BMRB Entry 18596
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PDB ID: 2lvz
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR18596
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Title: Solution structure of a Eosinophil Cationic Protein-trisaccharide heparin mimetic complex PubMed: 23025322
Deposition date: 2012-07-17 Original release date: 2013-07-29
Authors: Garcia Mayoral, Maria Flor; Canales, Angeles; Diaz, Dolores; Lopez Prados, Javier; Moussaoui, Mohammed; de Paz, Jose Luis; Angulo, Jesus; Nieto, Pedro Manuel; Jimenez Barbero, Jesus; Boix, Ester; Bruix, Marta
Citation: Garcia Mayoral, Maria Flor; Canales, Angeles; Diaz, Dolores; Lopez Prados, Javier; Moussaoui, Mohammed; de Paz, Jose Luis; Angulo, Jesus; Nieto, Pedro Manuel; Jimenez Barbero, Jesus; Boix, Ester; Bruix, Marta. "Insights into the glycosaminoglycan-mediated cytotoxic mechanism of eosinophil cationic protein revealed by NMR" ACS Chem. Biol. 8, 144-151 (2013).
Assembly members:
Eosinophil_Cationic_Protein, polymer, 133 residues, 15598.974 Da.
SUGAR_(3-MER), polymer, 3 residues, 595.473 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
Eosinophil_Cationic_Protein: RPPQFTRAQWFAIQHISLNP
PRCTIAMRAINNYRWRCKNQ
NTFLRTTFANVVNVCGNQSI
RCPHNRTLNNCHRSRFRVPL
LHCDLINPGAQNISNCRYAD
RPGRRFYVVACDNRDPRDSP
RYPVVPVHLDTTI
SUGAR_(3-MER): XXX
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 410 |
| 15N chemical shifts | 148 |
| 1H chemical shifts | 923 |
Additional metadata:
Related Database Links:
| BMRB | 15757 |
| PDB | 1DYT 1H1H 1QMT 2KB5 2LVZ 4A2O 4A2Y 4OWZ 4OXB 4OXF |
| EMBL | CAA33251 CAA34545 CAA39462 |
| GB | AAA50283 AAC50143 AAC50150 AAG09050 AAG09051 |
| REF | NP_002926 XP_004054906 XP_004054907 |
| SP | P12724 P47778 P47780 |
| TPE | CDG31917 CDG31938 |
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