BMRB Entry 17544
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PDB ID: 2lb2
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_anomalous, AVS_full
BMRB Entry DOI: doi:10.13018/BMR17544
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Title: Structure of the second domain of human Nedd4L in complex with a doubly phosphorylated human Smad3 derived peptide. PubMed: 21685363
Deposition date: 2011-03-22 Original release date: 2011-06-23
Authors: Macias, Maria; Aragon, Eric; Goerner, Nina; Zaromytidou, Alexia-Ileana; Xi, Qiaoran; Escobedo, Albert; Massague, Joan
Citation: Aragon, Eric; Goerner, Nina; Zaromytidou, Alexia-Ileana; Xi, Qiaoran; Escobedo, Albert; Massague, Joan; Macias, Maria. "A Smad action turnover switch operated by WW domain readers of a phosphoserine code." Genes Dev. 25, 1275-1288 (2011).
Assembly members:
second domain of human Nedd4L, polymer, 35 residues, 4184.715 Da.
doubly phosphorylated human Smad3, polymer, 12 residues, 1341.284 Da.
Natural source: Common Name: human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
second domain of human Nedd4L: GLPSGWEERKDAKGRTYYVN
HNNRTTTWTRPIMQL
doubly phosphorylated human Smad3: EXPPPGYLSEDG
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 98 |
| 15N chemical shifts | 33 |
| 1H chemical shifts | 313 |
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