BMRB Entry 19425
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PDB ID: 2mc2
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS, SPARTA
BMRB Entry DOI: doi:10.13018/BMR19425
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Title: X-ray crystallography-solution NMR hybrid structure of mouse RyR2 domain A. PubMed: 23978697
Deposition date: 2013-08-13 Original release date: 2013-09-10
Authors: Amador, Fernando; Stathopulos, Peter; Seabrook, Genevieve; Ikura, Mitsuhiko
Citation: Amador, Fernando; Kimlicka, Lynn; Stathopulos, Peter; Gasmi-Seabrook, Genevieve; Maclennan, David; Van Petegem, Filip; Ikura, Mitsuhiko. "Type 2 Ryanodine Receptor Domain A Contains a Unique and Dynamic -Helix That Transitions to a -Strand in a Mutant Linked with a Heritable Cardiomyopathy." J. Mol. Biol. 425, 4034-4046 (2013).
Assembly members:
entity, polymer, 219 residues, 23049.213 Da.
Natural source: Common Name: Mouse Taxonomy ID: 10090 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Mus musculus
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
entity: GSGSEIQFLRTDDEVVLQCT
ATIHKEQQKLCLAAEGFGNR
LCFLESTSNSKNVPPDLSIC
TFVLEQSLSVRALQEMLANT
VEKSEGQVDVEKWKFMMKTA
QGGGHRTLLYGHAILLRHSY
SGMYLCCLSTSRSSTDKLAF
DVGLQEDTTGEACWWTIHPA
SKQRSEGEKVRVGDDLILVS
VSSERYLHLSYGNSSWHVDA
AFQQTLWSVAPISSGSEAA
- assigned_chemical_shifts
Data type | Count |
13C chemical shifts | 541 |
15N chemical shifts | 185 |
1H chemical shifts | 185 |
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