BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
Member of WWPDB

BMRB Entry 18378

Title: Liraglutide

Deposition date: 2012-04-03 Original release date: 2013-07-08

Authors: Ludvigsen, Svend; Steensgaard, D.; Thomsen, J.; Strauss, H.; Normann, M.

Citation: Steensgaard, D.; Thomsen, J.; Strauss, H.; Normann, M.; Ludvigsen, Svend. "unknown at present"  unknown at present ., .-..

Assembly members:
LIRAGLUTIDE, polymer, 31 residues, 3751.20 Da.
N-hexadecanoyl-L-glutamic acid, non-polymer, 385.538 Da.

Natural source:   Common Name: baker   Taxonomy ID: 4932   Superkingdom: not available   Kingdom: not available   Genus/species: Eukaryota Fungi

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):
LIRAGLUTIDE: HAEGTFTSDVSSYLEGQAAK EFIAWLVRGRG

Data sets:
Data typeCount
1H chemical shifts196

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1LIRAGLUTIDE1
2N-HEXADECANOYL-L-GLUTAMIC ACID2

Entities:

Entity 1, LIRAGLUTIDE 31 residues - 3751.20 Da.

1   HISALAGLUGLYTHRPHETHRSERASPVAL
2   SERSERTYRLEUGLUGLYGLNALAALALYS
3   GLUPHEILEALATRPLEUVALARGGLYARG
4   GLY

Entity 2, N-HEXADECANOYL-L-GLUTAMIC ACID - C21 H39 N O5 - 385.538 Da.

1   D6M

Samples:

sample_1: LIRAGLUTIDE, [U-13C; U-15N], 1.6 mM

sample_conditions_1: ionic strength: 0.0 mM; pH: 7.900; pressure: 1.000 atm; temperature: 300.000 K

Experiments:

NameSampleSample stateSample conditions
NOESYsample_1solutionsample_conditions_1
TOCSYsample_1solutionsample_conditions_1

Software:

AutoDep v4.3, AutoDep - collection

CNX vany, CNX - chemical shift assignment

PRONTO vany, Kjur, Andersen and Poulsen - chemical shift assignment

X-PLOR vany, Brunger - chemical shift assignment

NMR spectrometers:

  • Bruker AMX 600 MHz

Related Database Links:

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