BMRB Entry 18205
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PDB ID: 2lob
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS, SPARTA
BMRB Entry DOI: doi:10.13018/BMR18205
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Title: PDZ Domain of CAL (Cystic Fibrosis Transmembrane Regulator-Associated Ligand) PubMed: 16331976
Deposition date: 2012-01-20 Original release date: 2012-03-02
Authors: Piserchio, Andrea; Fellows, Abigail; Maden, Dean; Mierke, Dale
Citation: Piserchio, Andrea; Fellows, Abigail; Madden, Dean; Mierke, Dale. "Association of the cystic fibrosis transmembrane regulator with CAL: structural features and molecular dynamics." Biochemistry 44, 16158-16166 (2005).
Assembly members:
PDZ Domain of CAL, polymer, 112 residues, 9256.696 Da.
C-terminus of the CFTR, polymer, 8 residues, 990.055 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
PDZ Domain of CAL: HHHHHHHHHHSSGHIEGRHM
ENLYFQGIRKVLLLKEDHEG
LGISITGGKEHGVPILISEI
HPGQPADRCGGLHVGDAILA
VNGVNLRDTKHKEAVTILSQ
QRGEIEFEVVYV
C-terminus of the CFTR: EEVQDTRL
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 222 |
| 15N chemical shifts | 79 |
Additional metadata:
Related Database Links:
| UNP | Q9HD26-2 P13569-1 |
| PDB | 2DC2 2LOB 4E34 4E35 4JOE 4JOF 4JOG 4JOH 4JOJ 4JOK 4JOP 4JOR 4K6Y 4K72 4K75 4K76 4K78 4Q6H 4Q6S |
| DBJ | BAB69946 BAC26958 BAC27058 BAC27951 |
| EMBL | CAH90325 |
| GB | AAG00571 AAG00572 AAH09553 AAH51171 AAI68160 |
| PRF | 1611455A |
| REF | NP_001017408 NP_001101101 NP_001125151 NP_001186201 NP_001193086 |
| SP | Q5RD32 Q8BH60 Q9HD26 |
| TPG | DAA26316 DAA26317 |