BMRB Entry 11504
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PDB ID: 2rt5
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR11504
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Title: Structure of SPOC domain of the human transcriptional corepressor SHARP PubMed: 24268649
Deposition date: 2012-05-22 Original release date: 2013-12-02
Authors: Mikami, Suzuka; Kanaba, Teppei; Mishima, Masaki
Citation: Mikami, Suzuka; Kanaba, Teppei; Mishima, Masaki. "Structural Insights into the Recruitment of SMRT by the Corepressor SHARP under Phosphorylative Regulation" Structure ., .-. (2013).
Assembly members:
SHARP, polymer, 169 residues, 18471.535 Da.
SMRT, polymer, 8 residues, 1102.889 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
SHARP: VDMVQLLKKYPIVWQGLLAL
KNDTAAVQLHFVSGNNVLAH
RSLPLSEGGPPLRIAQRMRL
EATQLEGVARRMTVETDYCL
LLALPCGRDQEDVVSQTESL
KAAFITYLQAKQAAGIINVP
NPGSNQPAYVLQIFPPCEFS
ESHLSRLAPDLLASISNISP
HLMIVIASV
SMRT: YETLXDXE
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 723 |
| 15N chemical shifts | 163 |
| 1H chemical shifts | 1137 |
Additional metadata:
Related Database Links:
| PDB | 1OW1 2RT5 |
| DBJ | BAA76773 BAB32786 BAG10400 |
| EMBL | CAB51072 |
| GB | AAD55931 AAI72907 AAK52750 EAW51756 EDL80993 |
| REF | NP_001258424 NP_055816 NP_062737 XP_002694185 XP_002750362 |
| SP | Q62504 Q96T58 |
| TPG | DAA21211 |
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