BMRB Entry 18426
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PDB ID: 2lsb
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR18426
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Title: Solution-state NMR structure of the human prion protein PubMed: 22676969
Deposition date: 2012-04-26 Original release date: 2012-06-18
Authors: Biljan, Ivana; Ilc, Gregor; Giancin, Gabriele; Zhukov, Igor; Plavec, Janez; Legname, Guiseppe
Citation: Biljan, Ivana; Giachin, Gabriele; Ilc, Gregor; Zhukov, Igor; Plavec, Janez; Legname, Giuseppe. "Structural basis for the protective effect of the human prion protein carrying the dominant-negative E219K polymorphism." Biochem. J. 446, 243-251 (2012).
Assembly members:
entity, polymer, 142 residues, 16169.103 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
entity: GQGGGTHSQWNKPSKPKTNM
KHMAGAAAAGAVVGGLGGYM
LGSAMSRPIIHFGSDYEDRY
YRENMHRYPNQVYYRPMDEY
SNQNNFVHDCVNITIKQHTV
TTTTKGENFTETDVKMMERV
VEQMCITQYERESQAYYQRG
SS
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 461 |
| 15N chemical shifts | 150 |
| 1H chemical shifts | 930 |
Additional metadata:
Related Database Links:
| BMRB | 15676 16743 16757 17714 17756 17757 17780 18550 19268 4379 4402 4434 4620 4641 4736 |
| PDB | 1E1G 1E1J 1E1P 1E1S 1E1U 1E1W 1FKC 1FO7 1H0L 1HJM 1HJN 1I4M 1QLX 1QLZ 1QM0 1QM1 1QM2 1QM3 2K1D 2KUN 2LEJ 2LFT 2LSB 2LV1 2M8T 2W9E 3HAF 3HAK 3HEQ 3HER 3HES 3HJ5 3HJX 4DGI 4KML 4N9O |
| DBJ | BAA00011 BAF62360 BAG32276 BAG32277 BAG32278 |
| EMBL | CAA58442 CAG46836 CAG46869 CAH92912 |
| GB | AAA19664 AAA60182 AAA68632 AAA68633 AAB59442 |
| REF | NP_000302 NP_001009093 NP_001073590 NP_001073591 NP_001073592 |
| SP | P04156 P40252 P40256 P61766 P61767 |
| TPE | CAJ43808 |
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