BMRB Entry 19817
Click here to enlarge.
PDB ID: 2mlf
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS, SPARTA
BMRB Entry DOI: doi:10.13018/BMR19817
MolProbity Validation Chart
NMR-STAR file interactive viewer.
NMR-STAR v3 text file.
NMR-STAR v2.1 text file (deprecated)
XML gzip file.
RDF gzip file.
All files associated with the entry
Title: NMR structure of the dilated cardiomyopathy mutation G159D in troponin C bound to the anchoring region of troponin I PubMed: 18803402
Deposition date: 2014-02-26 Original release date: 2014-03-10
Authors: Baryshnikova, Olga; Robertson, Ian; Mercier, Pascal; Sykes, Brian
Citation: Baryshnikova, Olga; Robertson, Ian; Mercier, Pascal; Sykes, Brian. "The dilated cardiomyopathy G159D mutation in cardiac troponin C weakens the anchoring interaction with troponin I." Biochemistry 47, 10950-10960 (2008).
Assembly members:
cCTnC, polymer, 72 residues, 8427.296 Da.
CALCIUM ION, non-polymer, 40.078 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
cCTnC: MGKSEEELSDLFRMFDKNAD
GYIDLDELKIMLQATGETIT
EDDIEELMKDGDKNNDGRID
YDEFLEFMKDVE
- assigned_chemical_shifts
| Data type | Count |
| 1H chemical shifts | 439 |
| 13C chemical shifts | 221 |
| 15N chemical shifts | 76 |
Additional metadata:
Related Database Links:
| BMRB | 15385 15388 15400 15427 17243 17440 19816 25120 |
| PDB | 1DTL 1IH0 1J1D 1J1E 1OZS 2JT0 2JT3 2JT8 2JTZ 2KDH 2L98 2MLE 2MLF |
| DBJ | BAG36483 |
| EMBL | CAA30736 CAG46663 CAG46683 |
| GB | AAA36772 AAA37492 AAA37493 AAB91994 AAH30244 |
| PIR | TPHUCC |
| PRF | 1510257A 750650A |
| REF | NP_001029277 NP_001029523 NP_001123715 NP_001272501 NP_003271 |
| SP | P02591 P19123 P63315 P63316 P63317 |
| TPG | DAA16908 |
Download simulated HSQC data in one of the following formats:
CSV: Backbone
or all simulated shifts
SPARKY: Backbone
or all simulated shifts