BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
Member of WWPDB

BMRB Entry 19998

Title: Solution structure of the sodium channel toxin Hd1a   PubMed: 25754331

Deposition date: 2014-06-01 Original release date: 2015-03-23

Authors: Klint, Julie; Mobli, Mehdi; King, Glenn

Citation: Klint, Julie; Vetter, Irina; Rupasinghe, Darshani; Er, Sing; Herzig, Volker; Mobli, Mehdi; Lewis, Richard; Bosmans, Frank; King, Glenn. "Seven novel modulators of the analgesic target Nav1.7 uncovered using a high-throughput venom-based discovery pipeline"  Br. J. Pharmacol. ., .-. (2015).

Assembly members:
Hd1a, polymer, 36 residues, 3891.489 Da.

Natural source:   Common Name: tarantula   Taxonomy ID: 1046906   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Haplopelma doriae

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli

Entity Sequences (FASTA):
Hd1a: GACLGFGKSCNPSNDQCCKS SSLACSTKHKWCKYEL

Data sets:
Data typeCount
1H chemical shifts222
13C chemical shifts138
15N chemical shifts38

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Related Database Links:

PDB 2MPQ

Download simulated HSQC data in one of the following formats:
CSV: Backbone or all simulated shifts
SPARKY: Backbone or all simulated shifts