BMRB Entry 17323
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PDB ID: 2l6u
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR17323
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Title: Solution NMR Structure of Med25(391-543) Comprising the Activator-Interacting Domain (ACID) of Human Mediator Subuniti 25. Northeast Structural Genomics Consortium Target HR6188A PubMed: 21785987
Deposition date: 2010-11-24 Original release date: 2010-12-22
Authors: Eletsky, Alexander; Ryuechan, William; Sukumaran, Dinesh; Shastry, Ritu; Ciccosanti, Colleen; Janjua, Haleema; Acton, Thomas; Xiao, Rong; Everett, John; Montelione, Gaetano; Szyperski, Thomas
Citation: Eletsky, Alexander; Ruyechan, William; Xiao, Rong; Acton, Thomas; Montelione, Gaetano; Szyperski, Thomas. "Solution NMR structure of MED25(391-543) comprising the activator-interacting domain (ACID) of human mediator subunit 25." J. Struct. Funct. Genomics 12, 159-166 (2011).
Assembly members:
HR6188A, polymer, 163 residues, 18637.756 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
HR6188A: MGHHHHHHSHGQQSVSNKLL
AWSGVLEWQEKPKPASVDAN
TKLTRSLPCQVYVNHGENLK
TEQWPQKLIMQLIPQQLLTT
LGPLFRNSRMVQFHFTNKDL
ESLKGLYRIMGNGFAGCVHF
PHTAPCEVRVLMLLYSSKKK
IFMGLIPYDQSGFVNGIRQV
ITN
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 721 |
| 15N chemical shifts | 172 |
| 1H chemical shifts | 1160 |
Additional metadata:
Related Database Links:
| BMRB | 17139 |
| PDB | 2KY6 2L23 2L6U 2XNF |
| DBJ | BAE29135 BAF82149 BAG51583 BAG61008 |
| EMBL | CAB66680 CAE84581 |
| GB | AAG15589 AAH21333 AAH24312 AAH31138 AAH65297 |
| REF | NP_001075914 NP_001163897 NP_083641 NP_112235 XP_001115473 |
| SP | A2VE44 Q71SY5 Q8VCB2 |
| TPG | DAA19611 |
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