BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
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BMRB Entry 18599

Title: Solution structure of CCP modules 11-12 of complement factor H   PubMed: 23017427

Deposition date: 2012-07-18 Original release date: 2012-10-18

Authors: Makou, Elisavet; Mertens, Haydyn; Maciejewski, Mateusz; Soares, Dinesh; Matis, Ilias; Schmidt, Christoph; Herbert, Andrew; Svergun, Dmitri; Barlow, Paul; Herbert, C

Citation: Makou, Elisavet; Mertens, Haydyn; Maciejewski, Mateusz; Soares, Dinesh; Matis, Ilias; Schmidt, Christoph; Herbert, Andrew; Svergun, Dmitri; Barlow, Paul. "Solution structure of CCP modules 10-12 illuminates functional architecture of the complement regulator, factor H."  J. Mol. Biol. 424, 295-312 (2012).

Assembly members:
FH11-12, polymer, 127 residues, 14085.6893 Da.

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:   Production method: recombinant technology   Host organism: KOMAGATAELLA PASTORIS

Entity Sequences (FASTA):
FH11-12: EAEAAGVQSCGPPPELLNGN VKEKTKEEYGHSEVVEYYCN PRFLMKGPNKIQCVDGEWTT LPVCIVEESTCGDIPELEHG WAQLSSPPYYYGDSVEFNCS ESFTMIGHRSITCIHGVWTQ LPQCVAI

Data sets:
Data typeCount
13C chemical shifts550
15N chemical shifts125
1H chemical shifts839

Additional metadata:

  • Assembly
  • Samples and Experiments
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Related Database Links:

UniProt CFAH_HUMAN
PDB 4B2S

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