BMRB Entry 17878
Chem Shift validation: AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR17878
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Title: Backbone 1H, 13C, and 15N Chemical Shift Assignments for La(4-325) PubMed: 22009680
Deposition date: 2011-08-22 Original release date: 2011-12-09
Authors: Martino, Luigi; Kelly, Geoff; Curry, Stephen; Conte, Maria
Citation: Martino, Luigi; Pennell, Simon; Kelly, Geoff; Bui, Tam; Kotik-Kogan, Olga; Smerdon, Stephen; Drake, Alex; Curry, Stephen; Conte, Maria. "Analysis of the interaction with the hepatitis C virus mRNA reveals an alternative mode of RNA recognition by the human La protein." Nucleic Acids Res. 40, 1381-1394 (2012).
Assembly members:
human_La_protein, polymer, 322 residues, 37441.7 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
human_La_protein: NGDNEKMAALEAKICHQIEY
YFGDFNLPRDKFLKEQIKLD
EGWVPLEIMIKFNRLNRLTT
DFNVIVEALSKSKAELMEIS
EDKTKIRRSPSKPLPEVTDE
YKNDVKNRSVYIKGFPTDAT
LDDIKEWLEDKGQVLNIQMR
RTLHKAFKGSIFVVFDSIES
AKKFVETPGQKYKETDLLIL
FKDDYFAKKNEERKQNKVEA
KLRAKQEQEAKQKLEEDAEM
KSLEEKIGCLLKFSGDLDDQ
TCREDLHILFSNHGEIKWID
FVRGAKEGIILFKEKAKEAL
GKAKDANNGNLQLRNKEVTW
EVLEGEVEKEALKKIIEDQQ
ES
- assigned_chemical_shifts
Data type | Count |
13C chemical shifts | 687 |
15N chemical shifts | 260 |
1H chemical shifts | 260 |
Additional metadata:
Related Database Links:
BMRB | 15726 15727 |
PDB | 1YTY 1ZH5 2VOD 2VON 2VOO 2VOP |
DBJ | BAE87871 BAE87890 BAG70042 BAG70165 BAI45822 |
EMBL | CAA31985 CAA32815 |
GB | AAA36577 AAA51885 AAH01289 AAH20818 AAP88864 |
REF | NP_001267347 NP_001270975 NP_001281074 NP_001296114 NP_003133 |
SP | P05455 |
Download simulated HSQC data in one of the following formats:
CSV: Backbone
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SPARKY: Backbone
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