BMRB Entry 15306
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PDB ID: 2jqz
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_anomalous, AVS_full, LACS, SPARTA
BMRB Entry DOI: doi:10.13018/BMR15306
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Title: Solution Structure of the C2 domain of human Smurf2 PubMed: 17719543
Deposition date: 2007-06-15 Original release date: 2008-02-28
Authors: Wiesner, Silke; Ogunjimi, Abiodun; Wang, Hong-Rui; Rotin, Daniela; Sicheri, Frank; Wrana, Jeff; Forman-Kay, Julie
Citation: Wiesner, Silke; Ogunjimi, Abiodun; Wang, Hong-Rui; Rotin, Daniela; Sicheri, Frank; Wrana, Jeff; Forman-Kay, Julie. "Auto-inhibition of the HECT-type ubiquitin ligase Smurf2 through its C2 domain" Cell 130, 651-662 (2007).
Assembly members:
C2 domain of Smurf2, polymer, 131 residues, 14707.108 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
C2 domain of Smurf2: GPVKLRLTVLCAKNLVKKDF
FRLPDPFAKVVVDGSGQCHS
TDTVKNTLDPKWNQHYDLYI
GKSDSVTISVWNHKKIHKKQ
GAGFLGCVRLLSNAINRLKD
TGYQRLDLCKLGPNDNDTVR
GQIVVSLQSRD
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 433 |
| 15N chemical shifts | 138 |
| 1H chemical shifts | 864 |
Additional metadata:
Related Database Links:
| PDB | 2JQZ |
| DBJ | BAG11417 |
| EMBL | CDQ73842 |
| GB | AAG25641 AAG45422 AAG50421 AAG50422 AAH93876 |
| REF | NP_001082282 NP_001100531 NP_073576 NP_079757 XP_002186702 |
| SP | A2A5Z6 Q2TAS2 Q9HAU4 |
| TPG | DAA18293 |
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