BMRB Entry 19824
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PDB ID: 4crp
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR19824
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Title: Solution structure of a TrkAIg2 domain construct for use in drug discovery
Deposition date: 2014-02-28 Original release date: 2015-01-12
Authors: Shoemark, D.; Fahey, M.; Williams, C.; Sessions, R.; Crump, Matthew; Allen-birt, S.; A., S.
Citation: Allen, S.; Watson, J.; Shoemark, D.; Barua, N.; Patel, N.. "GDNF, NGF and BDNF as therapeutic options for neurodegeneration." Pharmacology & Therapeutics ., .-..
Assembly members:
HIGH_AFFINITY_NERVE_GROWTH_FACTOR_RECEPTOR, polymer, 107 residues, 11776.0322 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
HIGH_AFFINITY_NERVE_GROWTH_FACTOR_RECEPTOR: DDDDDVSFCASVQLHTAVEM
HHWCIPFSVDGQPAPSLRWL
FNGSVLNETSFIFTEFLEPA
ANETVRHGCLRLNQPTHVNN
GNYTLLAANPCGQASASIMA
AFMDNPF
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 441 |
| 15N chemical shifts | 113 |
| 1H chemical shifts | 690 |
Additional metadata:
Related Database Links:
| UNP | NTRK1_HUMAN |
| PDB | 1HE7 1WWA 1WWW 2IFG 4CRP |
| DBJ | BAA34355 BAF83448 BAG35582 |
| GB | AAH62580 AAI36555 AAI44240 AHW56542 AHW56543 |
| REF | NP_001007793 NP_001012331 NP_002520 XP_001114243 XP_001145942 |
| SP | P04629 |
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