BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
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BMRB Entry 17878

Title: Backbone 1H, 13C, and 15N Chemical Shift Assignments for La(4-325)   PubMed: 22009680

Deposition date: 2011-08-22 Original release date: 2011-12-09

Authors: Martino, Luigi; Kelly, Geoff; Curry, Stephen; Conte, Maria

Citation: Martino, Luigi; Pennell, Simon; Kelly, Geoff; Bui, Tam; Kotik-Kogan, Olga; Smerdon, Stephen; Drake, Alex; Curry, Stephen; Conte, Maria. "Analysis of the interaction with the hepatitis C virus mRNA reveals an alternative mode of RNA recognition by the human La protein."  Nucleic Acids Res. 40, 1381-1394 (2012).

Assembly members:
human_La_protein, polymer, 322 residues, 37441.7 Da.

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli

Entity Sequences (FASTA):
human_La_protein: NGDNEKMAALEAKICHQIEY YFGDFNLPRDKFLKEQIKLD EGWVPLEIMIKFNRLNRLTT DFNVIVEALSKSKAELMEIS EDKTKIRRSPSKPLPEVTDE YKNDVKNRSVYIKGFPTDAT LDDIKEWLEDKGQVLNIQMR RTLHKAFKGSIFVVFDSIES AKKFVETPGQKYKETDLLIL FKDDYFAKKNEERKQNKVEA KLRAKQEQEAKQKLEEDAEM KSLEEKIGCLLKFSGDLDDQ TCREDLHILFSNHGEIKWID FVRGAKEGIILFKEKAKEAL GKAKDANNGNLQLRNKEVTW EVLEGEVEKEALKKIIEDQQ ES

Data sets:
Data typeCount
13C chemical shifts687
15N chemical shifts260
1H chemical shifts260

Additional metadata:

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  • Samples and Experiments
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  • Spectrometers
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Related Database Links:

BMRB 15726 15727
PDB 1YTY 1ZH5 2VOD 2VON 2VOO 2VOP
DBJ BAE87871 BAE87890 BAG70042 BAG70165 BAI45822
EMBL CAA31985 CAA32815
GB AAA36577 AAA51885 AAH01289 AAH20818 AAP88864
REF NP_001267347 NP_001270975 NP_001281074 NP_001296114 NP_003133
SP P05455

Download simulated HSQC data in one of the following formats:
CSV: Backbone or all simulated shifts
SPARKY: Backbone or all simulated shifts