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   <PDBx:atom_typeCategory>
      <PDBx:atom_type symbol="C"></PDBx:atom_type>
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   <PDBx:audit_authorCategory>
      <PDBx:audit_author pdbx_ordinal="1">
         <PDBx:name>Thirugnanasambandam, A.</PDBx:name>
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      <PDBx:audit_author pdbx_ordinal="2">
         <PDBx:name>Karthik, S.</PDBx:name>
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      <PDBx:audit_author pdbx_ordinal="3">
         <PDBx:name>Mandal, P.K.</PDBx:name>
      </PDBx:audit_author>
      <PDBx:audit_author pdbx_ordinal="4">
         <PDBx:name>Gautham, N.</PDBx:name>
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         <PDBx:dict_location>http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic</PDBx:dict_location>
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   <PDBx:cellCategory>
      <PDBx:cell entry_id="4ZKK">
         <PDBx:Z_PDB>12</PDBx:Z_PDB>
         <PDBx:angle_alpha>90.00</PDBx:angle_alpha>
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         <PDBx:formula>Co 2</PDBx:formula>
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         <PDBx:name>COBALT (II) ION</PDBx:name>
         <PDBx:type>non-polymer</PDBx:type>
      </PDBx:chem_comp>
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         <PDBx:name>2&apos;-DEOXYADENOSINE-5&apos;-MONOPHOSPHATE</PDBx:name>
         <PDBx:type>DNA linking</PDBx:type>
      </PDBx:chem_comp>
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         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>2&apos;-DEOXYCYTIDINE-5&apos;-MONOPHOSPHATE</PDBx:name>
         <PDBx:type>DNA linking</PDBx:type>
      </PDBx:chem_comp>
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         <PDBx:type>DNA linking</PDBx:type>
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         <PDBx:name>THYMIDINE-5&apos;-MONOPHOSPHATE</PDBx:name>
         <PDBx:type>DNA linking</PDBx:type>
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         <PDBx:name>WATER</PDBx:name>
         <PDBx:type>non-polymer</PDBx:type>
      </PDBx:chem_comp>
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   <PDBx:citationCategory>
      <PDBx:citation id="primary">
         <PDBx:country>US</PDBx:country>
         <PDBx:journal_abbrev>Acta Crystallogr.,Sect.D</PDBx:journal_abbrev>
         <PDBx:journal_id_ASTM>ABCRE6</PDBx:journal_id_ASTM>
         <PDBx:journal_id_ISSN>1399-0047</PDBx:journal_id_ISSN>
         <PDBx:journal_volume>71</PDBx:journal_volume>
         <PDBx:page_first>2119</PDBx:page_first>
         <PDBx:page_last>2126</PDBx:page_last>
         <PDBx:pdbx_database_id_DOI>10.1107/S1399004715013930</PDBx:pdbx_database_id_DOI>
         <PDBx:pdbx_database_id_PubMed>26457435</PDBx:pdbx_database_id_PubMed>
         <PDBx:title>The novel double-folded structure of d(GCATGCATGC): a possible model for triplet-repeat sequences</PDBx:title>
         <PDBx:year>2015</PDBx:year>
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   </PDBx:citationCategory>
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      <PDBx:citation_author citation_id="primary" name="Thirugnanasambandam, A." ordinal="1"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Karthik, S." ordinal="2"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Mandal, P.K." ordinal="3"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Gautham, N." ordinal="4"></PDBx:citation_author>
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   <PDBx:computingCategory>
      <PDBx:computing entry_id="4ZKK">
         <PDBx:structure_refinement>PHENIX (phenix.refine: 1.9_1692)</PDBx:structure_refinement>
      </PDBx:computing>
   </PDBx:computingCategory>
   <PDBx:database_2Category>
      <PDBx:database_2 database_code="4ZKK" database_id="PDB"></PDBx:database_2>
      <PDBx:database_2 database_code="D_1000209451" database_id="WWPDB"></PDBx:database_2>
   </PDBx:database_2Category>
   <PDBx:database_PDB_revCategory>
      <PDBx:database_PDB_rev num="1">
         <PDBx:date>2015-10-14</PDBx:date>
         <PDBx:date_original>2015-04-30</PDBx:date_original>
         <PDBx:mod_type>0</PDBx:mod_type>
         <PDBx:replaces>4ZKK</PDBx:replaces>
      </PDBx:database_PDB_rev>
      <PDBx:database_PDB_rev num="2">
         <PDBx:date>2016-01-20</PDBx:date>
         <PDBx:mod_type>1</PDBx:mod_type>
         <PDBx:replaces>4ZKK</PDBx:replaces>
      </PDBx:database_PDB_rev>
   </PDBx:database_PDB_revCategory>
   <PDBx:database_PDB_rev_recordCategory>
      <PDBx:database_PDB_rev_record rev_num="2" type="JRNL">
      </PDBx:database_PDB_rev_record>
   </PDBx:database_PDB_rev_recordCategory>
   <PDBx:diffrnCategory>
      <PDBx:diffrn id="1">
         <PDBx:ambient_temp>100</PDBx:ambient_temp>
         <PDBx:crystal_id>1</PDBx:crystal_id>
      </PDBx:diffrn>
   </PDBx:diffrnCategory>
   <PDBx:diffrn_detectorCategory>
      <PDBx:diffrn_detector diffrn_id="1">
         <PDBx:details>Bent collimating mirror &amp; toroid</PDBx:details>
         <PDBx:detector>CCD</PDBx:detector>
         <PDBx:pdbx_collection_date>2012-07-19</PDBx:pdbx_collection_date>
         <PDBx:type>MARMOSAIC 225 mm CCD</PDBx:type>
      </PDBx:diffrn_detector>
   </PDBx:diffrn_detectorCategory>
   <PDBx:diffrn_radiationCategory>
      <PDBx:diffrn_radiation diffrn_id="1">
         <PDBx:monochromator>Si(III) monochromator</PDBx:monochromator>
         <PDBx:pdbx_diffrn_protocol>SINGLE WAVELENGTH</PDBx:pdbx_diffrn_protocol>
         <PDBx:pdbx_monochromatic_or_laue_m_l>M</PDBx:pdbx_monochromatic_or_laue_m_l>
         <PDBx:pdbx_scattering_type>x-ray</PDBx:pdbx_scattering_type>
         <PDBx:wavelength_id>1</PDBx:wavelength_id>
      </PDBx:diffrn_radiation>
   </PDBx:diffrn_radiationCategory>
   <PDBx:diffrn_radiation_wavelengthCategory>
      <PDBx:diffrn_radiation_wavelength id="1">
         <PDBx:wavelength>1.604</PDBx:wavelength>
         <PDBx:wt>1.0</PDBx:wt>
      </PDBx:diffrn_radiation_wavelength>
   </PDBx:diffrn_radiation_wavelengthCategory>
   <PDBx:diffrn_sourceCategory>
      <PDBx:diffrn_source diffrn_id="1">
         <PDBx:pdbx_synchrotron_beamline>BM14</PDBx:pdbx_synchrotron_beamline>
         <PDBx:pdbx_synchrotron_site>ESRF</PDBx:pdbx_synchrotron_site>
         <PDBx:pdbx_wavelength_list>1.604</PDBx:pdbx_wavelength_list>
         <PDBx:source>SYNCHROTRON</PDBx:source>
         <PDBx:type>ESRF BEAMLINE BM14</PDBx:type>
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   </PDBx:diffrn_sourceCategory>
   <PDBx:entityCategory>
      <PDBx:entity id="1">
         <PDBx:formula_weight>3045.005</PDBx:formula_weight>
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         <PDBx:pdbx_number_of_molecules>1</PDBx:pdbx_number_of_molecules>
         <PDBx:src_method>syn</PDBx:src_method>
         <PDBx:type>polymer</PDBx:type>
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         <PDBx:pdbx_description>COBALT (II) ION</PDBx:pdbx_description>
         <PDBx:pdbx_number_of_molecules>3</PDBx:pdbx_number_of_molecules>
         <PDBx:src_method>syn</PDBx:src_method>
         <PDBx:type>non-polymer</PDBx:type>
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      <PDBx:entity id="3">
         <PDBx:formula_weight>18.015</PDBx:formula_weight>
         <PDBx:pdbx_description>water</PDBx:pdbx_description>
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         <PDBx:src_method>nat</PDBx:src_method>
         <PDBx:type>water</PDBx:type>
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   </PDBx:entityCategory>
   <PDBx:entity_polyCategory>
      <PDBx:entity_poly entity_id="1">
         <PDBx:nstd_linkage>no</PDBx:nstd_linkage>
         <PDBx:nstd_monomer>no</PDBx:nstd_monomer>
         <PDBx:pdbx_seq_one_letter_code>(DG)(DC)(DA)(DT)(DG)(DC)(DA)(DT)(DG)(DC)</PDBx:pdbx_seq_one_letter_code>
         <PDBx:pdbx_seq_one_letter_code_can>GCATGCATGC</PDBx:pdbx_seq_one_letter_code_can>
         <PDBx:pdbx_strand_id>A</PDBx:pdbx_strand_id>
         <PDBx:type>polydeoxyribonucleotide</PDBx:type>
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      <PDBx:entity_poly_seq entity_id="1" mon_id="DG" num="1">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="DC" num="2">
         <PDBx:hetero>n</PDBx:hetero>
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      <PDBx:entity_poly_seq entity_id="1" mon_id="DA" num="3">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
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         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
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         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="DC" num="6">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="DA" num="7">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="DT" num="8">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="DG" num="9">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
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         <PDBx:hetero>n</PDBx:hetero>
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      <PDBx:exptl entry_id="4ZKK" method="X-RAY DIFFRACTION">
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         <PDBx:density_Matthews>2.38</PDBx:density_Matthews>
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         <PDBx:description>hexagonal bipyramidal</PDBx:description>
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      <PDBx:exptl_crystal_grow crystal_id="1">
         <PDBx:method>VAPOR DIFFUSION, HANGING DROP</PDBx:method>
         <PDBx:pH>7.0</PDBx:pH>
         <PDBx:pdbx_details>1 mM DNA, 50 mM sodium cacodylate buffer, 10 mM cobalt chloride and equilibrated against 40&#37; MPD</PDBx:pdbx_details>
         <PDBx:temp>293</PDBx:temp>
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      <PDBx:ndb_struct_conf_na entry_id="4ZKK" feature="double helix"></PDBx:ndb_struct_conf_na>
      <PDBx:ndb_struct_conf_na entry_id="4ZKK" feature="hairpin loop"></PDBx:ndb_struct_conf_na>
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         <PDBx:buckle>-0.743</PDBx:buckle>
         <PDBx:i_auth_asym_id>A</PDBx:i_auth_asym_id>
         <PDBx:i_auth_seq_id>1</PDBx:i_auth_seq_id>
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         <PDBx:j_auth_seq_id>6</PDBx:j_auth_seq_id>
         <PDBx:opening>176.992</PDBx:opening>
         <PDBx:pair_name>A_DG1:DC6_A</PDBx:pair_name>
         <PDBx:pair_number>1</PDBx:pair_number>
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         <PDBx:stagger>-0.132</PDBx:stagger>
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      <PDBx:ndb_struct_na_base_pair i_label_asym_id="A" i_label_comp_id="DC" i_label_seq_id="2" i_symmetry="1_555" j_label_asym_id="A" j_label_comp_id="DG" j_label_seq_id="5" j_symmetry="1_555" model_number="1">
         <PDBx:buckle>-4.835</PDBx:buckle>
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         <PDBx:j_auth_seq_id>5</PDBx:j_auth_seq_id>
         <PDBx:opening>-178.301</PDBx:opening>
         <PDBx:pair_name>A_DC2:DG5_A</PDBx:pair_name>
         <PDBx:pair_number>2</PDBx:pair_number>
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      <PDBx:ndb_struct_na_base_pair_step i_label_asym_id_1="A" i_label_asym_id_2="A" i_label_comp_id_1="DG" i_label_comp_id_2="DC" i_label_seq_id_1="1" i_label_seq_id_2="2" i_symmetry_1="1_555" i_symmetry_2="1_555" j_label_asym_id_1="A" j_label_asym_id_2="A" j_label_comp_id_1="DC" j_label_comp_id_2="DG" j_label_seq_id_1="6" j_label_seq_id_2="5" j_symmetry_1="1_555" j_symmetry_2="1_555" model_number="1">
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         <PDBx:helical_twist>-150.362</PDBx:helical_twist>
         <PDBx:i_auth_asym_id_1>A</PDBx:i_auth_asym_id_1>
         <PDBx:i_auth_asym_id_2>A</PDBx:i_auth_asym_id_2>
         <PDBx:i_auth_seq_id_1>1</PDBx:i_auth_seq_id_1>
         <PDBx:i_auth_seq_id_2>2</PDBx:i_auth_seq_id_2>
         <PDBx:inclination>-0.140</PDBx:inclination>
         <PDBx:j_auth_asym_id_1>A</PDBx:j_auth_asym_id_1>
         <PDBx:j_auth_asym_id_2>A</PDBx:j_auth_asym_id_2>
         <PDBx:j_auth_seq_id_1>6</PDBx:j_auth_seq_id_1>
         <PDBx:j_auth_seq_id_2>5</PDBx:j_auth_seq_id_2>
         <PDBx:rise>2.884</PDBx:rise>
         <PDBx:roll>0.270</PDBx:roll>
         <PDBx:shift>-0.369</PDBx:shift>
         <PDBx:slide>-0.099</PDBx:slide>
         <PDBx:step_name>AA_DG1DC2:DG5DC6_AA</PDBx:step_name>
         <PDBx:step_number>1</PDBx:step_number>
         <PDBx:tilt>-3.585</PDBx:tilt>
         <PDBx:tip>-1.854</PDBx:tip>
         <PDBx:twist>-150.347</PDBx:twist>
         <PDBx:x_displacement>0.050</PDBx:x_displacement>
         <PDBx:y_displacement>-0.203</PDBx:y_displacement>
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      <PDBx:pdbx_database_status entry_id="4ZKK">
         <PDBx:SG_entry>N</PDBx:SG_entry>
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         <PDBx:deposit_site>RCSB</PDBx:deposit_site>
         <PDBx:pdb_format_compatible>Y</PDBx:pdb_format_compatible>
         <PDBx:process_site>RCSB</PDBx:process_site>
         <PDBx:status_code>REL</PDBx:status_code>
         <PDBx:status_code_sf>REL</PDBx:status_code_sf>
      </PDBx:pdbx_database_status>
   </PDBx:pdbx_database_statusCategory>
   <PDBx:pdbx_entity_nonpolyCategory>
      <PDBx:pdbx_entity_nonpoly entity_id="2">
         <PDBx:comp_id>CO</PDBx:comp_id>
         <PDBx:name>COBALT (II) ION</PDBx:name>
      </PDBx:pdbx_entity_nonpoly>
      <PDBx:pdbx_entity_nonpoly entity_id="3">
         <PDBx:comp_id>HOH</PDBx:comp_id>
         <PDBx:name>water</PDBx:name>
      </PDBx:pdbx_entity_nonpoly>
   </PDBx:pdbx_entity_nonpolyCategory>
   <PDBx:pdbx_entity_src_synCategory>
      <PDBx:pdbx_entity_src_syn entity_id="1" pdbx_src_id="1">
         <PDBx:ncbi_taxonomy_id>32630</PDBx:ncbi_taxonomy_id>
         <PDBx:organism_scientific>synthetic construct</PDBx:organism_scientific>
         <PDBx:pdbx_alt_source_flag>sample</PDBx:pdbx_alt_source_flag>
         <PDBx:pdbx_beg_seq_num>1</PDBx:pdbx_beg_seq_num>
         <PDBx:pdbx_end_seq_num>10</PDBx:pdbx_end_seq_num>
      </PDBx:pdbx_entity_src_syn>
   </PDBx:pdbx_entity_src_synCategory>
   <PDBx:pdbx_nonpoly_schemeCategory>
      <PDBx:pdbx_nonpoly_scheme asym_id="B" ndb_seq_num="1">
         <PDBx:auth_mon_id>CO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1</PDBx:auth_seq_num>
         <PDBx:entity_id>2</PDBx:entity_id>
         <PDBx:mon_id>CO</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>101</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="1">
         <PDBx:auth_mon_id>CO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2</PDBx:auth_seq_num>
         <PDBx:entity_id>2</PDBx:entity_id>
         <PDBx:mon_id>CO</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>102</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="1">
         <PDBx:auth_mon_id>CO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3</PDBx:auth_seq_num>
         <PDBx:entity_id>2</PDBx:entity_id>
         <PDBx:mon_id>CO</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>103</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="1">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>13</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>201</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="2">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>17</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>202</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="3">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>11</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>203</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="4">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>204</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="5">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>5</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>205</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="6">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>10</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>206</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="7">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>7</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>207</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="8">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>4</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>208</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="9">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>209</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="10">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>8</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>210</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="11">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>211</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="12">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>19</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>212</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="13">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>12</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>213</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="14">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>24</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>214</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="15">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>14</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>215</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="16">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>15</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>216</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="17">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>21</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>217</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="18">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>16</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>218</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="19">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>18</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>219</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="20">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>20</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>220</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="21">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>6</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>221</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="22">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>22</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>222</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="23">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>9</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>223</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="24">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>23</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>224</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
   </PDBx:pdbx_nonpoly_schemeCategory>
   <PDBx:pdbx_poly_seq_schemeCategory>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="DG" seq_id="1">
         <PDBx:auth_mon_id>DG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>1</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>DG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="DC" seq_id="2">
         <PDBx:auth_mon_id>DC</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>2</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>DC</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="DA" seq_id="3">
         <PDBx:auth_mon_id>DA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>3</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>DA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="DT" seq_id="4">
         <PDBx:auth_mon_id>DT</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>4</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>4</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>DT</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="DG" seq_id="5">
         <PDBx:auth_mon_id>DG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>5</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>5</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>DG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>5</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="DC" seq_id="6">
         <PDBx:auth_mon_id>DC</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>6</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>6</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>DC</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>6</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="DA" seq_id="7">
         <PDBx:auth_mon_id>DA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>7</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>7</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>DA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>7</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="DT" seq_id="8">
         <PDBx:auth_mon_id>DT</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>8</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>8</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>DT</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>8</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="DG" seq_id="9">
         <PDBx:auth_mon_id>DG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>9</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>9</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>DG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>9</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="DC" seq_id="10">
         <PDBx:auth_mon_id>DC</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>10</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>10</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>DC</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>10</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
   </PDBx:pdbx_poly_seq_schemeCategory>
   <PDBx:pdbx_refine_tlsCategory>
      <PDBx:pdbx_refine_tls id="1">
         <PDBx:L11>0.0159</PDBx:L11>
         <PDBx:L12>-0.0408</PDBx:L12>
         <PDBx:L13>0.0183</PDBx:L13>
         <PDBx:L22>0.1048</PDBx:L22>
         <PDBx:L23>-0.0495</PDBx:L23>
         <PDBx:L33>0.0238</PDBx:L33>
         <PDBx:S11>0.0784</PDBx:S11>
         <PDBx:S12>0.0005</PDBx:S12>
         <PDBx:S13>0.0068</PDBx:S13>
         <PDBx:S21>-0.0595</PDBx:S21>
         <PDBx:S22>-0.0981</PDBx:S22>
         <PDBx:S23>0.0549</PDBx:S23>
         <PDBx:S31>0.1063</PDBx:S31>
         <PDBx:S32>-0.0031</PDBx:S32>
         <PDBx:S33>0.0129</PDBx:S33>
         <PDBx:T11>0.0044</PDBx:T11>
         <PDBx:T12>-0.0627</PDBx:T12>
         <PDBx:T13>-0.0873</PDBx:T13>
         <PDBx:T22>0.5506</PDBx:T22>
         <PDBx:T23>0.0870</PDBx:T23>
         <PDBx:T33>0.1922</PDBx:T33>
         <PDBx:method>refined</PDBx:method>
         <PDBx:origin_x>6.0117</PDBx:origin_x>
         <PDBx:origin_y>10.5724</PDBx:origin_y>
         <PDBx:origin_z>-0.0368</PDBx:origin_z>
         <PDBx:pdbx_refine_id>X-RAY DIFFRACTION</PDBx:pdbx_refine_id>
      </PDBx:pdbx_refine_tls>
      <PDBx:pdbx_refine_tls id="2">
         <PDBx:L11>0.0480</PDBx:L11>
         <PDBx:L12>0.0175</PDBx:L12>
         <PDBx:L13>-0.0025</PDBx:L13>
         <PDBx:L22>0.0110</PDBx:L22>
         <PDBx:L23>0.0109</PDBx:L23>
         <PDBx:L33>0.0187</PDBx:L33>
         <PDBx:S11>0.0854</PDBx:S11>
         <PDBx:S12>-0.0473</PDBx:S12>
         <PDBx:S13>-0.0229</PDBx:S13>
         <PDBx:S21>0.0084</PDBx:S21>
         <PDBx:S22>-0.0772</PDBx:S22>
         <PDBx:S23>-0.1228</PDBx:S23>
         <PDBx:S31>0.1072</PDBx:S31>
         <PDBx:S32>0.0362</PDBx:S32>
         <PDBx:S33>0.0661</PDBx:S33>
         <PDBx:T11>-0.0821</PDBx:T11>
         <PDBx:T12>0.1266</PDBx:T12>
         <PDBx:T13>-0.0991</PDBx:T13>
         <PDBx:T22>0.8955</PDBx:T22>
         <PDBx:T23>0.0515</PDBx:T23>
         <PDBx:T33>0.2443</PDBx:T33>
         <PDBx:method>refined</PDBx:method>
         <PDBx:origin_x>11.1029</PDBx:origin_x>
         <PDBx:origin_y>10.2505</PDBx:origin_y>
         <PDBx:origin_z>0.9608</PDBx:origin_z>
         <PDBx:pdbx_refine_id>X-RAY DIFFRACTION</PDBx:pdbx_refine_id>
      </PDBx:pdbx_refine_tls>
      <PDBx:pdbx_refine_tls id="3">
         <PDBx:L11>0.0475</PDBx:L11>
         <PDBx:L12>0.0203</PDBx:L12>
         <PDBx:L13>0.0236</PDBx:L13>
         <PDBx:L22>0.0827</PDBx:L22>
         <PDBx:L23>-0.0151</PDBx:L23>
         <PDBx:L33>0.0213</PDBx:L33>
         <PDBx:S11>0.0346</PDBx:S11>
         <PDBx:S12>-0.1705</PDBx:S12>
         <PDBx:S13>-0.0299</PDBx:S13>
         <PDBx:S21>-0.0734</PDBx:S21>
         <PDBx:S22>0.1023</PDBx:S22>
         <PDBx:S23>-0.1550</PDBx:S23>
         <PDBx:S31>0.0610</PDBx:S31>
         <PDBx:S32>0.1609</PDBx:S32>
         <PDBx:S33>0.0259</PDBx:S33>
         <PDBx:T11>0.1375</PDBx:T11>
         <PDBx:T12>0.0626</PDBx:T12>
         <PDBx:T13>0.0003</PDBx:T13>
         <PDBx:T22>0.4396</PDBx:T22>
         <PDBx:T23>-0.0138</PDBx:T23>
         <PDBx:T33>0.3585</PDBx:T33>
         <PDBx:method>refined</PDBx:method>
         <PDBx:origin_x>12.8246</PDBx:origin_x>
         <PDBx:origin_y>12.1571</PDBx:origin_y>
         <PDBx:origin_z>-10.6452</PDBx:origin_z>
         <PDBx:pdbx_refine_id>X-RAY DIFFRACTION</PDBx:pdbx_refine_id>
      </PDBx:pdbx_refine_tls>
   </PDBx:pdbx_refine_tlsCategory>
   <PDBx:pdbx_refine_tls_groupCategory>
      <PDBx:pdbx_refine_tls_group id="1">
         <PDBx:pdbx_refine_id>X-RAY DIFFRACTION</PDBx:pdbx_refine_id>
         <PDBx:refine_tls_id>1</PDBx:refine_tls_id>
         <PDBx:selection_details>chain &apos;A&apos; and (resid 1 through 3 )</PDBx:selection_details>
      </PDBx:pdbx_refine_tls_group>
      <PDBx:pdbx_refine_tls_group id="2">
         <PDBx:pdbx_refine_id>X-RAY DIFFRACTION</PDBx:pdbx_refine_id>
         <PDBx:refine_tls_id>2</PDBx:refine_tls_id>
         <PDBx:selection_details>chain &apos;A&apos; and (resid 5 through 7 )</PDBx:selection_details>
      </PDBx:pdbx_refine_tls_group>
      <PDBx:pdbx_refine_tls_group id="3">
         <PDBx:pdbx_refine_id>X-RAY DIFFRACTION</PDBx:pdbx_refine_id>
         <PDBx:refine_tls_id>3</PDBx:refine_tls_id>
         <PDBx:selection_details>chain &apos;A&apos; and (resid 8 through 10 )</PDBx:selection_details>
      </PDBx:pdbx_refine_tls_group>
   </PDBx:pdbx_refine_tls_groupCategory>
   <PDBx:pdbx_struct_assemblyCategory>
      <PDBx:pdbx_struct_assembly id="1">
         <PDBx:details>author_and_software_defined_assembly</PDBx:details>
         <PDBx:method_details>PISA</PDBx:method_details>
         <PDBx:oligomeric_count>2</PDBx:oligomeric_count>
         <PDBx:oligomeric_details>dimeric</PDBx:oligomeric_details>
      </PDBx:pdbx_struct_assembly>
   </PDBx:pdbx_struct_assemblyCategory>
   <PDBx:pdbx_struct_assembly_genCategory>
      <PDBx:pdbx_struct_assembly_gen assembly_id="1" asym_id_list="A,B,C,D,E" oper_expression="1,2"></PDBx:pdbx_struct_assembly_gen>
   </PDBx:pdbx_struct_assembly_genCategory>
   <PDBx:pdbx_struct_assembly_propCategory>
      <PDBx:pdbx_struct_assembly_prop biol_id="1" type="ABSA (A^2)">
         <PDBx:value>1520</PDBx:value>
      </PDBx:pdbx_struct_assembly_prop>
      <PDBx:pdbx_struct_assembly_prop biol_id="1" type="MORE">
         <PDBx:value>-41</PDBx:value>
      </PDBx:pdbx_struct_assembly_prop>
      <PDBx:pdbx_struct_assembly_prop biol_id="1" type="SSA (A^2)">
         <PDBx:value>3190</PDBx:value>
      </PDBx:pdbx_struct_assembly_prop>
   </PDBx:pdbx_struct_assembly_propCategory>
   <PDBx:pdbx_struct_conn_angleCategory>
      <PDBx:pdbx_struct_conn_angle id="1">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>DG</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>1</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>N7</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>DG</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>1</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CO</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>101</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>B</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CO</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CO</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>DG</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>9</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>A</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>N7</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>DG</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id>9</PDBx:ptnr3_label_seq_id>
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>174.5</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="2">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>DG</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>1</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>N7</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>DG</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>1</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CO</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>101</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>B</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CO</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CO</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>209</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>E</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>91.1</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="3">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>DG</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>9</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>N7</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>DG</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>9</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CO</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>101</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>B</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CO</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CO</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>209</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>E</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>90.8</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="4">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>DG</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>1</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>N7</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>DG</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>1</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CO</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>101</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>B</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CO</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CO</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>204</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>E</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>92.1</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="5">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>DG</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>9</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>N7</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>DG</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>9</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CO</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>101</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>B</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CO</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CO</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>204</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>E</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>86.4</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="6">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>HOH</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>209</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>E</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>O</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>HOH</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CO</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>101</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>B</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CO</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CO</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>204</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>E</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>174.4</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="7">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>DG</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>1</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>N7</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>DG</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>1</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CO</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>101</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>B</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CO</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CO</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>211</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>E</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>91.1</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="8">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>DG</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>9</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>N7</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>DG</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>9</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CO</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>101</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>B</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CO</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CO</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>211</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>E</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>83.7</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="9">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>HOH</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>209</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>E</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>O</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>HOH</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CO</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>101</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>B</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CO</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CO</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>211</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>E</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>90.8</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="10">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>HOH</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>204</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>E</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>O</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>HOH</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CO</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>101</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>B</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CO</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CO</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>211</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>E</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>93.6</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="11">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>DG</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>1</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>N7</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>DG</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>1</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CO</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>101</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>B</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CO</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CO</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>207</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>E</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>4_665</PDBx:ptnr3_symmetry>
         <PDBx:value>92.2</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="12">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>DG</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>9</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>N7</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>DG</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>9</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CO</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>101</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>B</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CO</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CO</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>207</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>E</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>4_665</PDBx:ptnr3_symmetry>
         <PDBx:value>93.1</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="13">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>HOH</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>209</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>E</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>O</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>HOH</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CO</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>101</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>B</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CO</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CO</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>207</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>E</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>4_665</PDBx:ptnr3_symmetry>
         <PDBx:value>85.4</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="14">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>HOH</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>204</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>E</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>O</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>HOH</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CO</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>101</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>B</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CO</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CO</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>207</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>E</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>4_665</PDBx:ptnr3_symmetry>
         <PDBx:value>90.0</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="15">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>HOH</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>211</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>E</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>O</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>HOH</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CO</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>101</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>B</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CO</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CO</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>207</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>E</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>4_665</PDBx:ptnr3_symmetry>
         <PDBx:value>175.0</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="16">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>DG</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>5</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>N7</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>DG</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>5</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CO</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>102</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_alt_id>A</PDBx:ptnr2_label_alt_id>
         <PDBx:ptnr2_label_asym_id>C</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CO</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CO</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>215</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>E</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>87.4</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="17">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>DG</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>5</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>N7</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>DG</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>5</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CO</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>102</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_alt_id>A</PDBx:ptnr2_label_alt_id>
         <PDBx:ptnr2_label_asym_id>C</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CO</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CO</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>218</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>E</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>69.5</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="18">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>HOH</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>215</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>E</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>O</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>HOH</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CO</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>102</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_alt_id>A</PDBx:ptnr2_label_alt_id>
         <PDBx:ptnr2_label_asym_id>C</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CO</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CO</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>218</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>E</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>128.2</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="19">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>DG</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>5</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>N7</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>DG</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>5</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CO</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>102</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_alt_id>A</PDBx:ptnr2_label_alt_id>
         <PDBx:ptnr2_label_asym_id>C</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CO</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CO</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>223</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_alt_id>A</PDBx:ptnr3_label_alt_id>
         <PDBx:ptnr3_label_asym_id>E</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>120.6</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="20">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>HOH</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>215</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>E</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>O</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>HOH</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CO</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>102</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_alt_id>A</PDBx:ptnr2_label_alt_id>
         <PDBx:ptnr2_label_asym_id>C</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CO</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CO</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>223</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_alt_id>A</PDBx:ptnr3_label_alt_id>
         <PDBx:ptnr3_label_asym_id>E</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>81.3</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="21">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>HOH</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>218</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>E</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>O</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>HOH</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CO</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>102</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_alt_id>A</PDBx:ptnr2_label_alt_id>
         <PDBx:ptnr2_label_asym_id>C</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CO</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CO</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>223</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_alt_id>A</PDBx:ptnr3_label_alt_id>
         <PDBx:ptnr3_label_asym_id>E</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>73.0</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="22">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>DG</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>5</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>N7</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>DG</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>5</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CO</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>102</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_alt_id>B</PDBx:ptnr2_label_alt_id>
         <PDBx:ptnr2_label_asym_id>C</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CO</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CO</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>215</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>E</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>90.0</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="23">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>DG</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>5</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>N7</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>DG</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>5</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CO</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>102</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_alt_id>B</PDBx:ptnr2_label_alt_id>
         <PDBx:ptnr2_label_asym_id>C</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CO</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CO</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>218</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>E</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>82.9</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="24">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>HOH</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>215</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>E</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>O</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>HOH</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CO</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>102</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_alt_id>B</PDBx:ptnr2_label_alt_id>
         <PDBx:ptnr2_label_asym_id>C</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CO</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CO</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>218</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>E</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>160.8</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="25">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>DG</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>5</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>N7</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>DG</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>5</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CO</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>102</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_alt_id>B</PDBx:ptnr2_label_alt_id>
         <PDBx:ptnr2_label_asym_id>C</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CO</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CO</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>223</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_alt_id>B</PDBx:ptnr3_label_alt_id>
         <PDBx:ptnr3_label_asym_id>E</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>137.9</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="26">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>HOH</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>215</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>E</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>O</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>HOH</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CO</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>102</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_alt_id>B</PDBx:ptnr2_label_alt_id>
         <PDBx:ptnr2_label_asym_id>C</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CO</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CO</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>223</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_alt_id>B</PDBx:ptnr3_label_alt_id>
         <PDBx:ptnr3_label_asym_id>E</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>69.5</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="27">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>HOH</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>218</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>E</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>O</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>HOH</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CO</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>102</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_alt_id>B</PDBx:ptnr2_label_alt_id>
         <PDBx:ptnr2_label_asym_id>C</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CO</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CO</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>223</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_alt_id>B</PDBx:ptnr3_label_alt_id>
         <PDBx:ptnr3_label_asym_id>E</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>104.4</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="28">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>HOH</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>219</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>E</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>O</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>HOH</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CO</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>103</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>D</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CO</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CO</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>217</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>E</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>98.2</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="29">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>HOH</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>219</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>E</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>O</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>HOH</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CO</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>103</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>D</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CO</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CO</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>201</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_alt_id>B</PDBx:ptnr3_label_alt_id>
         <PDBx:ptnr3_label_asym_id>E</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>8_665</PDBx:ptnr3_symmetry>
         <PDBx:value>68.7</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="30">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>HOH</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>217</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>E</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>O</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>HOH</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CO</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>103</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>D</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CO</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CO</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>201</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_alt_id>B</PDBx:ptnr3_label_alt_id>
         <PDBx:ptnr3_label_asym_id>E</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>8_665</PDBx:ptnr3_symmetry>
         <PDBx:value>77.7</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="31">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>HOH</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>219</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>E</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>O</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>HOH</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CO</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>103</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>D</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CO</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CO</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>219</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>E</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>11_655</PDBx:ptnr3_symmetry>
         <PDBx:value>64.4</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="32">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>HOH</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>217</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>E</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>O</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>HOH</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CO</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>103</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>D</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CO</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CO</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>219</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>E</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>11_655</PDBx:ptnr3_symmetry>
         <PDBx:value>120.6</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="33">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>HOH</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>201</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_alt_id>B</PDBx:ptnr1_label_alt_id>
         <PDBx:ptnr1_label_asym_id>E</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>O</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>HOH</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>8_665</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CO</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>103</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>D</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CO</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CO</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>219</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>E</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>11_655</PDBx:ptnr3_symmetry>
         <PDBx:value>131.3</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
   </PDBx:pdbx_struct_conn_angleCategory>
   <PDBx:pdbx_struct_oper_listCategory>
      <PDBx:pdbx_struct_oper_list id="1">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>1.0000000000</PDBx:matrix33>
         <PDBx:name>1_555</PDBx:name>
         <PDBx:type>identity operation</PDBx:type>
         <PDBx:vector1>0.0000000000</PDBx:vector1>
         <PDBx:vector2>0.0000000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="2">
         <PDBx:matrix11>-1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>-1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>1.0000000000</PDBx:matrix33>
         <PDBx:name>4_665</PDBx:name>
         <PDBx:type>crystal symmetry operation</PDBx:type>
         <PDBx:vector1>17.3200000000</PDBx:vector1>
         <PDBx:vector2>29.9991199871</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
   </PDBx:pdbx_struct_oper_listCategory>
   <PDBx:pdbx_struct_special_symmetryCategory>
      <PDBx:pdbx_struct_special_symmetry id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>CO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>103</PDBx:auth_seq_id>
         <PDBx:label_asym_id>D</PDBx:label_asym_id>
         <PDBx:label_comp_id>CO</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
      </PDBx:pdbx_struct_special_symmetry>
      <PDBx:pdbx_struct_special_symmetry id="2">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>224</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
      </PDBx:pdbx_struct_special_symmetry>
   </PDBx:pdbx_struct_special_symmetryCategory>
   <PDBx:pdbx_validate_close_contactCategory>
      <PDBx:pdbx_validate_close_contact id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CO</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>CO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>102</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>202</PDBx:auth_seq_id_2>
         <PDBx:dist>1.64</PDBx:dist>
         <PDBx:label_alt_id_1>A</PDBx:label_alt_id_1>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="2">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CO</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>CO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>102</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>203</PDBx:auth_seq_id_2>
         <PDBx:dist>1.65</PDBx:dist>
         <PDBx:label_alt_id_1>B</PDBx:label_alt_id_1>
      </PDBx:pdbx_validate_close_contact>
   </PDBx:pdbx_validate_close_contactCategory>
   <PDBx:pdbx_versionCategory>
      <PDBx:pdbx_version entry_id="4ZKK" major_version="4" minor_version="0000" revision_type="Initial release">
         <PDBx:details>Initial release</PDBx:details>
         <PDBx:revision_date>2015-10-14</PDBx:revision_date>
      </PDBx:pdbx_version>
      <PDBx:pdbx_version entry_id="4ZKK" major_version="4" minor_version="0001" revision_type="Citation">
         <PDBx:details>Citation</PDBx:details>
         <PDBx:revision_date>2016-01-20</PDBx:revision_date>
      </PDBx:pdbx_version>
   </PDBx:pdbx_versionCategory>
   <PDBx:refineCategory>
      <PDBx:refine entry_id="4ZKK" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:ls_R_factor_R_free>0.2463</PDBx:ls_R_factor_R_free>
         <PDBx:ls_R_factor_R_work>0.2291</PDBx:ls_R_factor_R_work>
         <PDBx:ls_R_factor_obs>0.2309</PDBx:ls_R_factor_obs>
         <PDBx:ls_d_res_high>1.801</PDBx:ls_d_res_high>
         <PDBx:ls_d_res_low>24.927</PDBx:ls_d_res_low>
         <PDBx:ls_number_reflns_R_free>541</PDBx:ls_number_reflns_R_free>
         <PDBx:ls_number_reflns_obs>5358</PDBx:ls_number_reflns_obs>
         <PDBx:ls_percent_reflns_R_free>10.10</PDBx:ls_percent_reflns_R_free>
         <PDBx:ls_percent_reflns_obs>95.88</PDBx:ls_percent_reflns_obs>
         <PDBx:overall_SU_ML>0.21</PDBx:overall_SU_ML>
         <PDBx:pdbx_R_Free_selection_details>Random selection</PDBx:pdbx_R_Free_selection_details>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_ls_cross_valid_method>FREE R-VALUE</PDBx:pdbx_ls_cross_valid_method>
         <PDBx:pdbx_ls_sigma_F>0.00</PDBx:pdbx_ls_sigma_F>
         <PDBx:pdbx_method_to_determine_struct>SAD</PDBx:pdbx_method_to_determine_struct>
         <PDBx:pdbx_overall_phase_error>0.31</PDBx:pdbx_overall_phase_error>
         <PDBx:pdbx_solvent_shrinkage_radii>0.90</PDBx:pdbx_solvent_shrinkage_radii>
         <PDBx:pdbx_solvent_vdw_probe_radii>1.11</PDBx:pdbx_solvent_vdw_probe_radii>
         <PDBx:pdbx_stereochemistry_target_values>MLHL</PDBx:pdbx_stereochemistry_target_values>
         <PDBx:solvent_model_details>FLAT BULK SOLVENT MODEL</PDBx:solvent_model_details>
      </PDBx:refine>
   </PDBx:refineCategory>
   <PDBx:refine_histCategory>
      <PDBx:refine_hist cycle_id="LAST" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:d_res_high>1.801</PDBx:d_res_high>
         <PDBx:d_res_low>24.927</PDBx:d_res_low>
         <PDBx:number_atoms_solvent>24</PDBx:number_atoms_solvent>
         <PDBx:number_atoms_total>229</PDBx:number_atoms_total>
         <PDBx:pdbx_number_atoms_ligand>3</PDBx:pdbx_number_atoms_ligand>
         <PDBx:pdbx_number_atoms_nucleic_acid>202</PDBx:pdbx_number_atoms_nucleic_acid>
         <PDBx:pdbx_number_atoms_protein>0</PDBx:pdbx_number_atoms_protein>
      </PDBx:refine_hist>
   </PDBx:refine_histCategory>
   <PDBx:refine_ls_restrCategory>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="f_bond_d">
         <PDBx:dev_ideal>0.004</PDBx:dev_ideal>
         <PDBx:number>226</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="f_angle_d">
         <PDBx:dev_ideal>0.557</PDBx:dev_ideal>
         <PDBx:number>347</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="f_dihedral_angle_d">
         <PDBx:dev_ideal>32.259</PDBx:dev_ideal>
         <PDBx:number>96</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="f_chiral_restr">
         <PDBx:dev_ideal>0.024</PDBx:dev_ideal>
         <PDBx:number>39</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="f_plane_restr">
         <PDBx:dev_ideal>0.002</PDBx:dev_ideal>
         <PDBx:number>10</PDBx:number>
      </PDBx:refine_ls_restr>
   </PDBx:refine_ls_restrCategory>
   <PDBx:refine_ls_shellCategory>
      <PDBx:refine_ls_shell d_res_high="1.8006" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.2940</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_free_error xsi:nil="true" />
         <PDBx:R_factor_R_work>0.2809</PDBx:R_factor_R_work>
         <PDBx:R_factor_all xsi:nil="true" />
         <PDBx:R_factor_obs xsi:nil="true" />
         <PDBx:d_res_low>1.9817</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>124</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>1079</PDBx:number_reflns_R_work>
         <PDBx:number_reflns_all xsi:nil="true" />
         <PDBx:number_reflns_obs xsi:nil="true" />
         <PDBx:pdbx_fsc_free xsi:nil="true" />
         <PDBx:pdbx_fsc_work xsi:nil="true" />
         <PDBx:pdbx_phase_error xsi:nil="true" />
         <PDBx:pdbx_total_number_of_bins_used xsi:nil="true" />
         <PDBx:percent_reflns_R_free xsi:nil="true" />
         <PDBx:percent_reflns_obs>87.00</PDBx:percent_reflns_obs>
         <PDBx:redundancy_reflns_all xsi:nil="true" />
         <PDBx:redundancy_reflns_obs xsi:nil="true" />
         <PDBx:wR_factor_R_free xsi:nil="true" />
         <PDBx:wR_factor_R_work xsi:nil="true" />
         <PDBx:wR_factor_all xsi:nil="true" />
         <PDBx:wR_factor_obs xsi:nil="true" />
      </PDBx:refine_ls_shell>
      <PDBx:refine_ls_shell d_res_high="1.9817" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.3283</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_free_error xsi:nil="true" />
         <PDBx:R_factor_R_work>0.2766</PDBx:R_factor_R_work>
         <PDBx:R_factor_all xsi:nil="true" />
         <PDBx:R_factor_obs xsi:nil="true" />
         <PDBx:d_res_low>2.2683</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>138</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>1227</PDBx:number_reflns_R_work>
         <PDBx:number_reflns_all xsi:nil="true" />
         <PDBx:number_reflns_obs xsi:nil="true" />
         <PDBx:pdbx_fsc_free xsi:nil="true" />
         <PDBx:pdbx_fsc_work xsi:nil="true" />
         <PDBx:pdbx_phase_error xsi:nil="true" />
         <PDBx:pdbx_total_number_of_bins_used xsi:nil="true" />
         <PDBx:percent_reflns_R_free xsi:nil="true" />
         <PDBx:percent_reflns_obs>98.00</PDBx:percent_reflns_obs>
         <PDBx:redundancy_reflns_all xsi:nil="true" />
         <PDBx:redundancy_reflns_obs xsi:nil="true" />
         <PDBx:wR_factor_R_free xsi:nil="true" />
         <PDBx:wR_factor_R_work xsi:nil="true" />
         <PDBx:wR_factor_all xsi:nil="true" />
         <PDBx:wR_factor_obs xsi:nil="true" />
      </PDBx:refine_ls_shell>
      <PDBx:refine_ls_shell d_res_high="2.2683" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.2780</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_free_error xsi:nil="true" />
         <PDBx:R_factor_R_work>0.2697</PDBx:R_factor_R_work>
         <PDBx:R_factor_all xsi:nil="true" />
         <PDBx:R_factor_obs xsi:nil="true" />
         <PDBx:d_res_low>2.8572</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>139</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>1254</PDBx:number_reflns_R_work>
         <PDBx:number_reflns_all xsi:nil="true" />
         <PDBx:number_reflns_obs xsi:nil="true" />
         <PDBx:pdbx_fsc_free xsi:nil="true" />
         <PDBx:pdbx_fsc_work xsi:nil="true" />
         <PDBx:pdbx_phase_error xsi:nil="true" />
         <PDBx:pdbx_total_number_of_bins_used xsi:nil="true" />
         <PDBx:percent_reflns_R_free xsi:nil="true" />
         <PDBx:percent_reflns_obs>99.00</PDBx:percent_reflns_obs>
         <PDBx:redundancy_reflns_all xsi:nil="true" />
         <PDBx:redundancy_reflns_obs xsi:nil="true" />
         <PDBx:wR_factor_R_free xsi:nil="true" />
         <PDBx:wR_factor_R_work xsi:nil="true" />
         <PDBx:wR_factor_all xsi:nil="true" />
         <PDBx:wR_factor_obs xsi:nil="true" />
      </PDBx:refine_ls_shell>
      <PDBx:refine_ls_shell d_res_high="2.8572" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.2200</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_free_error xsi:nil="true" />
         <PDBx:R_factor_R_work>0.2015</PDBx:R_factor_R_work>
         <PDBx:R_factor_all xsi:nil="true" />
         <PDBx:R_factor_obs xsi:nil="true" />
         <PDBx:d_res_low>24.9292</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>140</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>1257</PDBx:number_reflns_R_work>
         <PDBx:number_reflns_all xsi:nil="true" />
         <PDBx:number_reflns_obs xsi:nil="true" />
         <PDBx:pdbx_fsc_free xsi:nil="true" />
         <PDBx:pdbx_fsc_work xsi:nil="true" />
         <PDBx:pdbx_phase_error xsi:nil="true" />
         <PDBx:pdbx_total_number_of_bins_used xsi:nil="true" />
         <PDBx:percent_reflns_R_free xsi:nil="true" />
         <PDBx:percent_reflns_obs>100.00</PDBx:percent_reflns_obs>
         <PDBx:redundancy_reflns_all xsi:nil="true" />
         <PDBx:redundancy_reflns_obs xsi:nil="true" />
         <PDBx:wR_factor_R_free xsi:nil="true" />
         <PDBx:wR_factor_R_work xsi:nil="true" />
         <PDBx:wR_factor_all xsi:nil="true" />
         <PDBx:wR_factor_obs xsi:nil="true" />
      </PDBx:refine_ls_shell>
   </PDBx:refine_ls_shellCategory>
   <PDBx:reflnsCategory>
      <PDBx:reflns pdbx_ordinal="1">
         <PDBx:d_resolution_high>1.80</PDBx:d_resolution_high>
         <PDBx:d_resolution_low>30.0</PDBx:d_resolution_low>
         <PDBx:entry_id>4ZKK</PDBx:entry_id>
         <PDBx:number_obs>5358</PDBx:number_obs>
         <PDBx:pdbx_Rmerge_I_obs>0.09</PDBx:pdbx_Rmerge_I_obs>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_netI_over_sigmaI>36.6</PDBx:pdbx_netI_over_sigmaI>
         <PDBx:pdbx_redundancy>32</PDBx:pdbx_redundancy>
         <PDBx:percent_possible_obs>98</PDBx:percent_possible_obs>
      </PDBx:reflns>
   </PDBx:reflnsCategory>
   <PDBx:reflns_shellCategory>
      <PDBx:reflns_shell pdbx_ordinal="1">
         <PDBx:Rmerge_I_obs>0.66</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>1.80</PDBx:d_res_high>
         <PDBx:d_res_low>1.86</PDBx:d_res_low>
         <PDBx:meanI_over_sigI_obs>3.8</PDBx:meanI_over_sigI_obs>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>14.4</PDBx:pdbx_redundancy>
         <PDBx:percent_possible_all>83.7</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
   </PDBx:reflns_shellCategory>
   <PDBx:softwareCategory>
      <PDBx:software pdbx_ordinal="1">
         <PDBx:classification>refinement</PDBx:classification>
         <PDBx:name>PHENIX</PDBx:name>
         <PDBx:version>1.9_1692</PDBx:version>
      </PDBx:software>
      <PDBx:software pdbx_ordinal="2">
         <PDBx:classification>data collection</PDBx:classification>
         <PDBx:name>MxCuBE</PDBx:name>
         <PDBx:version>2.0</PDBx:version>
      </PDBx:software>
      <PDBx:software pdbx_ordinal="3">
         <PDBx:classification>data processing</PDBx:classification>
         <PDBx:name>MOSFLM</PDBx:name>
         <PDBx:version>7.0.9</PDBx:version>
      </PDBx:software>
      <PDBx:software pdbx_ordinal="4">
         <PDBx:classification>phasing</PDBx:classification>
         <PDBx:name>PHENIX</PDBx:name>
         <PDBx:version>1.9_1692</PDBx:version>
      </PDBx:software>
      <PDBx:software pdbx_ordinal="5">
         <PDBx:classification>data reduction</PDBx:classification>
         <PDBx:name>MOSFLM</PDBx:name>
         <PDBx:version>7.0.9</PDBx:version>
      </PDBx:software>
      <PDBx:software pdbx_ordinal="6">
         <PDBx:classification>data scaling</PDBx:classification>
         <PDBx:name>Aimless</PDBx:name>
         <PDBx:version>0.2.14</PDBx:version>
      </PDBx:software>
   </PDBx:softwareCategory>
   <PDBx:structCategory>
      <PDBx:struct entry_id="4ZKK">
         <PDBx:pdbx_descriptor>DNA (5&apos;-D(*GP*CP*AP*TP*GP*CP*AP*TP*GP*C)-3&apos;)</PDBx:pdbx_descriptor>
         <PDBx:title>The novel double-fold structure of d(GCATGCATGC)</PDBx:title>
      </PDBx:struct>
   </PDBx:structCategory>
   <PDBx:struct_asymCategory>
      <PDBx:struct_asym id="A">
         <PDBx:entity_id>1</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="B">
         <PDBx:entity_id>2</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="C">
         <PDBx:entity_id>2</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="D">
         <PDBx:entity_id>2</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="E">
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
   </PDBx:struct_asymCategory>
   <PDBx:struct_connCategory>
      <PDBx:struct_conn id="metalc1">
         <PDBx:conn_type_id>metalc</PDBx:conn_type_id>
         <PDBx:pdbx_dist_value>2.194</PDBx:pdbx_dist_value>
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>DG</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>1</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>N7</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>DG</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>1</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CO</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>101</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>B</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CO</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CO</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
      <PDBx:struct_conn id="metalc2">
         <PDBx:conn_type_id>metalc</PDBx:conn_type_id>
         <PDBx:pdbx_dist_value>2.433</PDBx:pdbx_dist_value>
         <PDBx:pdbx_ptnr2_label_alt_id>A</PDBx:pdbx_ptnr2_label_alt_id>
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>DG</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>5</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>N7</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>DG</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>5</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CO</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>102</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>C</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CO</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CO</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
      <PDBx:struct_conn id="metalc3">
         <PDBx:conn_type_id>metalc</PDBx:conn_type_id>
         <PDBx:pdbx_dist_value>2.249</PDBx:pdbx_dist_value>
         <PDBx:pdbx_ptnr2_label_alt_id>B</PDBx:pdbx_ptnr2_label_alt_id>
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>DG</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>5</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>N7</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>DG</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>5</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CO</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>102</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>C</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CO</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CO</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
      <PDBx:struct_conn id="metalc4">
         <PDBx:conn_type_id>metalc</PDBx:conn_type_id>
         <PDBx:pdbx_dist_value>2.271</PDBx:pdbx_dist_value>
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>DG</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>9</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>N7</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>DG</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>9</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CO</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>101</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>B</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CO</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CO</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
      <PDBx:struct_conn id="metalc5">
         <PDBx:conn_type_id>metalc</PDBx:conn_type_id>
         <PDBx:pdbx_dist_value>2.041</PDBx:pdbx_dist_value>
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CO</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>101</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>B</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>CO</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CO</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>HOH</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>209</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>E</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>O</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>HOH</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
      <PDBx:struct_conn id="metalc6">
         <PDBx:conn_type_id>metalc</PDBx:conn_type_id>
         <PDBx:pdbx_dist_value>2.099</PDBx:pdbx_dist_value>
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CO</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>101</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>B</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>CO</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CO</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>HOH</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>204</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>E</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>O</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>HOH</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
      <PDBx:struct_conn id="metalc7">
         <PDBx:conn_type_id>metalc</PDBx:conn_type_id>
         <PDBx:pdbx_dist_value>2.285</PDBx:pdbx_dist_value>
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CO</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>101</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>B</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>CO</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CO</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>HOH</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>211</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>E</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>O</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>HOH</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
      <PDBx:struct_conn id="metalc8">
         <PDBx:conn_type_id>metalc</PDBx:conn_type_id>
         <PDBx:pdbx_dist_value>2.281</PDBx:pdbx_dist_value>
         <PDBx:pdbx_ptnr1_label_alt_id>A</PDBx:pdbx_ptnr1_label_alt_id>
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CO</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>102</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>C</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>CO</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CO</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>HOH</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>215</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>E</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>O</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>HOH</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
      <PDBx:struct_conn id="metalc9">
         <PDBx:conn_type_id>metalc</PDBx:conn_type_id>
         <PDBx:pdbx_dist_value>2.777</PDBx:pdbx_dist_value>
         <PDBx:pdbx_ptnr1_label_alt_id>A</PDBx:pdbx_ptnr1_label_alt_id>
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CO</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>102</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>C</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>CO</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CO</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>HOH</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>218</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>E</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>O</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>HOH</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
      <PDBx:struct_conn id="metalc10">
         <PDBx:conn_type_id>metalc</PDBx:conn_type_id>
         <PDBx:pdbx_dist_value>2.398</PDBx:pdbx_dist_value>
         <PDBx:pdbx_ptnr1_label_alt_id>A</PDBx:pdbx_ptnr1_label_alt_id>
         <PDBx:pdbx_ptnr2_label_alt_id>A</PDBx:pdbx_ptnr2_label_alt_id>
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CO</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>102</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>C</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>CO</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CO</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>HOH</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>223</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>E</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>O</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>HOH</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
      <PDBx:struct_conn id="metalc11">
         <PDBx:conn_type_id>metalc</PDBx:conn_type_id>
         <PDBx:pdbx_dist_value>2.360</PDBx:pdbx_dist_value>
         <PDBx:pdbx_ptnr1_label_alt_id>B</PDBx:pdbx_ptnr1_label_alt_id>
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CO</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>102</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>C</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>CO</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CO</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>HOH</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>215</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>E</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>O</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>HOH</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
      <PDBx:struct_conn id="metalc12">
         <PDBx:conn_type_id>metalc</PDBx:conn_type_id>
         <PDBx:pdbx_dist_value>2.260</PDBx:pdbx_dist_value>
         <PDBx:pdbx_ptnr1_label_alt_id>B</PDBx:pdbx_ptnr1_label_alt_id>
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CO</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>102</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>C</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>CO</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CO</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>HOH</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>218</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>E</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>O</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>HOH</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
      <PDBx:struct_conn id="metalc13">
         <PDBx:conn_type_id>metalc</PDBx:conn_type_id>
         <PDBx:pdbx_dist_value>2.491</PDBx:pdbx_dist_value>
         <PDBx:pdbx_ptnr1_label_alt_id>B</PDBx:pdbx_ptnr1_label_alt_id>
         <PDBx:pdbx_ptnr2_label_alt_id>B</PDBx:pdbx_ptnr2_label_alt_id>
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CO</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>102</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>C</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>CO</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CO</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>HOH</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>223</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>E</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>O</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>HOH</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
      <PDBx:struct_conn id="metalc14">
         <PDBx:conn_type_id>metalc</PDBx:conn_type_id>
         <PDBx:pdbx_dist_value>2.509</PDBx:pdbx_dist_value>
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CO</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>103</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>D</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>CO</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CO</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>HOH</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>219</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>E</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>O</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>HOH</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
      <PDBx:struct_conn id="metalc15">
         <PDBx:conn_type_id>metalc</PDBx:conn_type_id>
         <PDBx:pdbx_dist_value>1.728</PDBx:pdbx_dist_value>
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CO</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>103</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>D</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>CO</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CO</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>HOH</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>217</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>E</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>O</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>HOH</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
      <PDBx:struct_conn id="metalc16">
         <PDBx:conn_type_id>metalc</PDBx:conn_type_id>
         <PDBx:pdbx_dist_value>2.328</PDBx:pdbx_dist_value>
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CO</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>101</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>B</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>CO</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CO</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>HOH</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>207</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>E</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>O</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>HOH</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>4_665</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
      <PDBx:struct_conn id="metalc17">
         <PDBx:conn_type_id>metalc</PDBx:conn_type_id>
         <PDBx:pdbx_dist_value>2.283</PDBx:pdbx_dist_value>
         <PDBx:pdbx_ptnr2_label_alt_id>B</PDBx:pdbx_ptnr2_label_alt_id>
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CO</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>103</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>D</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>CO</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CO</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>HOH</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>201</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>E</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>O</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>HOH</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>8_665</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
      <PDBx:struct_conn id="metalc18">
         <PDBx:conn_type_id>metalc</PDBx:conn_type_id>
         <PDBx:pdbx_dist_value>2.567</PDBx:pdbx_dist_value>
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CO</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>103</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>D</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>CO</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CO</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>HOH</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>219</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>E</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>O</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>HOH</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>11_655</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
      <PDBx:struct_conn id="hydrog1">
         <PDBx:conn_type_id>hydrog</PDBx:conn_type_id>
         <PDBx:details>DG-DC PAIR</PDBx:details>
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>DG</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>1</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>N2</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>DG</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>1</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>DC</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>6</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>A</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>O2</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>DC</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id>6</PDBx:ptnr2_label_seq_id>
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
      <PDBx:struct_conn id="hydrog2">
         <PDBx:conn_type_id>hydrog</PDBx:conn_type_id>
         <PDBx:details>DC-DG PAIR</PDBx:details>
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>DC</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>2</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>O2</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>DC</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>2</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>DG</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>5</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>A</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>N2</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>DG</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id>5</PDBx:ptnr2_label_seq_id>
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
   </PDBx:struct_connCategory>
   <PDBx:struct_conn_typeCategory>
      <PDBx:struct_conn_type id="metalc">
      </PDBx:struct_conn_type>
      <PDBx:struct_conn_type id="hydrog">
      </PDBx:struct_conn_type>
   </PDBx:struct_conn_typeCategory>
   <PDBx:struct_keywordsCategory>
      <PDBx:struct_keywords entry_id="4ZKK">
         <PDBx:pdbx_keywords>DNA</PDBx:pdbx_keywords>
         <PDBx:text>folded, minor-groove tetrad, bi-loop, triplet, DNA</PDBx:text>
      </PDBx:struct_keywords>
   </PDBx:struct_keywordsCategory>
   <PDBx:struct_refCategory>
      <PDBx:struct_ref id="1">
         <PDBx:db_code>4ZKK</PDBx:db_code>
         <PDBx:db_name>PDB</PDBx:db_name>
         <PDBx:entity_id>1</PDBx:entity_id>
         <PDBx:pdbx_align_begin>1</PDBx:pdbx_align_begin>
         <PDBx:pdbx_db_accession>4ZKK</PDBx:pdbx_db_accession>
      </PDBx:struct_ref>
   </PDBx:struct_refCategory>
   <PDBx:struct_ref_seqCategory>
      <PDBx:struct_ref_seq align_id="1">
         <PDBx:db_align_beg>1</PDBx:db_align_beg>
         <PDBx:db_align_end>10</PDBx:db_align_end>
         <PDBx:pdbx_PDB_id_code>4ZKK</PDBx:pdbx_PDB_id_code>
         <PDBx:pdbx_auth_seq_align_beg>1</PDBx:pdbx_auth_seq_align_beg>
         <PDBx:pdbx_auth_seq_align_end>10</PDBx:pdbx_auth_seq_align_end>
         <PDBx:pdbx_db_accession>4ZKK</PDBx:pdbx_db_accession>
         <PDBx:pdbx_strand_id>A</PDBx:pdbx_strand_id>
         <PDBx:ref_id>1</PDBx:ref_id>
         <PDBx:seq_align_beg>1</PDBx:seq_align_beg>
         <PDBx:seq_align_end>10</PDBx:seq_align_end>
      </PDBx:struct_ref_seq>
   </PDBx:struct_ref_seqCategory>
   <PDBx:struct_siteCategory>
      <PDBx:struct_site id="AC1">
         <PDBx:details>binding site for residue CO A 101</PDBx:details>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_comp_id>CO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>101</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_evidence_code>Software</PDBx:pdbx_evidence_code>
         <PDBx:pdbx_num_residues>6</PDBx:pdbx_num_residues>
      </PDBx:struct_site>
      <PDBx:struct_site id="AC2">
         <PDBx:details>binding site for residue CO A 102</PDBx:details>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_comp_id>CO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>102</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_evidence_code>Software</PDBx:pdbx_evidence_code>
         <PDBx:pdbx_num_residues>7</PDBx:pdbx_num_residues>
      </PDBx:struct_site>
      <PDBx:struct_site id="AC3">
         <PDBx:details>binding site for residue CO A 103</PDBx:details>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_comp_id>CO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>103</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_evidence_code>Software</PDBx:pdbx_evidence_code>
         <PDBx:pdbx_num_residues>6</PDBx:pdbx_num_residues>
      </PDBx:struct_site>
   </PDBx:struct_siteCategory>
   <PDBx:struct_site_genCategory>
      <PDBx:struct_site_gen id="1" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>DG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>1</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>DG</PDBx:label_comp_id>
         <PDBx:label_seq_id>1</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>6</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="2" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>DG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>9</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>DG</PDBx:label_comp_id>
         <PDBx:label_seq_id>9</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>6</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="3" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>204</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>6</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="4" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>207</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>6</PDBx:pdbx_num_res>
         <PDBx:symmetry>4_665</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="5" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>209</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>6</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="6" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>211</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>6</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="7" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>DG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>5</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>DG</PDBx:label_comp_id>
         <PDBx:label_seq_id>5</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>7</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="8" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>DC</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>6</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>DC</PDBx:label_comp_id>
         <PDBx:label_seq_id>6</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>7</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="9" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>202</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>7</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="10" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>203</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>7</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="11" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>215</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>7</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="12" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>218</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>7</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="13" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>223</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>7</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="14" site_id="AC3">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>201</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>6</PDBx:pdbx_num_res>
         <PDBx:symmetry>8_665</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="15" site_id="AC3">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>201</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>6</PDBx:pdbx_num_res>
         <PDBx:symmetry>4_665</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="16" site_id="AC3">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>217</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>6</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="17" site_id="AC3">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>217</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>6</PDBx:pdbx_num_res>
         <PDBx:symmetry>11_655</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="18" site_id="AC3">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>219</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>6</PDBx:pdbx_num_res>
         <PDBx:symmetry>11_655</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="19" site_id="AC3">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>219</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>6</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
   </PDBx:struct_site_genCategory>
   <PDBx:symmetryCategory>
      <PDBx:symmetry entry_id="4ZKK">
         <PDBx:Int_Tables_number>180</PDBx:Int_Tables_number>
         <PDBx:space_group_name_H-M>P 62 2 2</PDBx:space_group_name_H-M>
      </PDBx:symmetry>
   </PDBx:symmetryCategory>
</PDBx:datablock>
