BMRB Entry 18649
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PDB ID: 2lz3
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR18649
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Title: Transmembrane domain of Amyloid precursor protein WT PubMed: 24390130
Deposition date: 2012-08-07 Original release date: 2012-09-07
Authors: Chen, Wen; Wang, Chunyu
Citation: Chen, Wen; Gamache, Eric; Rosenman, David; Xie, Jian; Lopez, Maria; Li, Yue-Ming; Wang, Chunyu. "Familial Alzheimer's mutations within APPTM increase A42 production by enhancing accessibility of -cleavage site." Nat. Commun. 5, 3037-3037 (2014).
Assembly members:
wild type monomer, polymer, 32 residues, Formula weight is not available
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
wild type monomer: GAMAKGAIIGLMVGGVVIAT
VIVITLVMLKKK
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 144 |
| 15N chemical shifts | 30 |
| 1H chemical shifts | 252 |
Additional metadata:
Related Database Links:
| BMRB | 15775 18080 |
| PDB | 2LLM 2LOH 2LP1 2LZ3 |
| DBJ | BAA22264 BAA24230 BAA84580 BAB71958 BAC34997 |
| EMBL | CAA30050 CAA30488 CAA31830 CAA39589 CAA39590 |
| GB | AAA35540 AAA36829 AAA37139 AAA51722 AAA51726 |
| PIR | A60045 D60045 E60045 G60045 JH0773 |
| PRF | 1303338A 1403400A 1507304A 1507304B 1507304C |
| REF | NP_000475 NP_001005698 NP_001006601 NP_001013036 NP_001070264 |
| SP | P05067 P08592 P12023 P53601 P79307 |
| TPG | DAA33655 |
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