BMRB Entry 16173
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PDB ID: 2kfb
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_anomalous, AVS_full, LACS, SPARTA
BMRB Entry DOI: doi:10.13018/BMR16173
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Title: The structure of the cataract causing P23T mutant of human gamma-D crystallin PubMed: 19216553
Deposition date: 2009-02-12 Original release date: 2009-03-05
Authors: Jung, Jinwon; Byeon, In-Ja; Wang, Yongting; King, Jonathan; Gronenborn, Angela
Citation: Jung, Jinwon; Byeon, In-Ja; Wang, Yongting; King, Jonathan; Gronenborn, Angela. "The structure of the cataract causing P23T mutant of HgD crystallin exhibits local distinctive conformational and dynamic changes." Biochemistry 48, 2597-2609 (2009).
Assembly members:
p23t, polymer, 182 residues, Formula weight is not available
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
p23t: MKHHHHHHQGKITLYEDRGF
QGRHYECSSDHTNLQPYLSR
CNSARVDSGCWMLYEQPNYS
GLQYFLRRGDYADHQQWMGL
SDSVRSCRLIPHSGSHRIRL
YEREDYRGQMIEFTEDCSCL
QDRFRFNEIHSLNVLEGSWV
LYELSNYRGRQYLLMPGDYR
RYQDWGATNARVGSLRRVID
FS
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 678 |
| 15N chemical shifts | 191 |
| 1H chemical shifts | 1149 |
Additional metadata:
Related Database Links:
| PDB | 1H4A 1HK0 2G98 2KFB 2KLJ 4GR7 4JGF |
| GB | AAA52112 AAB38686 AAI17339 AAI17341 AAY24041 |
| REF | NP_001129137 NP_008822 XP_003820863 XP_004033174 |
| SP | P07320 |
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