BMRB Entry 18500
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PDB ID: 2ltx
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR18500
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Title: Smurf1 WW2 domain in complex with a Smad7 derived peptide. PubMed: 22921829
Deposition date: 2012-06-04 Original release date: 2012-11-19
Authors: Macias, Maria; Aragon, Eric; Goerner, Nina; Xi, Qiaoran; Lopes, Tiago; Gao, Sheng; Massague, Joan
Citation: Aragon, Eric; Goerner, Nina; Xi, Qiaoran; Gomes, Tiago; Gao, Sheng; Massague, Joan; Macias, Maria. "Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-beta Pathways" Structure 20, 1726-1736 (2012).
Assembly members:
SMURF1WW2, polymer, 35 residues, 4057.533 Da.
SMAD7, polymer, 15 residues, 1778.969 Da.
Natural source: Common Name: Humans Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
SMURF1WW2: GPLPPGWEVRSTVSGRIYFV
DHNNRTTQFTDPRLH
SMAD7: ELESPPPPYSRYPMD
- assigned_chemical_shifts
| Data type | Count |
| 1H chemical shifts | 281 |
Additional metadata:
Related Database Links:
| BMRB | 17543 16923 18501 18502 |
| PDB | 2LB1 2LTX 2DJY 2KXQ 2LTY 2LTZ |
| DBJ | BAB13451 BAB29770 BAE32623 BAG11347 BAG11040 |
| EMBL | CAF92291 CAA04182 CAA04183 CAG12446 CDQ87305 CDQ93148 |
| GB | AAC62434 AAF08298 AAH29097 AAI36805 AAI44415 AAB81246 AAB81353 AAB81354 AAC25062 AAD41130 |
| REF | NP_001033716 NP_001103068 NP_001186776 NP_001244560 NP_065162 NP_001036125 NP_001153135 NP_001177750 NP_001231104 NP_001268265 |
| SP | Q9CUN6 Q9HCE7 O15105 O35253 O88406 |
| TPG | DAA15146 DAA15864 |