BMRB Entry 18694
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PDB ID: 2lxs
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, SPARTA
BMRB Entry DOI: doi:10.13018/BMR18694
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Title: Allosteric communication in the KIX domain proceeds through dynamic re-packing of the hydrophobic core PubMed: 23651431
Deposition date: 2012-08-31 Original release date: 2013-06-04
Authors: Bruschweiler, Sven; Schanda, Paul; Konrat, Robert; Tollinger, Martin
Citation: Bruschweiler, Sven; Konrat, Robert; Tollinger, Martin. "Allosteric Communication in the KIX Domain Proceeds through Dynamic Repacking of the Hydrophobic Core." ACS Chem. Biol. 8, 1600-1610 (2013).
Assembly members:
KIX_1, polymer, 87 residues, 10353.954 Da.
KIX_2, polymer, 19 residues, 2061.352 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
KIX_1: GVRKGWHEHVTQDLRSHLVH
KLVQAIFPTPDPAALKDRRM
ENLVAYAKKVEGDMYESANS
RDEYYHLLAEKIYKIQKELE
EKRRSRL
KIX_2: DAGNILPSDIMDFVLKNTP
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 437 |
| 15N chemical shifts | 108 |
| 1H chemical shifts | 675 |
Additional metadata:
Related Database Links:
| BMRB | 16851 18314 18315 18695 18695 |
| PDB | 1KDX 1SB0 2AGH 2KWF 2LQH 2LQI 2LXS 2LXT |
| DBJ | BAE06125 BAG65526 BAI45616 BAD92745 |
| GB | AAB28651 AAC08447 AAC51331 AAC51770 AAH72594 AAA58669 AAA62593 AAQ63624 ABM46715 ABM54290 |
| PRF | 1923401A |
| REF | NP_001020603 NP_001073315 NP_001157494 NP_001247644 NP_004371 NP_001074518 NP_001184033 NP_005924 XP_001093874 XP_002188579 |
| SP | P45481 Q6JHU9 Q92793 P55200 Q03164 |
| TPG | DAA15549 DAA22311 |
| EMBL | CAA93625 |
| PIR | A48205 |
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