BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
Member of WWPDB

BMRB Entry 19079

Title: Solution structure of the 2A proteinase from a common cold agent, human rhinovirus RV-C02, strain W12   PubMed: 24937088

Deposition date: 2013-03-07 Original release date: 2014-03-14

Authors: Lee, Woonghee; Frederick, Ronnie; Tonelli, Marco; Troupis, Andrew; Reinin, Nichole; Suchy, Fabian; Moyer, Kylie; Watters, Kelly; Aceti, David; Palmenberg, Ann; Markley, John

Citation: Lee, Woonghee; Watters, Kelly; Troupis, Andrew; Reinen, Nichole; Suchy, Fabian; Moyer, Kylie; Frederick, Ronnie; Tonelli, Marco; Aceti, David; Palmenberg, Ann; Markley, John. "Solution Structure of the 2A Protease from a Common Cold Agent, Human Rhinovirus C2, Strain W12."  PLoS ONE 9, e97198-e97198 (2014).

Assembly members:
2A_proteinase, polymer, 142 residues, 15552.405 Da.
ZINC ION, non-polymer, 65.409 Da.
5-benzyl-1,3-thiazol-2-amine, non-polymer, 190.265 Da.
(2S)-2-amino-3-methyl-1-{4-[3-(thiophen-2-yl)-1,2,4-oxadiazol-5-yl]piperidin-1-yl}butan-1-one, non-polymer, 334.436 Da.

Natural source:   Common Name: Humans   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli

Entity Sequences (FASTA):
2A_proteinase: GPSDLFVHTEQAIYKNAHLT TPNDQTILLALTADLQIDGC DQPGPDNIPDCDCTSGCYYS RSLDRYIPVECEAHDWYPVE ETQYYPKHIQYNLLIGEGPC VPGDAGGKLLCRHGVIGIIT AGGDGHVAFTDLRPYNIKAT SQ

Data sets:
Data typeCount
13C chemical shifts515
15N chemical shifts125
1H chemical shifts845

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Related Database Links:

PDB 2M5T
GB ABQ51392 AET25086 AET72466 AET85046 AFD64770

Download simulated HSQC data in one of the following formats:
CSV: Backbone or all simulated shifts
SPARKY: Backbone or all simulated shifts