BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
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BMRB Entry 18720

Title: The solution structure of the Dm DCP1 EVH1 domain in complex with the XRN1 DBM peptide   PubMed: 23142987

Deposition date: 2012-09-17 Original release date: 2012-10-15

Authors: Truffault, Vincent

Citation: Braun, Joerg; Truffault, Vincent; Boland, Andreas; Huntzinger, Eric; Chang, Chung-Te; Haas, Gabrielle; Weichenrieder, Oliver; Coles, Murray; Izaurralde, Elisa. "A direct interaction between DCP1 and XRN1 couples mRNA decapping to 5' exonucleolytic degradation."  Nat. Struct. Mol. Biol. 19, 1324-1331 (2012).

Assembly members:
Dm_DCP1_EVH1_domain, polymer, 133 residues, 15361.304 Da.
XRN1_DBM, polymer, 38 residues, 4355.992 Da.

Natural source:   Common Name: Fruit fly   Taxonomy ID: 7227   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Drosophila melanogaster

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli

Entity Sequences (FASTA):
Dm_DCP1_EVH1_domain: GPHMADLMADESITRMNLAA IKKIDPYAKEIVDSSSHVAF YTFNSSQNEWEKTDVEGAFF IYHRNAEPFHSIFINNRLNT TSFVEPITGSLELQSQPPFL LYRNERSRIRGFWFYNSEEC DRISGLVNGLLKSK
XRN1_DBM: GPQDPLLQQQRAPFPGQMPN LPKPPLFWQQEAQKQEAL

Data sets:
Data typeCount
13C chemical shifts524
15N chemical shifts123
1H chemical shifts18

Additional metadata:

  • Assembly
  • Samples and Experiments
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Related Database Links:

PDB 2LYD
GB AAF47089 AAX94785 ACL88332 ACZ94554 EDV56888 AAF48958 AAK93099 ACZ95330
REF NP_001163282 NP_611842 XP_001976488 XP_002040166 XP_002045212 NP_001162796 NP_523408
EMBL CAB43711