BMRB Entry 25082
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PDB ID: 2mrk
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR25082
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Title: Fyn SH2 domain in complex with the natural inhibitory phosphotyrosine peptide
Deposition date: 2014-07-09 Original release date: 2015-07-13
Authors: Huculeci, Radu; Buts, Lieven; Lenaerts, Tom; van Nuland, Nico
Citation: Huculeci, Radu; Cilia, Elisa; Buts, Lieven; Houben, Klaartje; van Nuland, Nico; Lenaerts, Tom. "Dynamically coupled residues within the SH2 domain of FYN are key to unlock its activity" Not known ., .-..
Assembly members:
entity_1, polymer, 122 residues, 11690.439 Da.
entity_2, polymer, 10 residues, 1254.209 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
entity_1: MGSSHHHHHHSSGLVPRGSH
MEWYFGKLGRKDAERQLLSF
GNPRGTFLIRESETTKGAYS
LSIRDWDDMKGDHVKHYKIR
KLDNGGYYITTRAQFETLQQ
LVQHYSERAAGLCCRLVVPC
HK
entity_2: EPQYQPGENL
- assigned_chemical_shifts
| Data type | Count |
| 1H chemical shifts | 57 |
Additional metadata:
Related Database Links:
| BMRB | 25081 |
| PDB | 1AOT 1AOU 1G83 2MQI 2MRJ 2MRK 4U17 4U1P |
| DBJ | BAE33766 BAG70107 BAG70240 BAI46902 |
| EMBL | CAA36435 |
| GB | AAA36615 AAA49719 AAA82942 AAC08285 AAH32496 |
| REF | NP_001071440 NP_001073675 NP_001079077 NP_001080120 NP_001116365 |
| SP | A0JNB0 A1Y2K1 P06241 P13406 P39688 |
| TPG | DAA26259 |