BMRB Entry 19319
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PDB ID: 2ma2
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS, SPARTA
BMRB Entry DOI: doi:10.13018/BMR19319
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Title: Solution structure of RasGRP2 EF hands bound to calcium PubMed: 23908768
Deposition date: 2013-06-24 Original release date: 2013-08-26
Authors: Kuriyan, John; Iwig, Jeffrey; Vercoulen, Yvonne; Das, Rahul; Barros, Tiago; Limnander, Andre; Che, Yan; Pelton, Jeffrey; Wemmer, David; Roose, Jeroen
Citation: Iwig, Jeffrey; Vercoulen, Yvonne; Das, Rahul; Barros, Tiago; Limnander, Andre; Che, Yan; Pelton, Jeffrey; Wemmer, David; Roose, Jeroen; Kuriyan, John. "Structural analysis of autoinhibition in the Ras-specific exchange factor RasGRP1" eLife 2, e00813-e00813 (2013).
Assembly members:
RasGRP2, polymer, 81 residues, 18412.633 Da.
CALCIUM ION, non-polymer, 40.078 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
RasGRP2: KLDQALVVEHIEKMVESVFR
NFDVDGDGHISQEEFQIIRG
NFPYLSAFGDLDQNQDGCIS
REEMVSYFLRSSSVLGGRMG
F
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 304 |
| 15N chemical shifts | 77 |
| 1H chemical shifts | 386 |
Additional metadata:
Related Database Links:
| PDB | 2MA2 |
| DBJ | BAC28797 BAG37199 BAG52620 BAG53672 BAJ21074 |
| EMBL | CAA73005 CAA73008 |
| GB | AAC79697 AAC79698 AAD12741 AAD12742 AAF07219 |
| REF | NP_001076446 NP_001092140 NP_001092141 NP_001162561 NP_001164963 |
| SP | P0C643 Q7LDG7 Q9QUG9 |
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