BMRB Entry 19395
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PDB ID: 2mbc
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_anomalous, AVS_full, SPARTA
BMRB Entry DOI: doi:10.13018/BMR19395
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Title: Solution Structure of human holo-PRL-3 in complex with vanadate
Deposition date: 2013-07-29 Original release date: 2013-10-08
Authors: Jeong, Ki-Woong; Kang, Dong-Il; Kim, Jin-Kyoung; Shin, Soyoung; Jin, Bonghwan; Lee, Chung-Kyoung; Kim, Eun-Hee; Jeon, Young; Kim, Yangmee
Citation: Kim, Kyoung-Ah; Song, Jin-Sue; Jee, Jungoo; Sheen, Mee; Lee, Chulhyun; Lee, Tae; Ro, Seonggu; Cho, Joong; Lee, Weontae; Yamazaki, Toshio; Jeon, Young; Cheong, Chaejoon. "Structure of human PRL-3, the phosphatase associated with cancer metastasis" FEBS Lett. ., .-..
Assembly members:
holo-PRL-3_in_complex_with_vanadate, polymer, 162 residues, 18268.441 Da.
(2S)-2-amino-3-methyl-1-{4-[3-(thiophen-2-yl)-1,2,4-oxadiazol-5-yl]piperidin-1-yl}butan-1-one, non-polymer, 334.436 Da.
4-[(E)-(4-hydroxynaphthalen-1-yl)diazenyl]benzenesulfonic acid, non-polymer, 328.342 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
holo-PRL-3_in_complex_with_vanadate: MARMNRPAPVEVSYKHMRFL
ITHNPTNATLSTFIEDLKKY
GATTVVRVCEVTYDKTPLEK
DGITVVDWPFDDGAPPPGKV
VEDWLSLVKAKFCEAPGSCV
AVHCVAGLGRAPVLVALALI
ESGMKYEDAIQFIRQKRRGA
INSKQLTYLEKYRPKQRLRF
KD
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 427 |
| 15N chemical shifts | 130 |
| 1H chemical shifts | 913 |
Additional metadata:
Related Database Links:
| PDB | 1R6H 1V3A 2MBC |
| DBJ | BAJ20896 |
| GB | AAC29314 EHH25482 EHH64453 |
| REF | NP_001180623 NP_116000 XP_001500033 XP_002819531 XP_003819536 |
| SP | O75365 |
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