BMRB Entry 17752
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PDB ID: 2lfg
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_anomalous, AVS_full, LACS, SPARTA
BMRB Entry DOI: doi:10.13018/BMR17752
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Title: SOLUTION STRUCTURE OF THE HUMAN PROLACTIN RECEPTOR ECD DOMAIN D2
Deposition date: 2011-06-30 Original release date: 2012-02-13
Authors: Dagil, Robert; Knudsen, Maiken; Kragelund, Birthe; O'Shea, Charlotte
Citation: Dagil, Robert; Knudsen, Maiken; Olsen, Johan; O'Shea, Charlotte; Franzmann, Magnus; Goffin, Vincent; Teilum, Kaare; Breinholt, Jens; Kragelund, Birthe. "The WSXWS Motif in Cytokine Receptors Is a Molecular Switch Involved in Receptor Activation: Insight from Structures of the Prolactin Receptor" Structure 20, 270-282 (2012).
Assembly members:
hPRLR-D2, polymer, 113 residues, 13328.4 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
hPRLR-D2: MYIVQPDPPLELAVEVKQPE
DRKPYLWIKWSPPTLIDLKT
GWFTLLYEIRLKPEKAAEWE
IHFAGQQTEFKILSLHPGQK
YLVQVRCKPDHGYWSAWSPA
TFIQIPSDFTMND
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 549 |
| 15N chemical shifts | 112 |
| 1H chemical shifts | 809 |
Additional metadata:
Related Database Links:
| PDB | 1BP3 2LFG 3D48 3MZG 3N06 3N0P 3NCB 3NCC 3NCE 3NCF 4I18 |
| DBJ | BAG36079 BAG73583 |
| EMBL | CAH91100 CAL38328 CAL38451 |
| GB | AAA60174 AAB34470 AAD32032 AAD49855 AAH59392 |
| REF | NP_000940 NP_001153263 NP_001191243 NP_001191244 NP_001191245 |
| SP | P16471 |
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