BMRB Entry 19423
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PDB ID: 2mc1
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, SPARTA
BMRB Entry DOI: doi:10.13018/BMR19423
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Title: Solution structure of the Vav1 SH2 domain complexed with a Syk-derived singly phosphorylated peptide PubMed: 23955592
Deposition date: 2013-08-13 Original release date: 2013-08-26
Authors: Chen, Chih-Hong; Piraner, Dan; Gorenstein, Nina; Geahlen, Robert; Post, Carol
Citation: Chen, Chih-Hong; Piraner, Dan; Gorenstein, Nina; Geahlen, Robert; Beth Post, Carol. "Differential recognition of syk-binding sites by each of the two phosphotyrosine-binding pockets of the Vav SH2 domain." Biopolymers 99, 897-907 (2013).
Assembly members:
entity_1, polymer, 106 residues, 12335.253 Da.
entity_2, polymer, 13 residues, 1594.495 Da.
O-PHOSPHOTYROSINE, non-polymer, 261.168 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
entity_1: HMQDLSVHLWYAGPMERAGA
ESILANRSDGTFLVRQRVKD
AAEFAISIKYNVEVKHIKIM
TAEGLYRITEKKAFRGLTEL
VEFYQQNSLKDCFKSLDTTL
QFPFKE
entity_2: DTEVYESPXADPE
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 315 |
| 15N chemical shifts | 92 |
| 1H chemical shifts | 681 |
Additional metadata:
Related Database Links:
| BMRB | 17632 |
| PDB | 2CRH 2LCT 2MC1 2ROR |
| DBJ | BAG36112 BAG62721 BAJ21026 |
| EMBL | CAA34383 CAA58783 |
| GB | AAC25011 AAH13361 AAI23647 AIC59346 EAW69057 |
| REF | NP_001071542 NP_001245135 NP_001245136 NP_001254762 NP_005419 |
| SP | P15498 Q08DN7 |
| TPG | DAA27902 |
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