BMRB Entry 18709
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PDB ID: 2ly4
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_anomalous, AVS_full, LACS, SPARTA
BMRB Entry DOI: doi:10.13018/BMR18709
MolProbity Validation Chart
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Title: HMGB1-facilitated p53 DNA binding occurs via HMG-box/p53 transactivation domain interaction and is regulated by the acidic tail PubMed: 23063560
Deposition date: 2012-09-12 Original release date: 2012-10-29
Authors: Rowell, John; Simpson, Kathryn; Stott, Katherine; Watson, Matthew; Thomas, Jean
Citation: Rowell, John; Simpson, Kathryn; Stott, Katherine; Watson, Matthew; Thomas, Jean. "HMGB1-facilitated p53 DNA binding occurs via HMG-Box/p53 transactivation domain interaction, regulated by the acidic tail." Structure 20, 2014-2024 (2012).
Assembly members:
entity_1, polymer, 83 residues, 9705.259 Da.
entity_2, polymer, 93 residues, 9979.1 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
entity_1: GKGDPKKPRGKMSSYAFFVQ
TCREEHKKKHPDASVNFSEF
SKKCSERWKTMSAKEKGKFE
DMAKADKARYEREMKTYIPP
KGE
entity_2: MEEPQSDPSVEPPLSQETFS
DLWKLLPENNVLSPLPSQAM
DDLMLSPDDIEQWFTEDPGP
DEAPRMPEAAPPVAPAPAAP
TPAAPAPAPSWPL
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 749 |
| 15N chemical shifts | 159 |
| 1H chemical shifts | 1172 |
Additional metadata:
Related Database Links:
| BMRB | 11147 11532 15148 15149 15502 4079 17073 17760 |
| PDB | 1AAB 1CKT 2LY4 2RTU 2YRQ 4QR9 2GS0 2L14 |
| DBJ | BAA09924 BAC29902 BAC34367 BAC34773 BAC38678 BAC16799 BAG35463 BAG64357 BAI45431 BAJ52715 |
| EMBL | CAA31110 CAA31284 CAA56631 CAA68441 CAA68526 CAA26306 CAA38095 CAA42625 CAA42626 CAA42627 |
| GB | AAA20508 AAA31050 AAA40729 AAA57042 AAA64970 AAA59987 AAA59988 AAA59989 AAA61211 AAA61212 |
| PIR | S29857 |
| REF | NP_001002937 NP_001004034 NP_001075304 NP_001102843 NP_001162380 NP_000537 NP_001119584 NP_001119585 NP_001119586 NP_001119590 |
| SP | A9RA84 B0CM99 B1MTB0 P07156 P09429 P04637 Q9TTA1 |
| TPG | DAA21468 DAA23902 |
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