BMRB Entry 17478
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PDB ID: 2l9m
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR17478
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Title: Structure of cIAP1 CARD PubMed: 21549626
Deposition date: 2011-02-21 Original release date: 2011-05-12
Authors: Hinds, Mark; Rautureau, Gilles; Day, Catherine
Citation: Lopez, Juanita; John, Sidonie Wicky; Tenev, Tencho; Rautureau, Gilles; Hinds, Mark; Francalanci, Floriana; Wilson, Rebecca; Broemer, Meike; Santoro, Massimo; Day, Catherine; Meier, Pascal. "CARD-Mediated Autoinhibition of cIAP1's E3 Ligase Activity Suppresses Cell Proliferation and Migration." Mol. Cell 42, 569-583 (2011).
Assembly members:
cIAP1-CARD, polymer, 132 residues, 15147.519 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
cIAP1-CARD: GSHMLNAEDEKREEEKEKQA
EEMASDDLSLIRKNRMALFQ
QLTCVLPILDNLLKANVINK
QEHDIIKQKTQIPLQARELI
DTILVKGNAAANIFKNCLKE
IDSTLYKNLFVDKNMKYIPT
EDVSGLSLEEQL
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 156 |
| 15N chemical shifts | 149 |
| 1H chemical shifts | 165 |
Additional metadata:
Related Database Links:
| PDB | 2L9M 3T6P |
| DBJ | BAG10600 BAG36235 BAG64288 |
| EMBL | CAH91479 |
| GB | AAC41942 AAC50372 AAC50508 AAH16174 AAH28578 |
| PRF | 2205253A |
| REF | NP_001157 NP_001243092 NP_001243095 NP_001248250 XP_001152534 |
| SP | Q13490 |
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