BMRB Entry 18094
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PDB ID: 2lm0
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR18094
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Title: Solution structure of the AF4-AF9 complex PubMed: 23260655
Deposition date: 2011-11-18 Original release date: 2013-01-07
Authors: Leach, Benjamin; Lumba, Bhavna; Chang, Ming-Jin; Cierpicki, Tomasz; Johnson, Stephanie; Hemenway, Charles; Bushweller, John
Citation: Leach, Benjamin; Kuntimaddi, Aravinda; Schmidt, Charles; Cierpicki, Tomasz; Johnson, Stephanie; Bushweller, John. "Leukemia Fusion Target AF9 Is an Intrinsically Disordered Transcriptional Regulator that Recruits Multiple Partners via Coupled Folding and Binding." Structure 21, 176-183 (2013).
Assembly members:
AF4-Af9 fusion, polymer, 125 residues, 9252.518 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
AF4-Af9 fusion: TRLPLPLRDTKLLSPLRDTP
PPQSLMVKITLDLLSRIPQP
PGKPMGSDKQIKNGECDKAY
LDELVELHRRLMTLRERHIL
QQIVNLIEETGHFHITNTTF
DFDLCSLDKTTVRKLQSYLE
TSGTS
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 446 |
| 15N chemical shifts | 108 |
| 1H chemical shifts | 731 |
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