BMRB Entry 18501
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PDB ID: 2lty
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_anomalous, AVS_full
BMRB Entry DOI: doi:10.13018/BMR18501
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Title: NEDD4L WW2 domain in complex with a Smad7 derived peptide. PubMed: 22921829
Deposition date: 2012-06-04 Original release date: 2012-11-19
Authors: Macias, Maria; Aragon, Eric; Goerner, Nina; Xi, Qiaoran; Lopes, Tiago; Gao, Sheng; Massague, Joan
Citation: Aragon, Eric; Goerner, Nina; Xi, Qiaoran; Gomes, Tiago; Gao, Sheng; Massague, Joan; Macias, Maria. "Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-beta Pathways" Structure 20, 1726-1736 (2012).
Assembly members:
NEDD4LWW2, polymer, 34 residues, 3966.401 Da.
SMAD7, polymer, 15 residues, 1778.969 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
NEDD4LWW2: PGLPSGWEERKDAKGRTYYV
NHNNRTTTWTRPIG
SMAD7: ELESPPPPYSRYPMD
- assigned_chemical_shifts
Data type | Count |
1H chemical shifts | 327 |
Additional metadata:
Related Database Links:
BMRB | 17544 16923 18500 18502 |
PDB | 1WR4 2LB2 2LTY 2DJY 2KXQ 2LTX 2LTZ |
GB | ABU94641 AAB81246 AAB81353 AAB81354 AAC25062 AAD41130 |
DBJ | BAG11040 |
EMBL | CAA04182 CAA04183 CAG12446 CDQ87305 CDQ93148 |
REF | NP_001036125 NP_001153135 NP_001177750 NP_001231104 NP_001268265 |
SP | O15105 O35253 O88406 |
TPG | DAA15864 |