data_5HBW
# 
_entry.id   5HBW 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    4.069 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
PDB   5HBW         
WWPDB D_1000216797 
# 
loop_
_database_PDB_rev.num 
_database_PDB_rev.date 
_database_PDB_rev.date_original 
_database_PDB_rev.status 
_database_PDB_rev.replaces 
_database_PDB_rev.mod_type 
1 2016-12-07 2016-01-03 ? 5HBW 0 
2 2017-01-18 ?          ? 5HBW 1 
# 
_database_PDB_rev_record.rev_num   2 
_database_PDB_rev_record.type      JRNL 
_database_PDB_rev_record.details   ? 
# 
_pdbx_database_status.status_code                      REL 
_pdbx_database_status.status_code_sf                   REL 
_pdbx_database_status.status_code_mr                   ? 
_pdbx_database_status.entry_id                         5HBW 
_pdbx_database_status.date_begin_release_preparation   . 
_pdbx_database_status.SG_entry                         N 
_pdbx_database_status.deposit_site                     RCSB 
_pdbx_database_status.process_site                     RCSB 
_pdbx_database_status.methods_development_category     ? 
_pdbx_database_status.pdb_format_compatible            Y 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
'Zhang, W.'     1 
'Tam, C.P.'     2 
'Szostak, J.W.' 3 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'ACS Cent Sci' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2374-7943 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            2 
_citation.language                  ? 
_citation.page_first                916 
_citation.page_last                 926 
_citation.title                     'Unusual Base-Pairing Interactions in Monomer-Template Complexes.' 
_citation.year                      2016 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1021/acscentsci.6b00278 
_citation.pdbx_database_id_PubMed   28058281 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
primary 'Zhang, W.'     1 
primary 'Tam, C.P.'     2 
primary 'Wang, J.'      3 
primary 'Szostak, J.W.' 4 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     5HBW 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     28.076 
_cell.length_a_esd                 ? 
_cell.length_b                     39.747 
_cell.length_b_esd                 ? 
_cell.length_c                     42.593 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
# 
_symmetry.entry_id                         5HBW 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     syn 
;RNA (5'-R(*(LCC)P*(TLN)P*(LCG)P*UP*AP*CP*A)-3')
;
2245.440 2 ? ? ? ? 
2 non-polymer syn 
;[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-(3-methyl-1~{H}-pyrazol-4-yl)phosphinic acid
;
427.309  2 ? ? ? ? 
3 water       nat water 18.015   3 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           polyribonucleotide 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   yes 
_entity_poly.pdbx_seq_one_letter_code       '(LCC)(TLN)(LCG)UACA' 
_entity_poly.pdbx_seq_one_letter_code_can   NUGUACA 
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1 LCC n 
1 2 TLN n 
1 3 LCG n 
1 4 U   n 
1 5 A   n 
1 6 C   n 
1 7 A   n 
# 
_pdbx_entity_src_syn.entity_id              1 
_pdbx_entity_src_syn.pdbx_src_id            1 
_pdbx_entity_src_syn.pdbx_alt_source_flag   sample 
_pdbx_entity_src_syn.pdbx_beg_seq_num       1 
_pdbx_entity_src_syn.pdbx_end_seq_num       7 
_pdbx_entity_src_syn.organism_scientific    'synthetic construct' 
_pdbx_entity_src_syn.organism_common_name   ? 
_pdbx_entity_src_syn.ncbi_taxonomy_id       32630 
_pdbx_entity_src_syn.details                ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    PDB 
_struct_ref.db_code                    5HBW 
_struct_ref.pdbx_db_accession          5HBW 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   ? 
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 5HBW A 1 ? 7 ? 5HBW 1 ? 7 ? 1 7 
2 1 5HBW B 1 ? 7 ? 5HBW 1 ? 7 ? 1 7 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A   'RNA linking' y "ADENOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O7 P' 347.221 
C   'RNA linking' y "CYTIDINE-5'-MONOPHOSPHATE" ? 'C9 H14 N3 O8 P'  323.197 
HOH non-polymer   . WATER ? 'H2 O'            18.015  
LCC 'RNA linking' . 
'[(1R,3R,4R,7S)-7-HYDROXY-3-(5-METHYLCYTOSIN-1-YL)-2,5-DIOXABICYCLO[2.2.1]HEPT-1-YL]METHYL DIHYDROGEN PHOSPHATE' ? 
'C11 H16 N3 O8 P' 349.234 
LCG 'RNA linking' n '[(1R,3R,4R,7S)-7-HYDROXY-3-(GUANIN-9-YL)-2,5-DIOXABICYCLO[2.2.1]HEPT-1-YL]METHYL DIHYDROGEN PHOSPHATE' ? 
'C11 H14 N5 O8 P' 375.231 
PZG 'DNA linking' n 
;[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-(3-methyl-1~{H}-pyrazol-4-yl)phosphinic acid
;
? 'C14 H18 N7 O7 P' 427.309 
TLN 'RNA linking' n '[(1R,3R,4R,7S)-7-HYDROXY-3-(THYMIN-1-YL)-2,5-DIOXABICYCLO[2.2.1]HEPT-1-YL]METHYL DIHYDROGEN PHOSPHATE' ? 
'C11 H15 N2 O9 P' 350.219 
U   'RNA linking' y "URIDINE-5'-MONOPHOSPHATE" ? 'C9 H13 N2 O9 P'  324.181 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   5HBW 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                      ? 
_exptl_crystal.density_diffrn              ? 
_exptl_crystal.density_Matthews            2.65 
_exptl_crystal.density_method              ? 
_exptl_crystal.density_percent_sol         53.51 
_exptl_crystal.description                 needle 
_exptl_crystal.F_000                       ? 
_exptl_crystal.id                          1 
_exptl_crystal.preparation                 ? 
_exptl_crystal.size_max                    ? 
_exptl_crystal.size_mid                    ? 
_exptl_crystal.size_min                    ? 
_exptl_crystal.size_rad                    ? 
_exptl_crystal.colour_lustre               ? 
_exptl_crystal.colour_modifier             ? 
_exptl_crystal.colour_primary              ? 
_exptl_crystal.density_meas                ? 
_exptl_crystal.density_meas_esd            ? 
_exptl_crystal.density_meas_gt             ? 
_exptl_crystal.density_meas_lt             ? 
_exptl_crystal.density_meas_temp           ? 
_exptl_crystal.density_meas_temp_esd       ? 
_exptl_crystal.density_meas_temp_gt        ? 
_exptl_crystal.density_meas_temp_lt        ? 
_exptl_crystal.pdbx_crystal_image_url      ? 
_exptl_crystal.pdbx_crystal_image_format   ? 
_exptl_crystal.pdbx_mosaicity              ? 
_exptl_crystal.pdbx_mosaicity_esd          ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7.0 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp            292 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    
;(+/-)-2-Methyl-2,4-pentanediol, Sodium cacodylate trihydrate, Spermine tetrahydrochloride, Sodium chloride, Potassium chloride, Magnesium chloride hexahydrate
;
_exptl_crystal_grow.pdbx_pH_range   ? 
# 
_diffrn.ambient_environment    ? 
_diffrn.ambient_temp           100 
_diffrn.ambient_temp_details   ? 
_diffrn.ambient_temp_esd       ? 
_diffrn.crystal_id             1 
_diffrn.crystal_support        ? 
_diffrn.crystal_treatment      ? 
_diffrn.details                ? 
_diffrn.id                     1 
_diffrn.ambient_pressure       ? 
_diffrn.ambient_pressure_esd   ? 
_diffrn.ambient_pressure_gt    ? 
_diffrn.ambient_pressure_lt    ? 
_diffrn.ambient_temp_gt        ? 
_diffrn.ambient_temp_lt        ? 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     CCD 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'MAR CCD 165 mm' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2015-10-18 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    none 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.987 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'ALS BEAMLINE 8.2.1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.987 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   8.2.1 
_diffrn_source.pdbx_synchrotron_site       ALS 
# 
_reflns.B_iso_Wilson_estimate            ? 
_reflns.entry_id                         5HBW 
_reflns.data_reduction_details           ? 
_reflns.data_reduction_method            ? 
_reflns.d_resolution_high                1.9 
_reflns.d_resolution_low                 50 
_reflns.details                          ? 
_reflns.limit_h_max                      ? 
_reflns.limit_h_min                      ? 
_reflns.limit_k_max                      ? 
_reflns.limit_k_min                      ? 
_reflns.limit_l_max                      ? 
_reflns.limit_l_min                      ? 
_reflns.number_all                       4036 
_reflns.number_obs                       4036 
_reflns.observed_criterion               ? 
_reflns.observed_criterion_F_max         ? 
_reflns.observed_criterion_F_min         ? 
_reflns.observed_criterion_I_max         ? 
_reflns.observed_criterion_I_min         ? 
_reflns.observed_criterion_sigma_F       0.05 
_reflns.observed_criterion_sigma_I       0.05 
_reflns.percent_possible_obs             99.7 
_reflns.R_free_details                   ? 
_reflns.Rmerge_F_all                     ? 
_reflns.Rmerge_F_obs                     ? 
_reflns.Friedel_coverage                 ? 
_reflns.number_gt                        ? 
_reflns.threshold_expression             ? 
_reflns.pdbx_redundancy                  6.1 
_reflns.pdbx_Rmerge_I_obs                0.053 
_reflns.pdbx_Rmerge_I_all                ? 
_reflns.pdbx_Rsym_value                  ? 
_reflns.pdbx_netI_over_av_sigmaI         24.8 
_reflns.pdbx_netI_over_sigmaI            24.8 
_reflns.pdbx_res_netI_over_av_sigmaI_2   ? 
_reflns.pdbx_res_netI_over_sigmaI_2      ? 
_reflns.pdbx_chi_squared                 ? 
_reflns.pdbx_scaling_rejects             ? 
_reflns.pdbx_d_res_high_opt              ? 
_reflns.pdbx_d_res_low_opt               ? 
_reflns.pdbx_d_res_opt_method            ? 
_reflns.phase_calculation_details        ? 
_reflns.pdbx_Rrim_I_all                  ? 
_reflns.pdbx_Rpim_I_all                  ? 
_reflns.pdbx_d_opt                       ? 
_reflns.pdbx_number_measured_all         ? 
_reflns.pdbx_diffrn_id                   1 
_reflns.pdbx_ordinal                     1 
_reflns.pdbx_CC_half                     ? 
_reflns.pdbx_R_split                     ? 
# 
_reflns_shell.d_res_high                  1.9 
_reflns_shell.d_res_low                   1.97 
_reflns_shell.meanI_over_sigI_all         ? 
_reflns_shell.meanI_over_sigI_obs         3.3 
_reflns_shell.number_measured_all         ? 
_reflns_shell.number_measured_obs         ? 
_reflns_shell.number_possible             ? 
_reflns_shell.number_unique_all           ? 
_reflns_shell.number_unique_obs           ? 
_reflns_shell.percent_possible_all        99 
_reflns_shell.percent_possible_obs        ? 
_reflns_shell.Rmerge_F_all                ? 
_reflns_shell.Rmerge_F_obs                ? 
_reflns_shell.Rmerge_I_all                ? 
_reflns_shell.Rmerge_I_obs                0.507 
_reflns_shell.meanI_over_sigI_gt          ? 
_reflns_shell.meanI_over_uI_all           ? 
_reflns_shell.meanI_over_uI_gt            ? 
_reflns_shell.number_measured_gt          ? 
_reflns_shell.number_unique_gt            ? 
_reflns_shell.percent_possible_gt         ? 
_reflns_shell.Rmerge_F_gt                 ? 
_reflns_shell.Rmerge_I_gt                 ? 
_reflns_shell.pdbx_redundancy             5.9 
_reflns_shell.pdbx_Rsym_value             ? 
_reflns_shell.pdbx_chi_squared            ? 
_reflns_shell.pdbx_netI_over_sigmaI_all   ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs   ? 
_reflns_shell.pdbx_Rrim_I_all             ? 
_reflns_shell.pdbx_Rpim_I_all             ? 
_reflns_shell.pdbx_rejects                ? 
_reflns_shell.pdbx_ordinal                1 
_reflns_shell.pdbx_diffrn_id              1 
_reflns_shell.pdbx_CC_half                ? 
_reflns_shell.pdbx_R_split                ? 
# 
_computing.entry_id                           5HBW 
_computing.cell_refinement                    ? 
_computing.data_collection                    ? 
_computing.data_reduction                     ? 
_computing.molecular_graphics                 ? 
_computing.publication_material               ? 
_computing.structure_refinement               'REFMAC 5.8.0049' 
_computing.structure_solution                 ? 
_computing.pdbx_structure_refinement_method   ? 
_computing.pdbx_data_reduction_ii             ? 
_computing.pdbx_data_reduction_ds             ? 
# 
_refine.aniso_B[1][1]                            0.01 
_refine.aniso_B[1][2]                            -0.00 
_refine.aniso_B[1][3]                            0.00 
_refine.aniso_B[2][2]                            0.03 
_refine.aniso_B[2][3]                            -0.00 
_refine.aniso_B[3][3]                            -0.05 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               33.770 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.965 
_refine.correlation_coeff_Fo_to_Fc_free          0.960 
_refine.details                                  'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 5HBW 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.90 
_refine.ls_d_res_low                             23.44 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     3841 
_refine.ls_number_reflns_R_free                  195 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.56 
_refine.ls_percent_reflns_R_free                 4.8 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.21857 
_refine.ls_R_factor_R_free                       0.25416 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.21696 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    MASK 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      1DNS 
_refine.pdbx_stereochemistry_target_values       'MAXIMUM LIKELIHOOD' 
_refine.pdbx_R_Free_selection_details            RANDOM 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.162 
_refine.pdbx_overall_ESU_R_Free                  0.150 
_refine.pdbx_solvent_vdw_probe_radii             1.20 
_refine.pdbx_solvent_ion_probe_radii             0.80 
_refine.pdbx_solvent_shrinkage_radii             0.80 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             3.969 
_refine.overall_SU_ML                            0.104 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         1 
_refine_hist.pdbx_number_atoms_protein        0 
_refine_hist.pdbx_number_atoms_nucleic_acid   298 
_refine_hist.pdbx_number_atoms_ligand         58 
_refine_hist.number_atoms_solvent             3 
_refine_hist.number_atoms_total               359 
_refine_hist.d_res_high                       1.90 
_refine_hist.d_res_low                        23.44 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.037 0.019  394 ? r_bond_refined_d             ? ? 
'X-RAY DIFFRACTION' ? 0.038 0.025  184 ? r_bond_other_d               ? ? 
'X-RAY DIFFRACTION' ? 3.485 2.234  606 ? r_angle_refined_deg          ? ? 
'X-RAY DIFFRACTION' ? 4.588 3.336  440 ? r_angle_other_deg            ? ? 
'X-RAY DIFFRACTION' ? ?     ?      ?   ? r_dihedral_angle_1_deg       ? ? 
'X-RAY DIFFRACTION' ? ?     ?      ?   ? r_dihedral_angle_2_deg       ? ? 
'X-RAY DIFFRACTION' ? ?     ?      ?   ? r_dihedral_angle_3_deg       ? ? 
'X-RAY DIFFRACTION' ? ?     ?      ?   ? r_dihedral_angle_4_deg       ? ? 
'X-RAY DIFFRACTION' ? 0.166 0.200  70  ? r_chiral_restr               ? ? 
'X-RAY DIFFRACTION' ? 0.020 0.021  206 ? r_gen_planes_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.003 0.022  72  ? r_gen_planes_other           ? ? 
'X-RAY DIFFRACTION' ? ?     ?      ?   ? r_nbd_refined                ? ? 
'X-RAY DIFFRACTION' ? ?     ?      ?   ? r_nbd_other                  ? ? 
'X-RAY DIFFRACTION' ? ?     ?      ?   ? r_nbtor_refined              ? ? 
'X-RAY DIFFRACTION' ? ?     ?      ?   ? r_nbtor_other                ? ? 
'X-RAY DIFFRACTION' ? ?     ?      ?   ? r_xyhbond_nbd_refined        ? ? 
'X-RAY DIFFRACTION' ? ?     ?      ?   ? r_xyhbond_nbd_other          ? ? 
'X-RAY DIFFRACTION' ? ?     ?      ?   ? r_metal_ion_refined          ? ? 
'X-RAY DIFFRACTION' ? ?     ?      ?   ? r_metal_ion_other            ? ? 
'X-RAY DIFFRACTION' ? ?     ?      ?   ? r_symmetry_vdw_refined       ? ? 
'X-RAY DIFFRACTION' ? ?     ?      ?   ? r_symmetry_vdw_other         ? ? 
'X-RAY DIFFRACTION' ? ?     ?      ?   ? r_symmetry_hbond_refined     ? ? 
'X-RAY DIFFRACTION' ? ?     ?      ?   ? r_symmetry_hbond_other       ? ? 
'X-RAY DIFFRACTION' ? ?     ?      ?   ? r_symmetry_metal_ion_refined ? ? 
'X-RAY DIFFRACTION' ? ?     ?      ?   ? r_symmetry_metal_ion_other   ? ? 
'X-RAY DIFFRACTION' ? ?     ?      ?   ? r_mcbond_it                  ? ? 
'X-RAY DIFFRACTION' ? ?     ?      ?   ? r_mcbond_other               ? ? 
'X-RAY DIFFRACTION' ? ?     ?      ?   ? r_mcangle_it                 ? ? 
'X-RAY DIFFRACTION' ? ?     ?      ?   ? r_mcangle_other              ? ? 
'X-RAY DIFFRACTION' ? 3.580 3.547  394 ? r_scbond_it                  ? ? 
'X-RAY DIFFRACTION' ? 3.575 3.554  395 ? r_scbond_other               ? ? 
'X-RAY DIFFRACTION' ? ?     ?      ?   ? r_scangle_it                 ? ? 
'X-RAY DIFFRACTION' ? 4.877 5.333  607 ? r_scangle_other              ? ? 
'X-RAY DIFFRACTION' ? 5.501 33.694 572 ? r_long_range_B_refined       ? ? 
'X-RAY DIFFRACTION' ? 5.496 33.760 573 ? r_long_range_B_other         ? ? 
'X-RAY DIFFRACTION' ? ?     ?      ?   ? r_rigid_bond_restr           ? ? 
'X-RAY DIFFRACTION' ? ?     ?      ?   ? r_sphericity_free            ? ? 
'X-RAY DIFFRACTION' ? ?     ?      ?   ? r_sphericity_bonded          ? ? 
# 
_refine_ls_shell.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_ls_shell.d_res_high                       1.898 
_refine_ls_shell.d_res_low                        1.947 
_refine_ls_shell.number_reflns_all                ? 
_refine_ls_shell.number_reflns_obs                ? 
_refine_ls_shell.number_reflns_R_free             20 
_refine_ls_shell.number_reflns_R_work             250 
_refine_ls_shell.percent_reflns_obs               96.43 
_refine_ls_shell.percent_reflns_R_free            ? 
_refine_ls_shell.R_factor_all                     ? 
_refine_ls_shell.R_factor_obs                     ? 
_refine_ls_shell.R_factor_R_free                  0.307 
_refine_ls_shell.R_factor_R_free_error            ? 
_refine_ls_shell.R_factor_R_work                  0.291 
_refine_ls_shell.redundancy_reflns_all            ? 
_refine_ls_shell.redundancy_reflns_obs            ? 
_refine_ls_shell.wR_factor_all                    ? 
_refine_ls_shell.wR_factor_obs                    ? 
_refine_ls_shell.wR_factor_R_free                 ? 
_refine_ls_shell.wR_factor_R_work                 ? 
_refine_ls_shell.pdbx_total_number_of_bins_used   20 
_refine_ls_shell.pdbx_phase_error                 ? 
_refine_ls_shell.pdbx_fsc_work                    ? 
_refine_ls_shell.pdbx_fsc_free                    ? 
# 
_struct.entry_id                     5HBW 
_struct.title                        'RNA primer-template complex with 2-methylimidazole-activated monomer analogue' 
_struct.pdbx_descriptor              
;RNA (5'-R(*(LCC)P*(TLN)P*(LCG)P*UP*AP*CP*A)-3')
;
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               ? 
# 
_struct_keywords.entry_id        5HBW 
_struct_keywords.text            RNA 
_struct_keywords.pdbx_keywords   RNA 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 2 ? 
E N N 3 ? 
F N N 3 ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
covale1  covale both ? A LCC 1 "O3'" ? ? ? 1_555 A TLN 2 P  ? ? A LCC 1 A TLN 2 1_555 ? ? ? ? ? ? ?            1.643 ? 
covale2  covale both ? A TLN 2 "O3'" ? ? ? 1_555 A LCG 3 P  ? ? A TLN 2 A LCG 3 1_555 ? ? ? ? ? ? ?            1.681 ? 
covale3  covale both ? A LCG 3 "O3'" ? ? ? 1_555 A U   4 P  ? ? A LCG 3 A U   4 1_555 ? ? ? ? ? ? ?            1.653 ? 
covale4  covale both ? B LCC 1 "O3'" ? ? ? 1_555 B TLN 2 P  ? ? B LCC 1 B TLN 2 1_555 ? ? ? ? ? ? ?            1.604 ? 
covale5  covale both ? B TLN 2 "O3'" ? ? ? 1_555 B LCG 3 P  ? ? B TLN 2 B LCG 3 1_555 ? ? ? ? ? ? ?            1.631 ? 
covale6  covale both ? B LCG 3 "O3'" ? ? ? 1_555 B U   4 P  ? ? B LCG 3 B U   4 1_555 ? ? ? ? ? ? ?            1.580 ? 
hydrog1  hydrog ?    ? A TLN 2 N3    ? ? ? 1_555 B A   7 N1 ? ? A TLN 2 B A   7 1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? 
hydrog2  hydrog ?    ? A TLN 2 O4    ? ? ? 1_555 B A   7 N6 ? ? A TLN 2 B A   7 1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? 
hydrog3  hydrog ?    ? A LCG 3 N1    ? ? ? 1_555 B C   6 N3 ? ? A LCG 3 B C   6 1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? 
hydrog4  hydrog ?    ? A LCG 3 N2    ? ? ? 1_555 B C   6 O2 ? ? A LCG 3 B C   6 1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? 
hydrog5  hydrog ?    ? A LCG 3 O6    ? ? ? 1_555 B C   6 N4 ? ? A LCG 3 B C   6 1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? 
hydrog6  hydrog ?    ? A U   4 N3    ? ? ? 1_555 B A   5 N1 ? ? A U   4 B A   5 1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? 
hydrog7  hydrog ?    ? A U   4 O4    ? ? ? 1_555 B A   5 N6 ? ? A U   4 B A   5 1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? 
hydrog8  hydrog ?    ? A A   5 N1    ? ? ? 1_555 B U   4 N3 ? ? A A   5 B U   4 1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? 
hydrog9  hydrog ?    ? A A   5 N6    ? ? ? 1_555 B U   4 O4 ? ? A A   5 B U   4 1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? 
hydrog10 hydrog ?    ? A C   6 N3    ? ? ? 1_555 B LCG 3 N1 ? ? A C   6 B LCG 3 1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? 
hydrog11 hydrog ?    ? A C   6 N4    ? ? ? 1_555 B LCG 3 O6 ? ? A C   6 B LCG 3 1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? 
hydrog12 hydrog ?    ? A C   6 O2    ? ? ? 1_555 B LCG 3 N2 ? ? A C   6 B LCG 3 1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? 
hydrog13 hydrog ?    ? A A   7 N1    ? ? ? 1_555 B TLN 2 N3 ? ? A A   7 B TLN 2 1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? 
hydrog14 hydrog ?    ? A A   7 N6    ? ? ? 1_555 B TLN 2 O4 ? ? A A   7 B TLN 2 1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
covale ? ? 
hydrog ? ? 
# 
loop_
_struct_site.id 
_struct_site.pdbx_evidence_code 
_struct_site.pdbx_auth_asym_id 
_struct_site.pdbx_auth_comp_id 
_struct_site.pdbx_auth_seq_id 
_struct_site.pdbx_auth_ins_code 
_struct_site.pdbx_num_residues 
_struct_site.details 
AC1 Software A PZG 101 ? 8 'binding site for residue PZG A 101' 
AC2 Software B PZG 101 ? 8 'binding site for residue PZG B 101' 
# 
loop_
_struct_site_gen.id 
_struct_site_gen.site_id 
_struct_site_gen.pdbx_num_res 
_struct_site_gen.label_comp_id 
_struct_site_gen.label_asym_id 
_struct_site_gen.label_seq_id 
_struct_site_gen.pdbx_auth_ins_code 
_struct_site_gen.auth_comp_id 
_struct_site_gen.auth_asym_id 
_struct_site_gen.auth_seq_id 
_struct_site_gen.label_atom_id 
_struct_site_gen.label_alt_id 
_struct_site_gen.symmetry 
_struct_site_gen.details 
1  AC1 8 LCC A 1 ? LCC A 1 . ? 1_555 ? 
2  AC1 8 TLN A 2 ? TLN A 2 . ? 1_555 ? 
3  AC1 8 U   A 4 ? U   A 4 . ? 3_555 ? 
4  AC1 8 A   A 5 ? A   A 5 . ? 3_555 ? 
5  AC1 8 C   A 6 ? C   A 6 . ? 3_555 ? 
6  AC1 8 A   A 7 ? A   A 7 . ? 2_555 ? 
7  AC1 8 LCC B 1 ? LCC B 1 . ? 3_655 ? 
8  AC1 8 A   B 7 ? A   B 7 . ? 1_555 ? 
9  AC2 8 LCC A 1 ? LCC A 1 . ? 3_645 ? 
10 AC2 8 TLN A 2 ? TLN A 2 . ? 3_645 ? 
11 AC2 8 C   A 6 ? C   A 6 . ? 4_545 ? 
12 AC2 8 A   A 7 ? A   A 7 . ? 1_555 ? 
13 AC2 8 A   A 7 ? A   A 7 . ? 4_545 ? 
14 AC2 8 LCC B 1 ? LCC B 1 . ? 1_555 ? 
15 AC2 8 TLN B 2 ? TLN B 2 . ? 4_445 ? 
16 AC2 8 TLN B 2 ? TLN B 2 . ? 1_555 ? 
# 
_atom_sites.entry_id                    5HBW 
_atom_sites.fract_transf_matrix[1][1]   0.035618 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   -0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.025159 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   -0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.023478 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.Cartn_x_esd 
_atom_site.Cartn_y_esd 
_atom_site.Cartn_z_esd 
_atom_site.occupancy_esd 
_atom_site.B_iso_or_equiv_esd 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
HETATM 1   O "O5'" . LCC A 1 1 ? 17.377 6.916   16.541 1.00 32.40 ? ? ? ? ? ? 1   LCC A "O5'" 1 
HETATM 2   C "C5'" . LCC A 1 1 ? 17.010 6.897   17.904 1.00 29.95 ? ? ? ? ? ? 1   LCC A "C5'" 1 
HETATM 3   C "C4'" . LCC A 1 1 ? 15.558 7.147   17.758 1.00 30.22 ? ? ? ? ? ? 1   LCC A "C4'" 1 
HETATM 4   O "O4'" . LCC A 1 1 ? 15.245 8.359   17.003 1.00 28.62 ? ? ? ? ? ? 1   LCC A "O4'" 1 
HETATM 5   C "C1'" . LCC A 1 1 ? 13.853 8.277   16.695 1.00 27.74 ? ? ? ? ? ? 1   LCC A "C1'" 1 
HETATM 6   N N1    . LCC A 1 1 ? 13.566 8.440   15.308 1.00 29.66 ? ? ? ? ? ? 1   LCC A N1    1 
HETATM 7   C C6    . LCC A 1 1 ? 14.629 8.440   14.441 1.00 30.92 ? ? ? ? ? ? 1   LCC A C6    1 
HETATM 8   C C5    . LCC A 1 1 ? 14.416 8.650   13.138 1.00 32.40 ? ? ? ? ? ? 1   LCC A C5    1 
HETATM 9   C C5M   . LCC A 1 1 ? 15.549 8.649   12.281 1.00 37.74 ? ? ? ? ? ? 1   LCC A C5M   1 
HETATM 10  C C4    . LCC A 1 1 ? 13.100 8.899   12.734 1.00 33.12 ? ? ? ? ? ? 1   LCC A C4    1 
HETATM 11  N N4    . LCC A 1 1 ? 12.913 9.114   11.424 1.00 31.11 ? ? ? ? ? ? 1   LCC A N4    1 
HETATM 12  N N3    . LCC A 1 1 ? 12.058 8.920   13.614 1.00 30.62 ? ? ? ? ? ? 1   LCC A N3    1 
HETATM 13  C C2    . LCC A 1 1 ? 12.310 8.687   14.877 1.00 29.58 ? ? ? ? ? ? 1   LCC A C2    1 
HETATM 14  O O2    . LCC A 1 1 ? 11.371 8.691   15.639 1.00 28.42 ? ? ? ? ? ? 1   LCC A O2    1 
HETATM 15  C "C3'" . LCC A 1 1 ? 14.788 6.208   16.932 1.00 29.94 ? ? ? ? ? ? 1   LCC A "C3'" 1 
HETATM 16  C "C2'" . LCC A 1 1 ? 13.487 6.977   17.227 1.00 29.57 ? ? ? ? ? ? 1   LCC A "C2'" 1 
HETATM 17  O "O2'" . LCC A 1 1 ? 13.462 7.054   18.578 1.00 28.77 ? ? ? ? ? ? 1   LCC A "O2'" 1 
HETATM 18  O "O3'" . LCC A 1 1 ? 14.722 4.889   17.398 1.00 34.62 ? ? ? ? ? ? 1   LCC A "O3'" 1 
HETATM 19  C "C6'" . LCC A 1 1 ? 14.833 7.158   19.123 1.00 29.13 ? ? ? ? ? ? 1   LCC A "C6'" 1 
HETATM 20  P P     . TLN A 1 2 ? 14.132 3.578   16.603 1.00 35.30 ? ? ? ? ? ? 2   TLN A P     1 
HETATM 21  O OP1   . TLN A 1 2 ? 14.575 2.419   17.391 1.00 35.27 ? ? ? ? ? ? 2   TLN A OP1   1 
HETATM 22  O OP2   . TLN A 1 2 ? 14.644 3.814   15.264 1.00 31.70 ? ? ? ? ? ? 2   TLN A OP2   1 
HETATM 23  O "O5'" . TLN A 1 2 ? 12.559 3.622   16.704 1.00 29.65 ? ? ? ? ? ? 2   TLN A "O5'" 1 
HETATM 24  C "C5'" . TLN A 1 2 ? 11.917 3.702   18.003 1.00 28.26 ? ? ? ? ? ? 2   TLN A "C5'" 1 
HETATM 25  C "C4'" . TLN A 1 2 ? 10.472 4.093   17.679 1.00 30.56 ? ? ? ? ? ? 2   TLN A "C4'" 1 
HETATM 26  O "O4'" . TLN A 1 2 ? 10.331 5.339   16.952 1.00 27.86 ? ? ? ? ? ? 2   TLN A "O4'" 1 
HETATM 27  C "C1'" . TLN A 1 2 ? 9.040  5.166   16.311 1.00 28.09 ? ? ? ? ? ? 2   TLN A "C1'" 1 
HETATM 28  N N1    . TLN A 1 2 ? 9.141  5.379   14.859 1.00 29.48 ? ? ? ? ? ? 2   TLN A N1    1 
HETATM 29  C C6    . TLN A 1 2 ? 10.443 5.405   14.219 1.00 31.52 ? ? ? ? ? ? 2   TLN A C6    1 
HETATM 30  C C5    . TLN A 1 2 ? 10.603 5.694   12.881 1.00 30.54 ? ? ? ? ? ? 2   TLN A C5    1 
HETATM 31  C C5M   . TLN A 1 2 ? 11.870 5.642   12.315 1.00 30.61 ? ? ? ? ? ? 2   TLN A C5M   1 
HETATM 32  C C4    . TLN A 1 2 ? 9.428  6.009   12.150 1.00 33.67 ? ? ? ? ? ? 2   TLN A C4    1 
HETATM 33  O O4    . TLN A 1 2 ? 9.442  6.340   10.965 1.00 31.51 ? ? ? ? ? ? 2   TLN A O4    1 
HETATM 34  N N3    . TLN A 1 2 ? 8.164  5.991   12.780 1.00 29.51 ? ? ? ? ? ? 2   TLN A N3    1 
HETATM 35  C C2    . TLN A 1 2 ? 8.024  5.703   14.133 1.00 31.67 ? ? ? ? ? ? 2   TLN A C2    1 
HETATM 36  O O2    . TLN A 1 2 ? 6.889  5.723   14.603 1.00 27.91 ? ? ? ? ? ? 2   TLN A O2    1 
HETATM 37  C "C3'" . TLN A 1 2 ? 9.732  3.107   16.816 1.00 30.53 ? ? ? ? ? ? 2   TLN A "C3'" 1 
HETATM 38  C "C2'" . TLN A 1 2 ? 8.495  3.892   16.828 1.00 30.12 ? ? ? ? ? ? 2   TLN A "C2'" 1 
HETATM 39  O "O2'" . TLN A 1 2 ? 8.243  3.988   18.219 1.00 29.57 ? ? ? ? ? ? 2   TLN A "O2'" 1 
HETATM 40  O "O3'" . TLN A 1 2 ? 9.345  1.806   17.413 1.00 35.79 ? ? ? ? ? ? 2   TLN A "O3'" 1 
HETATM 41  C "C6'" . TLN A 1 2 ? 9.584  4.145   18.909 1.00 31.15 ? ? ? ? ? ? 2   TLN A "C6'" 1 
HETATM 42  P P     . LCG A 1 3 ? 9.336  0.369   16.540 1.00 36.22 ? ? ? ? ? ? 3   LCG A P     1 
HETATM 43  O OP1   . LCG A 1 3 ? 9.258  -0.656  17.593 1.00 35.19 ? ? ? ? ? ? 3   LCG A OP1   1 
HETATM 44  O "O5'" . LCG A 1 3 ? 7.930  0.683   15.972 1.00 30.82 ? ? ? ? ? ? 3   LCG A "O5'" 1 
HETATM 45  C "C5'" . LCG A 1 3 ? 6.753  0.467   16.839 1.00 34.29 ? ? ? ? ? ? 3   LCG A "C5'" 1 
HETATM 46  C "C3'" . LCG A 1 3 ? 5.280  0.244   14.804 1.00 31.63 ? ? ? ? ? ? 3   LCG A "C3'" 1 
HETATM 47  C "C6'" . LCG A 1 3 ? 4.296  1.000   16.799 1.00 33.94 ? ? ? ? ? ? 3   LCG A "C6'" 1 
HETATM 48  N N9    . LCG A 1 3 ? 5.763  2.604   13.136 1.00 30.39 ? ? ? ? ? ? 3   LCG A N9    1 
HETATM 49  C C8    . LCG A 1 3 ? 7.097  2.542   13.023 1.00 28.57 ? ? ? ? ? ? 3   LCG A C8    1 
HETATM 50  C C4    . LCG A 1 3 ? 5.238  3.036   12.000 1.00 28.36 ? ? ? ? ? ? 3   LCG A C4    1 
HETATM 51  N N7    . LCG A 1 3 ? 7.426  2.961   11.814 1.00 29.56 ? ? ? ? ? ? 3   LCG A N7    1 
HETATM 52  C C5    . LCG A 1 3 ? 6.278  3.241   11.148 1.00 30.85 ? ? ? ? ? ? 3   LCG A C5    1 
HETATM 53  C C6    . LCG A 1 3 ? 6.013  3.648   9.874  1.00 28.09 ? ? ? ? ? ? 3   LCG A C6    1 
HETATM 54  C "C2'" . LCG A 1 3 ? 4.186  1.098   14.425 1.00 32.39 ? ? ? ? ? ? 3   LCG A "C2'" 1 
HETATM 55  O O6    . LCG A 1 3 ? 6.891  3.887   9.062  1.00 26.51 ? ? ? ? ? ? 3   LCG A O6    1 
HETATM 56  C "C4'" . LCG A 1 3 ? 5.611  1.023   16.032 1.00 33.35 ? ? ? ? ? ? 3   LCG A "C4'" 1 
HETATM 57  C "C1'" . LCG A 1 3 ? 4.863  2.363   14.321 1.00 31.81 ? ? ? ? ? ? 3   LCG A "C1'" 1 
HETATM 58  C C2    . LCG A 1 3 ? 3.655  3.692   10.432 1.00 30.91 ? ? ? ? ? ? 3   LCG A C2    1 
HETATM 59  N N1    . LCG A 1 3 ? 4.702  3.895   9.533  1.00 29.40 ? ? ? ? ? ? 3   LCG A N1    1 
HETATM 60  O "O4'" . LCG A 1 3 ? 5.843  2.311   15.454 1.00 32.90 ? ? ? ? ? ? 3   LCG A "O4'" 1 
HETATM 61  O OP2   . LCG A 1 3 ? 10.176 0.364   15.316 1.00 32.75 ? ? ? ? ? ? 3   LCG A OP2   1 
HETATM 62  N N2    . LCG A 1 3 ? 2.411  3.943   10.062 1.00 32.48 ? ? ? ? ? ? 3   LCG A N2    1 
HETATM 63  N N3    . LCG A 1 3 ? 3.947  3.227   11.665 1.00 28.20 ? ? ? ? ? ? 3   LCG A N3    1 
HETATM 64  O "O2'" . LCG A 1 3 ? 3.391  1.140   15.614 1.00 34.45 ? ? ? ? ? ? 3   LCG A "O2'" 1 
HETATM 65  O "O3'" . LCG A 1 3 ? 4.807  -1.038  15.113 1.00 36.32 ? ? ? ? ? ? 3   LCG A "O3'" 1 
ATOM   66  P P     . U   A 1 4 ? 4.983  -2.421  14.225 1.00 35.87 ? ? ? ? ? ? 4   U   A P     1 
ATOM   67  O OP1   . U   A 1 4 ? 4.756  -3.501  15.189 1.00 48.82 ? ? ? ? ? ? 4   U   A OP1   1 
ATOM   68  O OP2   . U   A 1 4 ? 6.246  -2.375  13.493 1.00 41.59 ? ? ? ? ? ? 4   U   A OP2   1 
ATOM   69  O "O5'" . U   A 1 4 ? 3.791  -2.188  13.201 1.00 35.30 ? ? ? ? ? ? 4   U   A "O5'" 1 
ATOM   70  C "C5'" . U   A 1 4 ? 2.415  -2.028  13.586 1.00 34.69 ? ? ? ? ? ? 4   U   A "C5'" 1 
ATOM   71  C "C4'" . U   A 1 4 ? 1.594  -1.534  12.429 1.00 31.72 ? ? ? ? ? ? 4   U   A "C4'" 1 
ATOM   72  O "O4'" . U   A 1 4 ? 2.011  -0.210  12.017 1.00 30.99 ? ? ? ? ? ? 4   U   A "O4'" 1 
ATOM   73  C "C3'" . U   A 1 4 ? 1.675  -2.321  11.135 1.00 34.43 ? ? ? ? ? ? 4   U   A "C3'" 1 
ATOM   74  O "O3'" . U   A 1 4 ? 0.842  -3.447  11.175 1.00 33.31 ? ? ? ? ? ? 4   U   A "O3'" 1 
ATOM   75  C "C2'" . U   A 1 4 ? 1.106  -1.320  10.154 1.00 34.11 ? ? ? ? ? ? 4   U   A "C2'" 1 
ATOM   76  O "O2'" . U   A 1 4 ? -0.305 -1.153  10.230 1.00 37.97 ? ? ? ? ? ? 4   U   A "O2'" 1 
ATOM   77  C "C1'" . U   A 1 4 ? 1.809  -0.050  10.623 1.00 35.61 ? ? ? ? ? ? 4   U   A "C1'" 1 
ATOM   78  N N1    . U   A 1 4 ? 3.122  0.128   10.001 1.00 33.28 ? ? ? ? ? ? 4   U   A N1    1 
ATOM   79  C C2    . U   A 1 4 ? 3.199  0.592   8.697  1.00 30.57 ? ? ? ? ? ? 4   U   A C2    1 
ATOM   80  O O2    . U   A 1 4 ? 2.222  0.885   8.031  1.00 34.19 ? ? ? ? ? ? 4   U   A O2    1 
ATOM   81  N N3    . U   A 1 4 ? 4.473  0.756   8.228  1.00 31.08 ? ? ? ? ? ? 4   U   A N3    1 
ATOM   82  C C4    . U   A 1 4 ? 5.648  0.506   8.903  1.00 27.79 ? ? ? ? ? ? 4   U   A C4    1 
ATOM   83  O O4    . U   A 1 4 ? 6.719  0.732   8.353  1.00 26.69 ? ? ? ? ? ? 4   U   A O4    1 
ATOM   84  C C5    . U   A 1 4 ? 5.479  0.033   10.234 1.00 28.95 ? ? ? ? ? ? 4   U   A C5    1 
ATOM   85  C C6    . U   A 1 4 ? 4.257  -0.170  10.713 1.00 29.59 ? ? ? ? ? ? 4   U   A C6    1 
ATOM   86  P P     . A   A 1 5 ? 1.221  -4.745  10.358 1.00 36.73 ? ? ? ? ? ? 5   A   A P     1 
ATOM   87  O OP1   . A   A 1 5 ? 0.416  -5.870  10.886 1.00 32.59 ? ? ? ? ? ? 5   A   A OP1   1 
ATOM   88  O OP2   . A   A 1 5 ? 2.671  -4.886  10.286 1.00 36.41 ? ? ? ? ? ? 5   A   A OP2   1 
ATOM   89  O "O5'" . A   A 1 5 ? 0.801  -4.336  8.882  1.00 33.37 ? ? ? ? ? ? 5   A   A "O5'" 1 
ATOM   90  C "C5'" . A   A 1 5 ? -0.542 -4.067  8.512  1.00 33.61 ? ? ? ? ? ? 5   A   A "C5'" 1 
ATOM   91  C "C4'" . A   A 1 5 ? -0.582 -3.625  7.065  1.00 30.97 ? ? ? ? ? ? 5   A   A "C4'" 1 
ATOM   92  O "O4'" . A   A 1 5 ? 0.113  -2.380  6.903  1.00 30.16 ? ? ? ? ? ? 5   A   A "O4'" 1 
ATOM   93  C "C3'" . A   A 1 5 ? 0.119  -4.559  6.097  1.00 33.38 ? ? ? ? ? ? 5   A   A "C3'" 1 
ATOM   94  O "O3'" . A   A 1 5 ? -0.756 -5.609  5.744  1.00 31.66 ? ? ? ? ? ? 5   A   A "O3'" 1 
ATOM   95  C "C2'" . A   A 1 5 ? 0.401  -3.640  4.937  1.00 32.98 ? ? ? ? ? ? 5   A   A "C2'" 1 
ATOM   96  O "O2'" . A   A 1 5 ? -0.745 -3.210  4.272  1.00 34.86 ? ? ? ? ? ? 5   A   A "O2'" 1 
ATOM   97  C "C1'" . A   A 1 5 ? 0.802  -2.382  5.672  1.00 32.63 ? ? ? ? ? ? 5   A   A "C1'" 1 
ATOM   98  N N9    . A   A 1 5 ? 2.226  -2.288  5.940  1.00 31.94 ? ? ? ? ? ? 5   A   A N9    1 
ATOM   99  C C8    . A   A 1 5 ? 2.911  -2.652  7.069  1.00 29.35 ? ? ? ? ? ? 5   A   A C8    1 
ATOM   100 N N7    . A   A 1 5 ? 4.184  -2.353  7.031  1.00 29.11 ? ? ? ? ? ? 5   A   A N7    1 
ATOM   101 C C5    . A   A 1 5 ? 4.353  -1.780  5.780  1.00 26.95 ? ? ? ? ? ? 5   A   A C5    1 
ATOM   102 C C6    . A   A 1 5 ? 5.486  -1.280  5.122  1.00 27.36 ? ? ? ? ? ? 5   A   A C6    1 
ATOM   103 N N6    . A   A 1 5 ? 6.708  -1.256  5.666  1.00 24.69 ? ? ? ? ? ? 5   A   A N6    1 
ATOM   104 N N1    . A   A 1 5 ? 5.321  -0.790  3.879  1.00 26.63 ? ? ? ? ? ? 5   A   A N1    1 
ATOM   105 C C2    . A   A 1 5 ? 4.096  -0.826  3.331  1.00 29.16 ? ? ? ? ? ? 5   A   A C2    1 
ATOM   106 N N3    . A   A 1 5 ? 2.959  -1.287  3.842  1.00 29.16 ? ? ? ? ? ? 5   A   A N3    1 
ATOM   107 C C4    . A   A 1 5 ? 3.160  -1.752  5.089  1.00 28.64 ? ? ? ? ? ? 5   A   A C4    1 
ATOM   108 P P     . C   A 1 6 ? -0.205 -7.035  5.419  1.00 33.40 ? ? ? ? ? ? 6   C   A P     1 
ATOM   109 O OP1   . C   A 1 6 ? -1.397 -7.927  5.362  1.00 33.48 ? ? ? ? ? ? 6   C   A OP1   1 
ATOM   110 O OP2   . C   A 1 6 ? 0.893  -7.354  6.365  1.00 35.89 ? ? ? ? ? ? 6   C   A OP2   1 
ATOM   111 O "O5'" . C   A 1 6 ? 0.414  -6.916  3.934  1.00 30.66 ? ? ? ? ? ? 6   C   A "O5'" 1 
ATOM   112 C "C5'" . C   A 1 6 ? -0.397 -6.687  2.771  1.00 27.56 ? ? ? ? ? ? 6   C   A "C5'" 1 
ATOM   113 C "C4'" . C   A 1 6 ? 0.451  -6.134  1.650  1.00 30.87 ? ? ? ? ? ? 6   C   A "C4'" 1 
ATOM   114 O "O4'" . C   A 1 6 ? 1.094  -4.889  2.055  1.00 31.02 ? ? ? ? ? ? 6   C   A "O4'" 1 
ATOM   115 C "C3'" . C   A 1 6 ? 1.610  -6.992  1.163  1.00 32.50 ? ? ? ? ? ? 6   C   A "C3'" 1 
ATOM   116 O "O3'" . C   A 1 6 ? 1.236  -8.112  0.341  1.00 28.47 ? ? ? ? ? ? 6   C   A "O3'" 1 
ATOM   117 C "C2'" . C   A 1 6 ? 2.452  -5.956  0.439  1.00 28.71 ? ? ? ? ? ? 6   C   A "C2'" 1 
ATOM   118 O "O2'" . C   A 1 6 ? 1.839  -5.639  -0.766 1.00 28.24 ? ? ? ? ? ? 6   C   A "O2'" 1 
ATOM   119 C "C1'" . C   A 1 6 ? 2.338  -4.761  1.382  1.00 31.61 ? ? ? ? ? ? 6   C   A "C1'" 1 
ATOM   120 N N1    . C   A 1 6 ? 3.444  -4.710  2.374  1.00 28.55 ? ? ? ? ? ? 6   C   A N1    1 
ATOM   121 C C2    . C   A 1 6 ? 4.660  -4.108  2.002  1.00 25.53 ? ? ? ? ? ? 6   C   A C2    1 
ATOM   122 O O2    . C   A 1 6 ? 4.768  -3.623  0.867  1.00 26.36 ? ? ? ? ? ? 6   C   A O2    1 
ATOM   123 N N3    . C   A 1 6 ? 5.648  -4.010  2.909  1.00 23.06 ? ? ? ? ? ? 6   C   A N3    1 
ATOM   124 C C4    . C   A 1 6 ? 5.497  -4.558  4.116  1.00 26.61 ? ? ? ? ? ? 6   C   A C4    1 
ATOM   125 N N4    . C   A 1 6 ? 6.533  -4.512  4.966  1.00 26.40 ? ? ? ? ? ? 6   C   A N4    1 
ATOM   126 C C5    . C   A 1 6 ? 4.288  -5.209  4.504  1.00 29.90 ? ? ? ? ? ? 6   C   A C5    1 
ATOM   127 C C6    . C   A 1 6 ? 3.297  -5.258  3.611  1.00 27.87 ? ? ? ? ? ? 6   C   A C6    1 
ATOM   128 P P     . A   A 1 7 ? 2.046  -9.408  0.383  1.00 32.11 ? ? ? ? ? ? 7   A   A P     1 
ATOM   129 O OP1   . A   A 1 7 ? 1.251  -10.489 -0.310 1.00 36.80 ? ? ? ? ? ? 7   A   A OP1   1 
ATOM   130 O OP2   . A   A 1 7 ? 2.543  -9.671  1.713  1.00 33.01 ? ? ? ? ? ? 7   A   A OP2   1 
ATOM   131 O "O5'" . A   A 1 7 ? 3.332  -9.052  -0.507 1.00 28.00 ? ? ? ? ? ? 7   A   A "O5'" 1 
ATOM   132 C "C5'" . A   A 1 7 ? 3.352  -9.145  -1.919 1.00 30.86 ? ? ? ? ? ? 7   A   A "C5'" 1 
ATOM   133 C "C4'" . A   A 1 7 ? 4.602  -8.519  -2.447 1.00 27.86 ? ? ? ? ? ? 7   A   A "C4'" 1 
ATOM   134 O "O4'" . A   A 1 7 ? 4.942  -7.272  -1.765 1.00 29.08 ? ? ? ? ? ? 7   A   A "O4'" 1 
ATOM   135 C "C3'" . A   A 1 7 ? 5.822  -9.375  -2.230 1.00 27.86 ? ? ? ? ? ? 7   A   A "C3'" 1 
ATOM   136 O "O3'" . A   A 1 7 ? 5.837  -10.350 -3.216 1.00 29.76 ? ? ? ? ? ? 7   A   A "O3'" 1 
ATOM   137 C "C2'" . A   A 1 7 ? 6.911  -8.346  -2.426 1.00 29.90 ? ? ? ? ? ? 7   A   A "C2'" 1 
ATOM   138 O "O2'" . A   A 1 7 ? 7.042  -8.106  -3.819 1.00 33.37 ? ? ? ? ? ? 7   A   A "O2'" 1 
ATOM   139 C "C1'" . A   A 1 7 ? 6.357  -7.182  -1.617 1.00 26.54 ? ? ? ? ? ? 7   A   A "C1'" 1 
ATOM   140 N N9    . A   A 1 7 ? 6.696  -7.146  -0.179 1.00 29.24 ? ? ? ? ? ? 7   A   A N9    1 
ATOM   141 C C8    . A   A 1 7 ? 5.916  -7.477  0.902  1.00 27.40 ? ? ? ? ? ? 7   A   A C8    1 
ATOM   142 N N7    . A   A 1 7 ? 6.506  -7.287  2.055  1.00 25.82 ? ? ? ? ? ? 7   A   A N7    1 
ATOM   143 C C5    . A   A 1 7 ? 7.745  -6.768  1.716  1.00 29.28 ? ? ? ? ? ? 7   A   A C5    1 
ATOM   144 C C6    . A   A 1 7 ? 8.852  -6.362  2.491  1.00 30.80 ? ? ? ? ? ? 7   A   A C6    1 
ATOM   145 N N6    . A   A 1 7 ? 8.890  -6.405  3.820  1.00 27.87 ? ? ? ? ? ? 7   A   A N6    1 
ATOM   146 N N1    . A   A 1 7 ? 9.936  -5.908  1.840  1.00 28.34 ? ? ? ? ? ? 7   A   A N1    1 
ATOM   147 C C2    . A   A 1 7 ? 9.922  -5.893  0.507  1.00 28.66 ? ? ? ? ? ? 7   A   A C2    1 
ATOM   148 N N3    . A   A 1 7 ? 8.941  -6.221  -0.330 1.00 31.66 ? ? ? ? ? ? 7   A   A N3    1 
ATOM   149 C C4    . A   A 1 7 ? 7.869  -6.658  0.346  1.00 28.43 ? ? ? ? ? ? 7   A   A C4    1 
HETATM 150 O "O5'" . LCC B 1 1 ? 19.726 -6.084  9.664  1.00 40.49 ? ? ? ? ? ? 1   LCC B "O5'" 1 
HETATM 151 C "C5'" . LCC B 1 1 ? 20.641 -6.370  8.618  1.00 40.48 ? ? ? ? ? ? 1   LCC B "C5'" 1 
HETATM 152 C "C4'" . LCC B 1 1 ? 19.749 -6.711  7.430  1.00 37.96 ? ? ? ? ? ? 1   LCC B "C4'" 1 
HETATM 153 O "O4'" . LCC B 1 1 ? 18.845 -7.775  7.527  1.00 35.65 ? ? ? ? ? ? 1   LCC B "O4'" 1 
HETATM 154 C "C1'" . LCC B 1 1 ? 18.002 -7.667  6.446  1.00 34.92 ? ? ? ? ? ? 1   LCC B "C1'" 1 
HETATM 155 N N1    . LCC B 1 1 ? 16.594 -7.683  6.919  1.00 35.19 ? ? ? ? ? ? 1   LCC B N1    1 
HETATM 156 C C6    . LCC B 1 1 ? 16.289 -7.518  8.302  1.00 37.17 ? ? ? ? ? ? 1   LCC B C6    1 
HETATM 157 C C5    . LCC B 1 1 ? 14.970 -7.582  8.698  1.00 40.13 ? ? ? ? ? ? 1   LCC B C5    1 
HETATM 158 C C5M   . LCC B 1 1 ? 14.605 -7.422  10.013 1.00 46.36 ? ? ? ? ? ? 1   LCC B C5M   1 
HETATM 159 C C4    . LCC B 1 1 ? 14.015 -7.813  7.715  1.00 35.14 ? ? ? ? ? ? 1   LCC B C4    1 
HETATM 160 N N4    . LCC B 1 1 ? 12.772 -7.856  8.092  1.00 31.84 ? ? ? ? ? ? 1   LCC B N4    1 
HETATM 161 N N3    . LCC B 1 1 ? 14.354 -7.914  6.431  1.00 30.89 ? ? ? ? ? ? 1   LCC B N3    1 
HETATM 162 C C2    . LCC B 1 1 ? 15.616 -7.869  6.001  1.00 31.92 ? ? ? ? ? ? 1   LCC B C2    1 
HETATM 163 O O2    . LCC B 1 1 ? 15.848 -8.043  4.793  1.00 31.69 ? ? ? ? ? ? 1   LCC B O2    1 
HETATM 164 C "C3'" . LCC B 1 1 ? 18.841 -5.657  7.028  1.00 37.71 ? ? ? ? ? ? 1   LCC B "C3'" 1 
HETATM 165 C "C2'" . LCC B 1 1 ? 18.427 -6.376  5.857  1.00 35.85 ? ? ? ? ? ? 1   LCC B "C2'" 1 
HETATM 166 O "O2'" . LCC B 1 1 ? 19.647 -6.644  5.194  1.00 40.11 ? ? ? ? ? ? 1   LCC B "O2'" 1 
HETATM 167 O "O3'" . LCC B 1 1 ? 19.202 -4.276  6.542  1.00 40.10 ? ? ? ? ? ? 1   LCC B "O3'" 1 
HETATM 168 C "C6'" . LCC B 1 1 ? 20.620 -7.019  6.234  1.00 39.59 ? ? ? ? ? ? 1   LCC B "C6'" 1 
HETATM 169 P P     . TLN B 1 2 ? 18.605 -2.797  6.376  1.00 43.00 ? ? ? ? ? ? 2   TLN B P     1 
HETATM 170 O OP1   . TLN B 1 2 ? 19.717 -1.830  6.105  1.00 45.56 ? ? ? ? ? ? 2   TLN B OP1   1 
HETATM 171 O OP2   . TLN B 1 2 ? 17.431 -2.456  7.170  1.00 42.10 ? ? ? ? ? ? 2   TLN B OP2   1 
HETATM 172 O "O5'" . TLN B 1 2 ? 18.121 -3.307  4.922  1.00 39.95 ? ? ? ? ? ? 2   TLN B "O5'" 1 
HETATM 173 C "C5'" . TLN B 1 2 ? 18.869 -3.288  3.736  1.00 38.86 ? ? ? ? ? ? 2   TLN B "C5'" 1 
HETATM 174 C "C4'" . TLN B 1 2 ? 17.902 -3.712  2.690  1.00 38.82 ? ? ? ? ? ? 2   TLN B "C4'" 1 
HETATM 175 O "O4'" . TLN B 1 2 ? 17.197 -4.993  2.954  1.00 39.26 ? ? ? ? ? ? 2   TLN B "O4'" 1 
HETATM 176 C "C1'" . TLN B 1 2 ? 15.972 -4.767  2.061  1.00 39.39 ? ? ? ? ? ? 2   TLN B "C1'" 1 
HETATM 177 N N1    . TLN B 1 2 ? 14.749 -4.781  2.911  1.00 35.45 ? ? ? ? ? ? 2   TLN B N1    1 
HETATM 178 C C6    . TLN B 1 2 ? 14.843 -4.550  4.314  1.00 31.51 ? ? ? ? ? ? 2   TLN B C6    1 
HETATM 179 C C5    . TLN B 1 2 ? 13.704 -4.666  5.113  1.00 33.71 ? ? ? ? ? ? 2   TLN B C5    1 
HETATM 180 C C5M   . TLN B 1 2 ? 13.736 -4.431  6.518  1.00 31.06 ? ? ? ? ? ? 2   TLN B C5M   1 
HETATM 181 C C4    . TLN B 1 2 ? 12.494 -5.050  4.471  1.00 31.72 ? ? ? ? ? ? 2   TLN B C4    1 
HETATM 182 O O4    . TLN B 1 2 ? 11.468 -5.193  5.075  1.00 30.71 ? ? ? ? ? ? 2   TLN B O4    1 
HETATM 183 N N3    . TLN B 1 2 ? 12.449 -5.286  3.137  1.00 28.93 ? ? ? ? ? ? 2   TLN B N3    1 
HETATM 184 C C2    . TLN B 1 2 ? 13.597 -5.151  2.340  1.00 30.60 ? ? ? ? ? ? 2   TLN B C2    1 
HETATM 185 O O2    . TLN B 1 2 ? 13.539 -5.353  1.154  1.00 28.83 ? ? ? ? ? ? 2   TLN B O2    1 
HETATM 186 C "C3'" . TLN B 1 2 ? 16.869 -2.662  2.344  1.00 40.27 ? ? ? ? ? ? 2   TLN B "C3'" 1 
HETATM 187 C "C2'" . TLN B 1 2 ? 16.171 -3.475  1.335  1.00 39.31 ? ? ? ? ? ? 2   TLN B "C2'" 1 
HETATM 188 O "O2'" . TLN B 1 2 ? 17.200 -3.664  0.458  1.00 41.69 ? ? ? ? ? ? 2   TLN B "O2'" 1 
HETATM 189 O "O3'" . TLN B 1 2 ? 17.293 -1.358  1.643  1.00 36.91 ? ? ? ? ? ? 2   TLN B "O3'" 1 
HETATM 190 C "C6'" . TLN B 1 2 ? 18.503 -3.826  1.355  1.00 41.41 ? ? ? ? ? ? 2   TLN B "C6'" 1 
HETATM 191 P P     . LCG B 1 3 ? 16.632 0.061   2.100  1.00 42.03 ? ? ? ? ? ? 3   LCG B P     1 
HETATM 192 O OP1   . LCG B 1 3 ? 17.502 1.128   1.461  1.00 46.86 ? ? ? ? ? ? 3   LCG B OP1   1 
HETATM 193 O "O5'" . LCG B 1 3 ? 15.517 -0.322  0.953  1.00 43.83 ? ? ? ? ? ? 3   LCG B "O5'" 1 
HETATM 194 C "C5'" . LCG B 1 3 ? 15.668 -0.265  -0.497 1.00 37.76 ? ? ? ? ? ? 3   LCG B "C5'" 1 
HETATM 195 C "C3'" . LCG B 1 3 ? 13.267 0.356   -0.678 1.00 35.33 ? ? ? ? ? ? 3   LCG B "C3'" 1 
HETATM 196 C "C6'" . LCG B 1 3 ? 14.224 -0.706  -2.540 1.00 37.71 ? ? ? ? ? ? 3   LCG B "C6'" 1 
HETATM 197 N N9    . LCG B 1 3 ? 11.688 -1.946  0.809  1.00 31.19 ? ? ? ? ? ? 3   LCG B N9    1 
HETATM 198 C C8    . LCG B 1 3 ? 12.272 -1.825  1.995  1.00 29.53 ? ? ? ? ? ? 3   LCG B C8    1 
HETATM 199 C C4    . LCG B 1 3 ? 10.431 -2.323  0.966  1.00 27.41 ? ? ? ? ? ? 3   LCG B C4    1 
HETATM 200 N N7    . LCG B 1 3 ? 11.381 -2.131  2.920  1.00 28.65 ? ? ? ? ? ? 3   LCG B N7    1 
HETATM 201 C C5    . LCG B 1 3 ? 10.253 -2.427  2.270  1.00 27.38 ? ? ? ? ? ? 3   LCG B C5    1 
HETATM 202 C C6    . LCG B 1 3 ? 9.079  -2.804  2.767  1.00 30.65 ? ? ? ? ? ? 3   LCG B C6    1 
HETATM 203 C "C2'" . LCG B 1 3 ? 12.228 -0.471  -1.372 1.00 37.43 ? ? ? ? ? ? 3   LCG B "C2'" 1 
HETATM 204 O O6    . LCG B 1 3 ? 8.890  -2.942  4.009  1.00 27.72 ? ? ? ? ? ? 3   LCG B O6    1 
HETATM 205 C "C4'" . LCG B 1 3 ? 14.309 -0.638  -1.020 1.00 35.52 ? ? ? ? ? ? 3   LCG B "C4'" 1 
HETATM 206 C "C1'" . LCG B 1 3 ? 12.354 -1.791  -0.587 1.00 36.52 ? ? ? ? ? ? 3   LCG B "C1'" 1 
HETATM 207 C C2    . LCG B 1 3 ? 8.310  -2.958  0.457  1.00 24.60 ? ? ? ? ? ? 3   LCG B C2    1 
HETATM 208 N N1    . LCG B 1 3 ? 8.090  -3.063  1.812  1.00 27.10 ? ? ? ? ? ? 3   LCG B N1    1 
HETATM 209 O "O4'" . LCG B 1 3 ? 13.817 -1.930  -0.442 1.00 34.16 ? ? ? ? ? ? 3   LCG B "O4'" 1 
HETATM 210 O OP2   . LCG B 1 3 ? 15.750 0.341   3.220  1.00 48.52 ? ? ? ? ? ? 3   LCG B OP2   1 
HETATM 211 N N2    . LCG B 1 3 ? 7.303  -3.213  -0.393 1.00 28.20 ? ? ? ? ? ? 3   LCG B N2    1 
HETATM 212 N N3    . LCG B 1 3 ? 9.495  -2.584  0.019  1.00 24.82 ? ? ? ? ? ? 3   LCG B N3    1 
HETATM 213 O "O2'" . LCG B 1 3 ? 12.741 -0.663  -2.723 1.00 38.49 ? ? ? ? ? ? 3   LCG B "O2'" 1 
HETATM 214 O "O3'" . LCG B 1 3 ? 13.342 1.634   -1.354 1.00 32.93 ? ? ? ? ? ? 3   LCG B "O3'" 1 
ATOM   215 P P     . U   B 1 4 ? 12.697 2.927   -0.716 1.00 44.11 ? ? ? ? ? ? 4   U   B P     1 
ATOM   216 O OP1   . U   B 1 4 ? 13.586 3.712   -1.628 1.00 44.37 ? ? ? ? ? ? 4   U   B OP1   1 
ATOM   217 O OP2   . U   B 1 4 ? 12.580 3.309   0.712  1.00 41.93 ? ? ? ? ? ? 4   U   B OP2   1 
ATOM   218 O "O5'" . U   B 1 4 ? 11.190 3.139   -1.197 1.00 37.89 ? ? ? ? ? ? 4   U   B "O5'" 1 
ATOM   219 C "C5'" . U   B 1 4 ? 10.764 2.767   -2.518 1.00 35.97 ? ? ? ? ? ? 4   U   B "C5'" 1 
ATOM   220 C "C4'" . U   B 1 4 ? 9.297  2.428   -2.474 1.00 35.44 ? ? ? ? ? ? 4   U   B "C4'" 1 
ATOM   221 O "O4'" . U   B 1 4 ? 9.095  1.099   -1.880 1.00 32.26 ? ? ? ? ? ? 4   U   B "O4'" 1 
ATOM   222 C "C3'" . U   B 1 4 ? 8.430  3.330   -1.604 1.00 32.91 ? ? ? ? ? ? 4   U   B "C3'" 1 
ATOM   223 O "O3'" . U   B 1 4 ? 7.971  4.533   -2.204 1.00 33.77 ? ? ? ? ? ? 4   U   B "O3'" 1 
ATOM   224 C "C2'" . U   B 1 4 ? 7.220  2.456   -1.450 1.00 32.73 ? ? ? ? ? ? 4   U   B "C2'" 1 
ATOM   225 O "O2'" . U   B 1 4 ? 6.575  2.295   -2.680 1.00 33.59 ? ? ? ? ? ? 4   U   B "O2'" 1 
ATOM   226 C "C1'" . U   B 1 4 ? 7.880  1.123   -1.168 1.00 31.65 ? ? ? ? ? ? 4   U   B "C1'" 1 
ATOM   227 N N1    . U   B 1 4 ? 8.145  0.945   0.252  1.00 27.27 ? ? ? ? ? ? 4   U   B N1    1 
ATOM   228 C C2    . U   B 1 4 ? 7.116  0.407   1.004  1.00 26.33 ? ? ? ? ? ? 4   U   B C2    1 
ATOM   229 O O2    . U   B 1 4 ? 6.025  0.144   0.542  1.00 25.01 ? ? ? ? ? ? 4   U   B O2    1 
ATOM   230 N N3    . U   B 1 4 ? 7.433  0.154   2.304  1.00 25.67 ? ? ? ? ? ? 4   U   B N3    1 
ATOM   231 C C4    . U   B 1 4 ? 8.624  0.419   2.932  1.00 25.97 ? ? ? ? ? ? 4   U   B C4    1 
ATOM   232 O O4    . U   B 1 4 ? 8.733  0.189   4.125  1.00 26.89 ? ? ? ? ? ? 4   U   B O4    1 
ATOM   233 C C5    . U   B 1 4 ? 9.638  0.975   2.087  1.00 26.95 ? ? ? ? ? ? 4   U   B C5    1 
ATOM   234 C C6    . U   B 1 4 ? 9.374  1.180   0.799  1.00 26.79 ? ? ? ? ? ? 4   U   B C6    1 
ATOM   235 P P     . A   B 1 5 ? 7.659  5.845   -1.343 1.00 38.00 ? ? ? ? ? ? 5   A   B P     1 
ATOM   236 O OP1   . A   B 1 5 ? 7.568  6.953   -2.309 1.00 45.94 ? ? ? ? ? ? 5   A   B OP1   1 
ATOM   237 O OP2   . A   B 1 5 ? 8.615  5.916   -0.215 1.00 42.36 ? ? ? ? ? ? 5   A   B OP2   1 
ATOM   238 O "O5'" . A   B 1 5 ? 6.189  5.638   -0.801 1.00 32.42 ? ? ? ? ? ? 5   A   B "O5'" 1 
ATOM   239 C "C5'" . A   B 1 5 ? 5.135  5.357   -1.730 1.00 34.53 ? ? ? ? ? ? 5   A   B "C5'" 1 
ATOM   240 C "C4'" . A   B 1 5 ? 3.964  4.766   -1.021 1.00 37.88 ? ? ? ? ? ? 5   A   B "C4'" 1 
ATOM   241 O "O4'" . A   B 1 5 ? 4.378  3.504   -0.416 1.00 39.17 ? ? ? ? ? ? 5   A   B "O4'" 1 
ATOM   242 C "C3'" . A   B 1 5 ? 3.447  5.584   0.166  1.00 41.06 ? ? ? ? ? ? 5   A   B "C3'" 1 
ATOM   243 O "O3'" . A   B 1 5 ? 2.545  6.653   -0.065 1.00 47.91 ? ? ? ? ? ? 5   A   B "O3'" 1 
ATOM   244 C "C2'" . A   B 1 5 ? 2.723  4.521   0.967  1.00 38.28 ? ? ? ? ? ? 5   A   B "C2'" 1 
ATOM   245 O "O2'" . A   B 1 5 ? 1.445  4.177   0.503  1.00 44.36 ? ? ? ? ? ? 5   A   B "O2'" 1 
ATOM   246 C "C1'" . A   B 1 5 ? 3.692  3.350   0.820  1.00 35.39 ? ? ? ? ? ? 5   A   B "C1'" 1 
ATOM   247 N N9    . A   B 1 5 ? 4.687  3.307   1.894  1.00 33.41 ? ? ? ? ? ? 5   A   B N9    1 
ATOM   248 C C8    . A   B 1 5 ? 5.988  3.734   1.910  1.00 28.39 ? ? ? ? ? ? 5   A   B C8    1 
ATOM   249 N N7    . A   B 1 5 ? 6.604  3.495   3.039  1.00 29.70 ? ? ? ? ? ? 5   A   B N7    1 
ATOM   250 C C5    . A   B 1 5 ? 5.635  2.893   3.830  1.00 29.30 ? ? ? ? ? ? 5   A   B C5    1 
ATOM   251 C C6    . A   B 1 5 ? 5.679  2.331   5.118  1.00 27.95 ? ? ? ? ? ? 5   A   B C6    1 
ATOM   252 N N6    . A   B 1 5 ? 6.762  2.354   5.895  1.00 27.76 ? ? ? ? ? ? 5   A   B N6    1 
ATOM   253 N N1    . A   B 1 5 ? 4.545  1.776   5.602  1.00 31.23 ? ? ? ? ? ? 5   A   B N1    1 
ATOM   254 C C2    . A   B 1 5 ? 3.458  1.756   4.819  1.00 33.18 ? ? ? ? ? ? 5   A   B C2    1 
ATOM   255 N N3    . A   B 1 5 ? 3.312  2.200   3.573  1.00 30.12 ? ? ? ? ? ? 5   A   B N3    1 
ATOM   256 C C4    . A   B 1 5 ? 4.455  2.757   3.132  1.00 28.60 ? ? ? ? ? ? 5   A   B C4    1 
ATOM   257 P P     . C   B 1 6 ? 2.653  8.045   0.781  1.00 44.77 ? ? ? ? ? ? 6   C   B P     1 
ATOM   258 O OP1   . C   B 1 6 ? 1.966  9.109   0.001  1.00 53.42 ? ? ? ? ? ? 6   C   B OP1   1 
ATOM   259 O OP2   . C   B 1 6 ? 4.003  8.255   1.300  1.00 43.16 ? ? ? ? ? ? 6   C   B OP2   1 
ATOM   260 O "O5'" . C   B 1 6 ? 1.763  7.753   2.052  1.00 47.65 ? ? ? ? ? ? 6   C   B "O5'" 1 
ATOM   261 C "C5'" . C   B 1 6 ? 0.464  7.236   1.916  1.00 40.88 ? ? ? ? ? ? 6   C   B "C5'" 1 
ATOM   262 C "C4'" . C   B 1 6 ? 0.102  6.583   3.209  1.00 47.07 ? ? ? ? ? ? 6   C   B "C4'" 1 
ATOM   263 O "O4'" . C   B 1 6 ? 1.015  5.499   3.494  1.00 46.03 ? ? ? ? ? ? 6   C   B "O4'" 1 
ATOM   264 C "C3'" . C   B 1 6 ? 0.219  7.445   4.451  1.00 48.06 ? ? ? ? ? ? 6   C   B "C3'" 1 
ATOM   265 O "O3'" . C   B 1 6 ? -0.906 8.255   4.751  1.00 57.60 ? ? ? ? ? ? 6   C   B "O3'" 1 
ATOM   266 C "C2'" . C   B 1 6 ? 0.217  6.396   5.531  1.00 40.63 ? ? ? ? ? ? 6   C   B "C2'" 1 
ATOM   267 O "O2'" . C   B 1 6 ? -1.085 5.914   5.746  1.00 42.08 ? ? ? ? ? ? 6   C   B "O2'" 1 
ATOM   268 C "C1'" . C   B 1 6 ? 1.104  5.334   4.899  1.00 41.87 ? ? ? ? ? ? 6   C   B "C1'" 1 
ATOM   269 N N1    . C   B 1 6 ? 2.514  5.453   5.299  1.00 39.11 ? ? ? ? ? ? 6   C   B N1    1 
ATOM   270 C C2    . C   B 1 6 ? 2.918  4.842   6.492  1.00 32.21 ? ? ? ? ? ? 6   C   B C2    1 
ATOM   271 O O2    . C   B 1 6 ? 2.064  4.299   7.207  1.00 33.98 ? ? ? ? ? ? 6   C   B O2    1 
ATOM   272 N N3    . C   B 1 6 ? 4.205  4.913   6.860  1.00 29.46 ? ? ? ? ? ? 6   C   B N3    1 
ATOM   273 C C4    . C   B 1 6 ? 5.093  5.511   6.066  1.00 32.20 ? ? ? ? ? ? 6   C   B C4    1 
ATOM   274 N N4    . C   B 1 6 ? 6.351  5.526   6.456  1.00 32.12 ? ? ? ? ? ? 6   C   B N4    1 
ATOM   275 C C5    . C   B 1 6 ? 4.716  6.135   4.843  1.00 33.98 ? ? ? ? ? ? 6   C   B C5    1 
ATOM   276 C C6    . C   B 1 6 ? 3.430  6.068   4.492  1.00 32.98 ? ? ? ? ? ? 6   C   B C6    1 
ATOM   277 P P     . A   B 1 7 ? -0.647 9.700   5.329  1.00 58.56 ? ? ? ? ? ? 7   A   B P     1 
ATOM   278 O OP1   . A   B 1 7 ? -1.744 10.593  4.821  1.00 71.37 ? ? ? ? ? ? 7   A   B OP1   1 
ATOM   279 O OP2   . A   B 1 7 ? 0.786  10.061  5.110  1.00 49.02 ? ? ? ? ? ? 7   A   B OP2   1 
ATOM   280 O "O5'" . A   B 1 7 ? -0.619 9.486   6.912  1.00 61.70 ? ? ? ? ? ? 7   A   B "O5'" 1 
ATOM   281 C "C5'" . A   B 1 7 ? -1.507 8.608   7.643  1.00 57.62 ? ? ? ? ? ? 7   A   B "C5'" 1 
ATOM   282 C "C4'" . A   B 1 7 ? -0.925 8.319   9.019  1.00 50.14 ? ? ? ? ? ? 7   A   B "C4'" 1 
ATOM   283 O "O4'" . A   B 1 7 ? 0.090  7.282   8.923  1.00 41.98 ? ? ? ? ? ? 7   A   B "O4'" 1 
ATOM   284 C "C3'" . A   B 1 7 ? -0.157 9.436   9.732  1.00 49.03 ? ? ? ? ? ? 7   A   B "C3'" 1 
ATOM   285 O "O3'" . A   B 1 7 ? -0.841 10.499  10.373 1.00 53.92 ? ? ? ? ? ? 7   A   B "O3'" 1 
ATOM   286 C "C2'" . A   B 1 7 ? 0.540  8.640   10.825 1.00 46.46 ? ? ? ? ? ? 7   A   B "C2'" 1 
ATOM   287 O "O2'" . A   B 1 7 ? -0.225 8.279   11.956 1.00 46.93 ? ? ? ? ? ? 7   A   B "O2'" 1 
ATOM   288 C "C1'" . A   B 1 7 ? 0.972  7.391   10.042 1.00 41.51 ? ? ? ? ? ? 7   A   B "C1'" 1 
ATOM   289 N N9    . A   B 1 7 ? 2.363  7.469   9.579  1.00 33.93 ? ? ? ? ? ? 7   A   B N9    1 
ATOM   290 C C8    . A   B 1 7 ? 2.849  7.997   8.412  1.00 33.35 ? ? ? ? ? ? 7   A   B C8    1 
ATOM   291 N N7    . A   B 1 7 ? 4.156  8.014   8.344  1.00 33.53 ? ? ? ? ? ? 7   A   B N7    1 
ATOM   292 C C5    . A   B 1 7 ? 4.558  7.463   9.551  1.00 31.53 ? ? ? ? ? ? 7   A   B C5    1 
ATOM   293 C C6    . A   B 1 7 ? 5.825  7.154   10.078 1.00 27.99 ? ? ? ? ? ? 7   A   B C6    1 
ATOM   294 N N6    . A   B 1 7 ? 6.973  7.348   9.426  1.00 30.06 ? ? ? ? ? ? 7   A   B N6    1 
ATOM   295 N N1    . A   B 1 7 ? 5.874  6.644   11.325 1.00 30.13 ? ? ? ? ? ? 7   A   B N1    1 
ATOM   296 C C2    . A   B 1 7 ? 4.728  6.440   11.980 1.00 27.37 ? ? ? ? ? ? 7   A   B C2    1 
ATOM   297 N N3    . A   B 1 7 ? 3.482  6.663   11.582 1.00 30.57 ? ? ? ? ? ? 7   A   B N3    1 
ATOM   298 C C4    . A   B 1 7 ? 3.466  7.178   10.343 1.00 31.89 ? ? ? ? ? ? 7   A   B C4    1 
HETATM 299 O O1    . PZG C 2 . ? 10.060 9.877   10.857 1.00 32.53 ? ? ? ? ? ? 101 PZG A O1    1 
HETATM 300 C C1    . PZG C 2 . ? 9.073  9.743   11.593 1.00 30.14 ? ? ? ? ? ? 101 PZG A C1    1 
HETATM 301 N N1    . PZG C 2 . ? 9.333  9.329   12.874 1.00 31.99 ? ? ? ? ? ? 101 PZG A N1    1 
HETATM 302 C C2    . PZG C 2 . ? 8.309  9.150   13.771 1.00 30.05 ? ? ? ? ? ? 101 PZG A C2    1 
HETATM 303 N N2    . PZG C 2 . ? 8.601  8.734   14.964 1.00 27.86 ? ? ? ? ? ? 101 PZG A N2    1 
HETATM 304 N N3    . PZG C 2 . ? 7.084  9.417   13.358 1.00 29.94 ? ? ? ? ? ? 101 PZG A N3    1 
HETATM 305 C C3    . PZG C 2 . ? 6.868  9.864   12.106 1.00 28.72 ? ? ? ? ? ? 101 PZG A C3    1 
HETATM 306 C C4    . PZG C 2 . ? 7.838  10.057  11.231 1.00 28.67 ? ? ? ? ? ? 101 PZG A C4    1 
HETATM 307 N N4    . PZG C 2 . ? 7.291  10.515  10.074 1.00 28.57 ? ? ? ? ? ? 101 PZG A N4    1 
HETATM 308 C C5    . PZG C 2 . ? 6.014  10.623  10.254 1.00 29.73 ? ? ? ? ? ? 101 PZG A C5    1 
HETATM 309 N N5    . PZG C 2 . ? 5.749  10.246  11.519 1.00 31.19 ? ? ? ? ? ? 101 PZG A N5    1 
HETATM 310 C C6    . PZG C 2 . ? 4.456  10.126  12.301 1.00 33.48 ? ? ? ? ? ? 101 PZG A C6    1 
HETATM 311 O O2    . PZG C 2 . ? 3.342  10.148  11.350 1.00 39.24 ? ? ? ? ? ? 101 PZG A O2    1 
HETATM 312 C C7    . PZG C 2 . ? 4.217  11.234  13.309 1.00 35.62 ? ? ? ? ? ? 101 PZG A C7    1 
HETATM 313 O O3    . PZG C 2 . ? 3.219  10.729  14.266 1.00 37.39 ? ? ? ? ? ? 101 PZG A O3    1 
HETATM 314 C C8    . PZG C 2 . ? 3.678  12.346  12.407 1.00 42.05 ? ? ? ? ? ? 101 PZG A C8    1 
HETATM 315 O O4    . PZG C 2 . ? 2.904  13.288  13.115 1.00 37.88 ? ? ? ? ? ? 101 PZG A O4    1 
HETATM 316 C C9    . PZG C 2 . ? 2.729  11.519  11.457 1.00 42.69 ? ? ? ? ? ? 101 PZG A C9    1 
HETATM 317 C C10   . PZG C 2 . ? 2.636  12.168  10.088 1.00 47.40 ? ? ? ? ? ? 101 PZG A C10   1 
HETATM 318 O O5    . PZG C 2 . ? 3.888  12.805  9.758  1.00 54.56 ? ? ? ? ? ? 101 PZG A O5    1 
HETATM 319 P P1    . PZG C 2 . ? 4.132  13.913  8.660  1.00 51.74 ? ? ? ? ? ? 101 PZG A P1    1 
HETATM 320 O O6    . PZG C 2 . ? 3.266  13.132  7.568  1.00 65.99 ? ? ? ? ? ? 101 PZG A O6    1 
HETATM 321 O O7    . PZG C 2 . ? 5.532  13.963  8.224  1.00 65.25 ? ? ? ? ? ? 101 PZG A O7    1 
HETATM 322 C C11   . PZG C 2 . ? 3.672  15.188  9.406  1.00 58.63 ? ? ? ? ? ? 101 PZG A C11   1 
HETATM 323 C C12   . PZG C 2 . ? 4.340  15.501  10.523 1.00 56.35 ? ? ? ? ? ? 101 PZG A C12   1 
HETATM 324 N N6    . PZG C 2 . ? 3.775  16.628  10.973 1.00 65.46 ? ? ? ? ? ? 101 PZG A N6    1 
HETATM 325 N N7    . PZG C 2 . ? 2.706  17.030  10.045 1.00 59.10 ? ? ? ? ? ? 101 PZG A N7    1 
HETATM 326 C C13   . PZG C 2 . ? 2.714  16.078  9.092  1.00 60.52 ? ? ? ? ? ? 101 PZG A C13   1 
HETATM 327 C C14   . PZG C 2 . ? 1.785  16.024  7.859  1.00 60.72 ? ? ? ? ? ? 101 PZG A C14   1 
HETATM 328 O O1    . PZG D 2 . ? 10.938 -8.816  5.799  1.00 30.61 ? ? ? ? ? ? 101 PZG B O1    1 
HETATM 329 C C1    . PZG D 2 . ? 11.175 -8.855  4.617  1.00 32.24 ? ? ? ? ? ? 101 PZG B C1    1 
HETATM 330 N N1    . PZG D 2 . ? 12.473 -8.544  4.284  1.00 31.16 ? ? ? ? ? ? 101 PZG B N1    1 
HETATM 331 C C2    . PZG D 2 . ? 12.876 -8.661  2.966  1.00 26.52 ? ? ? ? ? ? 101 PZG B C2    1 
HETATM 332 N N2    . PZG D 2 . ? 14.109 -8.333  2.700  1.00 25.65 ? ? ? ? ? ? 101 PZG B N2    1 
HETATM 333 N N3    . PZG D 2 . ? 12.050 -9.085  2.007  1.00 24.99 ? ? ? ? ? ? 101 PZG B N3    1 
HETATM 334 C C3    . PZG D 2 . ? 10.761 -9.354  2.347  1.00 31.98 ? ? ? ? ? ? 101 PZG B C3    1 
HETATM 335 C C4    . PZG D 2 . ? 10.308 -9.280  3.648  1.00 33.38 ? ? ? ? ? ? 101 PZG B C4    1 
HETATM 336 N N4    . PZG D 2 . ? 9.041  -9.682  3.655  1.00 29.44 ? ? ? ? ? ? 101 PZG B N4    1 
HETATM 337 C C5    . PZG D 2 . ? 8.698  -9.956  2.412  1.00 30.47 ? ? ? ? ? ? 101 PZG B C5    1 
HETATM 338 N N5    . PZG D 2 . ? 9.757  -9.738  1.604  1.00 32.94 ? ? ? ? ? ? 101 PZG B N5    1 
HETATM 339 C C6    . PZG D 2 . ? 9.782  -9.948  0.152  1.00 35.26 ? ? ? ? ? ? 101 PZG B C6    1 
HETATM 340 O O2    . PZG D 2 . ? 8.518  -10.640 -0.079 1.00 45.18 ? ? ? ? ? ? 101 PZG B O2    1 
HETATM 341 C C7    . PZG D 2 . ? 10.838 -10.941 -0.308 1.00 40.39 ? ? ? ? ? ? 101 PZG B C7    1 
HETATM 342 O O3    . PZG D 2 . ? 11.856 -10.254 -1.053 1.00 36.96 ? ? ? ? ? ? 101 PZG B O3    1 
HETATM 343 C C8    . PZG D 2 . ? 10.128 -11.757 -1.316 1.00 49.76 ? ? ? ? ? ? 101 PZG B C8    1 
HETATM 344 O O4    . PZG D 2 . ? 10.376 -11.121 -2.548 1.00 56.07 ? ? ? ? ? ? 101 PZG B O4    1 
HETATM 345 C C9    . PZG D 2 . ? 8.673  -11.553 -1.175 1.00 50.00 ? ? ? ? ? ? 101 PZG B C9    1 
HETATM 346 C C10   . PZG D 2 . ? 7.993  -12.920 -1.100 1.00 66.29 ? ? ? ? ? ? 101 PZG B C10   1 
HETATM 347 O O5    . PZG D 2 . ? 8.340  -13.561 0.104  1.00 75.98 ? ? ? ? ? ? 101 PZG B O5    1 
HETATM 348 P P1    . PZG D 2 . ? 8.153  -15.177 0.482  1.00 76.84 ? ? ? ? ? ? 101 PZG B P1    1 
HETATM 349 O O6    . PZG D 2 . ? 7.622  -16.167 -0.672 1.00 64.57 ? ? ? ? ? ? 101 PZG B O6    1 
HETATM 350 O O7    . PZG D 2 . ? 7.222  -14.937 1.693  1.00 70.77 ? ? ? ? ? ? 101 PZG B O7    1 
HETATM 351 C C11   . PZG D 2 . ? 10.030 -15.659 0.530  1.00 69.58 ? ? ? ? ? ? 101 PZG B C11   1 
HETATM 352 C C12   . PZG D 2 . ? 10.819 -15.457 -0.537 1.00 63.89 ? ? ? ? ? ? 101 PZG B C12   1 
HETATM 353 N N6    . PZG D 2 . ? 12.042 -15.864 -0.199 1.00 63.79 ? ? ? ? ? ? 101 PZG B N6    1 
HETATM 354 N N7    . PZG D 2 . ? 12.024 -16.346 1.079  1.00 59.30 ? ? ? ? ? ? 101 PZG B N7    1 
HETATM 355 C C13   . PZG D 2 . ? 10.767 -16.213 1.528  1.00 61.66 ? ? ? ? ? ? 101 PZG B C13   1 
HETATM 356 C C14   . PZG D 2 . ? 10.260 -16.633 2.943  1.00 56.52 ? ? ? ? ? ? 101 PZG B C14   1 
HETATM 357 O O     . HOH E 3 . ? 10.411 0.220   8.818  1.00 53.22 ? ? ? ? ? ? 201 HOH A O     1 
HETATM 358 O O     . HOH E 3 . ? -0.925 -12.062 4.403  1.00 36.58 ? ? ? ? ? ? 202 HOH A O     1 
HETATM 359 O O     . HOH F 3 . ? 3.622  -0.631  -0.540 1.00 41.82 ? ? ? ? ? ? 201 HOH B O     1 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1 LCC 1 1 1 LCC LCC A . n 
A 1 2 TLN 2 2 2 TLN LCT A . n 
A 1 3 LCG 3 3 3 LCG LCG A . n 
A 1 4 U   4 4 4 U   U   A . n 
A 1 5 A   5 5 5 A   A   A . n 
A 1 6 C   6 6 6 C   C   A . n 
A 1 7 A   7 7 7 A   A   A . n 
B 1 1 LCC 1 1 1 LCC LCC B . n 
B 1 2 TLN 2 2 2 TLN LCT B . n 
B 1 3 LCG 3 3 3 LCG LCG B . n 
B 1 4 U   4 4 4 U   U   B . n 
B 1 5 A   5 5 5 A   A   B . n 
B 1 6 C   6 6 6 C   C   B . n 
B 1 7 A   7 7 7 A   A   B . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 PZG 1 101 2 PZG PZG A . 
D 2 PZG 1 101 1 PZG PZG B . 
E 3 HOH 1 201 1 HOH HOH A . 
E 3 HOH 2 202 2 HOH HOH A . 
F 3 HOH 1 201 3 HOH HOH B . 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 2670 ? 
1 MORE         15   ? 
1 'SSA (A^2)'  3150 ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_pdbx_version.entry_id 
_pdbx_version.revision_date 
_pdbx_version.major_version 
_pdbx_version.minor_version 
_pdbx_version.revision_type 
_pdbx_version.details 
5HBW 2016-12-07 4 0000 'Initial release' 'Initial release' 
5HBW 2017-01-18 4 0001 Citation          Citation          
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC   ? ? ? 5.8.0049 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? .        2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER   ? ? ? .        4 
# 
loop_
_pdbx_validate_rmsd_bond.id 
_pdbx_validate_rmsd_bond.PDB_model_num 
_pdbx_validate_rmsd_bond.auth_atom_id_1 
_pdbx_validate_rmsd_bond.auth_asym_id_1 
_pdbx_validate_rmsd_bond.auth_comp_id_1 
_pdbx_validate_rmsd_bond.auth_seq_id_1 
_pdbx_validate_rmsd_bond.PDB_ins_code_1 
_pdbx_validate_rmsd_bond.label_alt_id_1 
_pdbx_validate_rmsd_bond.auth_atom_id_2 
_pdbx_validate_rmsd_bond.auth_asym_id_2 
_pdbx_validate_rmsd_bond.auth_comp_id_2 
_pdbx_validate_rmsd_bond.auth_seq_id_2 
_pdbx_validate_rmsd_bond.PDB_ins_code_2 
_pdbx_validate_rmsd_bond.label_alt_id_2 
_pdbx_validate_rmsd_bond.bond_value 
_pdbx_validate_rmsd_bond.bond_target_value 
_pdbx_validate_rmsd_bond.bond_deviation 
_pdbx_validate_rmsd_bond.bond_standard_deviation 
_pdbx_validate_rmsd_bond.linker_flag 
1 1 "O3'" A TLN 2 ? ? P A LCG 3 ? ? 1.681 1.607 0.074  0.012 Y 
2 1 "O3'" A C   6 ? ? P A A   7 ? ? 1.529 1.607 -0.078 0.012 Y 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1  1 "C3'" A LCC 1 ? ? "O3'" A LCC 1 ? ? P     A TLN 2 ? ? 127.41 119.70 7.71   1.20 Y 
2  1 "O3'" A TLN 2 ? ? P     A LCG 3 ? ? "O5'" A LCG 3 ? ? 91.26  104.00 -12.74 1.90 Y 
3  1 "C3'" A LCG 3 ? ? "O3'" A LCG 3 ? ? P     A U   4 ? ? 127.68 119.70 7.98   1.20 Y 
4  1 "C3'" B LCC 1 ? ? "O3'" B LCC 1 ? ? P     B TLN 2 ? ? 142.09 119.70 22.39  1.20 Y 
5  1 "O3'" B LCC 1 ? ? P     B TLN 2 ? ? "O5'" B TLN 2 ? ? 85.04  104.00 -18.96 1.90 Y 
6  1 "O3'" B LCC 1 ? ? P     B TLN 2 ? ? OP2   B TLN 2 ? ? 117.34 110.50 6.84   1.10 Y 
7  1 "O3'" B TLN 2 ? ? P     B LCG 3 ? ? "O5'" B LCG 3 ? ? 82.92  104.00 -21.08 1.90 Y 
8  1 "O3'" B TLN 2 ? ? P     B LCG 3 ? ? OP2   B LCG 3 ? ? 129.04 110.50 18.54  1.10 Y 
9  1 "O3'" B LCG 3 ? ? P     B U   4 ? ? OP2   B U   4 ? ? 129.20 110.50 18.70  1.10 Y 
10 1 "O3'" B LCG 3 ? ? P     B U   4 ? ? OP1   B U   4 ? ? 86.60  105.20 -18.60 2.20 Y 
11 1 "O5'" B A   7 ? ? P     B A   7 ? ? OP2   B A   7 ? ? 99.25  105.70 -6.45  0.90 N 
# 
_ndb_struct_conf_na.entry_id   5HBW 
_ndb_struct_conf_na.feature    'a-form double helix' 
# 
loop_
_ndb_struct_na_base_pair.model_number 
_ndb_struct_na_base_pair.i_label_asym_id 
_ndb_struct_na_base_pair.i_label_comp_id 
_ndb_struct_na_base_pair.i_label_seq_id 
_ndb_struct_na_base_pair.i_symmetry 
_ndb_struct_na_base_pair.j_label_asym_id 
_ndb_struct_na_base_pair.j_label_comp_id 
_ndb_struct_na_base_pair.j_label_seq_id 
_ndb_struct_na_base_pair.j_symmetry 
_ndb_struct_na_base_pair.shear 
_ndb_struct_na_base_pair.stretch 
_ndb_struct_na_base_pair.stagger 
_ndb_struct_na_base_pair.buckle 
_ndb_struct_na_base_pair.propeller 
_ndb_struct_na_base_pair.opening 
_ndb_struct_na_base_pair.pair_number 
_ndb_struct_na_base_pair.pair_name 
_ndb_struct_na_base_pair.i_auth_asym_id 
_ndb_struct_na_base_pair.i_auth_seq_id 
_ndb_struct_na_base_pair.i_PDB_ins_code 
_ndb_struct_na_base_pair.j_auth_asym_id 
_ndb_struct_na_base_pair.j_auth_seq_id 
_ndb_struct_na_base_pair.j_PDB_ins_code 
_ndb_struct_na_base_pair.hbond_type_28 
_ndb_struct_na_base_pair.hbond_type_12 
1 A TLN 2 1_555 B A   7 1_555 -0.079 -0.065 0.143  -2.521 -10.003 3.393  1 A_TLN2:A7_B A 2 ? B 7 ? 20 1 
1 A LCG 3 1_555 B C   6 1_555 -0.411 -0.131 -0.032 -4.333 -16.933 0.480  2 A_LCG3:C6_B A 3 ? B 6 ? 19 1 
1 A U   4 1_555 B A   5 1_555 0.084  -0.155 0.224  -4.909 -16.471 -0.481 3 A_U4:A5_B   A 4 ? B 5 ? 20 1 
1 A A   5 1_555 B U   4 1_555 0.013  -0.154 -0.015 1.198  -10.587 0.973  4 A_A5:U4_B   A 5 ? B 4 ? 20 1 
1 A C   6 1_555 B LCG 3 1_555 0.413  -0.269 -0.075 7.750  -16.725 -2.129 5 A_C6:LCG3_B A 6 ? B 3 ? 19 1 
1 A A   7 1_555 B TLN 2 1_555 0.045  0.009  -0.046 4.373  -13.206 1.929  6 A_A7:TLN2_B A 7 ? B 2 ? 20 1 
# 
loop_
_ndb_struct_na_base_pair_step.model_number 
_ndb_struct_na_base_pair_step.i_label_asym_id_1 
_ndb_struct_na_base_pair_step.i_label_comp_id_1 
_ndb_struct_na_base_pair_step.i_label_seq_id_1 
_ndb_struct_na_base_pair_step.i_symmetry_1 
_ndb_struct_na_base_pair_step.j_label_asym_id_1 
_ndb_struct_na_base_pair_step.j_label_comp_id_1 
_ndb_struct_na_base_pair_step.j_label_seq_id_1 
_ndb_struct_na_base_pair_step.j_symmetry_1 
_ndb_struct_na_base_pair_step.i_label_asym_id_2 
_ndb_struct_na_base_pair_step.i_label_comp_id_2 
_ndb_struct_na_base_pair_step.i_label_seq_id_2 
_ndb_struct_na_base_pair_step.i_symmetry_2 
_ndb_struct_na_base_pair_step.j_label_asym_id_2 
_ndb_struct_na_base_pair_step.j_label_comp_id_2 
_ndb_struct_na_base_pair_step.j_label_seq_id_2 
_ndb_struct_na_base_pair_step.j_symmetry_2 
_ndb_struct_na_base_pair_step.shift 
_ndb_struct_na_base_pair_step.slide 
_ndb_struct_na_base_pair_step.rise 
_ndb_struct_na_base_pair_step.tilt 
_ndb_struct_na_base_pair_step.roll 
_ndb_struct_na_base_pair_step.twist 
_ndb_struct_na_base_pair_step.x_displacement 
_ndb_struct_na_base_pair_step.y_displacement 
_ndb_struct_na_base_pair_step.helical_rise 
_ndb_struct_na_base_pair_step.inclination 
_ndb_struct_na_base_pair_step.tip 
_ndb_struct_na_base_pair_step.helical_twist 
_ndb_struct_na_base_pair_step.step_number 
_ndb_struct_na_base_pair_step.step_name 
_ndb_struct_na_base_pair_step.i_auth_asym_id_1 
_ndb_struct_na_base_pair_step.i_auth_seq_id_1 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.j_auth_asym_id_1 
_ndb_struct_na_base_pair_step.j_auth_seq_id_1 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.i_auth_asym_id_2 
_ndb_struct_na_base_pair_step.i_auth_seq_id_2 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_2 
_ndb_struct_na_base_pair_step.j_auth_asym_id_2 
_ndb_struct_na_base_pair_step.j_auth_seq_id_2 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_2 
1 A TLN 2 1_555 B A   7 1_555 A LCG 3 1_555 B C   6 1_555 -0.223 -1.871 3.221 0.271  8.970  27.102 -5.630 0.507 2.484 18.509 
-0.560 28.523 1 AA_TLN2LCG3:C6A7_BB A 2 ? B 7 ? A 3 ? B 6 ? 
1 A LCG 3 1_555 B C   6 1_555 A U   4 1_555 B A   5 1_555 -0.322 -1.438 3.259 -3.361 5.140  34.347 -3.156 0.043 3.036 8.619  5.636 
34.876 2 AA_LCG3U4:A5C6_BB   A 3 ? B 6 ? A 4 ? B 5 ? 
1 A U   4 1_555 B A   5 1_555 A A   5 1_555 B U   4 1_555 -0.231 -1.250 3.040 0.657  6.576  31.866 -3.256 0.515 2.729 11.819 
-1.181 32.527 3 AA_U4A5:U4A5_BB     A 4 ? B 5 ? A 5 ? B 4 ? 
1 A A   5 1_555 B U   4 1_555 A C   6 1_555 B LCG 3 1_555 -0.136 -0.931 3.087 0.660  8.112  33.142 -2.761 0.327 2.785 13.961 
-1.135 34.100 4 AA_A5C6:LCG3U4_BB   A 5 ? B 4 ? A 6 ? B 3 ? 
1 A C   6 1_555 B LCG 3 1_555 A A   7 1_555 B TLN 2 1_555 -0.091 -1.530 3.311 -0.440 14.636 28.272 -5.223 0.094 2.265 27.735 0.834 
31.770 5 AA_C6A7:TLN2LCG3_BB A 6 ? B 3 ? A 7 ? B 2 ? 
# 
_pdbx_audit_support.funding_organization   'Howard Hughes Medical Institute' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 
;[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-(3-methyl-1~{H}-pyrazol-4-yl)phosphinic acid
;
PZG 
3 water HOH 
# 
