BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
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BMRB Entry 15124

Title: Discovery and optimization of a natural HIV-1 entry inhibitor targeting the gp41 fusion peptide   PubMed: 17448989

Deposition date: 2007-02-01 Original release date: 2007-05-21

Authors: Munch, Jan; Standker, Ludger; Adermann, Knut; Schulz, Axel; Pohlmann, Stefan; Chaipan, Chawaree; Biet, Thorsten; Peters, Thomas; Meyer, Bernd; Wilhelm, Dennis; Lu, Hong; Jing, Weiguo; Jiang, Shibo; Forssmann, Wolf-Georg; Kirchhoff, Frank

Citation: Munch, Jan; Standker, Ludger; Adermann, Knut; Schulz, Axel; Schindler, M.; Chinnadurai, R.; Pohlmann, Stefan; Chaipan, Chawaree; Biet, Thorsten; Peters, Thomas; Meyer, Bernd; Wilhelm, Dennis; Lu, Hong; Jing, Weiguo; Jiang, Shibo; Forssmann, Wolf-Georg; Kirchhoff, Frank. "Discovery and optimization of a natural HIV-1 entry inhibitor targeting the gp41 fusion peptide"  Cell 129, 263-275 (2007).

Assembly members:
VIR165, polymer, 20 residues, Formula weight is not available
FP1-23, polymer, 23 residues, 2125.487 Da.

Natural source:   Common Name: human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):
VIR165: LEAIPCSIPPCFAFNKPFVF
FP1-23: AVGIGALFLGFLGAAGSTMG ARS

Data sets:
Data typeCount
1H chemical shifts218

Additional metadata:

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  • Samples and Experiments
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Related Database Links:

PDB 2JNR 1ERF 1P5A
EMBL CAA82777 CAA82778 CAA82780
GB AAA96326 AAB03749 AAB17030 AAB59751 AAB68317
SP P03377 P20871