BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
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BMRB Entry 18654

Title: NMR Structures of Single-chain Insulin

Deposition date: 2012-08-09 Original release date: 2012-09-07

Authors: Weiss, Michael; Yang, Yanwu

Citation: Yang, Yanwu; Wan, Zhu-li; Hua, Qing-xin; Phillips, Nelson; Huang, Kun; Yeh, I-Ju; Liu, Yule; Hu, Shi-Quan; Hattier, Thomas; Whittaker, Jonathan; Weiss, Michael. "Dynamic repair of an amyloidogenic protein: insulin fibrillation is blocked by tethering a nascent alpha-helix"  Not known ., .-..

Assembly members:
Single-chain Insulin, polymer, 57 residues, 6382.218 Da.

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:   Production method: recombinant technology   Host organism: Pichia pastoris

Entity Sequences (FASTA):
Single-chain Insulin: FVNQHLCGSDLVEALYLVCG ERGFFYTDPTGGGPRRGIVE QCCHSICSLYQLENYCN

Data sets:
Data typeCount
13C chemical shifts191
15N chemical shifts54
1H chemical shifts368

Additional metadata:

  • Assembly
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  • Spectrometers
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Related Database Links:

PDB 2JZQ 2LWZ

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