BMRB Entry 18816
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PDB ID: 2m0p
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR18816
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Title: Solution structure of the tenth complement type repeat of human megalin PubMed: 23275343
Deposition date: 2012-11-01 Original release date: 2013-01-07
Authors: Dagil, Robert; Kragelund, Birthe
Citation: Dagil, Robert; Nykjaer, Charlotte; Bonvin, Anders; Kragelund, Alexandre M J J. "Gentamicin binds to the megalin receptor as a competitive inhibitor using the common ligand binding motif of complement type repeats: insight from the nmr structure of the 10th complement type repeat domain alone and in complex with gentamicin." J. Biol. Chem. 288, 4424-4435 (2013).
Assembly members:
CR10, polymer, 52 residues, 5045.292 Da.
CALCIUM ION, non-polymer, 40.078 Da.
Natural source: Common Name: Humans Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Pichia pastoris
Entity Sequences (FASTA):
CR10: THAPASCLDTQYTCDNHQCI
SKNWVCDTDNDCGDGSDEKN
CNSTETHHHHHH
- assigned_chemical_shifts
Data type | Count |
13C chemical shifts | 164 |
15N chemical shifts | 44 |
1H chemical shifts | 243 |
Additional metadata:
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