory>
   <PDBx:pdbx_database_relatedCategory>
      <PDBx:pdbx_database_related content_type="unspecified" db_id="18535" db_name="BMRB">
         <PDBx:details xsi:nil="true" />
      </PDBx:pdbx_database_related>
      <PDBx:pdbx_database_related content_type="unspecified" db_id="2LUP" db_name="PDB">
         <PDBx:details xsi:nil="true" />
      </PDBx:pdbx_database_related>
   </PDBx:pdbx_database_relatedCategory>
   <PDBx:pdbx_database_statusCategory>
      <PDBx:pdbx_database_status entry_id="2LUQ">
         <PDBx:deposit_site>BMRB</PDBx:deposit_site>
         <PDBx:process_site>RCSB</PDBx:process_site>
         <PDBx:status_code>REL</PDBx:status_code>
         <PDBx:status_code_cs>REL</PDBx:status_code_cs>
         <PDBx:status_code_mr>REL</PDBx:status_code_mr>
      </PDBx:pdbx_database_status>
   </PDBx:pdbx_database_statusCategory>
   <PDBx:pdbx_nmr_constraintsCategory>
      <PDBx:pdbx_nmr_constraints entry_id="2LUQ">
         <PDBx:NOE_constraints_total>1859</PDBx:NOE_constraints_total>
         <PDBx:NOE_intraresidue_total_count>585</PDBx:NOE_intraresidue_total_count>
         <PDBx:NOE_long_range_total_count>410</PDBx:NOE_long_range_total_count>
         <PDBx:NOE_medium_range_total_count>420</PDBx:NOE_medium_range_total_count>
         <PDBx:NOE_sequential_total_count>444</PDBx:NOE_sequential_total_count>
      </PDBx:pdbx_nmr_constraints>
   </PDBx:pdbx_nmr_constraintsCategory>
   <PDBx:pdbx_nmr_ensembleCategory>
      <PDBx:pdbx_nmr_ensemble entry_id="2LUQ">
         <PDBx:conformer_selection_criteria>structures with the lowest energy</PDBx:conformer_selection_criteria>
         <PDBx:conformers_calculated_total_number>100</PDBx:conformers_calculated_total_number>
         <PDBx:conformers_submitted_total_number>20</PDBx:conformers_submitted_total_number>
      </PDBx:pdbx_nmr_ensemble>
   </PDBx:pdbx_nmr_ensembleCategory>
   <PDBx:pdbx_nmr_exptlCategory>
      <PDBx:pdbx_nmr_exptl conditions_id="1" experiment_id="1" solution_id="1">
         <PDBx:type>2D 1H-15N HSQC</PDBx:type>
      </PDBx:pdbx_nmr_exptl>
      <PDBx:pdbx_nmr_exptl conditions_id="1" experiment_id="2" solution_id="1">
         <PDBx:type>3D HNCACB</PDBx:type>
      </PDBx:pdbx_nmr_exptl>
      <PDBx:pdbx_nmr_exptl conditions_id="1" experiment_id="3" solution_id="1">
         <PDBx:type>3D CBCA(CO)NH</PDBx:type>
      </PDBx:pdbx_nmr_exptl>
      <PDBx:pdbx_nmr_exptl conditions_id="1" experiment_id="4" solution_id="1">
         <PDBx:type>3D HNCO</PDBx:type>
      </PDBx:pdbx_nmr_exptl>
      <PDBx:pdbx_nmr_exptl conditions_id="1" experiment_id="5" solution_id="2">
         <PDBx:type>3D HCCH-TOCSY</PDBx:type>
      </PDBx:pdbx_nmr_exptl>
      <PDBx:pdbx_nmr_exptl conditions_id="1" experiment_id="6" solution_id="2">
         <PDBx:type>3D HCCH-COSY</PDBx:type>
      </PDBx:pdbx_nmr_exptl>
      <PDBx:pdbx_nmr_exptl conditions_id="1" experiment_id="7" solution_id="1">
         <PDBx:type>3D 1H-15N NOESY</PDBx:type>
      </PDBx:pdbx_nmr_exptl>
      <PDBx:pdbx_nmr_exptl conditions_id="1" experiment_id="8" solution_id="2">
         <PDBx:type>3D 1H-13C NOESY aliphatic</PDBx:type>
      </PDBx:pdbx_nmr_exptl>
   </PDBx:pdbx_nmr_exptlCategory>
   <PDBx:pdbx_nmr_exptl_sampleCategory>
      <PDBx:pdbx_nmr_exptl_sample component="entity-1" solution_id="1">
         <PDBx:concentration>1</PDBx:concentration>
         <PDBx:concentration_units>mM</PDBx:concentration_units>
         <PDBx:isotopic_labeling>[U-100&#37; 13C; U-100&#37; 15N]</PDBx:isotopic_labeling>
      </PDBx:pdbx_nmr_exptl_sample>
      <PDBx:pdbx_nmr_exptl_sample component="H2O-2" solution_id="1">
         <PDBx:concentration>90</PDBx:concentration>
         <PDBx:concentration_units>&#37;</PDBx:concentration_units>
      </PDBx:pdbx_nmr_exptl_sample>
      <PDBx:pdbx_nmr_exptl_sample component="D2O-3" solution_id="1">
         <PDBx:concentration>10</PDBx:concentration>
         <PDBx:concentration_units>&#37;</PDBx:concentration_units>
         <PDBx:isotopic_labeling>[U-100&#37; 2H]</PDBx:isotopic_labeling>
      </PDBx:pdbx_nmr_exptl_sample>
      <PDBx:pdbx_nmr_exptl_sample component="sodium chloride-4" solution_id="1">
         <PDBx:concentration>150</PDBx:concentration>
         <PDBx:concentration_units>mM</PDBx:concentration_units>
      </PDBx:pdbx_nmr_exptl_sample>
      <PDBx:pdbx_nmr_exptl_sample component="sodium phosphate-5" solution_id="1">
         <PDBx:concentration>20</PDBx:concentration>
         <PDBx:concentration_units>mM</PDBx:concentration_units>
      </PDBx:pdbx_nmr_exptl_sample>
      <PDBx:pdbx_nmr_exptl_sample component="entity-6" solution_id="2">
         <PDBx:concentration>1</PDBx:concentration>
         <PDBx:concentration_units>mM</PDBx:concentration_units>
         <PDBx:isotopic_labeling>[U-100&#37; 13C; U-100&#37; 15N]</PDBx:isotopic_labeling>
      </PDBx:pdbx_nmr_exptl_sample>
      <PDBx:pdbx_nmr_exptl_sample component="D2O-7" solution_id="2">
         <PDBx:concentration>100</PDBx:concentration>
         <PDBx:concentration_units>&#37;</PDBx:concentration_units>
         <PDBx:isotopic_labeling>[U-100&#37; 2H]</PDBx:isotopic_labeling>
      </PDBx:pdbx_nmr_exptl_sample>
      <PDBx:pdbx_nmr_exptl_sample component="sodium chloride-8" solution_id="2">
         <PDBx:concentration>150</PDBx:concentration>
         <PDBx:concentration_units>&#37;</PDBx:concentration_units>
      </PDBx:pdbx_nmr_exptl_sample>
      <PDBx:pdbx_nmr_exptl_sample component="sodium phosphate-9" solution_id="2">
         <PDBx:concentration>20</PDBx:concentration>
         <PDBx:concentration_units>mM</PDBx:concentration_units>
      </PDBx:pdbx_nmr_exptl_sample>
   </PDBx:pdbx_nmr_exptl_sampleCategory>
   <PDBx:pdbx_nmr_exptl_sample_conditionsCategory>
      <PDBx:pdbx_nmr_exptl_sample_conditions conditions_id="1">
         <PDBx:ionic_strength>150</PDBx:ionic_strength>
         <PDBx:pH>6.5</PDBx:pH>
         <PDBx:pressure>ambient</PDBx:pressure>
         <PDBx:temperature>298</PDBx:temperature>
      </PDBx:pdbx_nmr_exptl_sample_conditions>
   </PDBx:pdbx_nmr_exptl_sample_conditionsCategory>
   <PDBx:pdbx_nmr_refineCategory>
      <PDBx:pdbx_nmr_refine entry_id="2LUQ">
         <PDBx:method>simulated annealing</PDBx:method>
      </PDBx:pdbx_nmr_refine>
   </PDBx:pdbx_nmr_refineCategory>
   <PDBx:pdbx_nmr_representativeCategory>
      <PDBx:pdbx_nmr_representative entry_id="2LUQ">
         <PDBx:conformer_id>1</PDBx:conformer_id>
         <PDBx:selection_criteria>lowest energy</PDBx:selection_criteria>
      </PDBx:pdbx_nmr_representative>
   </PDBx:pdbx_nmr_representativeCategory>
   <PDBx:pdbx_nmr_sample_detailsCategory>
      <PDBx:pdbx_nmr_sample_details solution_id="1">
         <PDBx:contents>1 mM [U-100&#37; 13C; U-100&#37; 15N] protein, 90 &#37; H2O, 10 &#37; [U-100&#37; 2H] D2O, 150 mM sodium chloride, 20 mM sodium phosphate, 90&#37; H2O/10&#37; D2O</PDBx:contents>
         <PDBx:solvent_system>90&#37; H2O/10&#37; D2O</PDBx:solvent_system>
      </PDBx:pdbx_nmr_sample_details>
      <PDBx:pdbx_nmr_sample_details solution_id="2">
         <PDBx:contents>1 mM [U-100&#37; 13C; U-100&#37; 15N] protein, 100 &#37; [U-100&#37; 2H] D2O, 150 &#37; sodium chloride, 20 mM sodium phosphate, 100&#37; D2O</PDBx:contents>
         <PDBx:solvent_system>100&#37; D2O</PDBx:solvent_system>
      </PDBx:pdbx_nmr_sample_details>
   </PDBx:pdbx_nmr_sample_detailsCategory>
   <PDBx:pdbx_nmr_softwareCategory>
      <PDBx:pdbx_nmr_software ordinal="1">
         <PDBx:authors>Bruker Biospin</PDBx:authors>
         <PDBx:classification>collection</PDBx:classification>
         <PDBx:name>TOPSPIN</PDBx:name>
         <PDBx:version>2.0</PDBx:version>
      </PDBx:pdbx_nmr_software>
      <PDBx:pdbx_nmr_software ordinal="2">
         <PDBx:authors>Delaglio, Grzesiek, Vuister, Zhu, Pfeifer and Bax</PDBx:authors>
         <PDBx:classification>processing</PDBx:classification>
         <PDBx:name>NMRPipe</PDBx:name>
      </PDBx:pdbx_nmr_software>
      <PDBx:pdbx_nmr_software ordinal="3">
         <PDBx:authors>Johnson, One Moon Scientific</PDBx:authors>
         <PDBx:classification>chemical shift assignment</PDBx:classification>
         <PDBx:name>NMRView</PDBx:name>
      </PDBx:pdbx_nmr_software>
      <PDBx:pdbx_nmr_software ordinal="4">
         <PDBx:authors>Cornilescu, Delaglio and Bax</PDBx:authors>
         <PDBx:classification>data analysis</PDBx:classification>
         <PDBx:name>TALOS</PDBx:name>
      </PDBx:pdbx_nmr_software>
      <PDBx:pdbx_nmr_software ordinal="5">
         <PDBx:authors>Schwieters, Kuszewski, Tjandra and Clore</PDBx:authors>
         <PDBx:classification>structure solution</PDBx:classification>
         <PDBx:name>X-PLOR_NIH</PDBx:name>
      </PDBx:pdbx_nmr_software>
      <PDBx:pdbx_nmr_software ordinal="6">
         <PDBx:authors>Schwieters, Kuszewski, Tjandra and Clore</PDBx:authors>
         <PDBx:classification>refinement</PDBx:classification>
         <PDBx:name>X-PLOR_NIH</PDBx:name>
      </PDBx:pdbx_nmr_software>
   </PDBx:pdbx_nmr_softwareCategory>
   <PDBx:pdbx_nmr_spectrometerCategory>
      <PDBx:pdbx_nmr_spectrometer spectrometer_id="1">
         <PDBx:field_strength>500</PDBx:field_strength>
         <PDBx:manufacturer>Bruker</PDBx:manufacturer>
         <PDBx:model>DRX</PDBx:model>
         <PDBx:type>Bruker DRX</PDBx:type>
      </PDBx:pdbx_nmr_spectrometer>
      <PDBx:pdbx_nmr_spectrometer spectrometer_id="2">
         <PDBx:field_strength>600</PDBx:field_strength>
         <PDBx:manufacturer>Bruker</PDBx:manufacturer>
         <PDBx:model>DRX</PDBx:model>
         <PDBx:type>Bruker DRX</PDBx:type>
      </PDBx:pdbx_nmr_spectrometer>
   </PDBx:pdbx_nmr_spectrometerCategory>
   <PDBx:pdbx_poly_seq_schemeCategory>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="1">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>364</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>1</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>364</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="2">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>365</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>2</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>365</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="3">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>366</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>3</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>366</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="4">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>367</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>4</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>367</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="5">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>368</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>5</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>368</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="6">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>369</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>6</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>369</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="7">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>370</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>7</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>370</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="8">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>371</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>8</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>371</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="9">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>372</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>9</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>372</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="10">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>373</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>10</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>373</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="11">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>374</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>11</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>374</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="12">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>375</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>12</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>375</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="13">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>376</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>13</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>376</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="14">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>377</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>14</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>377</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="15">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>378</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>15</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>378</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="16">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>379</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>16</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>379</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="17">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>380</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>17</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>380</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="18">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>381</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>18</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>381</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="19">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>382</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>19</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>382</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="20">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>383</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>20</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>383</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="21">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>384</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>21</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>384</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="22">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>385</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>22</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>385</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="23">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>386</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>23</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>386</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="24">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>387</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>24</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>387</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="25">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>388</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>25</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>388</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="26">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>389</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>26</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>389</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="27">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>390</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>27</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>390</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="28">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>391</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>28</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>391</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="29">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>392</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>29</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>392</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="30">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>393</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>30</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>393</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="31">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>394</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>31</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>394</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="32">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>395</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>32</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>395</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="33">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>396</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>33</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>396</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="34">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>397</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>34</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>397</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="35">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>398</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>35</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>398</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="36">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>399</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>36</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>399</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="37">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>400</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>37</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>400</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="38">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>401</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>38</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>401</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="39">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>402</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>39</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>402</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="40">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>403</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>40</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>403</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="41">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>404</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>41</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>404</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="42">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>405</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>42</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>405</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="43">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>406</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>43</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>406</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="44">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>407</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>44</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>407</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="45">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>408</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>45</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>408</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="46">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>409</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>46</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>409</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="47">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>410</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>47</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>410</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="48">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>411</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>48</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>411</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="49">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>412</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>49</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>412</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="50">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>413</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>50</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>413</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="51">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>414</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>51</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>414</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="52">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>415</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>52</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>415</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="53">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>416</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>53</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>416</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="54">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>417</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>54</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>417</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="55">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>418</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>55</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>418</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="56">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>419</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>56</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>419</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="57">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>420</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>57</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>420</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="58">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>421</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>58</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>421</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="59">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>422</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>59</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>422</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="60">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>423</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>60</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>423</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="61">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>424</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>61</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>424</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="62">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>425</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>62</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>425</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="63">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>426</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>63</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>426</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="64">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>427</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>64</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>427</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="65">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>428</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>65</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>428</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="66">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>429</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>66</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>429</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="67">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>430</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>67</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>430</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="68">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>431</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>68</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>431</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="69">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>432</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>69</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>432</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="70">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>433</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>70</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>433</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="71">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>434</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>71</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>434</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="72">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>435</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>72</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>435</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="73">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>436</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>73</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>436</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="74">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>437</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>74</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>437</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="75">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>438</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>75</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>438</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="76">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>439</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>76</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>439</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="77">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>440</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>77</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>440</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="78">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>441</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>78</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>441</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="79">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>442</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>79</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>442</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="80">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>443</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>80</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>443</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="81">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>444</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>81</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>444</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="82">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>445</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>82</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>445</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="83">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>446</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>83</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>446</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="84">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>447</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>84</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>447</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="85">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>448</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>85</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>448</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="86">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>449</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>86</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>449</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="87">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>450</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>87</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>450</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="88">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>451</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>88</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>451</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="89">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>452</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>89</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>452</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="90">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>453</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>90</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>453</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
   </PDBx:pdbx_poly_seq_schemeCategory>
   <PDBx:pdbx_struct_assemblyCategory>
      <PDBx:pdbx_struct_assembly id="1">
         <PDBx:details>author_defined_assembly</PDBx:details>
         <PDBx:oligomeric_count>1</PDBx:oligomeric_count>
         <PDBx:oligomeric_details>monomeric</PDBx:oligomeric_details>
      </PDBx:pdbx_struct_assembly>
   </PDBx:pdbx_struct_assemblyCategory>
   <PDBx:pdbx_struct_assembly_genCategory>
      <PDBx:pdbx_struct_assembly_gen assembly_id="1" asym_id_list="A" oper_expression="1"></PDBx:pdbx_struct_assembly_gen>
   </PDBx:pdbx_struct_assembly_genCategory>
   <PDBx:pdbx_struct_oper_listCategory>
      <PDBx:pdbx_struct_oper_list id="1">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>1.0000000000</PDBx:matrix33>
         <PDBx:name>1_555</PDBx:name>
         <PDBx:symmetry_operation>x,y,z</PDBx:symmetry_operation>
         <PDBx:type>identity operation</PDBx:type>
         <PDBx:vector1>0.0000000000</PDBx:vector1>
         <PDBx:vector2>0.0000000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
   </PDBx:pdbx_struct_oper_listCategory>
   <PDBx:pdbx_struct_sheet_hbondCategory>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="1" range_id_2="2" sheet_id="A">
         <PDBx:range_1_auth_asym_id>A</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>N</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>HIS</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>386</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>N</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>HIS</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>23</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>A</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>O</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>ARG</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>405</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>O</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>ARG</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>42</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="2" range_id_2="3" sheet_id="A">
         <PDBx:range_1_auth_asym_id>A</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>N</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>CYS</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>404</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>N</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>CYS</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>41</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>A</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>O</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>LEU</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>412</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>O</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>LEU</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>49</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
   </PDBx:pdbx_struct_sheet_hbondCategory>
   <PDBx:pdbx_validate_close_contactCategory>
      <PDBx:pdbx_validate_close_contact id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>421</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>425</PDBx:auth_seq_id_2>
         <PDBx:dist>1.47</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="2">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>406</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>409</PDBx:auth_seq_id_2>
         <PDBx:dist>1.58</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="3">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>421</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>425</PDBx:auth_seq_id_2>
         <PDBx:dist>1.49</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="4">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>406</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>409</PDBx:auth_seq_id_2>
         <PDBx:dist>1.53</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="5">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>429</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>433</PDBx:auth_seq_id_2>
         <PDBx:dist>1.56</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="6">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>421</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>425</PDBx:auth_seq_id_2>
         <PDBx:dist>1.46</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="7">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>429</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>433</PDBx:auth_seq_id_2>
         <PDBx:dist>1.50</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="8">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>406</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>409</PDBx:auth_seq_id_2>
         <PDBx:dist>1.56</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="9">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>429</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>433</PDBx:auth_seq_id_2>
         <PDBx:dist>1.44</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="10">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>421</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>425</PDBx:auth_seq_id_2>
         <PDBx:dist>1.51</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="11">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>406</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>409</PDBx:auth_seq_id_2>
         <PDBx:dist>1.57</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="12">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>421</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>425</PDBx:auth_seq_id_2>
         <PDBx:dist>1.46</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="13">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>406</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>409</PDBx:auth_seq_id_2>
         <PDBx:dist>1.56</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="14">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>421</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>425</PDBx:auth_seq_id_2>
         <PDBx:dist>1.48</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="15">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>406</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>409</PDBx:auth_seq_id_2>
         <PDBx:dist>1.56</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="16">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>429</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>433</PDBx:auth_seq_id_2>
         <PDBx:dist>1.56</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="17">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>421</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>425</PDBx:auth_seq_id_2>
         <PDBx:dist>1.48</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="18">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>429</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>433</PDBx:auth_seq_id_2>
         <PDBx:dist>1.49</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="19">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>406</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>409</PDBx:auth_seq_id_2>
         <PDBx:dist>1.54</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="20">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>429</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>433</PDBx:auth_seq_id_2>
         <PDBx:dist>1.44</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="21">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>421</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>425</PDBx:auth_seq_id_2>
         <PDBx:dist>1.48</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="22">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>406</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>409</PDBx:auth_seq_id_2>
         <PDBx:dist>1.57</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="23">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>391</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>400</PDBx:auth_seq_id_2>
         <PDBx:dist>1.59</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="24">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>421</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>425</PDBx:auth_seq_id_2>
         <PDBx:dist>1.50</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="25">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>406</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>409</PDBx:auth_seq_id_2>
         <PDBx:dist>1.55</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="26">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>429</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>433</PDBx:auth_seq_id_2>
         <PDBx:dist>1.58</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="27">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>429</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>433</PDBx:auth_seq_id_2>
         <PDBx:dist>1.44</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="28">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>421</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>425</PDBx:auth_seq_id_2>
         <PDBx:dist>1.49</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="29">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>391</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>400</PDBx:auth_seq_id_2>
         <PDBx:dist>1.54</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="30">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>406</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>409</PDBx:auth_seq_id_2>
         <PDBx:dist>1.55</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="31">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>421</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>425</PDBx:auth_seq_id_2>
         <PDBx:dist>1.48</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="32">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>429</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>433</PDBx:auth_seq_id_2>
         <PDBx:dist>1.48</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="33">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>383</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>407</PDBx:auth_seq_id_2>
         <PDBx:dist>1.55</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="34">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>391</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>400</PDBx:auth_seq_id_2>
         <PDBx:dist>1.56</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="35">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>406</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>409</PDBx:auth_seq_id_2>
         <PDBx:dist>1.58</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="36">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>429</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>433</PDBx:auth_seq_id_2>
         <PDBx:dist>1.45</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="37">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>421</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>425</PDBx:auth_seq_id_2>
         <PDBx:dist>1.46</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="38">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>406</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>409</PDBx:auth_seq_id_2>
         <PDBx:dist>1.51</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="39">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>421</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>425</PDBx:auth_seq_id_2>
         <PDBx:dist>1.44</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="40">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>406</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>409</PDBx:auth_seq_id_2>
         <PDBx:dist>1.53</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="41">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>429</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>433</PDBx:auth_seq_id_2>
         <PDBx:dist>1.58</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="42">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>429</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>433</PDBx:auth_seq_id_2>
         <PDBx:dist>1.44</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="43">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>406</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>409</PDBx:auth_seq_id_2>
         <PDBx:dist>1.53</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="44">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>421</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>425</PDBx:auth_seq_id_2>
         <PDBx:dist>1.54</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="45">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>421</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>425</PDBx:auth_seq_id_2>
         <PDBx:dist>1.52</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="46">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>406</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>409</PDBx:auth_seq_id_2>
         <PDBx:dist>1.58</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="47">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>429</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>433</PDBx:auth_seq_id_2>
         <PDBx:dist>1.59</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="48">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>421</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>425</PDBx:auth_seq_id_2>
         <PDBx:dist>1.51</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="49">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>429</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>433</PDBx:auth_seq_id_2>
         <PDBx:dist>1.52</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="50">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>383</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>407</PDBx:auth_seq_id_2>
         <PDBx:dist>1.58</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="51">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>406</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>409</PDBx:auth_seq_id_2>
         <PDBx:dist>1.58</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="52">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>421</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>425</PDBx:auth_seq_id_2>
         <PDBx:dist>1.46</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="53">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>429</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>433</PDBx:auth_seq_id_2>
         <PDBx:dist>1.55</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="54">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>406</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>409</PDBx:auth_seq_id_2>
         <PDBx:dist>1.56</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="55">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>429</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>433</PDBx:auth_seq_id_2>
         <PDBx:dist>1.46</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="56">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>421</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>425</PDBx:auth_seq_id_2>
         <PDBx:dist>1.46</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="57">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>406</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>409</PDBx:auth_seq_id_2>
         <PDBx:dist>1.56</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="58">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>421</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>425</PDBx:auth_seq_id_2>
         <PDBx:dist>1.49</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="59">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>383</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>407</PDBx:auth_seq_id_2>
         <PDBx:dist>1.56</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="60">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>421</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>425</PDBx:auth_seq_id_2>
         <PDBx:dist>1.47</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="61">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>420</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>424</PDBx:auth_seq_id_2>
         <PDBx:dist>1.51</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="62">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>406</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>409</PDBx:auth_seq_id_2>
         <PDBx:dist>1.52</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
   </PDBx:pdbx_validate_close_contactCategory>
   <PDBx:pdbx_validate_torsionCategory>
      <PDBx:pdbx_validate_torsion id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>384</PDBx:auth_seq_id>
         <PDBx:phi>30.74</PDBx:phi>
         <PDBx:psi>46.33</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="2">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>-78.00</PDBx:phi>
         <PDBx:psi>42.56</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="3">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>414</PDBx:auth_seq_id>
         <PDBx:phi>-162.04</PDBx:phi>
         <PDBx:psi>115.74</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="4">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:phi>-87.80</PDBx:phi>
         <PDBx:psi>32.92</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="5">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>365</PDBx:auth_seq_id>
         <PDBx:phi>64.71</PDBx:phi>
         <PDBx:psi>151.47</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="6">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>380</PDBx:auth_seq_id>
         <PDBx:phi>-174.41</PDBx:phi>
         <PDBx:psi>129.81</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="7">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>384</PDBx:auth_seq_id>
         <PDBx:phi>30.32</PDBx:phi>
         <PDBx:psi>48.09</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="8">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>-79.48</PDBx:phi>
         <PDBx:psi>45.69</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="9">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>411</PDBx:auth_seq_id>
         <PDBx:phi>-55.93</PDBx:phi>
         <PDBx:psi>99.55</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="10">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:phi>-89.18</PDBx:phi>
         <PDBx:psi>32.78</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="11">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>448</PDBx:auth_seq_id>
         <PDBx:phi>-33.72</PDBx:phi>
         <PDBx:psi>123.38</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="12">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>450</PDBx:auth_seq_id>
         <PDBx:phi>-91.38</PDBx:phi>
         <PDBx:psi>-155.24</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="13">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:phi>52.67</PDBx:phi>
         <PDBx:psi>91.88</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="14">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>384</PDBx:auth_seq_id>
         <PDBx:phi>30.69</PDBx:phi>
         <PDBx:psi>51.93</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="15">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>-81.79</PDBx:phi>
         <PDBx:psi>48.68</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="16">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:phi>-90.67</PDBx:phi>
         <PDBx:psi>33.16</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="17">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:phi>-165.37</PDBx:phi>
         <PDBx:psi>62.18</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="18">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>452</PDBx:auth_seq_id>
         <PDBx:phi>62.46</PDBx:phi>
         <PDBx:psi>-88.04</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="19">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>365</PDBx:auth_seq_id>
         <PDBx:phi>165.55</PDBx:phi>
         <PDBx:psi>-60.36</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="20">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>384</PDBx:auth_seq_id>
         <PDBx:phi>23.94</PDBx:phi>
         <PDBx:psi>61.93</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="21">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>-79.80</PDBx:phi>
         <PDBx:psi>44.38</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="22">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:phi>-93.84</PDBx:phi>
         <PDBx:psi>32.40</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="23">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>448</PDBx:auth_seq_id>
         <PDBx:phi>-43.20</PDBx:phi>
         <PDBx:psi>102.94</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="24">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>367</PDBx:auth_seq_id>
         <PDBx:phi>-55.66</PDBx:phi>
         <PDBx:psi>-171.11</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="25">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>384</PDBx:auth_seq_id>
         <PDBx:phi>25.04</PDBx:phi>
         <PDBx:psi>62.07</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="26">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>-75.79</PDBx:phi>
         <PDBx:psi>49.93</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="27">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:phi>-95.61</PDBx:phi>
         <PDBx:psi>32.29</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="28">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:phi>177.13</PDBx:phi>
         <PDBx:psi>-53.40</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="29">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>452</PDBx:auth_seq_id>
         <PDBx:phi>79.37</PDBx:phi>
         <PDBx:psi>-58.98</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="30">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>383</PDBx:auth_seq_id>
         <PDBx:phi>-97.82</PDBx:phi>
         <PDBx:psi>40.53</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="31">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>384</PDBx:auth_seq_id>
         <PDBx:phi>-56.30</PDBx:phi>
         <PDBx:psi>79.01</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="32">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>-69.48</PDBx:phi>
         <PDBx:psi>50.24</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="33">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:phi>-88.01</PDBx:phi>
         <PDBx:psi>33.43</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="34">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>449</PDBx:auth_seq_id>
         <PDBx:phi>-75.83</PDBx:phi>
         <PDBx:psi>48.91</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="35">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>450</PDBx:auth_seq_id>
         <PDBx:phi>66.84</PDBx:phi>
         <PDBx:psi>134.18</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="36">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>383</PDBx:auth_seq_id>
         <PDBx:phi>-89.74</PDBx:phi>
         <PDBx:psi>40.64</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="37">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>384</PDBx:auth_seq_id>
         <PDBx:phi>-40.05</PDBx:phi>
         <PDBx:psi>83.83</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="38">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>-80.12</PDBx:phi>
         <PDBx:psi>43.94</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="39">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:phi>-87.20</PDBx:phi>
         <PDBx:psi>32.83</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="40">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>448</PDBx:auth_seq_id>
         <PDBx:phi>-33.11</PDBx:phi>
         <PDBx:psi>128.54</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="41">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>450</PDBx:auth_seq_id>
         <PDBx:phi>170.60</PDBx:phi>
         <PDBx:psi>-86.33</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="42">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:phi>64.67</PDBx:phi>
         <PDBx:psi>92.66</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="43">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>452</PDBx:auth_seq_id>
         <PDBx:phi>-154.80</PDBx:phi>
         <PDBx:psi>-40.45</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="44">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>365</PDBx:auth_seq_id>
         <PDBx:phi>65.23</PDBx:phi>
         <PDBx:psi>104.26</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="45">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>367</PDBx:auth_seq_id>
         <PDBx:phi>-56.01</PDBx:phi>
         <PDBx:psi>-175.84</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="46">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>384</PDBx:auth_seq_id>
         <PDBx:phi>30.11</PDBx:phi>
         <PDBx:psi>83.32</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="47">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>-80.19</PDBx:phi>
         <PDBx:psi>45.66</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="48">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:phi>-88.29</PDBx:phi>
         <PDBx:psi>33.10</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="49">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>448</PDBx:auth_seq_id>
         <PDBx:phi>-33.02</PDBx:phi>
         <PDBx:psi>95.17</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="50">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:phi>69.78</PDBx:phi>
         <PDBx:psi>111.08</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="51">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>452</PDBx:auth_seq_id>
         <PDBx:phi>-140.07</PDBx:phi>
         <PDBx:psi>-71.43</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="52">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>365</PDBx:auth_seq_id>
         <PDBx:phi>64.39</PDBx:phi>
         <PDBx:psi>122.43</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="53">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>367</PDBx:auth_seq_id>
         <PDBx:phi>-50.53</PDBx:phi>
         <PDBx:psi>-178.57</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="54">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>384</PDBx:auth_seq_id>
         <PDBx:phi>32.21</PDBx:phi>
         <PDBx:psi>48.73</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="55">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:phi>-85.65</PDBx:phi>
         <PDBx:psi>33.80</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="56">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>450</PDBx:auth_seq_id>
         <PDBx:phi>-162.81</PDBx:phi>
         <PDBx:psi>112.03</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="57">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>452</PDBx:auth_seq_id>
         <PDBx:phi>57.21</PDBx:phi>
         <PDBx:psi>-89.80</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="58">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>384</PDBx:auth_seq_id>
         <PDBx:phi>33.39</PDBx:phi>
         <PDBx:psi>47.62</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="59">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:phi>-90.60</PDBx:phi>
         <PDBx:psi>32.72</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="60">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>448</PDBx:auth_seq_id>
         <PDBx:phi>-163.19</PDBx:phi>
         <PDBx:psi>116.13</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="61">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>450</PDBx:auth_seq_id>
         <PDBx:phi>-154.52</PDBx:phi>
         <PDBx:psi>-85.98</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="62">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:phi>89.87</PDBx:phi>
         <PDBx:psi>101.63</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="63">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>384</PDBx:auth_seq_id>
         <PDBx:phi>31.46</PDBx:phi>
         <PDBx:psi>48.40</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="64">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>-78.39</PDBx:phi>
         <PDBx:psi>46.84</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="65">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>448</PDBx:auth_seq_id>
         <PDBx:phi>32.83</PDBx:phi>
         <PDBx:psi>60.34</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="66">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>450</PDBx:auth_seq_id>
         <PDBx:phi>-97.12</PDBx:phi>
         <PDBx:psi>33.57</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="67">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>452</PDBx:auth_seq_id>
         <PDBx:phi>64.92</PDBx:phi>
         <PDBx:psi>-84.49</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="68">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>366</PDBx:auth_seq_id>
         <PDBx:phi>60.60</PDBx:phi>
         <PDBx:psi>154.74</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="69">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>384</PDBx:auth_seq_id>
         <PDBx:phi>20.37</PDBx:phi>
         <PDBx:psi>50.91</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="70">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>-82.22</PDBx:phi>
         <PDBx:psi>42.21</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="71">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>411</PDBx:auth_seq_id>
         <PDBx:phi>-60.18</PDBx:phi>
         <PDBx:psi>98.90</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="72">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:phi>-91.87</PDBx:phi>
         <PDBx:psi>31.43</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="73">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>448</PDBx:auth_seq_id>
         <PDBx:phi>-161.43</PDBx:phi>
         <PDBx:psi>93.19</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="74">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>450</PDBx:auth_seq_id>
         <PDBx:phi>81.98</PDBx:phi>
         <PDBx:psi>53.92</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="75">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>452</PDBx:auth_seq_id>
         <PDBx:phi>78.62</PDBx:phi>
         <PDBx:psi>-70.32</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="76">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>365</PDBx:auth_seq_id>
         <PDBx:phi>-45.11</PDBx:phi>
         <PDBx:psi>166.61</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="77">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>366</PDBx:auth_seq_id>
         <PDBx:phi>-123.31</PDBx:phi>
         <PDBx:psi>-168.48</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="78">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>367</PDBx:auth_seq_id>
         <PDBx:phi>-62.78</PDBx:phi>
         <PDBx:psi>-176.55</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="79">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>384</PDBx:auth_seq_id>
         <PDBx:phi>32.45</PDBx:phi>
         <PDBx:psi>47.32</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="80">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>420</PDBx:auth_seq_id>
         <PDBx:phi>-49.57</PDBx:phi>
         <PDBx:psi>-18.97</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="81">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:phi>-94.49</PDBx:phi>
         <PDBx:psi>32.10</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="82">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>366</PDBx:auth_seq_id>
         <PDBx:phi>65.19</PDBx:phi>
         <PDBx:psi>147.68</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="83">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>383</PDBx:auth_seq_id>
         <PDBx:phi>-104.61</PDBx:phi>
         <PDBx:psi>41.84</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="84">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>384</PDBx:auth_seq_id>
         <PDBx:phi>-43.53</PDBx:phi>
         <PDBx:psi>85.39</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="85">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>-81.63</PDBx:phi>
         <PDBx:psi>44.43</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="86">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:phi>-87.57</PDBx:phi>
         <PDBx:psi>33.29</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="87">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>450</PDBx:auth_seq_id>
         <PDBx:phi>163.64</PDBx:phi>
         <PDBx:psi>78.20</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="88">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>452</PDBx:auth_seq_id>
         <PDBx:phi>162.13</PDBx:phi>
         <PDBx:psi>-68.61</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="89">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>383</PDBx:auth_seq_id>
         <PDBx:phi>-88.80</PDBx:phi>
         <PDBx:psi>40.88</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="90">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>384</PDBx:auth_seq_id>
         <PDBx:phi>-35.42</PDBx:phi>
         <PDBx:psi>82.98</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="91">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>-76.66</PDBx:phi>
         <PDBx:psi>48.04</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="92">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>414</PDBx:auth_seq_id>
         <PDBx:phi>-163.94</PDBx:phi>
         <PDBx:psi>114.30</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="93">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>448</PDBx:auth_seq_id>
         <PDBx:phi>-26.77</PDBx:phi>
         <PDBx:psi>121.45</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="94">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:phi>-167.06</PDBx:phi>
         <PDBx:psi>35.11</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="95">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>452</PDBx:auth_seq_id>
         <PDBx:phi>67.79</PDBx:phi>
         <PDBx:psi>166.55</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="96">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>365</PDBx:auth_seq_id>
         <PDBx:phi>54.24</PDBx:phi>
         <PDBx:psi>-172.97</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="97">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>384</PDBx:auth_seq_id>
         <PDBx:phi>38.14</PDBx:phi>
         <PDBx:psi>41.04</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="98">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>-78.04</PDBx:phi>
         <PDBx:psi>47.37</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="99">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>446</PDBx:auth_seq_id>
         <PDBx:phi>-69.77</PDBx:phi>
         <PDBx:psi>9.79</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="100">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>448</PDBx:auth_seq_id>
         <PDBx:phi>-36.13</PDBx:phi>
         <PDBx:psi>98.15</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="101">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>450</PDBx:auth_seq_id>
         <PDBx:phi>-47.16</PDBx:phi>
         <PDBx:psi>-71.50</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="102">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:phi>-66.62</PDBx:phi>
         <PDBx:psi>-177.64</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="103">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>452</PDBx:auth_seq_id>
         <PDBx:phi>68.16</PDBx:phi>
         <PDBx:psi>-69.95</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="104">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>365</PDBx:auth_seq_id>
         <PDBx:phi>69.33</PDBx:phi>
         <PDBx:psi>106.09</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="105">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>367</PDBx:auth_seq_id>
         <PDBx:phi>-110.28</PDBx:phi>
         <PDBx:psi>-169.39</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="106">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>383</PDBx:auth_seq_id>
         <PDBx:phi>-88.05</PDBx:phi>
         <PDBx:psi>40.99</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="107">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>384</PDBx:auth_seq_id>
         <PDBx:phi>-39.37</PDBx:phi>
         <PDBx:psi>87.71</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="108">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>-78.76</PDBx:phi>
         <PDBx:psi>49.12</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="109">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:phi>-91.24</PDBx:phi>
         <PDBx:psi>31.78</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="110">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>450</PDBx:auth_seq_id>
         <PDBx:phi>169.56</PDBx:phi>
         <PDBx:psi>-57.87</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="111">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:phi>50.12</PDBx:phi>
         <PDBx:psi>107.49</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="112">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>384</PDBx:auth_seq_id>
         <PDBx:phi>24.25</PDBx:phi>
         <PDBx:psi>63.13</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="113">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>-81.31</PDBx:phi>
         <PDBx:psi>43.93</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="114">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>446</PDBx:auth_seq_id>
         <PDBx:phi>-66.75</PDBx:phi>
         <PDBx:psi>3.03</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="115">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>448</PDBx:auth_seq_id>
         <PDBx:phi>-34.95</PDBx:phi>
         <PDBx:psi>104.68</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="116">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>452</PDBx:auth_seq_id>
         <PDBx:phi>64.76</PDBx:phi>
         <PDBx:psi>-80.66</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="117">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>384</PDBx:auth_seq_id>
         <PDBx:phi>38.32</PDBx:phi>
         <PDBx:psi>40.33</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="118">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>-74.43</PDBx:phi>
         <PDBx:psi>46.10</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="119">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>414</PDBx:auth_seq_id>
         <PDBx:phi>-161.52</PDBx:phi>
         <PDBx:psi>115.79</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="120">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:phi>-93.58</PDBx:phi>
         <PDBx:psi>33.17</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="121">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>448</PDBx:auth_seq_id>
         <PDBx:phi>-9.90</PDBx:phi>
         <PDBx:psi>123.52</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="122">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>449</PDBx:auth_seq_id>
         <PDBx:phi>-58.89</PDBx:phi>
         <PDBx:psi>64.56</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="123">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>450</PDBx:auth_seq_id>
         <PDBx:phi>64.98</PDBx:phi>
         <PDBx:psi>110.21</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="124">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:phi>174.15</PDBx:phi>
         <PDBx:psi>41.56</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="125">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>452</PDBx:auth_seq_id>
         <PDBx:phi>66.29</PDBx:phi>
         <PDBx:psi>-81.32</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="126">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>366</PDBx:auth_seq_id>
         <PDBx:phi>-109.36</PDBx:phi>
         <PDBx:psi>-166.36</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="127">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>383</PDBx:auth_seq_id>
         <PDBx:phi>-89.42</PDBx:phi>
         <PDBx:psi>41.41</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="128">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>384</PDBx:auth_seq_id>
         <PDBx:phi>-46.10</PDBx:phi>
         <PDBx:psi>80.54</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="129">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>-77.58</PDBx:phi>
         <PDBx:psi>45.07</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="130">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>411</PDBx:auth_seq_id>
         <PDBx:phi>-51.79</PDBx:phi>
         <PDBx:psi>93.85</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="131">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:phi>-88.00</PDBx:phi>
         <PDBx:psi>31.37</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="132">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>450</PDBx:auth_seq_id>
         <PDBx:phi>-161.42</PDBx:phi>
         <PDBx:psi>76.47</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="133">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>452</PDBx:auth_seq_id>
         <PDBx:phi>-178.47</PDBx:phi>
         <PDBx:psi>-39.71</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
   </PDBx:pdbx_validate_torsionCategory>
   <PDBx:pdbx_versionCategory>
      <PDBx:pdbx_version entry_id="2LUQ" major_version="4" minor_version="0000" revision_type="Initial release">
         <PDBx:details>Initial release</PDBx:details>
         <PDBx:revision_date>2012-12-05</PDBx:revision_date>
      </PDBx:pdbx_version>
      <PDBx:pdbx_version entry_id="2LUQ" major_version="4" minor_version="0001" revision_type="Citation">
         <PDBx:details>Citation update</PDBx:details>
         <PDBx:revision_date>2012-12-19</PDBx:revision_date>
      </PDBx:pdbx_version>
      <PDBx:pdbx_version entry_id="2LUQ" major_version="4" minor_version="0002" revision_type="Citation">
         <PDBx:details>Citation update</PDBx:details>
         <PDBx:revision_date>2013-02-13</PDBx:revision_date>
      </PDBx:pdbx_version>
   </PDBx:pdbx_versionCategory>
   <PDBx:structCategory>
      <PDBx:struct entry_id="2LUQ">
         <PDBx:pdbx_descriptor>Ribonuclease 3</PDBx:pdbx_descriptor>
         <PDBx:title>Solution structure of double-stranded RNA binding domain of S.cerevisiae RNase III (rnt1p)</PDBx:title>
      </PDBx:struct>
   </PDBx:structCategory>
   <PDBx:struct_asymCategory>
      <PDBx:struct_asym id="A">
         <PDBx:entity_id>1</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
   </PDBx:struct_asymCategory>
   <PDBx:struct_biolCategory>
      <PDBx:struct_biol id="1">
      </PDBx:struct_biol>
   </PDBx:struct_biolCategory>
   <PDBx:struct_confCategory>
      <PDBx:struct_conf id="HELX_P1">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ASN</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>369</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ASN</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>6</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ILE</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>378</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ILE</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>15</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>1</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>10</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P2">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ASN</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>419</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ASN</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>56</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ASP</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>434</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ASP</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>71</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>2</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>16</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P3">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ASP</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>434</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ASP</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>71</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ALA</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>447</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ALA</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>84</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>3</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>14</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
   </PDBx:struct_confCategory>
   <PDBx:struct_conf_typeCategory>
      <PDBx:struct_conf_type id="HELX_P">
      </PDBx:struct_conf_type>
   </PDBx:struct_conf_typeCategory>
   <PDBx:struct_keywordsCategory>
      <PDBx:struct_keywords entry_id="2LUQ">
         <PDBx:pdbx_keywords>RNA BINDING PROTEIN</PDBx:pdbx_keywords>
         <PDBx:text>DSRBD, RNT1P, RNA BINDING PROTEIN</PDBx:text>
      </PDBx:struct_keywords>
   </PDBx:struct_keywordsCategory>
   <PDBx:struct_refCategory>
      <PDBx:struct_ref id="1">
         <PDBx:biol_id xsi:nil="true" />
         <PDBx:db_code>RNT1_YEAST</PDBx:db_code>
         <PDBx:db_name>UNP</PDBx:db_name>
         <PDBx:entity_id>1</PDBx:entity_id>
         <PDBx:pdbx_align_begin>366</PDBx:pdbx_align_begin>
         <PDBx:pdbx_db_accession>Q02555</PDBx:pdbx_db_accession>
         <PDBx:pdbx_seq_one_letter_code>LDMNAKRQLYSLIGYASLRLHYVTVKKPTAVDPNSIVECRVGDGTVLGTGVGRNIKIAGI 
RAAENALRDKKMLDFYAKQRAAIPRSES</PDBx:pdbx_seq_one_letter_code>
      </PDBx:struct_ref>
   </PDBx:struct_refCategory>
   <PDBx:struct_ref_seqCategory>
      <PDBx:struct_ref_seq align_id="1">
         <PDBx:db_align_beg>366</PDBx:db_align_beg>
         <PDBx:db_align_end>453</PDBx:db_align_end>
         <PDBx:pdbx_PDB_id_code>2LUQ</PDBx:pdbx_PDB_id_code>
         <PDBx:pdbx_auth_seq_align_beg>366</PDBx:pdbx_auth_seq_align_beg>
         <PDBx:pdbx_auth_seq_align_end>453</PDBx:pdbx_auth_seq_align_end>
         <PDBx:pdbx_db_accession>Q02555</PDBx:pdbx_db_accession>
         <PDBx:pdbx_strand_id>A</PDBx:pdbx_strand_id>
         <PDBx:ref_id>1</PDBx:ref_id>
         <PDBx:seq_align_beg>3</PDBx:seq_align_beg>
         <PDBx:seq_align_end>90</PDBx:seq_align_end>
      </PDBx:struct_ref_seq>
   </PDBx:struct_ref_seqCategory>
   <PDBx:struct_ref_seq_difCategory>
      <PDBx:struct_ref_seq_dif pdbx_ordinal="1">
         <PDBx:align_id>1</PDBx:align_id>
         <PDBx:details>EXPRESSION TAG</PDBx:details>
         <PDBx:mon_id>GLY</PDBx:mon_id>
         <PDBx:pdbx_auth_seq_num>364</PDBx:pdbx_auth_seq_num>
         <PDBx:pdbx_pdb_id_code>2LUQ</PDBx:pdbx_pdb_id_code>
         <PDBx:pdbx_pdb_strand_id>A</PDBx:pdbx_pdb_strand_id>
         <PDBx:pdbx_seq_db_accession_code>Q02555</PDBx:pdbx_seq_db_accession_code>
         <PDBx:pdbx_seq_db_name>UNP</PDBx:pdbx_seq_db_name>
         <PDBx:seq_num>1</PDBx:seq_num>
      </PDBx:struct_ref_seq_dif>
      <PDBx:struct_ref_seq_dif pdbx_ordinal="2">
         <PDBx:align_id>1</PDBx:align_id>
         <PDBx:details>EXPRESSION TAG</PDBx:details>
         <PDBx:mon_id>SER</PDBx:mon_id>
         <PDBx:pdbx_auth_seq_num>365</PDBx:pdbx_auth_seq_num>
         <PDBx:pdbx_pdb_id_code>2LUQ</PDBx:pdbx_pdb_id_code>
         <PDBx:pdbx_pdb_strand_id>A</PDBx:pdbx_pdb_strand_id>
         <PDBx:pdbx_seq_db_accession_code>Q02555</PDBx:pdbx_seq_db_accession_code>
         <PDBx:pdbx_seq_db_name>UNP</PDBx:pdbx_seq_db_name>
         <PDBx:seq_num>2</PDBx:seq_num>
      </PDBx:struct_ref_seq_dif>
   </PDBx:struct_ref_seq_difCategory>
   <PDBx:struct_sheetCategory>
      <PDBx:struct_sheet id="A">
         <PDBx:number_strands>3</PDBx:number_strands>
      </PDBx:struct_sheet>
   </PDBx:struct_sheetCategory>
   <PDBx:struct_sheet_orderCategory>
      <PDBx:struct_sheet_order range_id_1="1" range_id_2="2" sheet_id="A">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="2" range_id_2="3" sheet_id="A">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
   </PDBx:struct_sheet_orderCategory>
   <PDBx:struct_sheet_rangeCategory>
      <PDBx:struct_sheet_range id="1" sheet_id="A">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>HIS</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>386</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>HIS</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>23</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>PRO</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>393</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>PRO</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>30</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="2" sheet_id="A">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>PRO</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>398</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>PRO</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>35</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ARG</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>405</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ARG</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>42</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="3" sheet_id="A">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>VAL</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>411</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>VAL</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>48</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>GLY</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>417</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>GLY</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>54</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
   </PDBx:struct_sheet_rangeCategory>
</PDBx:datablock>
