BMRB Entry 11078
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PDB ID: 2z5v
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR11078
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Title: Solution structure of the TIR domain of human MyD88 PubMed: 19506249
Deposition date: 2009-09-11 Original release date: 2010-03-12
Authors: Ohnishi, H.; Tochio, H.; Hiroaki, H.; Kondo, N.; Kato, Z.; Shirakawa, M.
Citation: Ohnishi, Hidenori; Tochio, Hidehito; Kato, Zenichiro; Orii, Kenji; Li, Ailian; Kimura, Takeshi; Hiroaki, Hidekazu; Kondo, Naomi; Shirakawa, Masahiro. "Structural basis for the multiple interactions of the MyD88 TIR domain in TLR4 signaling." Proc. Natl. Acad. Sci. U.S.A. 106, 10260-10265 (2009).
Assembly members:
MyD88 TIR domain, polymer, 149 residues, 17387.422 Da.
Natural source: Common Name: human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
MyD88 TIR domain: TTLDDPLGHMPERFDAFICY
CPSDIQFVQEMIRQLEQTNY
RLKLCVSDRDVLPGTCVWSI
ASELIEKRCRRMVVVVSDDY
LQSKECDFQTKFALSLSPGA
HQKRLIPIKYKAMKKEFPSI
LRFITVCDYTNPCTKSWFWT
RLAKALSLP
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 454 |
| 15N chemical shifts | 134 |
| 1H chemical shifts | 850 |
Additional metadata:
Related Database Links:
| BMRB | 15356 |
| PDB | 2JS7 2Z5V 4EO7 |
| DBJ | BAE89833 BAG55247 BAG55248 BAG55249 BAG55250 |
| GB | AAB49967 AAC50954 AAH13589 AAP36040 AAP36509 |
| REF | NP_001123935 NP_001124153 NP_001166039 NP_001266118 NP_001266529 |
| SP | B3Y678 B3Y679 B3Y680 B3Y681 B3Y682 |
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