BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
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BMRB Entry 18816

Title: Solution structure of the tenth complement type repeat of human megalin   PubMed: 23275343

Deposition date: 2012-11-01 Original release date: 2013-01-07

Authors: Dagil, Robert; Kragelund, Birthe

Citation: Dagil, Robert; Nykjaer, Charlotte; Bonvin, Anders; Kragelund, Alexandre M J J. "Gentamicin binds to the megalin receptor as a competitive inhibitor using the common ligand binding motif of complement type repeats: insight from the nmr structure of the 10th complement type repeat domain alone and in complex with gentamicin."  J. Biol. Chem. 288, 4424-4435 (2013).

Assembly members:
CR10, polymer, 52 residues, 5045.292 Da.
CALCIUM ION, non-polymer, 40.078 Da.

Natural source:   Common Name: Humans   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:   Production method: recombinant technology   Host organism: Pichia pastoris

Entity Sequences (FASTA):
CR10: THAPASCLDTQYTCDNHQCI SKNWVCDTDNDCGDGSDEKN CNSTETHHHHHH

Data sets:
Data typeCount
13C chemical shifts164
15N chemical shifts44
1H chemical shifts243

Additional metadata:

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Related Database Links:

PDB 2M0P

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