BMRB Entry 19391
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PDB ID: 2mb7
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS, SPARTA
BMRB Entry DOI: doi:10.13018/BMR19391
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Title: Solution structure of MBD3 methylcytosine binding domain while bound to hydroxymethylated DNA PubMed: 24307175
Deposition date: 2013-07-26 Original release date: 2013-12-09
Authors: Williams, David; Scarsdale, J.
Citation: Cramer, Jason; Scarsdale, J. Neel; Walavalkar, Ninad; Buchwald, William; Ginder, Gordon; Williams, David. "Probing the Dynamic Distribution of Bound States for Methylcytosine-binding Domains on DNA." J. Biol. Chem. 289, 1294-1302 (2014).
Assembly members:
MBD3, polymer, 72 residues, 8342.584 Da.
hDNA_A, polymer, 17 residues, Formula weight is not available
hDNA_B, polymer, 17 residues, Formula weight is not available
Natural source: Common Name: human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
MBD3: GSMERKRWECPALPQGWERE
EVPRRSGLSAGHRDVFYYSP
SGKKFRSKPQLARYLGGSMD
LSTFDFRTGKML
hDNA_A: GAGGCGCTXGGCGGCAG
hDNA_B: CTGCCGCXGAGCGCCTC
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 309 |
| 15N chemical shifts | 68 |
| 1H chemical shifts | 437 |
Additional metadata:
Related Database Links:
| PDB | 2MB7 |
| DBJ | BAF83571 BAI46781 |
| GB | AAC68876 AAC68877 AAC72104 AAD48909 EAW69477 |
| REF | NP_001102205 NP_001180972 NP_001268382 NP_038623 XP_002723919 |
| SP | O95983 Q9Z2D8 |
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