BMRB Entry 18099
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PDB ID: 2lm5
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS, SPARTA
BMRB Entry DOI: doi:10.13018/BMR18099
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Title: Solution structure of Ca2+-CIB1 in complex with the cytoplasmic domain of the integrin aIIb subunit PubMed: 22283712
Deposition date: 2011-11-22 Original release date: 2012-02-01
Authors: Huang, Hao; Vogel, Hans
Citation: Huang, Hao; Vogel, Hans. "Structural basis for the activation of platelet integrin IIb3 by calcium- and integrin-binding protein 1." J. Am. Chem. Soc. 134, 3864-3872 (2012).
Assembly members:
CIB1, polymer, 214 residues, 21093.814 Da.
CA, non-polymer, 40.078 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
CIB1: MGHHHHHHHHHHSSGHIDDD
DKHMGGSGSRLSKELLAEYQ
DLTFLTKQEILLAHRRFCEL
LPQEQRSVESSLRAQVPFEQ
ILSLPELKANPFKERICRVF
STSPAKDSLSFEDFLDLLSV
FSDTATPDIKSHYAFRIFDF
DDDGTLNREDLSRLVNCLTG
EGEDTRLSASEMKQLIDNIL
EESDIDRDGTINLSEFQHVI
SRSPDFASSFKIVL
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 591 |
| 15N chemical shifts | 159 |
| 1H chemical shifts | 369 |
Additional metadata:
Related Database Links:
| BMRB | 17328 17329 |
| PDB | 1DGU 1DGV 1XO5 1Y1A 2L4H 2L4I 2LM5 |
| DBJ | BAA36281 BAG70090 BAG70220 BAG72967 |
| EMBL | CAG33236 |
| GB | AAB39758 AAB53387 AAC51106 AAH00846 ABM82122 |
| REF | NP_006375 XP_001096008 XP_003268547 XP_003807774 XP_003901434 |
| SP | Q99828 |
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