BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
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BMRB Entry 25421

Title: NMR structure of spider toxin- G7W/N24S mutant of TRTX-Hhn2b   PubMed: 26429937

Deposition date: 2015-01-08 Original release date: 2015-12-21

Authors: Klint, Julie; Chin, Yanni; Mobli, Medhi

Citation: Klint, Julie; Chin, Yanni; Mobli, Medhi. "Rational Engineering Defines a Molecular Switch That Is Essential for Activity of Spider-Venom Peptides against the Analgesics Target NaV1.7"  Mol. Pharmacol. 88, 1002-1010 (2015).

Assembly members:
GWHhn2b, polymer, 34 residues, 3793.473 Da.

Natural source:   Common Name: Chinese bird spider   Taxonomy ID: 209901   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Haplopelma hainanum

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli

Entity Sequences (FASTA):
GWHhn2b: AECKGFWKSCVPGKNECCSG YACSSRDKWCKVLL

Data sets:
Data typeCount
13C chemical shifts145
15N chemical shifts35
1H chemical shifts222

Additional metadata:

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